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Human proteins (AlphaFold) · Epigenetic writers, readers & erasers: 75 3D models

DNA, RNA, nucleic-acid drugs, gene editing, proteins and 300+ real PDB structures (real sizes 1–100 nm). Each one is a ready-made 3D model you can turn, recolour and place in a figure — open BioDiorama and type its name in the Library search.

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PHD finger protein 20-like protein 1 (PHF20L1) — PHD finger protein 20-like protein 1 — human protein (gene PHF20L1, 1017 amino acids, UniProt A8MW92). AlphaFold-predicted 3D structure; by default coloured by model confidence (blue = very high, orange = very low, typical of disordered regions).
AH receptor-interacting protein (AIP) — AH receptor-interacting protein — human protein (gene AIP, 330 amino acids, UniProt O00170). AlphaFold-predicted 3D structure; by default coloured by model confidence (blue = very high, orange = very low, typical of disordered regions).
Transcription initiation factor TFIID subunit 4 (TAF4) — Transcription initiation factor TFIID subunit 4 — human protein (gene TAF4, 1085 amino acids, UniProt O00268). AlphaFold-predicted 3D structure; by default coloured by model confidence (blue = very high, orange = very low, typical of disordered regions).
Transcription elongation regulator 1 (TCERG1) — Transcription elongation regulator 1 — human protein (gene TCERG1, 1098 amino acids, UniProt O14776). AlphaFold-predicted 3D structure; by default coloured by model confidence (blue = very high, orange = very low, typical of disordered regions).
Histone acetyltransferase type B catalytic subunit (HAT1) — Histone acetyltransferase type B catalytic subunit — human protein (gene HAT1, 419 amino acids, UniProt O14929). AlphaFold-predicted 3D structure; by default coloured by model confidence (blue = very high, orange = very low, typical of disordered regions).
Exportin-1 (XPO1) — Exportin-1 — human protein (gene XPO1, 1071 amino acids, UniProt O14980). AlphaFold-predicted 3D structure; by default coloured by model confidence (blue = very high, orange = very low, typical of disordered regions).
Mediator of RNA polymerase II transcription subunit 14 (MED14) — Mediator of RNA polymerase II transcription subunit 14 — human protein (gene MED14, 1454 amino acids, UniProt O60244). AlphaFold-predicted 3D structure; by default coloured by model confidence (blue = very high, orange = very low, typical of disordered regions).
Cyclin-T1 (CCNT1) — Cyclin-T1 — human protein (gene CCNT1, 726 amino acids, UniProt O60563). AlphaFold-predicted 3D structure; by default coloured by model confidence (blue = very high, orange = very low, typical of disordered regions).
Protein arginine N-methyltransferase 3 (PRMT3) — Protein arginine N-methyltransferase 3 — human protein (gene PRMT3, 531 amino acids, UniProt O60678). AlphaFold-predicted 3D structure; by default coloured by model confidence (blue = very high, orange = very low, typical of disordered regions).
Mediator of RNA polymerase II transcription subunit 24 (MED24) — Mediator of RNA polymerase II transcription subunit 24 — human protein (gene MED24, 989 amino acids, UniProt O75448). AlphaFold-predicted 3D structure; by default coloured by model confidence (blue = very high, orange = very low, typical of disordered regions).
Geminin (GMNN) — Geminin — human protein (gene GMNN, 209 amino acids, UniProt O75496). AlphaFold-predicted 3D structure; by default coloured by model confidence (blue = very high, orange = very low, typical of disordered regions).
Transcriptional adapter 3 (TADA3) — Transcriptional adapter 3 — human protein (gene TADA3, 432 amino acids, UniProt O75528). AlphaFold-predicted 3D structure; by default coloured by model confidence (blue = very high, orange = very low, typical of disordered regions).
Wolframin (WFS1) — Wolframin — human protein (gene WFS1, 890 amino acids, UniProt O76024). AlphaFold-predicted 3D structure; by default coloured by model confidence (blue = very high, orange = very low, typical of disordered regions).
Metastasis-associated protein MTA2 (MTA2) — Metastasis-associated protein MTA2 — human protein (gene MTA2, 668 amino acids, UniProt O94776). AlphaFold-predicted 3D structure; by default coloured by model confidence (blue = very high, orange = very low, typical of disordered regions).
PHD finger protein 14 (PHF14) — PHD finger protein 14 — human protein (gene PHF14, 948 amino acids, UniProt O94880). AlphaFold-predicted 3D structure; by default coloured by model confidence (blue = very high, orange = very low, typical of disordered regions).
Importin-7 (IPO7) — Importin-7 — human protein (gene IPO7, 1038 amino acids, UniProt O95373). AlphaFold-predicted 3D structure; by default coloured by model confidence (blue = very high, orange = very low, typical of disordered regions).
Prothymosin alpha (PTMA) — Prothymosin alpha — human protein (gene PTMA, 111 amino acids, UniProt P06454). AlphaFold-predicted 3D structure; by default coloured by model confidence (blue = very high, orange = very low, typical of disordered regions).
Annexin A4 (ANXA4) — Annexin A4 — human protein (gene ANXA4, 319 amino acids, UniProt P09525). AlphaFold-predicted 3D structure; by default coloured by model confidence (blue = very high, orange = very low, typical of disordered regions).
Hematopoietic lineage cell-specific protein (HCLS1) — Hematopoietic lineage cell-specific protein — human protein (gene HCLS1, 486 amino acids, UniProt P14317). AlphaFold-predicted 3D structure; by default coloured by model confidence (blue = very high, orange = very low, typical of disordered regions).
Regulator of chromosome condensation (RCC1) — Regulator of chromosome condensation — human protein (gene RCC1, 421 amino acids, UniProt P18754). AlphaFold-predicted 3D structure; by default coloured by model confidence (blue = very high, orange = very low, typical of disordered regions).
NF-kappa-B inhibitor alpha (NFKBIA) — NF-kappa-B inhibitor alpha — human protein (gene NFKBIA, 317 amino acids, UniProt P25963). AlphaFold-predicted 3D structure; by default coloured by model confidence (blue = very high, orange = very low, typical of disordered regions).
Sorcin (SRI) — Sorcin — human protein (gene SRI, 198 amino acids, UniProt P30626). AlphaFold-predicted 3D structure; by default coloured by model confidence (blue = very high, orange = very low, typical of disordered regions).
Acidic leucine-rich nuclear phosphoprotein 32 family member A (ANP32A) — Acidic leucine-rich nuclear phosphoprotein 32 family member A — human protein (gene ANP32A, 249 amino acids, UniProt P39687). AlphaFold-predicted 3D structure; by default coloured by model confidence (blue = very high, orange = very low, typical of disordered regions).
Pre-B-cell leukemia transcription factor 2 (PBX2) — Pre-B-cell leukemia transcription factor 2 — human protein (gene PBX2, 430 amino acids, UniProt P40425). AlphaFold-predicted 3D structure; by default coloured by model confidence (blue = very high, orange = very low, typical of disordered regions).
Signal transducer and activator of transcription 5A (STAT5A) — Signal transducer and activator of transcription 5A — human protein (gene STAT5A, 794 amino acids, UniProt P42229). AlphaFold-predicted 3D structure; by default coloured by model confidence (blue = very high, orange = very low, typical of disordered regions).
Condensin-2 complex subunit D3 (NCAPD3) — Condensin-2 complex subunit D3 — human protein (gene NCAPD3, 1498 amino acids, UniProt P42695). AlphaFold-predicted 3D structure; by default coloured by model confidence (blue = very high, orange = very low, typical of disordered regions).
Homeobox protein Nkx-2.1 (NKX2-1) — Homeobox protein Nkx-2.1 — human protein (gene NKX2-1, 371 amino acids, UniProt P43699). AlphaFold-predicted 3D structure; by default coloured by model confidence (blue = very high, orange = very low, typical of disordered regions).
Crk-like protein (CRKL) — Crk-like protein — human protein (gene CRKL, 303 amino acids, UniProt P46109). AlphaFold-predicted 3D structure; by default coloured by model confidence (blue = very high, orange = very low, typical of disordered regions).
DNA-binding protein inhibitor ID-4 (ID4) — DNA-binding protein inhibitor ID-4 — human protein (gene ID4, 161 amino acids, UniProt P47928). AlphaFold-predicted 3D structure; by default coloured by model confidence (blue = very high, orange = very low, typical of disordered regions).
Transcription factor SOX-9 (SOX9) — Transcription factor SOX-9 — human protein (gene SOX9, 509 amino acids, UniProt P48436). AlphaFold-predicted 3D structure; by default coloured by model confidence (blue = very high, orange = very low, typical of disordered regions).
Nuclear receptor-interacting protein 1 (NRIP1) — Nuclear receptor-interacting protein 1 — human protein (gene NRIP1, 1158 amino acids, UniProt P48552). AlphaFold-predicted 3D structure; by default coloured by model confidence (blue = very high, orange = very low, typical of disordered regions).
SWI/SNF-related matrix-associated actin-dependent regulator of chromatin subfamily A member 2 (SMARCA2) — SWI/SNF-related matrix-associated actin-dependent regulator of chromatin subfamily A member 2 — human protein (gene SMARCA2, 1590 amino acids, UniProt P51531). AlphaFold-predicted 3D structure; by default coloured by model confidence (blue = very high, orange = very low, typical of disordered regions).
Signal transducer and activator of transcription 5B (STAT5B) — Signal transducer and activator of transcription 5B — human protein (gene STAT5B, 787 amino acids, UniProt P51692). AlphaFold-predicted 3D structure; by default coloured by model confidence (blue = very high, orange = very low, typical of disordered regions).
Transcription initiation factor IIA subunit 1 (GTF2A1) — Transcription initiation factor IIA subunit 1 — human protein (gene GTF2A1, 376 amino acids, UniProt P52655). AlphaFold-predicted 3D structure; by default coloured by model confidence (blue = very high, orange = very low, typical of disordered regions).
Transcription initiation factor IIA subunit 2 (GTF2A2) — Transcription initiation factor IIA subunit 2 — human protein (gene GTF2A2, 109 amino acids, UniProt P52657). AlphaFold-predicted 3D structure; by default coloured by model confidence (blue = very high, orange = very low, typical of disordered regions).
CCAAT/enhancer-binding protein gamma (CEBPG) — CCAAT/enhancer-binding protein gamma — human protein (gene CEBPG, 150 amino acids, UniProt P53567). AlphaFold-predicted 3D structure; by default coloured by model confidence (blue = very high, orange = very low, typical of disordered regions).
Protein arginine N-methyltransferase 2 (PRMT2) — Protein arginine N-methyltransferase 2 — human protein (gene PRMT2, 433 amino acids, UniProt P55345). AlphaFold-predicted 3D structure; by default coloured by model confidence (blue = very high, orange = very low, typical of disordered regions).
Transcription factor SOX-10 (SOX10) — Transcription factor SOX-10 — human protein (gene SOX10, 466 amino acids, UniProt P56693). AlphaFold-predicted 3D structure; by default coloured by model confidence (blue = very high, orange = very low, typical of disordered regions).
Transcription factor SOX-8 (SOX8) — Transcription factor SOX-8 — human protein (gene SOX8, 446 amino acids, UniProt P57073). AlphaFold-predicted 3D structure; by default coloured by model confidence (blue = very high, orange = very low, typical of disordered regions).
Forkhead box protein L2 (FOXL2) — Forkhead box protein L2 — human protein (gene FOXL2, 376 amino acids, UniProt P58012). AlphaFold-predicted 3D structure; by default coloured by model confidence (blue = very high, orange = very low, typical of disordered regions).
Actin, cytoplasmic 1 (ACTB) — Actin, cytoplasmic 1 — human protein (gene ACTB, 375 amino acids, UniProt P60709). AlphaFold-predicted 3D structure; by default coloured by model confidence (blue = very high, orange = very low, typical of disordered regions).
Cyclin-dependent kinases regulatory subunit 1 (CKS1B) — Cyclin-dependent kinases regulatory subunit 1 — human protein (gene CKS1B, 79 amino acids, UniProt P61024). AlphaFold-predicted 3D structure; by default coloured by model confidence (blue = very high, orange = very low, typical of disordered regions).
Protein max (MAX) — Protein max — human protein (gene MAX, 160 amino acids, UniProt P61244). AlphaFold-predicted 3D structure; by default coloured by model confidence (blue = very high, orange = very low, typical of disordered regions).
LIM domain transcription factor LMO4 (LMO4) — LIM domain transcription factor LMO4 — human protein (gene LMO4, 165 amino acids, UniProt P61968). AlphaFold-predicted 3D structure; by default coloured by model confidence (blue = very high, orange = very low, typical of disordered regions).
14-3-3 protein zeta/delta (YWHAZ) — 14-3-3 protein zeta/delta — human protein (gene YWHAZ, 245 amino acids, UniProt P63104). AlphaFold-predicted 3D structure; by default coloured by model confidence (blue = very high, orange = very low, typical of disordered regions).
General transcription factor II-I (GTF2I) — General transcription factor II-I — human protein (gene GTF2I, 998 amino acids, UniProt P78347). AlphaFold-predicted 3D structure; by default coloured by model confidence (blue = very high, orange = very low, typical of disordered regions).
TATA element modulatory factor (TMF1) — TATA element modulatory factor — human protein (gene TMF1, 1093 amino acids, UniProt P82094). AlphaFold-predicted 3D structure; by default coloured by model confidence (blue = very high, orange = very low, typical of disordered regions).
SMAD family member 3 (SMAD3) — SMAD family member 3 — human protein (gene SMAD3, 425 amino acids, UniProt P84022). AlphaFold-predicted 3D structure; by default coloured by model confidence (blue = very high, orange = very low, typical of disordered regions).
Transcription initiation factor IIB (GTF2B) — Transcription initiation factor IIB — human protein (gene GTF2B, 316 amino acids, UniProt Q00403). AlphaFold-predicted 3D structure; by default coloured by model confidence (blue = very high, orange = very low, typical of disordered regions).
Transcriptional activator protein Pur-alpha (PURA) — Transcriptional activator protein Pur-alpha — human protein (gene PURA, 322 amino acids, UniProt Q00577). AlphaFold-predicted 3D structure; by default coloured by model confidence (blue = very high, orange = very low, typical of disordered regions).
Transcription factor Sp3 (SP3) — Transcription factor Sp3 — human protein (gene SP3, 781 amino acids, UniProt Q02447). AlphaFold-predicted 3D structure; by default coloured by model confidence (blue = very high, orange = very low, typical of disordered regions).
DNA-binding protein inhibitor ID-3 (ID3) — DNA-binding protein inhibitor ID-3 — human protein (gene ID3, 119 amino acids, UniProt Q02535). AlphaFold-predicted 3D structure; by default coloured by model confidence (blue = very high, orange = very low, typical of disordered regions).
14-3-3 protein eta (YWHAH) — 14-3-3 protein eta — human protein (gene YWHAH, 246 amino acids, UniProt Q04917). AlphaFold-predicted 3D structure; by default coloured by model confidence (blue = very high, orange = very low, typical of disordered regions).
Sex-determining region Y protein (SRY) — Sex-determining region Y protein — human protein (gene SRY, 204 amino acids, UniProt Q05066). AlphaFold-predicted 3D structure; by default coloured by model confidence (blue = very high, orange = very low, typical of disordered regions).
Histone acetyltransferase p300 (EP300) — Histone acetyltransferase p300 — human protein (gene EP300, 2414 amino acids, UniProt Q09472). AlphaFold-predicted 3D structure; by default coloured by model confidence (blue = very high, orange = very low, typical of disordered regions).
Transcription initiation factor TFIID subunit 10 (TAF10) — Transcription initiation factor TFIID subunit 10 — human protein (gene TAF10, 218 amino acids, UniProt Q12962). AlphaFold-predicted 3D structure; by default coloured by model confidence (blue = very high, orange = very low, typical of disordered regions).
PR domain zinc finger protein 2 (PRDM2) — PR domain zinc finger protein 2 — human protein (gene PRDM2, 1718 amino acids, UniProt Q13029). AlphaFold-predicted 3D structure; by default coloured by model confidence (blue = very high, orange = very low, typical of disordered regions).
RE1-silencing transcription factor (REST) — RE1-silencing transcription factor — human protein (gene REST, 1097 amino acids, UniProt Q13127). AlphaFold-predicted 3D structure; by default coloured by model confidence (blue = very high, orange = very low, typical of disordered regions).
Metastasis-associated protein MTA1 (MTA1) — Metastasis-associated protein MTA1 — human protein (gene MTA1, 715 amino acids, UniProt Q13330). AlphaFold-predicted 3D structure; by default coloured by model confidence (blue = very high, orange = very low, typical of disordered regions).
C-terminal-binding protein 1 (CTBP1) — C-terminal-binding protein 1 — human protein (gene CTBP1, 440 amino acids, UniProt Q13363). AlphaFold-predicted 3D structure; by default coloured by model confidence (blue = very high, orange = very low, typical of disordered regions).
SMAD family member 4 (SMAD4) — SMAD family member 4 — human protein (gene SMAD4, 552 amino acids, UniProt Q13485). AlphaFold-predicted 3D structure; by default coloured by model confidence (blue = very high, orange = very low, typical of disordered regions).
Acid ceramidase (ASAH1) — Acid ceramidase — human protein (gene ASAH1, 395 amino acids, UniProt Q13510). AlphaFold-predicted 3D structure; by default coloured by model confidence (blue = very high, orange = very low, typical of disordered regions).
Krueppel-like factor 5 (KLF5) — Krueppel-like factor 5 — human protein (gene KLF5, 457 amino acids, UniProt Q13887). AlphaFold-predicted 3D structure; by default coloured by model confidence (blue = very high, orange = very low, typical of disordered regions).
Protein Tob2 (TOB2) — Protein Tob2 — human protein (gene TOB2, 344 amino acids, UniProt Q14106). AlphaFold-predicted 3D structure; by default coloured by model confidence (blue = very high, orange = very low, typical of disordered regions).
Transcription factor Dp-1 (TFDP1) — Transcription factor Dp-1 — human protein (gene TFDP1, 410 amino acids, UniProt Q14186). AlphaFold-predicted 3D structure; by default coloured by model confidence (blue = very high, orange = very low, typical of disordered regions).
Four and a half LIM domains protein 2 (FHL2) — Four and a half LIM domains protein 2 — human protein (gene FHL2, 279 amino acids, UniProt Q14192). AlphaFold-predicted 3D structure; by default coloured by model confidence (blue = very high, orange = very low, typical of disordered regions).
Nuclear receptor coactivator 6 (NCOA6) — Nuclear receptor coactivator 6 — human protein (gene NCOA6, 2063 amino acids, UniProt Q14686). AlphaFold-predicted 3D structure; by default coloured by model confidence (blue = very high, orange = very low, typical of disordered regions).
Condensin complex subunit 1 (NCAPD2) — Condensin complex subunit 1 — human protein (gene NCAPD2, 1401 amino acids, UniProt Q15021). AlphaFold-predicted 3D structure; by default coloured by model confidence (blue = very high, orange = very low, typical of disordered regions).
DAZ-associated protein 2 (DAZAP2) — DAZ-associated protein 2 — human protein (gene DAZAP2, 168 amino acids, UniProt Q15038). AlphaFold-predicted 3D structure; by default coloured by model confidence (blue = very high, orange = very low, typical of disordered regions).
Ankyrin repeat domain-containing protein 1 (ANKRD1) — Ankyrin repeat domain-containing protein 1 — human protein (gene ANKRD1, 319 amino acids, UniProt Q15327). AlphaFold-predicted 3D structure; by default coloured by model confidence (blue = very high, orange = very low, typical of disordered regions).
Transcription initiation factor TFIID subunit 11 (TAF11) — Transcription initiation factor TFIID subunit 11 — human protein (gene TAF11, 211 amino acids, UniProt Q15544). AlphaFold-predicted 3D structure; by default coloured by model confidence (blue = very high, orange = very low, typical of disordered regions).
Transcription initiation factor TFIID subunit 7 (TAF7) — Transcription initiation factor TFIID subunit 7 — human protein (gene TAF7, 349 amino acids, UniProt Q15545). AlphaFold-predicted 3D structure; by default coloured by model confidence (blue = very high, orange = very low, typical of disordered regions).
Mediator of RNA polymerase II transcription subunit 1 (MED1) — Mediator of RNA polymerase II transcription subunit 1 — human protein (gene MED1, 1581 amino acids, UniProt Q15648). AlphaFold-predicted 3D structure; by default coloured by model confidence (blue = very high, orange = very low, typical of disordered regions).
Zinc finger HIT domain-containing protein 3 (ZNHIT3) — Zinc finger HIT domain-containing protein 3 — human protein (gene ZNHIT3, 155 amino acids, UniProt Q15649). AlphaFold-predicted 3D structure; by default coloured by model confidence (blue = very high, orange = very low, typical of disordered regions).
Activating signal cointegrator 1 (TRIP4) — Activating signal cointegrator 1 — human protein (gene TRIP4, 581 amino acids, UniProt Q15650). AlphaFold-predicted 3D structure; by default coloured by model confidence (blue = very high, orange = very low, typical of disordered regions).