Library › DNA & Proteins › Human proteins (AlphaFold) · Ferroptosis

Human proteins (AlphaFold) · Ferroptosis: 75 3D models

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Ferritin light chain (FTL) — Ferritin light chain — human protein (gene FTL, 175 amino acids, UniProt P02792). AlphaFold-predicted 3D structure; by default coloured by model confidence (blue = very high, orange = very low, typical of disordered regions).
Ferritin heavy chain (FTH1) — Ferritin heavy chain — human protein (gene FTH1, 183 amino acids, UniProt P02794). AlphaFold-predicted 3D structure; by default coloured by model confidence (blue = very high, orange = very low, typical of disordered regions).
CDGSH iron-sulfur domain-containing protein 3, mitochondrial (CISD3) — CDGSH iron-sulfur domain-containing protein 3, mitochondrial — human protein (gene CISD3, 127 amino acids, UniProt P0C7P0). AlphaFold-predicted 3D structure; by default coloured by model confidence (blue = very high, orange = very low, typical of disordered regions).
Phosphatidylethanolamine-binding protein 1 (PEBP1) — Phosphatidylethanolamine-binding protein 1 — human protein (gene PEBP1, 187 amino acids, UniProt P30086). AlphaFold-predicted 3D structure; by default coloured by model confidence (blue = very high, orange = very low, typical of disordered regions).
Heme oxygenase 2 (HMOX2) — Heme oxygenase 2 — human protein (gene HMOX2, 316 amino acids, UniProt P30519). AlphaFold-predicted 3D structure; by default coloured by model confidence (blue = very high, orange = very low, typical of disordered regions).
GTP cyclohydrolase 1 (GCH1) — GTP cyclohydrolase 1 — human protein (gene GCH1, 250 amino acids, UniProt P30793). AlphaFold-predicted 3D structure; by default coloured by model confidence (blue = very high, orange = very low, typical of disordered regions).
Dihydroorotate dehydrogenase (DHODH) — Dihydroorotate dehydrogenase — human protein (gene DHODH, 395 amino acids, UniProt Q02127). AlphaFold-predicted 3D structure; by default coloured by model confidence (blue = very high, orange = very low, typical of disordered regions).
Squalene monooxygenase (SQLE) — Squalene monooxygenase — human protein (gene SQLE, 574 amino acids, UniProt Q14534). AlphaFold-predicted 3D structure; by default coloured by model confidence (blue = very high, orange = very low, typical of disordered regions).
Nuclear factor erythroid 2-related factor 2 (NFE2L2) — Nuclear factor erythroid 2-related factor 2 — human protein (gene NFE2L2, 605 amino acids, UniProt Q16236). AlphaFold-predicted 3D structure; by default coloured by model confidence (blue = very high, orange = very low, typical of disordered regions).
Lysophospholipid acyltransferase 5 (LPCAT3) — Lysophospholipid acyltransferase 5 — human protein (gene LPCAT3, 487 amino acids, UniProt Q6P1A2). AlphaFold-predicted 3D structure; by default coloured by model confidence (blue = very high, orange = very low, typical of disordered regions).
CDGSH iron-sulfur domain-containing protein 2 (CISD2) — CDGSH iron-sulfur domain-containing protein 2 — human protein (gene CISD2, 135 amino acids, UniProt Q8N5K1). AlphaFold-predicted 3D structure; by default coloured by model confidence (blue = very high, orange = very low, typical of disordered regions).
Ferroptosis suppressor protein 1 (AIFM2) — Ferroptosis suppressor protein 1 — human protein (gene AIFM2, 373 amino acids, UniProt Q9BRQ8). AlphaFold-predicted 3D structure; by default coloured by model confidence (blue = very high, orange = very low, typical of disordered regions).
Hydroperoxide isomerase ALOXE3 (ALOXE3) — Hydroperoxide isomerase ALOXE3 — human protein (gene ALOXE3, 711 amino acids, UniProt Q9BYJ1). AlphaFold-predicted 3D structure; by default coloured by model confidence (blue = very high, orange = very low, typical of disordered regions).
Autophagy protein 5 (ATG5) — Autophagy protein 5 — human protein (gene ATG5, 275 amino acids, UniProt Q9H1Y0). AlphaFold-predicted 3D structure; by default coloured by model confidence (blue = very high, orange = very low, typical of disordered regions).
CDGSH iron-sulfur domain-containing protein 1 (CISD1) — CDGSH iron-sulfur domain-containing protein 1 — human protein (gene CISD1, 108 amino acids, UniProt Q9NZ45). AlphaFold-predicted 3D structure; by default coloured by model confidence (blue = very high, orange = very low, typical of disordered regions).
Cystine/glutamate transporter (SLC7A11) — Cystine/glutamate transporter — human protein (gene SLC7A11, 501 amino acids, UniProt Q9UPY5). AlphaFold-predicted 3D structure; by default coloured by model confidence (blue = very high, orange = very low, typical of disordered regions).
NADPH oxidase 1 (NOX1) — NADPH oxidase 1 — human protein (gene NOX1, 564 amino acids, UniProt Q9Y5S8). AlphaFold-predicted 3D structure; by default coloured by model confidence (blue = very high, orange = very low, typical of disordered regions).
Diamine acetyltransferase 1 (SAT1) — Diamine acetyltransferase 1 — human protein (gene SAT1, 171 amino acids, UniProt P21673). AlphaFold-predicted 3D structure; by default coloured by model confidence (blue = very high, orange = very low, typical of disordered regions).
Iron-responsive element-binding protein 2 (IREB2) — Iron-responsive element-binding protein 2 — human protein (gene IREB2, 963 amino acids, UniProt P48200). AlphaFold-predicted 3D structure; by default coloured by model confidence (blue = very high, orange = very low, typical of disordered regions).
Glutamate--cysteine ligase catalytic subunit (GCLC) — Glutamate--cysteine ligase catalytic subunit — human protein (gene GCLC, 637 amino acids, UniProt P48506). AlphaFold-predicted 3D structure; by default coloured by model confidence (blue = very high, orange = very low, typical of disordered regions).
Glutamate--cysteine ligase regulatory subunit (GCLM) — Glutamate--cysteine ligase regulatory subunit — human protein (gene GCLM, 274 amino acids, UniProt P48507). AlphaFold-predicted 3D structure; by default coloured by model confidence (blue = very high, orange = very low, typical of disordered regions).
Glutathione synthetase (GSS) — Glutathione synthetase — human protein (gene GSS, 474 amino acids, UniProt P48637). AlphaFold-predicted 3D structure; by default coloured by model confidence (blue = very high, orange = very low, typical of disordered regions).
Selenocysteine-specific elongation factor (EEFSEC) — Selenocysteine-specific elongation factor — human protein (gene EEFSEC, 596 amino acids, UniProt P57772). AlphaFold-predicted 3D structure; by default coloured by model confidence (blue = very high, orange = very low, typical of disordered regions).
Aldo-keto reductase family 1 member C1 (AKR1C1) — Aldo-keto reductase family 1 member C1 — human protein (gene AKR1C1, 323 amino acids, UniProt Q04828). AlphaFold-predicted 3D structure; by default coloured by model confidence (blue = very high, orange = very low, typical of disordered regions).
Frataxin, mitochondrial (FXN) — Frataxin, mitochondrial — human protein (gene FXN, 210 amino acids, UniProt Q16595). AlphaFold-predicted 3D structure; by default coloured by model confidence (blue = very high, orange = very low, typical of disordered regions).
Ferredoxin-2, mitochondrial (FDX2) — Ferredoxin-2, mitochondrial — human protein (gene FDX2, 183 amino acids, UniProt Q6P4F2). AlphaFold-predicted 3D structure; by default coloured by model confidence (blue = very high, orange = very low, typical of disordered regions).
Membrane-bound glycerophospholipid O-acyltransferase 1 (MBOAT1) — Membrane-bound glycerophospholipid O-acyltransferase 1 — human protein (gene MBOAT1, 495 amino acids, UniProt Q6ZNC8). AlphaFold-predicted 3D structure; by default coloured by model confidence (blue = very high, orange = very low, typical of disordered regions).
Membrane-bound glycerophospholipid O-acyltransferase 2 (MBOAT2) — Membrane-bound glycerophospholipid O-acyltransferase 2 — human protein (gene MBOAT2, 520 amino acids, UniProt Q6ZWT7). AlphaFold-predicted 3D structure; by default coloured by model confidence (blue = very high, orange = very low, typical of disordered regions).
Selenocysteine insertion sequence-binding protein 2 (SECISBP2) — Selenocysteine insertion sequence-binding protein 2 — human protein (gene SECISBP2, 854 amino acids, UniProt Q96T21). AlphaFold-predicted 3D structure; by default coloured by model confidence (blue = very high, orange = very low, typical of disordered regions).
Glutathione-specific gamma-glutamylcyclotransferase 1 (CHAC1) — Glutathione-specific gamma-glutamylcyclotransferase 1 — human protein (gene CHAC1, 222 amino acids, UniProt Q9BUX1). AlphaFold-predicted 3D structure; by default coloured by model confidence (blue = very high, orange = very low, typical of disordered regions).
Iron-sulfur cluster assembly enzyme ISCU (ISCU) — Iron-sulfur cluster assembly enzyme ISCU — human protein (gene ISCU, 167 amino acids, UniProt Q9H1K1). AlphaFold-predicted 3D structure; by default coloured by model confidence (blue = very high, orange = very low, typical of disordered regions).
Sodium-coupled neutral amino acid symporter 1 (SLC38A1) — Sodium-coupled neutral amino acid symporter 1 — human protein (gene SLC38A1, 487 amino acids, UniProt Q9H2H9). AlphaFold-predicted 3D structure; by default coloured by model confidence (blue = very high, orange = very low, typical of disordered regions).
tRNA dimethylallyltransferase (TRIT1) — tRNA dimethylallyltransferase — human protein (gene TRIT1, 467 amino acids, UniProt Q9H3H1). AlphaFold-predicted 3D structure; by default coloured by model confidence (blue = very high, orange = very low, typical of disordered regions).
O-phosphoseryl-tRNA(Sec) selenium transferase (SEPSECS) — O-phosphoseryl-tRNA(Sec) selenium transferase — human protein (gene SEPSECS, 501 amino acids, UniProt Q9HD40). AlphaFold-predicted 3D structure; by default coloured by model confidence (blue = very high, orange = very low, typical of disordered regions).
Ferroportin (SLC40A1) — Ferroportin — human protein (gene SLC40A1, 571 amino acids, UniProt Q9NP59). AlphaFold-predicted 3D structure; by default coloured by model confidence (blue = very high, orange = very low, typical of disordered regions).
NADPH oxidase 4 (NOX4) — NADPH oxidase 4 — human protein (gene NOX4, 578 amino acids, UniProt Q9NPH5). AlphaFold-predicted 3D structure; by default coloured by model confidence (blue = very high, orange = very low, typical of disordered regions).
Very long chain fatty acid elongase 5 (ELOVL5) — Very long chain fatty acid elongase 5 — human protein (gene ELOVL5, 299 amino acids, UniProt Q9NYP7). AlphaFold-predicted 3D structure; by default coloured by model confidence (blue = very high, orange = very low, typical of disordered regions).
Transferrin receptor protein 2 (TFR2) — Transferrin receptor protein 2 — human protein (gene TFR2, 801 amino acids, UniProt Q9UP52). AlphaFold-predicted 3D structure; by default coloured by model confidence (blue = very high, orange = very low, typical of disordered regions).
Cysteine desulfurase (NFS1) — Cysteine desulfurase — human protein (gene NFS1, 457 amino acids, UniProt Q9Y697). AlphaFold-predicted 3D structure; by default coloured by model confidence (blue = very high, orange = very low, typical of disordered regions).
NAD(P)H dehydrogenase [quinone] 1 (NQO1) — NAD(P)H dehydrogenase [quinone] 1 — human protein (gene NQO1, 274 amino acids, UniProt P15559). AlphaFold-predicted 3D structure; by default coloured by model confidence (blue = very high, orange = very low, typical of disordered regions).
Zinc finger E-box-binding homeobox 1 (ZEB1) — Zinc finger E-box-binding homeobox 1 — human protein (gene ZEB1, 1124 amino acids, UniProt P37275). AlphaFold-predicted 3D structure; by default coloured by model confidence (blue = very high, orange = very low, typical of disordered regions).
Cyclin-dependent kinase inhibitor 1 (CDKN1A) — Cyclin-dependent kinase inhibitor 1 — human protein (gene CDKN1A, 164 amino acids, UniProt P38936). AlphaFold-predicted 3D structure; by default coloured by model confidence (blue = very high, orange = very low, typical of disordered regions).
Caveolin-1 (CAV1) — Caveolin-1 — human protein (gene CAV1, 178 amino acids, UniProt Q03135). AlphaFold-predicted 3D structure; by default coloured by model confidence (blue = very high, orange = very low, typical of disordered regions).
Tafazzin (TAFAZZIN) — Tafazzin — human protein (gene TAFAZZIN, 262 amino acids, UniProt Q16635). AlphaFold-predicted 3D structure; by default coloured by model confidence (blue = very high, orange = very low, typical of disordered regions).
Hypoxia-inducible factor 1-alpha (HIF1A) — Hypoxia-inducible factor 1-alpha — human protein (gene HIF1A, 826 amino acids, UniProt Q16665). AlphaFold-predicted 3D structure; by default coloured by model confidence (blue = very high, orange = very low, typical of disordered regions).
Carbonic anhydrase 9 (CA9) — Carbonic anhydrase 9 — human protein (gene CA9, 459 amino acids, UniProt Q16790). AlphaFold-predicted 3D structure; by default coloured by model confidence (blue = very high, orange = very low, typical of disordered regions).
Prominin-2 (PROM2) — Prominin-2 — human protein (gene PROM2, 834 amino acids, UniProt Q8N271). AlphaFold-predicted 3D structure; by default coloured by model confidence (blue = very high, orange = very low, typical of disordered regions).
Ferritin, mitochondrial (FTMT) — Ferritin, mitochondrial — human protein (gene FTMT, 242 amino acids, UniProt Q8N4E7). AlphaFold-predicted 3D structure; by default coloured by model confidence (blue = very high, orange = very low, typical of disordered regions).
Lysophosphatidylcholine acyltransferase 1 (LPCAT1) — Lysophosphatidylcholine acyltransferase 1 — human protein (gene LPCAT1, 534 amino acids, UniProt Q8NF37). AlphaFold-predicted 3D structure; by default coloured by model confidence (blue = very high, orange = very low, typical of disordered regions).
Transcription factor AP-2 gamma (TFAP2C) — Transcription factor AP-2 gamma — human protein (gene TFAP2C, 450 amino acids, UniProt Q92754). AlphaFold-predicted 3D structure; by default coloured by model confidence (blue = very high, orange = very low, typical of disordered regions).
Fanconi anemia group D2 protein (FANCD2) — Fanconi anemia group D2 protein — human protein (gene FANCD2, 1451 amino acids, UniProt Q9BXW9). AlphaFold-predicted 3D structure; by default coloured by model confidence (blue = very high, orange = very low, typical of disordered regions).
NAD-dependent protein deacetylase sirtuin-3, mitochondrial (SIRT3) — NAD-dependent protein deacetylase sirtuin-3, mitochondrial — human protein (gene SIRT3, 399 amino acids, UniProt Q9NTG7). AlphaFold-predicted 3D structure; by default coloured by model confidence (blue = very high, orange = very low, typical of disordered regions).
Glutaminase liver isoform, mitochondrial (GLS2) — Glutaminase liver isoform, mitochondrial — human protein (gene GLS2, 602 amino acids, UniProt Q9UI32). AlphaFold-predicted 3D structure; by default coloured by model confidence (blue = very high, orange = very low, typical of disordered regions).
Non-selective voltage-gated ion channel VDAC3 (VDAC3) — Non-selective voltage-gated ion channel VDAC3 — human protein (gene VDAC3, 283 amino acids, UniProt Q9Y277). AlphaFold-predicted 3D structure; by default coloured by model confidence (blue = very high, orange = very low, typical of disordered regions).
Glucose-6-phosphate 1-dehydrogenase (G6PD) — Glucose-6-phosphate 1-dehydrogenase — human protein (gene G6PD, 515 amino acids, UniProt P11413). AlphaFold-predicted 3D structure; by default coloured by model confidence (blue = very high, orange = very low, typical of disordered regions).
Lysosome-associated membrane glycoprotein 2 (LAMP2) — Lysosome-associated membrane glycoprotein 2 — human protein (gene LAMP2, 410 amino acids, UniProt P13473). AlphaFold-predicted 3D structure; by default coloured by model confidence (blue = very high, orange = very low, typical of disordered regions).
NADPH--cytochrome P450 reductase (POR) — NADPH--cytochrome P450 reductase — human protein (gene POR, 677 amino acids, UniProt P16435). AlphaFold-predicted 3D structure; by default coloured by model confidence (blue = very high, orange = very low, typical of disordered regions).
Alpha-aminoadipic semialdehyde dehydrogenase (ALDH7A1) — Alpha-aminoadipic semialdehyde dehydrogenase — human protein (gene ALDH7A1, 539 amino acids, UniProt P49419). AlphaFold-predicted 3D structure; by default coloured by model confidence (blue = very high, orange = very low, typical of disordered regions).
6-phosphogluconate dehydrogenase, decarboxylating (PGD) — 6-phosphogluconate dehydrogenase, decarboxylating — human protein (gene PGD, 483 amino acids, UniProt P52209). AlphaFold-predicted 3D structure; by default coloured by model confidence (blue = very high, orange = very low, typical of disordered regions).
Phosphoenolpyruvate carboxykinase [GTP], mitochondrial (PCK2) — Phosphoenolpyruvate carboxykinase [GTP], mitochondrial — human protein (gene PCK2, 640 amino acids, UniProt Q16822). AlphaFold-predicted 3D structure; by default coloured by model confidence (blue = very high, orange = very low, typical of disordered regions).
NADH-cytochrome b5 reductase 2 (CYB5R2) — NADH-cytochrome b5 reductase 2 — human protein (gene CYB5R2, 276 amino acids, UniProt Q6BCY4). AlphaFold-predicted 3D structure; by default coloured by model confidence (blue = very high, orange = very low, typical of disordered regions).
Zinc transporter SLC39A7 (SLC39A7) — Zinc transporter SLC39A7 — human protein (gene SLC39A7, 469 amino acids, UniProt Q92504). AlphaFold-predicted 3D structure; by default coloured by model confidence (blue = very high, orange = very low, typical of disordered regions).
Histone acetyltransferase KAT2B (KAT2B) — Histone acetyltransferase KAT2B — human protein (gene KAT2B, 832 amino acids, UniProt Q92831). AlphaFold-predicted 3D structure; by default coloured by model confidence (blue = very high, orange = very low, typical of disordered regions).
F-box/WD repeat-containing protein 7 (FBXW7) — F-box/WD repeat-containing protein 7 — human protein (gene FBXW7, 707 amino acids, UniProt Q969H0). AlphaFold-predicted 3D structure; by default coloured by model confidence (blue = very high, orange = very low, typical of disordered regions).
Prolyl hydroxylase EGLN3 (EGLN3) — Prolyl hydroxylase EGLN3 — human protein (gene EGLN3, 239 amino acids, UniProt Q9H6Z9). AlphaFold-predicted 3D structure; by default coloured by model confidence (blue = very high, orange = very low, typical of disordered regions).
E3 ubiquitin-protein ligase SMURF2 (SMURF2) — E3 ubiquitin-protein ligase SMURF2 — human protein (gene SMURF2, 748 amino acids, UniProt Q9HAU4). AlphaFold-predicted 3D structure; by default coloured by model confidence (blue = very high, orange = very low, typical of disordered regions).
Cytochrome P450 4F11 (CYP4F11) — Cytochrome P450 4F11 — human protein (gene CYP4F11, 524 amino acids, UniProt Q9HBI6). AlphaFold-predicted 3D structure; by default coloured by model confidence (blue = very high, orange = very low, typical of disordered regions).
Dual oxidase 2 (DUOX2) — Dual oxidase 2 — human protein (gene DUOX2, 1548 amino acids, UniProt Q9NRD8). AlphaFold-predicted 3D structure; by default coloured by model confidence (blue = very high, orange = very low, typical of disordered regions).
Dual oxidase 1 (DUOX1) — Dual oxidase 1 — human protein (gene DUOX1, 1551 amino acids, UniProt Q9NRD9). AlphaFold-predicted 3D structure; by default coloured by model confidence (blue = very high, orange = very low, typical of disordered regions).
Mitochondrial potassium channel ATP-binding subunit (ABCB8) — Mitochondrial potassium channel ATP-binding subunit — human protein (gene ABCB8, 735 amino acids, UniProt Q9NUT2). AlphaFold-predicted 3D structure; by default coloured by model confidence (blue = very high, orange = very low, typical of disordered regions).
7-dehydrocholesterol reductase (DHCR7) — 7-dehydrocholesterol reductase — human protein (gene DHCR7, 475 amino acids, UniProt Q9UBM7). AlphaFold-predicted 3D structure; by default coloured by model confidence (blue = very high, orange = very low, typical of disordered regions).
NADH-cytochrome b5 reductase 1 (CYB5R1) — NADH-cytochrome b5 reductase 1 — human protein (gene CYB5R1, 305 amino acids, UniProt Q9UHQ9). AlphaFold-predicted 3D structure; by default coloured by model confidence (blue = very high, orange = very low, typical of disordered regions).
Phosphoserine aminotransferase (PSAT1) — Phosphoserine aminotransferase — human protein (gene PSAT1, 370 amino acids, UniProt Q9Y617). AlphaFold-predicted 3D structure; by default coloured by model confidence (blue = very high, orange = very low, typical of disordered regions).
Transmembrane protein 164 (TMEM164) — Transmembrane protein 164 — human protein (gene TMEM164, 297 amino acids, UniProt Q5U3C3). AlphaFold-predicted 3D structure; by default coloured by model confidence (blue = very high, orange = very low, typical of disordered regions).
L-seryl-tRNA(Sec) kinase (PSTK) — L-seryl-tRNA(Sec) kinase — human protein (gene PSTK, 348 amino acids, UniProt Q8IV42). AlphaFold-predicted 3D structure; by default coloured by model confidence (blue = very high, orange = very low, typical of disordered regions).