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Human proteins (AlphaFold) · DNA repair & replication: 200 3D models

DNA, RNA, nucleic-acid drugs, gene editing, proteins and 300+ real PDB structures (real sizes 1–100 nm). Each one is a ready-made 3D model you can turn, recolour and place in a figure — open BioDioRama and type its name in the Library search.

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Structure-specific endonuclease subunit EME2 (EME2) — Structure-specific endonuclease subunit EME2 — human protein (gene EME2, 379 amino acids, UniProt A4GXA9). AlphaFold-predicted 3D structure; by default coloured by model confidence (blue = very high, orange = very low, typical of disordered regions).
Structural maintenance of chromosomes flexible hinge domain-containing protein 1 (SMCHD1) — Structural maintenance of chromosomes flexible hinge domain-containing protein 1 — human protein (gene SMCHD1, 2005 amino acids, UniProt A6NHR9). AlphaFold-predicted 3D structure; by default coloured by model confidence (blue = very high, orange = very low, typical of disordered regions).
Centromere protein X (CENPX) — Centromere protein X — human protein (gene CENPX, 81 amino acids, UniProt A8MT69). AlphaFold-predicted 3D structure; by default coloured by model confidence (blue = very high, orange = very low, typical of disordered regions).
Fanconi anemia group G protein (FANCG) — Fanconi anemia group G protein — human protein (gene FANCG, 622 amino acids, UniProt O15287). AlphaFold-predicted 3D structure; by default coloured by model confidence (blue = very high, orange = very low, typical of disordered regions).
DNA repair protein RAD51 homolog 2 (RAD51B) — DNA repair protein RAD51 homolog 2 — human protein (gene RAD51B, 384 amino acids, UniProt O15315). AlphaFold-predicted 3D structure; by default coloured by model confidence (blue = very high, orange = very low, typical of disordered regions).
Fanconi anemia group A protein (FANCA) — Fanconi anemia group A protein — human protein (gene FANCA, 1455 amino acids, UniProt O15360). AlphaFold-predicted 3D structure; by default coloured by model confidence (blue = very high, orange = very low, typical of disordered regions).
N-glycosylase/DNA lyase [Includes: 8-oxoguanine DNA glycosylase (OGG1) — N-glycosylase/DNA lyase [Includes: 8-oxoguanine DNA glycosylase — human protein (gene OGG1, 345 amino acids, UniProt O15527). AlphaFold-predicted 3D structure; by default coloured by model confidence (blue = very high, orange = very low, typical of disordered regions).
MutS protein homolog 5 (MSH5) — MutS protein homolog 5 — human protein (gene MSH5, 834 amino acids, UniProt O43196). AlphaFold-predicted 3D structure; by default coloured by model confidence (blue = very high, orange = very low, typical of disordered regions).
AP-5 complex subunit zeta-1 (AP5Z1) — AP-5 complex subunit zeta-1 — human protein (gene AP5Z1, 807 amino acids, UniProt O43299). AlphaFold-predicted 3D structure; by default coloured by model confidence (blue = very high, orange = very low, typical of disordered regions).
DNA repair protein RAD51 homolog 3 (RAD51C) — DNA repair protein RAD51 homolog 3 — human protein (gene RAD51C, 376 amino acids, UniProt O43502). AlphaFold-predicted 3D structure; by default coloured by model confidence (blue = very high, orange = very low, typical of disordered regions).
DNA repair protein XRCC3 (XRCC3) — DNA repair protein XRCC3 — human protein (gene XRCC3, 346 amino acids, UniProt O43542). AlphaFold-predicted 3D structure; by default coloured by model confidence (blue = very high, orange = very low, typical of disordered regions).
17S U2 SnRNP complex component HTATSF1 (HTATSF1) — 17S U2 SnRNP complex component HTATSF1 — human protein (gene HTATSF1, 755 amino acids, UniProt O43719). AlphaFold-predicted 3D structure; by default coloured by model confidence (blue = very high, orange = very low, typical of disordered regions).
Origin recognition complex subunit 5 (ORC5) — Origin recognition complex subunit 5 — human protein (gene ORC5, 435 amino acids, UniProt O43913). AlphaFold-predicted 3D structure; by default coloured by model confidence (blue = very high, orange = very low, typical of disordered regions).
Origin recognition complex subunit 4 (ORC4) — Origin recognition complex subunit 4 — human protein (gene ORC4, 436 amino acids, UniProt O43929). AlphaFold-predicted 3D structure; by default coloured by model confidence (blue = very high, orange = very low, typical of disordered regions).
Cell cycle checkpoint protein RAD1 (RAD1) — Cell cycle checkpoint protein RAD1 — human protein (gene RAD1, 282 amino acids, UniProt O60671). AlphaFold-predicted 3D structure; by default coloured by model confidence (blue = very high, orange = very low, typical of disordered regions).
DNA/RNA-binding protein KIN17 (KIN) — DNA/RNA-binding protein KIN17 — human protein (gene KIN, 393 amino acids, UniProt O60870). AlphaFold-predicted 3D structure; by default coloured by model confidence (blue = very high, orange = very low, typical of disordered regions).
Nibrin (NBN) — Nibrin — human protein (gene NBN, 754 amino acids, UniProt O60934). AlphaFold-predicted 3D structure; by default coloured by model confidence (blue = very high, orange = very low, typical of disordered regions).
DNA polymerase theta (POLQ) — DNA polymerase theta — human protein (gene POLQ, 2590 amino acids, UniProt O75417). AlphaFold-predicted 3D structure; by default coloured by model confidence (blue = very high, orange = very low, typical of disordered regions).
Cell division control protein 45 homolog (CDC45) — Cell division control protein 45 homolog — human protein (gene CDC45, 566 amino acids, UniProt O75419). AlphaFold-predicted 3D structure; by default coloured by model confidence (blue = very high, orange = very low, typical of disordered regions).
ATP-dependent DNA helicase Q5 (RECQL5) — ATP-dependent DNA helicase Q5 — human protein (gene RECQL5, 991 amino acids, UniProt O94762). AlphaFold-predicted 3D structure; by default coloured by model confidence (blue = very high, orange = very low, typical of disordered regions).
Methyl-CpG-binding domain protein 4 (MBD4) — Methyl-CpG-binding domain protein 4 — human protein (gene MBD4, 580 amino acids, UniProt O95243). AlphaFold-predicted 3D structure; by default coloured by model confidence (blue = very high, orange = very low, typical of disordered regions).
Histone acetyltransferase KAT7 (KAT7) — Histone acetyltransferase KAT7 — human protein (gene KAT7, 611 amino acids, UniProt O95251). AlphaFold-predicted 3D structure; by default coloured by model confidence (blue = very high, orange = very low, typical of disordered regions).
Tyrosyl-DNA phosphodiesterase 2 (TDP2) — Tyrosyl-DNA phosphodiesterase 2 — human protein (gene TDP2, 362 amino acids, UniProt O95551). AlphaFold-predicted 3D structure; by default coloured by model confidence (blue = very high, orange = very low, typical of disordered regions).
Securin (PTTG1) — Securin — human protein (gene PTTG1, 202 amino acids, UniProt O95997). AlphaFold-predicted 3D structure; by default coloured by model confidence (blue = very high, orange = very low, typical of disordered regions).
Actin-like protein 6A (ACTL6A) — Actin-like protein 6A — human protein (gene ACTL6A, 429 amino acids, UniProt O96019). AlphaFold-predicted 3D structure; by default coloured by model confidence (blue = very high, orange = very low, typical of disordered regions).
DNA polymerase beta (POLB) — DNA polymerase beta — human protein (gene POLB, 335 amino acids, UniProt P06746). AlphaFold-predicted 3D structure; by default coloured by model confidence (blue = very high, orange = very low, typical of disordered regions).
Fumarate hydratase, mitochondrial (FH) — Fumarate hydratase, mitochondrial — human protein (gene FH, 510 amino acids, UniProt P07954). AlphaFold-predicted 3D structure; by default coloured by model confidence (blue = very high, orange = very low, typical of disordered regions).
DNA excision repair protein ERCC-1 (ERCC1) — DNA excision repair protein ERCC-1 — human protein (gene ERCC1, 297 amino acids, UniProt P07992). AlphaFold-predicted 3D structure; by default coloured by model confidence (blue = very high, orange = very low, typical of disordered regions).
DNA polymerase alpha catalytic subunit (POLA1) — DNA polymerase alpha catalytic subunit — human protein (gene POLA1, 1462 amino acids, UniProt P09884). AlphaFold-predicted 3D structure; by default coloured by model confidence (blue = very high, orange = very low, typical of disordered regions).
TCF3 fusion partner (TFPT) — TCF3 fusion partner — human protein (gene TFPT, 253 amino acids, UniProt P0C1Z6). AlphaFold-predicted 3D structure; by default coloured by model confidence (blue = very high, orange = very low, typical of disordered regions).
DNA sliding clamp PCNA (PCNA) — DNA sliding clamp PCNA — human protein (gene PCNA, 261 amino acids, UniProt P12004). AlphaFold-predicted 3D structure; by default coloured by model confidence (blue = very high, orange = very low, typical of disordered regions).
Uracil-DNA glycosylase (UNG) — Uracil-DNA glycosylase — human protein (gene UNG, 313 amino acids, UniProt P13051). AlphaFold-predicted 3D structure; by default coloured by model confidence (blue = very high, orange = very low, typical of disordered regions).
Replication protein A 32 kDa subunit (RPA2) — Replication protein A 32 kDa subunit — human protein (gene RPA2, 270 amino acids, UniProt P15927). AlphaFold-predicted 3D structure; by default coloured by model confidence (blue = very high, orange = very low, typical of disordered regions).
Histone H2AX (H2AX) — Histone H2AX — human protein (gene H2AX, 143 amino acids, UniProt P16104). AlphaFold-predicted 3D structure; by default coloured by model confidence (blue = very high, orange = very low, typical of disordered regions).
Methylated-DNA--protein-cysteine methyltransferase (MGMT) — Methylated-DNA--protein-cysteine methyltransferase — human protein (gene MGMT, 207 amino acids, UniProt P16455). AlphaFold-predicted 3D structure; by default coloured by model confidence (blue = very high, orange = very low, typical of disordered regions).
DNA ligase 1 (LIG1) — DNA ligase 1 — human protein (gene LIG1, 919 amino acids, UniProt P18858). AlphaFold-predicted 3D structure; by default coloured by model confidence (blue = very high, orange = very low, typical of disordered regions).
DNA repair protein XRCC1 (XRCC1) — DNA repair protein XRCC1 — human protein (gene XRCC1, 633 amino acids, UniProt P18887). AlphaFold-predicted 3D structure; by default coloured by model confidence (blue = very high, orange = very low, typical of disordered regions).
DNA mismatch repair protein Msh3 (MSH3) — DNA mismatch repair protein Msh3 — human protein (gene MSH3, 1137 amino acids, UniProt P20585). AlphaFold-predicted 3D structure; by default coloured by model confidence (blue = very high, orange = very low, typical of disordered regions).
DNA repair protein complementing XP-A cells (XPA) — DNA repair protein complementing XP-A cells — human protein (gene XPA, 273 amino acids, UniProt P23025). AlphaFold-predicted 3D structure; by default coloured by model confidence (blue = very high, orange = very low, typical of disordered regions).
DNA replication licensing factor MCM3 (MCM3) — DNA replication licensing factor MCM3 — human protein (gene MCM3, 808 amino acids, UniProt P25205). AlphaFold-predicted 3D structure; by default coloured by model confidence (blue = very high, orange = very low, typical of disordered regions).
Replication protein A 70 kDa DNA-binding subunit (RPA1) — Replication protein A 70 kDa DNA-binding subunit — human protein (gene RPA1, 616 amino acids, UniProt P27694). AlphaFold-predicted 3D structure; by default coloured by model confidence (blue = very high, orange = very low, typical of disordered regions).
DNA polymerase delta catalytic subunit (POLD1) — DNA polymerase delta catalytic subunit — human protein (gene POLD1, 1107 amino acids, UniProt P28340). AlphaFold-predicted 3D structure; by default coloured by model confidence (blue = very high, orange = very low, typical of disordered regions).
DNA excision repair protein ERCC-5 (ERCC5) — DNA excision repair protein ERCC-5 — human protein (gene ERCC5, 1186 amino acids, UniProt P28715). AlphaFold-predicted 3D structure; by default coloured by model confidence (blue = very high, orange = very low, typical of disordered regions).
DNA-3-methyladenine glycosylase (MPG) — DNA-3-methyladenine glycosylase — human protein (gene MPG, 298 amino acids, UniProt P29372). AlphaFold-predicted 3D structure; by default coloured by model confidence (blue = very high, orange = very low, typical of disordered regions).
RNA-binding motif, single-stranded-interacting protein 1 (RBMS1) — RNA-binding motif, single-stranded-interacting protein 1 — human protein (gene RBMS1, 406 amino acids, UniProt P29558). AlphaFold-predicted 3D structure; by default coloured by model confidence (blue = very high, orange = very low, typical of disordered regions).
General transcription factor IIH subunit 1 (GTF2H1) — General transcription factor IIH subunit 1 — human protein (gene GTF2H1, 548 amino acids, UniProt P32780). AlphaFold-predicted 3D structure; by default coloured by model confidence (blue = very high, orange = very low, typical of disordered regions).
DNA replication licensing factor MCM4 (MCM4) — DNA replication licensing factor MCM4 — human protein (gene MCM4, 863 amino acids, UniProt P33991). AlphaFold-predicted 3D structure; by default coloured by model confidence (blue = very high, orange = very low, typical of disordered regions).
DNA replication licensing factor MCM5 (MCM5) — DNA replication licensing factor MCM5 — human protein (gene MCM5, 734 amino acids, UniProt P33992). AlphaFold-predicted 3D structure; by default coloured by model confidence (blue = very high, orange = very low, typical of disordered regions).
DNA replication licensing factor MCM7 (MCM7) — DNA replication licensing factor MCM7 — human protein (gene MCM7, 719 amino acids, UniProt P33993). AlphaFold-predicted 3D structure; by default coloured by model confidence (blue = very high, orange = very low, typical of disordered regions).
Replication protein A 14 kDa subunit (RPA3) — Replication protein A 14 kDa subunit — human protein (gene RPA3, 121 amino acids, UniProt P35244). AlphaFold-predicted 3D structure; by default coloured by model confidence (blue = very high, orange = very low, typical of disordered regions).
Replication factor C subunit 4 (RFC4) — Replication factor C subunit 4 — human protein (gene RFC4, 363 amino acids, UniProt P35249). AlphaFold-predicted 3D structure; by default coloured by model confidence (blue = very high, orange = very low, typical of disordered regions).
Replication factor C subunit 2 (RFC2) — Replication factor C subunit 2 — human protein (gene RFC2, 354 amino acids, UniProt P35250). AlphaFold-predicted 3D structure; by default coloured by model confidence (blue = very high, orange = very low, typical of disordered regions).
Replication factor C subunit 1 (RFC1) — Replication factor C subunit 1 — human protein (gene RFC1, 1148 amino acids, UniProt P35251). AlphaFold-predicted 3D structure; by default coloured by model confidence (blue = very high, orange = very low, typical of disordered regions).
Flap endonuclease 1 (FEN1) — Flap endonuclease 1 — human protein (gene FEN1, 380 amino acids, UniProt P39748). AlphaFold-predicted 3D structure; by default coloured by model confidence (blue = very high, orange = very low, typical of disordered regions).
DNA mismatch repair protein Mlh1 (MLH1) — DNA mismatch repair protein Mlh1 — human protein (gene MLH1, 756 amino acids, UniProt P40692). AlphaFold-predicted 3D structure; by default coloured by model confidence (blue = very high, orange = very low, typical of disordered regions).
Replication factor C subunit 5 (RFC5) — Replication factor C subunit 5 — human protein (gene RFC5, 340 amino acids, UniProt P40937). AlphaFold-predicted 3D structure; by default coloured by model confidence (blue = very high, orange = very low, typical of disordered regions).
Replication factor C subunit 3 (RFC3) — Replication factor C subunit 3 — human protein (gene RFC3, 356 amino acids, UniProt P40938). AlphaFold-predicted 3D structure; by default coloured by model confidence (blue = very high, orange = very low, typical of disordered regions).
Centrin-2 (CETN2) — Centrin-2 — human protein (gene CETN2, 172 amino acids, UniProt P41208). AlphaFold-predicted 3D structure; by default coloured by model confidence (blue = very high, orange = very low, typical of disordered regions).
DNA mismatch repair protein Msh2 (MSH2) — DNA mismatch repair protein Msh2 — human protein (gene MSH2, 934 amino acids, UniProt P43246). AlphaFold-predicted 3D structure; by default coloured by model confidence (blue = very high, orange = very low, typical of disordered regions).
DNA repair protein RAD52 homolog (RAD52) — DNA repair protein RAD52 homolog — human protein (gene RAD52, 418 amino acids, UniProt P43351). AlphaFold-predicted 3D structure; by default coloured by model confidence (blue = very high, orange = very low, typical of disordered regions).
Chromatin remodeler ATRX (ATRX) — Chromatin remodeler ATRX — human protein (gene ATRX, 2492 amino acids, UniProt P46100). AlphaFold-predicted 3D structure; by default coloured by model confidence (blue = very high, orange = very low, typical of disordered regions).
DNA polymerase delta subunit 2 (POLD2) — DNA polymerase delta subunit 2 — human protein (gene POLD2, 469 amino acids, UniProt P49005). AlphaFold-predicted 3D structure; by default coloured by model confidence (blue = very high, orange = very low, typical of disordered regions).
Nuclear autoantigenic sperm protein (NASP) — Nuclear autoantigenic sperm protein — human protein (gene NASP, 788 amino acids, UniProt P49321). AlphaFold-predicted 3D structure; by default coloured by model confidence (blue = very high, orange = very low, typical of disordered regions).
DNA primase small subunit (PRIM1) — DNA primase small subunit — human protein (gene PRIM1, 420 amino acids, UniProt P49642). AlphaFold-predicted 3D structure; by default coloured by model confidence (blue = very high, orange = very low, typical of disordered regions).
DNA primase large subunit (PRIM2) — DNA primase large subunit — human protein (gene PRIM2, 509 amino acids, UniProt P49643). AlphaFold-predicted 3D structure; by default coloured by model confidence (blue = very high, orange = very low, typical of disordered regions).
DNA replication licensing factor MCM2 (MCM2) — DNA replication licensing factor MCM2 — human protein (gene MCM2, 904 amino acids, UniProt P49736). AlphaFold-predicted 3D structure; by default coloured by model confidence (blue = very high, orange = very low, typical of disordered regions).
Winged helix repair factor 1 (WHR1) — Winged helix repair factor 1 — human protein (gene WHR1, 254 amino acids, UniProt P49842). AlphaFold-predicted 3D structure; by default coloured by model confidence (blue = very high, orange = very low, typical of disordered regions).
DNA ligase 3 (LIG3) — DNA ligase 3 — human protein (gene LIG3, 1009 amino acids, UniProt P49916). AlphaFold-predicted 3D structure; by default coloured by model confidence (blue = very high, orange = very low, typical of disordered regions).
DNA ligase 4 (LIG4) — DNA ligase 4 — human protein (gene LIG4, 911 amino acids, UniProt P49917). AlphaFold-predicted 3D structure; by default coloured by model confidence (blue = very high, orange = very low, typical of disordered regions).
Double-strand break repair protein MRE11 (MRE11) — Double-strand break repair protein MRE11 — human protein (gene MRE11, 708 amino acids, UniProt P49959). AlphaFold-predicted 3D structure; by default coloured by model confidence (blue = very high, orange = very low, typical of disordered regions).
DNA replication ATP-dependent helicase/nuclease DNA2 (DNA2) — DNA replication ATP-dependent helicase/nuclease DNA2 — human protein (gene DNA2, 1060 amino acids, UniProt P51530). AlphaFold-predicted 3D structure; by default coloured by model confidence (blue = very high, orange = very low, typical of disordered regions).
DNA mismatch repair protein Msh6 (MSH6) — DNA mismatch repair protein Msh6 — human protein (gene MSH6, 1360 amino acids, UniProt P52701). AlphaFold-predicted 3D structure; by default coloured by model confidence (blue = very high, orange = very low, typical of disordered regions).
DNA polymerase subunit gamma-1 (POLG) — DNA polymerase subunit gamma-1 — human protein (gene POLG, 1239 amino acids, UniProt P54098). AlphaFold-predicted 3D structure; by default coloured by model confidence (blue = very high, orange = very low, typical of disordered regions).
RecQ-like DNA helicase BLM (BLM) — RecQ-like DNA helicase BLM — human protein (gene BLM, 1417 amino acids, UniProt P54132). AlphaFold-predicted 3D structure; by default coloured by model confidence (blue = very high, orange = very low, typical of disordered regions).
PMS1 protein homolog 1 (PMS1) — PMS1 protein homolog 1 — human protein (gene PMS1, 932 amino acids, UniProt P54277). AlphaFold-predicted 3D structure; by default coloured by model confidence (blue = very high, orange = very low, typical of disordered regions).
Mismatch repair endonuclease PMS2 (PMS2) — Mismatch repair endonuclease PMS2 — human protein (gene PMS2, 862 amino acids, UniProt P54278). AlphaFold-predicted 3D structure; by default coloured by model confidence (blue = very high, orange = very low, typical of disordered regions).
Lysine-specific demethylase RAD23A (RAD23A) — Lysine-specific demethylase RAD23A — human protein (gene RAD23A, 363 amino acids, UniProt P54725). AlphaFold-predicted 3D structure; by default coloured by model confidence (blue = very high, orange = very low, typical of disordered regions).
DNA polymerase epsilon subunit 2 (POLE2) — DNA polymerase epsilon subunit 2 — human protein (gene POLE2, 527 amino acids, UniProt P56282). AlphaFold-predicted 3D structure; by default coloured by model confidence (blue = very high, orange = very low, typical of disordered regions).
Transcription elongation factor 1 homolog (ELOF1) — Transcription elongation factor 1 homolog — human protein (gene ELOF1, 83 amino acids, UniProt P60002). AlphaFold-predicted 3D structure; by default coloured by model confidence (blue = very high, orange = very low, typical of disordered regions).
Endonuclease III-like protein 1 (NTHL1) — Endonuclease III-like protein 1 — human protein (gene NTHL1, 304 amino acids, UniProt P78549). AlphaFold-predicted 3D structure; by default coloured by model confidence (blue = very high, orange = very low, typical of disordered regions).
Fanconi anemia group C protein (FANCC) — Fanconi anemia group C protein — human protein (gene FANCC, 558 amino acids, UniProt Q00597). AlphaFold-predicted 3D structure; by default coloured by model confidence (blue = very high, orange = very low, typical of disordered regions).
Heat shock factor protein 1 (HSF1) — Heat shock factor protein 1 — human protein (gene HSF1, 529 amino acids, UniProt Q00613). AlphaFold-predicted 3D structure; by default coloured by model confidence (blue = very high, orange = very low, typical of disordered regions).
Exosome complex component 10 (EXOSC10) — Exosome complex component 10 — human protein (gene EXOSC10, 885 amino acids, UniProt Q01780). AlphaFold-predicted 3D structure; by default coloured by model confidence (blue = very high, orange = very low, typical of disordered regions).
DNA repair protein complementing XP-C cells (XPC) — DNA repair protein complementing XP-C cells — human protein (gene XPC, 940 amino acids, UniProt Q01831). AlphaFold-predicted 3D structure; by default coloured by model confidence (blue = very high, orange = very low, typical of disordered regions).
DNA excision repair protein ERCC-6 (ERCC6) — DNA excision repair protein ERCC-6 — human protein (gene ERCC6, 1493 amino acids, UniProt Q03468). AlphaFold-predicted 3D structure; by default coloured by model confidence (blue = very high, orange = very low, typical of disordered regions).
Single-stranded DNA-binding protein, mitochondrial (SSBP1) — Single-stranded DNA-binding protein, mitochondrial — human protein (gene SSBP1, 148 amino acids, UniProt Q04837). AlphaFold-predicted 3D structure; by default coloured by model confidence (blue = very high, orange = very low, typical of disordered regions).
DNA repair protein RAD51 homolog 1 (RAD51) — DNA repair protein RAD51 homolog 1 — human protein (gene RAD51, 339 amino acids, UniProt Q06609). AlphaFold-predicted 3D structure; by default coloured by model confidence (blue = very high, orange = very low, typical of disordered regions).
DNA polymerase epsilon catalytic subunit A (POLE) — DNA polymerase epsilon catalytic subunit A — human protein (gene POLE, 2286 amino acids, UniProt Q07864). AlphaFold-predicted 3D structure; by default coloured by model confidence (blue = very high, orange = very low, typical of disordered regions).
Forkhead box protein M1 (FOXM1) — Forkhead box protein M1 — human protein (gene FOXM1, 763 amino acids, UniProt Q08050). AlphaFold-predicted 3D structure; by default coloured by model confidence (blue = very high, orange = very low, typical of disordered regions).
ATP-dependent RNA helicase A (DHX9) — ATP-dependent RNA helicase A — human protein (gene DHX9, 1270 amino acids, UniProt Q08211). AlphaFold-predicted 3D structure; by default coloured by model confidence (blue = very high, orange = very low, typical of disordered regions).
FACT complex subunit SSRP1 (SSRP1) — FACT complex subunit SSRP1 — human protein (gene SSRP1, 709 amino acids, UniProt Q08945). AlphaFold-predicted 3D structure; by default coloured by model confidence (blue = very high, orange = very low, typical of disordered regions).
Fanconi anemia core complex-associated protein 100 (FAAP100) — Fanconi anemia core complex-associated protein 100 — human protein (gene FAAP100, 881 amino acids, UniProt Q0VG06). AlphaFold-predicted 3D structure; by default coloured by model confidence (blue = very high, orange = very low, typical of disordered regions).
Nuclear factor 1 A-type (NFIA) — Nuclear factor 1 A-type — human protein (gene NFIA, 509 amino acids, UniProt Q12857). AlphaFold-predicted 3D structure; by default coloured by model confidence (blue = very high, orange = very low, typical of disordered regions).
TP53-binding protein 1 (TP53BP1) — TP53-binding protein 1 — human protein (gene TP53BP1, 1972 amino acids, UniProt Q12888). AlphaFold-predicted 3D structure; by default coloured by model confidence (blue = very high, orange = very low, typical of disordered regions).
Replication protein A 30 kDa subunit (RPA4) — Replication protein A 30 kDa subunit — human protein (gene RPA4, 261 amino acids, UniProt Q13156). AlphaFold-predicted 3D structure; by default coloured by model confidence (blue = very high, orange = very low, typical of disordered regions).
Origin recognition complex subunit 1 (ORC1) — Origin recognition complex subunit 1 — human protein (gene ORC1, 861 amino acids, UniProt Q13415). AlphaFold-predicted 3D structure; by default coloured by model confidence (blue = very high, orange = very low, typical of disordered regions).
Origin recognition complex subunit 2 (ORC2) — Origin recognition complex subunit 2 — human protein (gene ORC2, 577 amino acids, UniProt Q13416). AlphaFold-predicted 3D structure; by default coloured by model confidence (blue = very high, orange = very low, typical of disordered regions).
DNA repair protein XRCC4 (XRCC4) — DNA repair protein XRCC4 — human protein (gene XRCC4, 336 amino acids, UniProt Q13426). AlphaFold-predicted 3D structure; by default coloured by model confidence (blue = very high, orange = very low, typical of disordered regions).
Serine/threonine-protein kinase ATR (ATR) — Serine/threonine-protein kinase ATR — human protein (gene ATR, 2644 amino acids, UniProt Q13535). AlphaFold-predicted 3D structure; by default coloured by model confidence (blue = very high, orange = very low, typical of disordered regions).
G/T mismatch-specific thymine DNA glycosylase (TDG) — G/T mismatch-specific thymine DNA glycosylase — human protein (gene TDG, 410 amino acids, UniProt Q13569). AlphaFold-predicted 3D structure; by default coloured by model confidence (blue = very high, orange = very low, typical of disordered regions).
Nucleic acid dioxygenase ALKBH1 (ALKBH1) — Nucleic acid dioxygenase ALKBH1 — human protein (gene ALKBH1, 389 amino acids, UniProt Q13686). AlphaFold-predicted 3D structure; by default coloured by model confidence (blue = very high, orange = very low, typical of disordered regions).
General transcription factor IIH subunit 2 (GTF2H2) — General transcription factor IIH subunit 2 — human protein (gene GTF2H2, 395 amino acids, UniProt Q13888). AlphaFold-predicted 3D structure; by default coloured by model confidence (blue = very high, orange = very low, typical of disordered regions).
General transcription factor IIH subunit 3 (GTF2H3) — General transcription factor IIH subunit 3 — human protein (gene GTF2H3, 308 amino acids, UniProt Q13889). AlphaFold-predicted 3D structure; by default coloured by model confidence (blue = very high, orange = very low, typical of disordered regions).
DNA repair-scaffolding protein (SPIDR) — DNA repair-scaffolding protein — human protein (gene SPIDR, 915 amino acids, UniProt Q14159). AlphaFold-predicted 3D structure; by default coloured by model confidence (blue = very high, orange = very low, typical of disordered regions).
DNA polymerase alpha subunit B (POLA2) — DNA polymerase alpha subunit B — human protein (gene POLA2, 598 amino acids, UniProt Q14181). AlphaFold-predicted 3D structure; by default coloured by model confidence (blue = very high, orange = very low, typical of disordered regions).
Bifunctional 3'-5' exonuclease/ATP-dependent helicase WRN (WRN) — Bifunctional 3'-5' exonuclease/ATP-dependent helicase WRN — human protein (gene WRN, 1432 amino acids, UniProt Q14191). AlphaFold-predicted 3D structure; by default coloured by model confidence (blue = very high, orange = very low, typical of disordered regions).
DNA replication licensing factor MCM6 (MCM6) — DNA replication licensing factor MCM6 — human protein (gene MCM6, 821 amino acids, UniProt Q14566). AlphaFold-predicted 3D structure; by default coloured by model confidence (blue = very high, orange = very low, typical of disordered regions).
Mediator of DNA damage checkpoint protein 1 (MDC1) — Mediator of DNA damage checkpoint protein 1 — human protein (gene MDC1, 2089 amino acids, UniProt Q14676). AlphaFold-predicted 3D structure; by default coloured by model confidence (blue = very high, orange = very low, typical of disordered regions).
Structural maintenance of chromosomes protein 1A (SMC1A) — Structural maintenance of chromosomes protein 1A — human protein (gene SMC1A, 1233 amino acids, UniProt Q14683). AlphaFold-predicted 3D structure; by default coloured by model confidence (blue = very high, orange = very low, typical of disordered regions).
DNA replication complex GINS protein PSF1 (GINS1) — DNA replication complex GINS protein PSF1 — human protein (gene GINS1, 196 amino acids, UniProt Q14691). AlphaFold-predicted 3D structure; by default coloured by model confidence (blue = very high, orange = very low, typical of disordered regions).
Nuclear factor 1 X-type (NFIX) — Nuclear factor 1 X-type — human protein (gene NFIX, 502 amino acids, UniProt Q14938). AlphaFold-predicted 3D structure; by default coloured by model confidence (blue = very high, orange = very low, typical of disordered regions).
Proteasome activator complex subunit 4 (PSME4) — Proteasome activator complex subunit 4 — human protein (gene PSME4, 1843 amino acids, UniProt Q14997). AlphaFold-predicted 3D structure; by default coloured by model confidence (blue = very high, orange = very low, typical of disordered regions).
PCNA-associated factor (PCLAF) — PCNA-associated factor — human protein (gene PCLAF, 111 amino acids, UniProt Q15004). AlphaFold-predicted 3D structure; by default coloured by model confidence (blue = very high, orange = very low, typical of disordered regions).
Mortality factor 4-like protein 2 (MORF4L2) — Mortality factor 4-like protein 2 — human protein (gene MORF4L2, 288 amino acids, UniProt Q15014). AlphaFold-predicted 3D structure; by default coloured by model confidence (blue = very high, orange = very low, typical of disordered regions).
DNA polymerase delta subunit 3 (POLD3) — DNA polymerase delta subunit 3 — human protein (gene POLD3, 466 amino acids, UniProt Q15054). AlphaFold-predicted 3D structure; by default coloured by model confidence (blue = very high, orange = very low, typical of disordered regions).
Advanced glycation end product-specific receptor (AGER) — Advanced glycation end product-specific receptor — human protein (gene AGER, 404 amino acids, UniProt Q15109). AlphaFold-predicted 3D structure; by default coloured by model confidence (blue = very high, orange = very low, typical of disordered regions).
Non-POU domain-containing octamer-binding protein (NONO) — Non-POU domain-containing octamer-binding protein — human protein (gene NONO, 471 amino acids, UniProt Q15233). AlphaFold-predicted 3D structure; by default coloured by model confidence (blue = very high, orange = very low, typical of disordered regions).
Flap endonuclease GEN homolog 1 (GEN1) — Flap endonuclease GEN homolog 1 — human protein (gene GEN1, 908 amino acids, UniProt Q17RS7). AlphaFold-predicted 3D structure; by default coloured by model confidence (blue = very high, orange = very low, typical of disordered regions).
Zinc finger SWIM domain-containing protein 7 (ZSWIM7) — Zinc finger SWIM domain-containing protein 7 — human protein (gene ZSWIM7, 140 amino acids, UniProt Q19AV6). AlphaFold-predicted 3D structure; by default coloured by model confidence (blue = very high, orange = very low, typical of disordered regions).
PWWP domain-containing DNA repair factor 3A (PWWP3A) — PWWP domain-containing DNA repair factor 3A — human protein (gene PWWP3A, 710 amino acids, UniProt Q2TAK8). AlphaFold-predicted 3D structure; by default coloured by model confidence (blue = very high, orange = very low, typical of disordered regions).
UV-stimulated scaffold protein A (UVSSA) — UV-stimulated scaffold protein A — human protein (gene UVSSA, 709 amino acids, UniProt Q2YD98). AlphaFold-predicted 3D structure; by default coloured by model confidence (blue = very high, orange = very low, typical of disordered regions).
Protein mono-ADP-ribosyltransferase PARP10 (PARP10) — Protein mono-ADP-ribosyltransferase PARP10 — human protein (gene PARP10, 1025 amino acids, UniProt Q53GL7). AlphaFold-predicted 3D structure; by default coloured by model confidence (blue = very high, orange = very low, typical of disordered regions).
Histone-lysine N-methyltransferase SETMAR (SETMAR) — Histone-lysine N-methyltransferase SETMAR — human protein (gene SETMAR, 684 amino acids, UniProt Q53H47). AlphaFold-predicted 3D structure; by default coloured by model confidence (blue = very high, orange = very low, typical of disordered regions).
Single-strand selective monofunctional uracil DNA glycosylase (SMUG1) — Single-strand selective monofunctional uracil DNA glycosylase — human protein (gene SMUG1, 270 amino acids, UniProt Q53HV7). AlphaFold-predicted 3D structure; by default coloured by model confidence (blue = very high, orange = very low, typical of disordered regions).
INO80 complex subunit D (INO80D) — INO80 complex subunit D — human protein (gene INO80D, 1027 amino acids, UniProt Q53TQ3). AlphaFold-predicted 3D structure; by default coloured by model confidence (blue = very high, orange = very low, typical of disordered regions).
DNA annealing helicase and endonuclease ZRANB3 (ZRANB3) — DNA annealing helicase and endonuclease ZRANB3 — human protein (gene ZRANB3, 1079 amino acids, UniProt Q5FWF4). AlphaFold-predicted 3D structure; by default coloured by model confidence (blue = very high, orange = very low, typical of disordered regions).
DNA excision repair protein ERCC-6-like 2 (ERCC6L2) — DNA excision repair protein ERCC-6-like 2 — human protein (gene ERCC6L2, 1561 amino acids, UniProt Q5T890). AlphaFold-predicted 3D structure; by default coloured by model confidence (blue = very high, orange = very low, typical of disordered regions).
Telomere-associated protein RIF1 (RIF1) — Telomere-associated protein RIF1 — human protein (gene RIF1, 2472 amino acids, UniProt Q5UIP0). AlphaFold-predicted 3D structure; by default coloured by model confidence (blue = very high, orange = very low, typical of disordered regions).
Zinc finger FYVE domain-containing protein 26 (ZFYVE26) — Zinc finger FYVE domain-containing protein 26 — human protein (gene ZFYVE26, 2539 amino acids, UniProt Q68DK2). AlphaFold-predicted 3D structure; by default coloured by model confidence (blue = very high, orange = very low, typical of disordered regions).
Integrator complex subunit 3 (INTS3) — Integrator complex subunit 3 — human protein (gene INTS3, 1043 amino acids, UniProt Q68E01). AlphaFold-predicted 3D structure; by default coloured by model confidence (blue = very high, orange = very low, typical of disordered regions).
Splicing regulator SDE2 (SDE2) — Splicing regulator SDE2 — human protein (gene SDE2, 451 amino acids, UniProt Q6IQ49). AlphaFold-predicted 3D structure; by default coloured by model confidence (blue = very high, orange = very low, typical of disordered regions).
DNA oxidative demethylase ALKBH2 (ALKBH2) — DNA oxidative demethylase ALKBH2 — human protein (gene ALKBH2, 261 amino acids, UniProt Q6NS38). AlphaFold-predicted 3D structure; by default coloured by model confidence (blue = very high, orange = very low, typical of disordered regions).
MRN complex-interacting protein (MRNIP) — MRN complex-interacting protein — human protein (gene MRNIP, 343 amino acids, UniProt Q6NTE8). AlphaFold-predicted 3D structure; by default coloured by model confidence (blue = very high, orange = very low, typical of disordered regions).
ATPase SWSAP1 (SWSAP1) — ATPase SWSAP1 — human protein (gene SWSAP1, 250 amino acids, UniProt Q6NVH7). AlphaFold-predicted 3D structure; by default coloured by model confidence (blue = very high, orange = very low, typical of disordered regions).
Fanconi anemia core complex-associated protein 20 (FAAP20) — Fanconi anemia core complex-associated protein 20 — human protein (gene FAAP20, 180 amino acids, UniProt Q6NZ36). AlphaFold-predicted 3D structure; by default coloured by model confidence (blue = very high, orange = very low, typical of disordered regions).
Nuclear factor related to kappa-B-binding protein (NFRKB) — Nuclear factor related to kappa-B-binding protein — human protein (gene NFRKB, 1299 amino acids, UniProt Q6P4R8). AlphaFold-predicted 3D structure; by default coloured by model confidence (blue = very high, orange = very low, typical of disordered regions).
INO80 complex subunit C (INO80C) — INO80 complex subunit C — human protein (gene INO80C, 192 amino acids, UniProt Q6PI98). AlphaFold-predicted 3D structure; by default coloured by model confidence (blue = very high, orange = very low, typical of disordered regions).
Fidgetin-like protein 1 (FIGNL1) — Fidgetin-like protein 1 — human protein (gene FIGNL1, 674 amino acids, UniProt Q6PIW4). AlphaFold-predicted 3D structure; by default coloured by model confidence (blue = very high, orange = very low, typical of disordered regions).
DNA cross-link repair 1A protein (DCLRE1A) — DNA cross-link repair 1A protein — human protein (gene DCLRE1A, 1040 amino acids, UniProt Q6PJP8). AlphaFold-predicted 3D structure; by default coloured by model confidence (blue = very high, orange = very low, typical of disordered regions).
BRCA1-A complex subunit Abraxas 1 (ABRAXAS1) — BRCA1-A complex subunit Abraxas 1 — human protein (gene ABRAXAS1, 409 amino acids, UniProt Q6UWZ7). AlphaFold-predicted 3D structure; by default coloured by model confidence (blue = very high, orange = very low, typical of disordered regions).
Shieldin complex subunit 3 (SHLD3) — Shieldin complex subunit 3 — human protein (gene SHLD3, 250 amino acids, UniProt Q6ZNX1). AlphaFold-predicted 3D structure; by default coloured by model confidence (blue = very high, orange = very low, typical of disordered regions).
Protein MMS22-like (MMS22L) — Protein MMS22-like — human protein (gene MMS22L, 1243 amino acids, UniProt Q6ZRQ5). AlphaFold-predicted 3D structure; by default coloured by model confidence (blue = very high, orange = very low, typical of disordered regions).
PAX-interacting protein 1 (PAXIP1) — PAX-interacting protein 1 — human protein (gene PAXIP1, 1069 amino acids, UniProt Q6ZW49). AlphaFold-predicted 3D structure; by default coloured by model confidence (blue = very high, orange = very low, typical of disordered regions).
General transcription factor IIH subunit 5 (GTF2H5) — General transcription factor IIH subunit 5 — human protein (gene GTF2H5, 71 amino acids, UniProt Q6ZYL4). AlphaFold-predicted 3D structure; by default coloured by model confidence (blue = very high, orange = very low, typical of disordered regions).
Protein MCM10 homolog (MCM10) — Protein MCM10 homolog — human protein (gene MCM10, 875 amino acids, UniProt Q7L590). AlphaFold-predicted 3D structure; by default coloured by model confidence (blue = very high, orange = very low, typical of disordered regions).
Serine/threonine-protein kinase TAO1 (TAOK1) — Serine/threonine-protein kinase TAO1 — human protein (gene TAOK1, 1001 amino acids, UniProt Q7L7X3). AlphaFold-predicted 3D structure; by default coloured by model confidence (blue = very high, orange = very low, typical of disordered regions).
Ribonucleoside-diphosphate reductase subunit M2 B (RRM2B) — Ribonucleoside-diphosphate reductase subunit M2 B — human protein (gene RRM2B, 351 amino acids, UniProt Q7LG56). AlphaFold-predicted 3D structure; by default coloured by model confidence (blue = very high, orange = very low, typical of disordered regions).
Aprataxin (APTX) — Aprataxin — human protein (gene APTX, 356 amino acids, UniProt Q7Z2E3). AlphaFold-predicted 3D structure; by default coloured by model confidence (blue = very high, orange = very low, typical of disordered regions).
Treslin (TICRR) — Treslin — human protein (gene TICRR, 1910 amino acids, UniProt Q7Z2Z1). AlphaFold-predicted 3D structure; by default coloured by model confidence (blue = very high, orange = very low, typical of disordered regions).
Helicase senataxin (SETX) — Helicase senataxin — human protein (gene SETX, 2677 amino acids, UniProt Q7Z333). AlphaFold-predicted 3D structure; by default coloured by model confidence (blue = very high, orange = very low, typical of disordered regions).
Pogo transposable element with ZNF domain (POGZ) — Pogo transposable element with ZNF domain — human protein (gene POGZ, 1410 amino acids, UniProt Q7Z3K3). AlphaFold-predicted 3D structure; by default coloured by model confidence (blue = very high, orange = very low, typical of disordered regions).
Hepatoma-derived growth factor-related protein 2 (HDGFL2) — Hepatoma-derived growth factor-related protein 2 — human protein (gene HDGFL2, 671 amino acids, UniProt Q7Z4V5). AlphaFold-predicted 3D structure; by default coloured by model confidence (blue = very high, orange = very low, typical of disordered regions).
BRCA2-interacting transcriptional repressor EMSY (EMSY) — BRCA2-interacting transcriptional repressor EMSY — human protein (gene EMSY, 1322 amino acids, UniProt Q7Z589). AlphaFold-predicted 3D structure; by default coloured by model confidence (blue = very high, orange = very low, typical of disordered regions).
DNA polymerase nu (POLN) — DNA polymerase nu — human protein (gene POLN, 900 amino acids, UniProt Q7Z5Q5). AlphaFold-predicted 3D structure; by default coloured by model confidence (blue = very high, orange = very low, typical of disordered regions).
E3 ubiquitin-protein ligase RBBP6 (RBBP6) — E3 ubiquitin-protein ligase RBBP6 — human protein (gene RBBP6, 1792 amino acids, UniProt Q7Z6E9). AlphaFold-predicted 3D structure; by default coloured by model confidence (blue = very high, orange = very low, typical of disordered regions).
Stimulated by retinoic acid gene 8 protein homolog (STRA8) — Stimulated by retinoic acid gene 8 protein homolog — human protein (gene STRA8, 330 amino acids, UniProt Q7Z7C7). AlphaFold-predicted 3D structure; by default coloured by model confidence (blue = very high, orange = very low, typical of disordered regions).
Shieldin complex subunit 2 (SHLD2) — Shieldin complex subunit 2 — human protein (gene SHLD2, 835 amino acids, UniProt Q86V20). AlphaFold-predicted 3D structure; by default coloured by model confidence (blue = very high, orange = very low, typical of disordered regions).
ATP-dependent chromatin remodeler CHD1L (CHD1L) — ATP-dependent chromatin remodeler CHD1L — human protein (gene CHD1L, 897 amino acids, UniProt Q86WJ1). AlphaFold-predicted 3D structure; by default coloured by model confidence (blue = very high, orange = very low, typical of disordered regions).
Swi5-dependent recombination DNA repair protein 1 homolog (SFR1) — Swi5-dependent recombination DNA repair protein 1 homolog — human protein (gene SFR1, 245 amino acids, UniProt Q86XK3). AlphaFold-predicted 3D structure; by default coloured by model confidence (blue = very high, orange = very low, typical of disordered regions).
5'-3' DNA helicase ZGRF1 (ZGRF1) — 5'-3' DNA helicase ZGRF1 — human protein (gene ZGRF1, 2104 amino acids, UniProt Q86YA3). AlphaFold-predicted 3D structure; by default coloured by model confidence (blue = very high, orange = very low, typical of disordered regions).
Partner and localizer of BRCA2 (PALB2) — Partner and localizer of BRCA2 — human protein (gene PALB2, 1186 amino acids, UniProt Q86YC2). AlphaFold-predicted 3D structure; by default coloured by model confidence (blue = very high, orange = very low, typical of disordered regions).
Aprataxin and PNK-like factor (APLF) — Aprataxin and PNK-like factor — human protein (gene APLF, 511 amino acids, UniProt Q8IW19). AlphaFold-predicted 3D structure; by default coloured by model confidence (blue = very high, orange = very low, typical of disordered regions).
SMC5-SMC6 complex localization factor protein 2 (SLF2) — SMC5-SMC6 complex localization factor protein 2 — human protein (gene SLF2, 1173 amino acids, UniProt Q8IX21). AlphaFold-predicted 3D structure; by default coloured by model confidence (blue = very high, orange = very low, typical of disordered regions).
Protein mono-ADP-ribosyltransferase PARP9 (PARP9) — Protein mono-ADP-ribosyltransferase PARP9 — human protein (gene PARP9, 854 amino acids, UniProt Q8IXQ6). AlphaFold-predicted 3D structure; by default coloured by model confidence (blue = very high, orange = very low, typical of disordered regions).
Structural maintenance of chromosomes protein 5 (SMC5) — Structural maintenance of chromosomes protein 5 — human protein (gene SMC5, 1101 amino acids, UniProt Q8IY18). AlphaFold-predicted 3D structure; by default coloured by model confidence (blue = very high, orange = very low, typical of disordered regions).
Structure-specific endonuclease subunit SLX4 (SLX4) — Structure-specific endonuclease subunit SLX4 — human protein (gene SLX4, 1834 amino acids, UniProt Q8IY92). AlphaFold-predicted 3D structure; by default coloured by model confidence (blue = very high, orange = very low, typical of disordered regions).
Fanconi anemia group M protein (FANCM) — Fanconi anemia group M protein — human protein (gene FANCM, 2048 amino acids, UniProt Q8IYD8). AlphaFold-predicted 3D structure; by default coloured by model confidence (blue = very high, orange = very low, typical of disordered regions).
Shieldin complex subunit 1 (SHLD1) — Shieldin complex subunit 1 — human protein (gene SHLD1, 205 amino acids, UniProt Q8IYI0). AlphaFold-predicted 3D structure; by default coloured by model confidence (blue = very high, orange = very low, typical of disordered regions).
E3 ubiquitin-protein ligase RNF168 (RNF168) — E3 ubiquitin-protein ligase RNF168 — human protein (gene RNF168, 571 amino acids, UniProt Q8IYW5). AlphaFold-predicted 3D structure; by default coloured by model confidence (blue = very high, orange = very low, typical of disordered regions).
Tetratricopeptide repeat protein 5 (TTC5) — Tetratricopeptide repeat protein 5 — human protein (gene TTC5, 440 amino acids, UniProt Q8N0Z6). AlphaFold-predicted 3D structure; by default coloured by model confidence (blue = very high, orange = very low, typical of disordered regions).
EP300-interacting inhibitor of differentiation 3 (EID3) — EP300-interacting inhibitor of differentiation 3 — human protein (gene EID3, 333 amino acids, UniProt Q8N140). AlphaFold-predicted 3D structure; by default coloured by model confidence (blue = very high, orange = very low, typical of disordered regions).
Centromere protein S (CENPS) — Centromere protein S — human protein (gene CENPS, 138 amino acids, UniProt Q8N2Z9). AlphaFold-predicted 3D structure; by default coloured by model confidence (blue = very high, orange = very low, typical of disordered regions).
Activating signal cointegrator 1 complex subunit 3 (ASCC3) — Activating signal cointegrator 1 complex subunit 3 — human protein (gene ASCC3, 2202 amino acids, UniProt Q8N3C0). AlphaFold-predicted 3D structure; by default coloured by model confidence (blue = very high, orange = very low, typical of disordered regions).
Homologous recombination OB-fold protein (HROB) — Homologous recombination OB-fold protein — human protein (gene HROB, 647 amino acids, UniProt Q8N3J3). AlphaFold-predicted 3D structure; by default coloured by model confidence (blue = very high, orange = very low, typical of disordered regions).
NAD-dependent protein deacylase sirtuin-6 (SIRT6) — NAD-dependent protein deacylase sirtuin-6 — human protein (gene SIRT6, 355 amino acids, UniProt Q8N6T7). AlphaFold-predicted 3D structure; by default coloured by model confidence (blue = very high, orange = very low, typical of disordered regions).
Cyclic GMP-AMP synthase (CGAS) — Cyclic GMP-AMP synthase — human protein (gene CGAS, 522 amino acids, UniProt Q8N884). AlphaFold-predicted 3D structure; by default coloured by model confidence (blue = very high, orange = very low, typical of disordered regions).
Junction-mediating and -regulatory protein (JMY) — Junction-mediating and -regulatory protein — human protein (gene JMY, 988 amino acids, UniProt Q8N9B5). AlphaFold-predicted 3D structure; by default coloured by model confidence (blue = very high, orange = very low, typical of disordered regions).
Activating signal cointegrator 1 complex subunit 1 (ASCC1) — Activating signal cointegrator 1 complex subunit 1 — human protein (gene ASCC1, 400 amino acids, UniProt Q8N9N2). AlphaFold-predicted 3D structure; by default coloured by model confidence (blue = very high, orange = very low, typical of disordered regions).
Structure-specific endonuclease ANKLE1 (ANKLE1) — Structure-specific endonuclease ANKLE1 — human protein (gene ANKLE1, 615 amino acids, UniProt Q8NAG6). AlphaFold-predicted 3D structure; by default coloured by model confidence (blue = very high, orange = very low, typical of disordered regions).
Fanconi anemia group B protein (FANCB) — Fanconi anemia group B protein — human protein (gene FANCB, 859 amino acids, UniProt Q8NB91). AlphaFold-predicted 3D structure; by default coloured by model confidence (blue = very high, orange = very low, typical of disordered regions).
INO80 complex subunit E (INO80E) — INO80 complex subunit E — human protein (gene INO80E, 244 amino acids, UniProt Q8NBZ0). AlphaFold-predicted 3D structure; by default coloured by model confidence (blue = very high, orange = very low, typical of disordered regions).
E3 ubiquitin-protein ligase RNF169 (RNF169) — E3 ubiquitin-protein ligase RNF169 — human protein (gene RNF169, 708 amino acids, UniProt Q8NCN4). AlphaFold-predicted 3D structure; by default coloured by model confidence (blue = very high, orange = very low, typical of disordered regions).
F-box DNA helicase 1 (FBH1) — F-box DNA helicase 1 — human protein (gene FBH1, 1043 amino acids, UniProt Q8NFZ0). AlphaFold-predicted 3D structure; by default coloured by model confidence (blue = very high, orange = very low, typical of disordered regions).
DNA helicase B (HELB) — DNA helicase B — human protein (gene HELB, 1087 amino acids, UniProt Q8NG08). AlphaFold-predicted 3D structure; by default coloured by model confidence (blue = very high, orange = very low, typical of disordered regions).
WD repeat-containing protein 48 (WDR48) — WD repeat-containing protein 48 — human protein (gene WDR48, 677 amino acids, UniProt Q8TAF3). AlphaFold-predicted 3D structure; by default coloured by model confidence (blue = very high, orange = very low, typical of disordered regions).
Endonuclease 8-like 3 (NEIL3) — Endonuclease 8-like 3 — human protein (gene NEIL3, 605 amino acids, UniProt Q8TAT5). AlphaFold-predicted 3D structure; by default coloured by model confidence (blue = very high, orange = very low, typical of disordered regions).
E3 ubiquitin-protein ligase DTX3L (DTX3L) — E3 ubiquitin-protein ligase DTX3L — human protein (gene DTX3L, 740 amino acids, UniProt Q8TDB6). AlphaFold-predicted 3D structure; by default coloured by model confidence (blue = very high, orange = very low, typical of disordered regions).
Helicase POLQ-like (HELQ) — Helicase POLQ-like — human protein (gene HELQ, 1101 amino acids, UniProt Q8TDG4). AlphaFold-predicted 3D structure; by default coloured by model confidence (blue = very high, orange = very low, typical of disordered regions).
D-aminoacyl-tRNA deacylase 1 (DTD1) — D-aminoacyl-tRNA deacylase 1 — human protein (gene DTD1, 209 amino acids, UniProt Q8TEA8). AlphaFold-predicted 3D structure; by default coloured by model confidence (blue = very high, orange = very low, typical of disordered regions).
Non-structural maintenance of chromosomes element 1 homolog (NSMCE1) — Non-structural maintenance of chromosomes element 1 homolog — human protein (gene NSMCE1, 266 amino acids, UniProt Q8WV22). AlphaFold-predicted 3D structure; by default coloured by model confidence (blue = very high, orange = very low, typical of disordered regions).
Chromosome transmission fidelity protein 18 homolog (CHTF18) — Chromosome transmission fidelity protein 18 homolog — human protein (gene CHTF18, 975 amino acids, UniProt Q8WVB6). AlphaFold-predicted 3D structure; by default coloured by model confidence (blue = very high, orange = very low, typical of disordered regions).
E3 ubiquitin-protein ligase RNF138 (RNF138) — E3 ubiquitin-protein ligase RNF138 — human protein (gene RNF138, 245 amino acids, UniProt Q8WVD3). AlphaFold-predicted 3D structure; by default coloured by model confidence (blue = very high, orange = very low, typical of disordered regions).
ATR-interacting protein (ATRIP) — ATR-interacting protein — human protein (gene ATRIP, 791 amino acids, UniProt Q8WXE1). AlphaFold-predicted 3D structure; by default coloured by model confidence (blue = very high, orange = very low, typical of disordered regions).
DNA damage-binding protein 2 (DDB2) — DNA damage-binding protein 2 — human protein (gene DDB2, 427 amino acids, UniProt Q92466). AlphaFold-predicted 3D structure; by default coloured by model confidence (blue = very high, orange = very low, typical of disordered regions).
DNA topoisomerase 2-binding protein 1 (TOPBP1) — DNA topoisomerase 2-binding protein 1 — human protein (gene TOPBP1, 1522 amino acids, UniProt Q92547). AlphaFold-predicted 3D structure; by default coloured by model confidence (blue = very high, orange = very low, typical of disordered regions).
DNA repair and recombination protein RAD54-like (RAD54L) — DNA repair and recombination protein RAD54-like — human protein (gene RAD54L, 747 amino acids, UniProt Q92698). AlphaFold-predicted 3D structure; by default coloured by model confidence (blue = very high, orange = very low, typical of disordered regions).
General transcription factor IIH subunit 4 (GTF2H4) — General transcription factor IIH subunit 4 — human protein (gene GTF2H4, 462 amino acids, UniProt Q92759). AlphaFold-predicted 3D structure; by default coloured by model confidence (blue = very high, orange = very low, typical of disordered regions).
DNA repair protein RAD50 (RAD50) — DNA repair protein RAD50 — human protein (gene RAD50, 1312 amino acids, UniProt Q92878). AlphaFold-predicted 3D structure; by default coloured by model confidence (blue = very high, orange = very low, typical of disordered regions).
DNA repair endonuclease XPF (ERCC4) — DNA repair endonuclease XPF — human protein (gene ERCC4, 916 amino acids, UniProt Q92889). AlphaFold-predicted 3D structure; by default coloured by model confidence (blue = very high, orange = very low, typical of disordered regions).
Histone acetyltransferase KAT5 (KAT5) — Histone acetyltransferase KAT5 — human protein (gene KAT5, 513 amino acids, UniProt Q92993). AlphaFold-predicted 3D structure; by default coloured by model confidence (blue = very high, orange = very low, typical of disordered regions).