Library › DNA & Proteins › Human proteins (AlphaFold) · Development: Wnt signalling

Human proteins (AlphaFold) · Development: Wnt signalling: 44 3D models

DNA, RNA, nucleic-acid drugs, gene editing, proteins and 300+ real PDB structures (real sizes 1–100 nm). Each one is a ready-made 3D model you can turn, recolour and place in a figure — open BioDiorama and type its name in the Library search.

Open the 3D Studio

Axin-2 (AXIN2) — Axin-2 — human protein (gene AXIN2, 843 amino acids, UniProt Q9Y2T1). AlphaFold-predicted 3D structure; by default coloured by model confidence (blue = very high, orange = very low, typical of disordered regions).
Catenin delta-2 (CTNND2) — Catenin delta-2 — human protein (gene CTNND2, 1225 amino acids, UniProt Q9UQB3). AlphaFold-predicted 3D structure; by default coloured by model confidence (blue = very high, orange = very low, typical of disordered regions).
Dapper homolog 1 (DACT1) — Dapper homolog 1 — human protein (gene DACT1, 836 amino acids, UniProt Q9NYF0). AlphaFold-predicted 3D structure; by default coloured by model confidence (blue = very high, orange = very low, typical of disordered regions).
Dickkopf-related protein 1 (DKK1) — Dickkopf-related protein 1 — human protein (gene DKK1, 266 amino acids, UniProt O94907). AlphaFold-predicted 3D structure; by default coloured by model confidence (blue = very high, orange = very low, typical of disordered regions).
Dickkopf-related protein 2 (DKK2) — Dickkopf-related protein 2 — human protein (gene DKK2, 259 amino acids, UniProt Q9UBU2). AlphaFold-predicted 3D structure; by default coloured by model confidence (blue = very high, orange = very low, typical of disordered regions).
Dickkopf-related protein 3 (DKK3) — Dickkopf-related protein 3 — human protein (gene DKK3, 350 amino acids, UniProt Q9UBP4). AlphaFold-predicted 3D structure; by default coloured by model confidence (blue = very high, orange = very low, typical of disordered regions).
Dickkopf-related protein 4 (DKK4) — Dickkopf-related protein 4 — human protein (gene DKK4, 224 amino acids, UniProt Q9UBT3). AlphaFold-predicted 3D structure; by default coloured by model confidence (blue = very high, orange = very low, typical of disordered regions).
Disrupted in schizophrenia 1 protein (DISC1) — Disrupted in schizophrenia 1 protein — human protein (gene DISC1, 854 amino acids, UniProt Q9NRI5). AlphaFold-predicted 3D structure; by default coloured by model confidence (blue = very high, orange = very low, typical of disordered regions).
Dixin (DIXDC1) — Dixin — human protein (gene DIXDC1, 683 amino acids, UniProt Q155Q3). AlphaFold-predicted 3D structure; by default coloured by model confidence (blue = very high, orange = very low, typical of disordered regions).
Draxin (DRAXIN) — Draxin — human protein (gene DRAXIN, 349 amino acids, UniProt Q8NBI3). AlphaFold-predicted 3D structure; by default coloured by model confidence (blue = very high, orange = very low, typical of disordered regions).
E3 ubiquitin-protein ligase ZNRF3 (ZNRF3) — E3 ubiquitin-protein ligase ZNRF3 — human protein (gene ZNRF3, 936 amino acids, UniProt Q9ULT6). AlphaFold-predicted 3D structure; by default coloured by model confidence (blue = very high, orange = very low, typical of disordered regions).
F-box/WD repeat-containing protein 4 (FBXW4) — F-box/WD repeat-containing protein 4 — human protein (gene FBXW4, 412 amino acids, UniProt P57775). AlphaFold-predicted 3D structure; by default coloured by model confidence (blue = very high, orange = very low, typical of disordered regions).
Frizzled-1 (FZD1) — Frizzled-1 — human protein (gene FZD1, 647 amino acids, UniProt Q9UP38). AlphaFold-predicted 3D structure; by default coloured by model confidence (blue = very high, orange = very low, typical of disordered regions).
Frizzled-10 (FZD10) — Frizzled-10 — human protein (gene FZD10, 581 amino acids, UniProt Q9ULW2). AlphaFold-predicted 3D structure; by default coloured by model confidence (blue = very high, orange = very low, typical of disordered regions).
Frizzled-3 (FZD3) — Frizzled-3 — human protein (gene FZD3, 666 amino acids, UniProt Q9NPG1). AlphaFold-predicted 3D structure; by default coloured by model confidence (blue = very high, orange = very low, typical of disordered regions).
Frizzled-4 (FZD4) — Frizzled-4 — human protein (gene FZD4, 537 amino acids, UniProt Q9ULV1). AlphaFold-predicted 3D structure; by default coloured by model confidence (blue = very high, orange = very low, typical of disordered regions).
Frizzled-8 (FZD8) — Frizzled-8 — human protein (gene FZD8, 694 amino acids, UniProt Q9H461). AlphaFold-predicted 3D structure; by default coloured by model confidence (blue = very high, orange = very low, typical of disordered regions).
Inversin (INVS) — Inversin — human protein (gene INVS, 1065 amino acids, UniProt Q9Y283). AlphaFold-predicted 3D structure; by default coloured by model confidence (blue = very high, orange = very low, typical of disordered regions).
Leucine-rich repeat-containing G protein-coupled receptor 4 (LGR4) — Leucine-rich repeat-containing G protein-coupled receptor 4 — human protein (gene LGR4, 951 amino acids, UniProt Q9BXB1). AlphaFold-predicted 3D structure; by default coloured by model confidence (blue = very high, orange = very low, typical of disordered regions).
Nucleoredoxin (NXN) — Nucleoredoxin — human protein (gene NXN, 435 amino acids, UniProt Q6DKJ4). AlphaFold-predicted 3D structure; by default coloured by model confidence (blue = very high, orange = very low, typical of disordered regions).
Protein CUSTOS (CUSTOS) — Protein CUSTOS — human protein (gene CUSTOS, 262 amino acids, UniProt Q96C57). AlphaFold-predicted 3D structure; by default coloured by model confidence (blue = very high, orange = very low, typical of disordered regions).
Protein Wnt-10a (WNT10A) — Protein Wnt-10a — human protein (gene WNT10A, 417 amino acids, UniProt Q9GZT5). AlphaFold-predicted 3D structure; by default coloured by model confidence (blue = very high, orange = very low, typical of disordered regions).
Protein Wnt-16 (WNT16) — Protein Wnt-16 — human protein (gene WNT16, 365 amino acids, UniProt Q9UBV4). AlphaFold-predicted 3D structure; by default coloured by model confidence (blue = very high, orange = very low, typical of disordered regions).
Protein Wnt-2b (WNT2B) — Protein Wnt-2b — human protein (gene WNT2B, 391 amino acids, UniProt Q93097). AlphaFold-predicted 3D structure; by default coloured by model confidence (blue = very high, orange = very low, typical of disordered regions).
Protein Wnt-5b (WNT5B) — Protein Wnt-5b — human protein (gene WNT5B, 359 amino acids, UniProt Q9H1J7). AlphaFold-predicted 3D structure; by default coloured by model confidence (blue = very high, orange = very low, typical of disordered regions).
Protein Wnt-6 (WNT6) — Protein Wnt-6 — human protein (gene WNT6, 365 amino acids, UniProt Q9Y6F9). AlphaFold-predicted 3D structure; by default coloured by model confidence (blue = very high, orange = very low, typical of disordered regions).
Protein Wnt-8a (WNT8A) — Protein Wnt-8a — human protein (gene WNT8A, 351 amino acids, UniProt Q9H1J5). AlphaFold-predicted 3D structure; by default coloured by model confidence (blue = very high, orange = very low, typical of disordered regions).
Protein Wnt-8b (WNT8B) — Protein Wnt-8b — human protein (gene WNT8B, 351 amino acids, UniProt Q93098). AlphaFold-predicted 3D structure; by default coloured by model confidence (blue = very high, orange = very low, typical of disordered regions).
Protein wntless homolog (WLS) — Protein wntless homolog — human protein (gene WLS, 541 amino acids, UniProt Q5T9L3). AlphaFold-predicted 3D structure; by default coloured by model confidence (blue = very high, orange = very low, typical of disordered regions).
Putative segment polarity protein dishevelled homolog DVL1P1 (DVL1P1) — Putative segment polarity protein dishevelled homolog DVL1P1 — human protein (gene DVL1P1, 670 amino acids, UniProt P54792). AlphaFold-predicted 3D structure; by default coloured by model confidence (blue = very high, orange = very low, typical of disordered regions).
R-spondin-2 (RSPO2) — R-spondin-2 — human protein (gene RSPO2, 243 amino acids, UniProt Q6UXX9). AlphaFold-predicted 3D structure; by default coloured by model confidence (blue = very high, orange = very low, typical of disordered regions).
Secreted frizzled-related protein 1 (SFRP1) — Secreted frizzled-related protein 1 — human protein (gene SFRP1, 314 amino acids, UniProt Q8N474). AlphaFold-predicted 3D structure; by default coloured by model confidence (blue = very high, orange = very low, typical of disordered regions).
Secreted frizzled-related protein 2 (SFRP2) — Secreted frizzled-related protein 2 — human protein (gene SFRP2, 295 amino acids, UniProt Q96HF1). AlphaFold-predicted 3D structure; by default coloured by model confidence (blue = very high, orange = very low, typical of disordered regions).
Secreted frizzled-related protein 3 (FRZB) — Secreted frizzled-related protein 3 — human protein (gene FRZB, 325 amino acids, UniProt Q92765). AlphaFold-predicted 3D structure; by default coloured by model confidence (blue = very high, orange = very low, typical of disordered regions).
Secreted frizzled-related protein 4 (SFRP4) — Secreted frizzled-related protein 4 — human protein (gene SFRP4, 346 amino acids, UniProt Q6FHJ7). AlphaFold-predicted 3D structure; by default coloured by model confidence (blue = very high, orange = very low, typical of disordered regions).
Secreted frizzled-related protein 5 (SFRP5) — Secreted frizzled-related protein 5 — human protein (gene SFRP5, 317 amino acids, UniProt Q5T4F7). AlphaFold-predicted 3D structure; by default coloured by model confidence (blue = very high, orange = very low, typical of disordered regions).
Segment polarity protein dishevelled homolog DVL-1 (DVL1) — Segment polarity protein dishevelled homolog DVL-1 — human protein (gene DVL1, 695 amino acids, UniProt O14640). AlphaFold-predicted 3D structure; by default coloured by model confidence (blue = very high, orange = very low, typical of disordered regions).
Segment polarity protein dishevelled homolog DVL-2 (DVL2) — Segment polarity protein dishevelled homolog DVL-2 — human protein (gene DVL2, 736 amino acids, UniProt O14641). AlphaFold-predicted 3D structure; by default coloured by model confidence (blue = very high, orange = very low, typical of disordered regions).
Segment polarity protein dishevelled homolog DVL-3 (DVL3) — Segment polarity protein dishevelled homolog DVL-3 — human protein (gene DVL3, 716 amino acids, UniProt Q92997). AlphaFold-predicted 3D structure; by default coloured by model confidence (blue = very high, orange = very low, typical of disordered regions).
Serine/threonine-protein kinase MARK2 (MARK2) — Serine/threonine-protein kinase MARK2 — human protein (gene MARK2, 788 amino acids, UniProt Q7KZI7). AlphaFold-predicted 3D structure; by default coloured by model confidence (blue = very high, orange = very low, typical of disordered regions).
Spindlin-1 (SPIN1) — Spindlin-1 — human protein (gene SPIN1, 262 amino acids, UniProt Q9Y657). AlphaFold-predicted 3D structure; by default coloured by model confidence (blue = very high, orange = very low, typical of disordered regions).
Transmembrane protein 198 (TMEM198) — Transmembrane protein 198 — human protein (gene TMEM198, 360 amino acids, UniProt Q66K66). AlphaFold-predicted 3D structure; by default coloured by model confidence (blue = very high, orange = very low, typical of disordered regions).
Transmembrane protein 88 (TMEM88) — Transmembrane protein 88 — human protein (gene TMEM88, 159 amino acids, UniProt Q6PEY1). AlphaFold-predicted 3D structure; by default coloured by model confidence (blue = very high, orange = very low, typical of disordered regions).
Wnt inhibitory factor 1 (WIF1) — Wnt inhibitory factor 1 — human protein (gene WIF1, 379 amino acids, UniProt Q9Y5W5). AlphaFold-predicted 3D structure; by default coloured by model confidence (blue = very high, orange = very low, typical of disordered regions).