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Antibodies & immune proteins (PDB): 55 3D models

DNA, RNA, nucleic-acid drugs, gene editing, proteins and 300+ real PDB structures (real sizes 1–100 nm). Each one is a ready-made 3D model you can turn, recolour and place in a figure — open BioDioRama and type its name in the Library search.

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Antibody IgG2a (intact) — Structure of immunoglobulin — X-ray structure, 1997 (PDB 1IGT), downloaded from the RCSB Protein Data Bank.
Human IgG1 antibody b12 (intact) — Crystal structure of the intact human igg b12 with broad and potent activity against primary hiv-1 isolates: a template for hiv vaccine d… — X-ray structure, 2001 (PDB 1HZH), downloaded from the RCSB Protein Data Bank.
Antibody IgG1 (intact) — Structure of immunoglobulin — X-ray structure, 1998 (PDB 1IGY), downloaded from the RCSB Protein Data Bank.
Pembrolizumab (anti-PD-1 IgG4) — Crystal structure of pembrolizumab, a full length igg4 antibody — X-ray structure, 2015 (PDB 5DK3), downloaded from the RCSB Protein Data Bank.
Trastuzumab Fab bound to HER2 — Crystal structure of extracellular domain of human her2 complexed with herceptin fab — X-ray structure, 2003 (PDB 1N8Z), downloaded from the RCSB Protein Data Bank.
Cetuximab Fab bound to EGFR — Structure of the extracellular domain of the epidermal growth factor receptor in complex with the fab fragment of cetuximab/erbitux/imc-c225 — X-ray structure, 2005 (PDB 1YY9), downloaded from the RCSB Protein Data Bank.
Bevacizumab Fab bound to VEGF — Vascular endothelial growth factor in complex with a neutralizing antibody — X-ray structure, 1999 (PDB 1BJ1), downloaded from the RCSB Protein Data Bank.
Antibody Fab bound to lysozyme — Structure of an antibody-antigen complex. crystal structure of the hy/hel-10 fab-lysozyme complex — X-ray structure, 1989 (PDB 3HFM), downloaded from the RCSB Protein Data Bank.
T-cell receptor bound to HLA-A2 — Complex between human t-cell receptor, viral peptide (tax), and hla-a 0201 — X-ray structure, 1997 (PDB 1AO7), downloaded from the RCSB Protein Data Bank.
MHC class I (HLA-B27) — The three-dimensional structure of hla-b27 at 2.1 angstroms resolution suggests a general mechanism for tight peptide binding to mhc — X-ray structure, 1992 (PDB 1HSA), downloaded from the RCSB Protein Data Bank.
MHC class II (HLA-DR1) — Crystal structure of the human class ii mhc protein hla-dr1 complexed with an influenza virus peptide — X-ray structure, 1994 (PDB 1DLH), downloaded from the RCSB Protein Data Bank.
PD-1 bound to PD-L1 — Structure of the complex of human programmed death-1 (pd-1) and its ligand pd-l1. — X-ray structure, 2015 (PDB 4ZQK), downloaded from the RCSB Protein Data Bank.
CTLA-4 bound to B7-1 — Human b7-1/ctla-4 co-stimulatory complex — X-ray structure, 2001 (PDB 1I8L), downloaded from the RCSB Protein Data Bank.
Tumour necrosis factor (TNF-α) — The structure of tumor necrosis factor-alpha at 2.6 angstroms resolution. implications for receptor binding — X-ray structure, 1990 (PDB 1TNF), downloaded from the RCSB Protein Data Bank.
Interleukin-2 — Crystal structure of human interleukin-2 — X-ray structure, 2002 (PDB 1M47), downloaded from the RCSB Protein Data Bank.
Interferon-γ — Three-dimensional structure of recombinant human interferon-gamma. — X-ray structure, 1992 (PDB 1HIG), downloaded from the RCSB Protein Data Bank.
Complement component C3 — Human complement component c3 — X-ray structure, 2005 (PDB 2A73), downloaded from the RCSB Protein Data Bank.
Complement C3b — Human complement component c3b — X-ray structure, 2006 (PDB 2I07), downloaded from the RCSB Protein Data Bank.
β2-Glycoprotein I (apolipoprotein H) — Crystal structure of human beta-2-glycoprotein-i (apolipoprotein-h) — X-ray structure, 1999 (PDB 1C1Z), downloaded from the RCSB Protein Data Bank.
TLR4–MD-2 bound to LPS — Crystal structure of the human tlr4-human md-2-e.coli lps ra complex — X-ray structure, 2009 (PDB 3FXI), downloaded from the RCSB Protein Data Bank.
ICAM-1 — Structure of the two amino-terminal domains of human intercellular adhesion molecule-1, icam-1 — X-ray structure, 1998 (PDB 1IAM), downloaded from the RCSB Protein Data Bank.
E-selectin bound to sialyl Lewis X — Crystal structure of e-selectin lectin/egf domains complexed with slex — X-ray structure, 2001 (PDB 1G1T), downloaded from the RCSB Protein Data Bank.
Lysozyme (hen egg white) — Real-space refinement of the structure of hen egg-white lysozyme — X-ray structure, 1977 (PDB 1LYZ), downloaded from the RCSB Protein Data Bank.
Protein A (B domain) — Staphylococcus aureus protein a, immunoglobulin-binding b domain, nmr, minimized average structure — NMR structure, 1997 (PDB 1BDD), downloaded from the RCSB Protein Data Bank.
Protein G (B1 domain) — Two crystal structures of the b1 immunoglobulin-binding domain of streptococcal protein g and comparison with nmr — X-ray structure, 1994 (PDB 1PGA), downloaded from the RCSB Protein Data Bank.
Streptavidin bound to biotin — Structural origins of high-affinity biotin binding to streptavidin — X-ray structure, 1992 (PDB 1STP), downloaded from the RCSB Protein Data Bank.
Avidin — Three-dimensional structure of the tetragonal crystal form of egg-white avidin in its functional complex with biotin at 2.7 angstroms res… — X-ray structure, 1994 (PDB 1AVD), downloaded from the RCSB Protein Data Bank.
Neonatal Fc receptor (FcRn) with Fc — Crystal structure of the neonatal fc receptor complexed with a heterodimeric fc — X-ray structure, 2001 (PDB 1I1A), downloaded from the RCSB Protein Data Bank.
IgG Fc fragment — Crystallographic refinement and atomic models of a human fc fragment and its complex with fragment b of protein a from staphylococcus aur… — X-ray structure, 1981 (PDB 1FC1), downloaded from the RCSB Protein Data Bank.
Antibody (intact IgG1 Mcg) — Three-dimensional structure of a human immunoglobulin with a hinge deletion — X-ray structure, 1994 (PDB 1MCO), downloaded from the RCSB Protein Data Bank.
IgM Fc pentamer with J chain — Cryo-em structure of human igm-fc in complex with the j chain and the ectodomain of pigr — cryo-EM structure, 2020 (PDB 6KXS), downloaded from the RCSB Protein Data Bank.
IgA Fc bound to staphylococcal SSL7 — Crystal structure of a staphylococcus aureus protein (ssl7) in complex with fc of human iga1 — X-ray structure, 2007 (PDB 2QEJ), downloaded from the RCSB Protein Data Bank.
DC-SIGN bound to oligosaccharide — Complex of dc-sign and glcnac2man3 — X-ray structure, 2001 (PDB 1K9I), downloaded from the RCSB Protein Data Bank.
Galectin-3 carbohydrate-binding domain — X-ray crystal structure of the human galectin-3 carbohydrate recognition domain (crd) at 2.1 angstrom resolution — X-ray structure, 1998 (PDB 1A3K), downloaded from the RCSB Protein Data Bank.
IgG1 Fc–FcγRIII complex — Crystal structure of soluble human igg1 fc fragment-fc-gamma receptor iii complex — X-ray structure, 2000 (PDB 1E4K), downloaded from the RCSB Protein Data Bank.
IgG1 Fc with FcγRIII — Crystal structure of a human type iii fc gamma receptor in complex with an fc fragment of igg1 (orthorhombic) — X-ray structure, 2004 (PDB 1T83), downloaded from the RCSB Protein Data Bank.
Antibody Fab (anti-factor IX) — Crystal structure of human factor ix gla domain in complex of an inhibitory antibody, 10c12 — X-ray structure, 2004 (PDB 1NL0), downloaded from the RCSB Protein Data Bank.
Pembrolizumab Fab bound to PD-1 — Pd-1 in complex with pembrolizumab fab — X-ray structure, 2016 (PDB 5GGS), downloaded from the RCSB Protein Data Bank.
PD-L1 bound to durvalumab Fab — Pd-l1 in complex with durvalumab — X-ray structure, 2017 (PDB 5X8M), downloaded from the RCSB Protein Data Bank.
Adalimumab-like Fab with TNF — Crystal structure of ipilimumab fab complexed with ctla-4 at 2.6a resolution — X-ray structure, 2020 (PDB 6RP8), downloaded from the RCSB Protein Data Bank.
Adalimumab Fab with TNF-α — Crystal structure of tnfalpha in complex with adalimumab fab fragment — X-ray structure, 2013 (PDB 3WD5), downloaded from the RCSB Protein Data Bank.
PD-1 bound to pembrolizumab Fab — Human pd-1 ectodomain complexed with pembrolizumab fab — X-ray structure, 2016 (PDB 5JXE), downloaded from the RCSB Protein Data Bank.
Nanobody bound to GFP — Structure of the gfp:gfp-nanobody complex at 2.8 a resolution in spacegroup p21212 — X-ray structure, 2010 (PDB 3OGO), downloaded from the RCSB Protein Data Bank.
Nanobody (camelid VHH) — Nanobody/vhh domain 7d12 in complex with domain iii of the extracellular region of egfr, ph 6.0 — X-ray structure, 2013 (PDB 4KRL), downloaded from the RCSB Protein Data Bank.
Camelid VHH bound to lysozyme — Crystal structure of a camel single-domain vh antibody fragment in complex with lysozyme — X-ray structure, 1997 (PDB 1MEL), downloaded from the RCSB Protein Data Bank.
β2-microglobulin — Structure of the beta2_microglobulin involved in amyloidogenesis — X-ray structure, 2011 (PDB 2X89), downloaded from the RCSB Protein Data Bank.
IgE Fc with FcεRI — Structure of the human ige-fc bound to its high affinity receptor fc(epsilon)ri(alpha) — X-ray structure, 2000 (PDB 1F6A), downloaded from the RCSB Protein Data Bank.
FcRn with Fc — Crystal structure of the complex of rat neonatal fc receptor with fc — X-ray structure, 1995 (PDB 1FRT), downloaded from the RCSB Protein Data Bank.
T-cell receptor 2C with MHC (H-2Kb) — Structure of the 2c/kb/dev8 complex — X-ray structure, 1998 (PDB 2CKB), downloaded from the RCSB Protein Data Bank.
T-cell receptor recognising a cancer epitope — Germline-governed recognition of a cancer epitope by an immunodominant human t cell receptor — X-ray structure, 2009 (PDB 3HG1), downloaded from the RCSB Protein Data Bank.
DARPin (designed ankyrin repeat protein) — Designed ankyrin repeat protein (darpin) ytrl-2 selected by directed evolution against lysozyme — X-ray structure, 2018 (PDB 5OOS), downloaded from the RCSB Protein Data Bank.
EGFR with antibody GC1118 — The complex structure of extracellular domain of egfr and gc1118a — X-ray structure, 2015 (PDB 4UV7), downloaded from the RCSB Protein Data Bank.
Streptavidin–biotin — Biotin-bound streptavidin — cryo-EM structure, 2019 (PDB 6J6J), downloaded from the RCSB Protein Data Bank.
Insulin peptide on HLA-DQ8 — Crystal structure of a human insulin peptide-hla-dq8 complex — X-ray structure, 2001 (PDB 1JK8), downloaded from the RCSB Protein Data Bank.
T-cell receptor 2B4 — Crystal structure of the 2b4 tcr — X-ray structure, 2011 (PDB 3QJF), downloaded from the RCSB Protein Data Bank.