Library › DNA & Proteins › Human proteins (AlphaFold) · GLP-1 & incretin signalling

Human proteins (AlphaFold) · GLP-1 & incretin signalling: 57 3D models

DNA, RNA, nucleic-acid drugs, gene editing, proteins and 300+ real PDB structures (real sizes 1–100 nm). Each one is a ready-made 3D model you can turn, recolour and place in a figure — open BioDiorama and type its name in the Library search.

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Agouti-related protein (AGRP) — Agouti-related protein — human protein (gene AGRP, 132 amino acids, UniProt O00253). AlphaFold-predicted 3D structure; by default coloured by model confidence (blue = very high, orange = very low, typical of disordered regions).
Leptin receptor gene-related protein (LEPROT) — Leptin receptor gene-related protein — human protein (gene LEPROT, 131 amino acids, UniProt O15243). AlphaFold-predicted 3D structure; by default coloured by model confidence (blue = very high, orange = very low, typical of disordered regions).
Pro-neuropeptide Y (NPY) — Pro-neuropeptide Y — human protein (gene NPY, 97 amino acids, UniProt P01303). AlphaFold-predicted 3D structure; by default coloured by model confidence (blue = very high, orange = very low, typical of disordered regions).
Leptin (LEP) — Leptin — human protein (gene LEP, 167 amino acids, UniProt P41159). AlphaFold-predicted 3D structure; by default coloured by model confidence (blue = very high, orange = very low, typical of disordered regions).
ProSAAS (PCSK1N) — ProSAAS — human protein (gene PCSK1N, 260 amino acids, UniProt Q9UHG2). AlphaFold-predicted 3D structure; by default coloured by model confidence (blue = very high, orange = very low, typical of disordered regions).
Fructose-1,6-bisphosphatase 1 (FBP1) — Fructose-1,6-bisphosphatase 1 — human protein (gene FBP1, 338 amino acids, UniProt P09467). AlphaFold-predicted 3D structure; by default coloured by model confidence (blue = very high, orange = very low, typical of disordered regions).
Glucose-6-phosphatase catalytic subunit 1 (G6PC1) — Glucose-6-phosphatase catalytic subunit 1 — human protein (gene G6PC1, 357 amino acids, UniProt P35575). AlphaFold-predicted 3D structure; by default coloured by model confidence (blue = very high, orange = very low, typical of disordered regions).
Hepatocyte nuclear factor 1-beta (HNF1B) — Hepatocyte nuclear factor 1-beta — human protein (gene HNF1B, 557 amino acids, UniProt P35680). AlphaFold-predicted 3D structure; by default coloured by model confidence (blue = very high, orange = very low, typical of disordered regions).
ATP-binding cassette sub-family C member 8 (ABCC8) — ATP-binding cassette sub-family C member 8 — human protein (gene ABCC8, 1581 amino acids, UniProt Q09428). AlphaFold-predicted 3D structure; by default coloured by model confidence (blue = very high, orange = very low, typical of disordered regions).
Glucokinase regulatory protein (GCKR) — Glucokinase regulatory protein — human protein (gene GCKR, 625 amino acids, UniProt Q14397). AlphaFold-predicted 3D structure; by default coloured by model confidence (blue = very high, orange = very low, typical of disordered regions).
Transcription factor MafA (MAFA) — Transcription factor MafA — human protein (gene MAFA, 353 amino acids, UniProt Q8NHW3). AlphaFold-predicted 3D structure; by default coloured by model confidence (blue = very high, orange = very low, typical of disordered regions).
Killer cell lectin-like receptor subfamily G member 1 (KLRG1) — Killer cell lectin-like receptor subfamily G member 1 — human protein (gene KLRG1, 195 amino acids, UniProt Q96E93). AlphaFold-predicted 3D structure; by default coloured by model confidence (blue = very high, orange = very low, typical of disordered regions).
Glucose-6-phosphatase 2 (G6PC2) — Glucose-6-phosphatase 2 — human protein (gene G6PC2, 355 amino acids, UniProt Q9NQR9). AlphaFold-predicted 3D structure; by default coloured by model confidence (blue = very high, orange = very low, typical of disordered regions).
Neuroendocrine secretory protein 55 (GNAS) — Neuroendocrine secretory protein 55 — human protein (gene GNAS, 245 amino acids, UniProt O95467). AlphaFold-predicted 3D structure; by default coloured by model confidence (blue = very high, orange = very low, typical of disordered regions).
Somatoliberin (GHRH) — Somatoliberin — human protein (gene GHRH, 108 amino acids, UniProt P01286). AlphaFold-predicted 3D structure; by default coloured by model confidence (blue = very high, orange = very low, typical of disordered regions).
Guanine nucleotide-binding protein subunit alpha-11 (GNA11) — Guanine nucleotide-binding protein subunit alpha-11 — human protein (gene GNA11, 359 amino acids, UniProt P29992). AlphaFold-predicted 3D structure; by default coloured by model confidence (blue = very high, orange = very low, typical of disordered regions).
Beta-arrestin-2 (ARRB2) — Beta-arrestin-2 — human protein (gene ARRB2, 409 amino acids, UniProt P32121). AlphaFold-predicted 3D structure; by default coloured by model confidence (blue = very high, orange = very low, typical of disordered regions).
Guanine nucleotide-binding protein G(olf) subunit alpha (GNAL) — Guanine nucleotide-binding protein G(olf) subunit alpha — human protein (gene GNAL, 381 amino acids, UniProt P38405). AlphaFold-predicted 3D structure; by default coloured by model confidence (blue = very high, orange = very low, typical of disordered regions).
Beta-arrestin-1 (ARRB1) — Beta-arrestin-1 — human protein (gene ARRB1, 418 amino acids, UniProt P49407). AlphaFold-predicted 3D structure; by default coloured by model confidence (blue = very high, orange = very low, typical of disordered regions).
Guanine nucleotide-binding protein G(q) subunit alpha (GNAQ) — Guanine nucleotide-binding protein G(q) subunit alpha — human protein (gene GNAQ, 359 amino acids, UniProt P50148). AlphaFold-predicted 3D structure; by default coloured by model confidence (blue = very high, orange = very low, typical of disordered regions).
Guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-2 (GNG2) — Guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-2 — human protein (gene GNG2, 71 amino acids, UniProt P59768). AlphaFold-predicted 3D structure; by default coloured by model confidence (blue = very high, orange = very low, typical of disordered regions).
Ras-related protein Rap-1b (RAP1B) — Ras-related protein Rap-1b — human protein (gene RAP1B, 184 amino acids, UniProt P61224). AlphaFold-predicted 3D structure; by default coloured by model confidence (blue = very high, orange = very low, typical of disordered regions).
Guanine nucleotide-binding protein G(I)/G(S)/G(T) subunit beta-1 (GNB1) — Guanine nucleotide-binding protein G(I)/G(S)/G(T) subunit beta-1 — human protein (gene GNB1, 340 amino acids, UniProt P62873). AlphaFold-predicted 3D structure; by default coloured by model confidence (blue = very high, orange = very low, typical of disordered regions).
Guanine nucleotide-binding protein G(i) subunit alpha-1 (GNAI1) — Guanine nucleotide-binding protein G(i) subunit alpha-1 — human protein (gene GNAI1, 354 amino acids, UniProt P63096). AlphaFold-predicted 3D structure; by default coloured by model confidence (blue = very high, orange = very low, typical of disordered regions).
Protein ALEX (GNAS) — Protein ALEX — human protein (gene GNAS, 626 amino acids, UniProt P84996). AlphaFold-predicted 3D structure; by default coloured by model confidence (blue = very high, orange = very low, typical of disordered regions).
Guanine nucleotide-binding protein G(s) subunit alpha isoforms XLas (GNAS) — Guanine nucleotide-binding protein G(s) subunit alpha isoforms XLas — human protein (gene GNAS, 1037 amino acids, UniProt Q5JWF2). AlphaFold-predicted 3D structure; by default coloured by model confidence (blue = very high, orange = very low, typical of disordered regions).
Rap guanine nucleotide exchange factor 4 (RAPGEF4) — Rap guanine nucleotide exchange factor 4 — human protein (gene RAPGEF4, 1011 amino acids, UniProt Q8WZA2). AlphaFold-predicted 3D structure; by default coloured by model confidence (blue = very high, orange = very low, typical of disordered regions).
Stress-associated endoplasmic reticulum protein 1 (SERP1) — Stress-associated endoplasmic reticulum protein 1 — human protein (gene SERP1, 66 amino acids, UniProt Q9Y6X1). AlphaFold-predicted 3D structure; by default coloured by model confidence (blue = very high, orange = very low, typical of disordered regions).
Pro-FMRFamide-related neuropeptide FF (NPFF) — Pro-FMRFamide-related neuropeptide FF — human protein (gene NPFF, 113 amino acids, UniProt O15130). AlphaFold-predicted 3D structure; by default coloured by model confidence (blue = very high, orange = very low, typical of disordered regions).
High affinity cAMP-specific and IBMX-insensitive 3',5'-cyclic phosphodiesterase 8B (PDE8B) — High affinity cAMP-specific and IBMX-insensitive 3',5'-cyclic phosphodiesterase 8B — human protein (gene PDE8B, 885 amino acids, UniProt O95263). AlphaFold-predicted 3D structure; by default coloured by model confidence (blue = very high, orange = very low, typical of disordered regions).
Gastrin-releasing peptide (GRP) — Gastrin-releasing peptide — human protein (gene GRP, 148 amino acids, UniProt P07492). AlphaFold-predicted 3D structure; by default coloured by model confidence (blue = very high, orange = very low, typical of disordered regions).
Neurotensin/neuromedin N (NTS) — Neurotensin/neuromedin N — human protein (gene NTS, 170 amino acids, UniProt P30990). AlphaFold-predicted 3D structure; by default coloured by model confidence (blue = very high, orange = very low, typical of disordered regions).
Neuromedin-U (NMU) — Neuromedin-U — human protein (gene NMU, 174 amino acids, UniProt P48645). AlphaFold-predicted 3D structure; by default coloured by model confidence (blue = very high, orange = very low, typical of disordered regions).
3',5'-cyclic-AMP phosphodiesterase 4B (PDE4B) — 3',5'-cyclic-AMP phosphodiesterase 4B — human protein (gene PDE4B, 736 amino acids, UniProt Q07343). AlphaFold-predicted 3D structure; by default coloured by model confidence (blue = very high, orange = very low, typical of disordered regions).
cGMP-inhibited 3',5'-cyclic phosphodiesterase 3B (PDE3B) — cGMP-inhibited 3',5'-cyclic phosphodiesterase 3B — human protein (gene PDE3B, 1112 amino acids, UniProt Q13370). AlphaFold-predicted 3D structure; by default coloured by model confidence (blue = very high, orange = very low, typical of disordered regions).
Dual specificity calcium/calmodulin-dependent 3',5'-cyclic nucleotide phosphodiesterase 1C (PDE1C) — Dual specificity calcium/calmodulin-dependent 3',5'-cyclic nucleotide phosphodiesterase 1C — human protein (gene PDE1C, 709 amino acids, UniProt Q14123). AlphaFold-predicted 3D structure; by default coloured by model confidence (blue = very high, orange = very low, typical of disordered regions).
CREB-regulated transcription coactivator 2 (CRTC2) — CREB-regulated transcription coactivator 2 — human protein (gene CRTC2, 693 amino acids, UniProt Q53ET0). AlphaFold-predicted 3D structure; by default coloured by model confidence (blue = very high, orange = very low, typical of disordered regions).
Germinal center-associated signaling and motility protein (GCSAM) — Germinal center-associated signaling and motility protein — human protein (gene GCSAM, 178 amino acids, UniProt Q8N6F7). AlphaFold-predicted 3D structure; by default coloured by model confidence (blue = very high, orange = very low, typical of disordered regions).
Adiponectin receptor protein 1 (ADIPOR1) — Adiponectin receptor protein 1 — human protein (gene ADIPOR1, 375 amino acids, UniProt Q96A54). AlphaFold-predicted 3D structure; by default coloured by model confidence (blue = very high, orange = very low, typical of disordered regions).
Neuromedin-U receptor 2 (NMUR2) — Neuromedin-U receptor 2 — human protein (gene NMUR2, 415 amino acids, UniProt Q9GZQ4). AlphaFold-predicted 3D structure; by default coloured by model confidence (blue = very high, orange = very low, typical of disordered regions).
Neuromedin-U receptor 1 (NMUR1) — Neuromedin-U receptor 1 — human protein (gene NMUR1, 426 amino acids, UniProt Q9HB89). AlphaFold-predicted 3D structure; by default coloured by model confidence (blue = very high, orange = very low, typical of disordered regions).
Transcription factor 7-like 2 (TCF7L2) — Transcription factor 7-like 2 — human protein (gene TCF7L2, 619 amino acids, UniProt Q9NQB0). AlphaFold-predicted 3D structure; by default coloured by model confidence (blue = very high, orange = very low, typical of disordered regions).
cAMP and cAMP-inhibited cGMP 3',5'-cyclic phosphodiesterase 10A (PDE10A) — cAMP and cAMP-inhibited cGMP 3',5'-cyclic phosphodiesterase 10A — human protein (gene PDE10A, 1055 amino acids, UniProt Q9Y233). AlphaFold-predicted 3D structure; by default coloured by model confidence (blue = very high, orange = very low, typical of disordered regions).
Insulin-like growth factor-binding protein 1 (IGFBP1) — Insulin-like growth factor-binding protein 1 — human protein (gene IGFBP1, 259 amino acids, UniProt P08833). AlphaFold-predicted 3D structure; by default coloured by model confidence (blue = very high, orange = very low, typical of disordered regions).
Adiponectin receptor protein 2 (ADIPOR2) — Adiponectin receptor protein 2 — human protein (gene ADIPOR2, 386 amino acids, UniProt Q86V24). AlphaFold-predicted 3D structure; by default coloured by model confidence (blue = very high, orange = very low, typical of disordered regions).
Beta-klotho (KLB) — Beta-klotho — human protein (gene KLB, 1044 amino acids, UniProt Q86Z14). AlphaFold-predicted 3D structure; by default coloured by model confidence (blue = very high, orange = very low, typical of disordered regions).
Carnitine O-palmitoyltransferase 1, muscle isoform (CPT1B) — Carnitine O-palmitoyltransferase 1, muscle isoform — human protein (gene CPT1B, 772 amino acids, UniProt Q92523). AlphaFold-predicted 3D structure; by default coloured by model confidence (blue = very high, orange = very low, typical of disordered regions).
Calcium/calmodulin-dependent protein kinase kinase 2 (CAMKK2) — Calcium/calmodulin-dependent protein kinase kinase 2 — human protein (gene CAMKK2, 588 amino acids, UniProt Q96RR4). AlphaFold-predicted 3D structure; by default coloured by model confidence (blue = very high, orange = very low, typical of disordered regions).
Relaxin receptor 1 (RXFP1) — Relaxin receptor 1 — human protein (gene RXFP1, 757 amino acids, UniProt Q9HBX9). AlphaFold-predicted 3D structure; by default coloured by model confidence (blue = very high, orange = very low, typical of disordered regions).
5'-AMP-activated protein kinase subunit beta-1 (PRKAB1) — 5'-AMP-activated protein kinase subunit beta-1 — human protein (gene PRKAB1, 270 amino acids, UniProt Q9Y478). AlphaFold-predicted 3D structure; by default coloured by model confidence (blue = very high, orange = very low, typical of disordered regions).
VPS10 domain-containing receptor SorCS1 (SORCS1) — VPS10 domain-containing receptor SorCS1 — human protein (gene SORCS1, 1168 amino acids, UniProt Q8WY21). AlphaFold-predicted 3D structure; by default coloured by model confidence (blue = very high, orange = very low, typical of disordered regions).
VPS10 domain-containing receptor SorCS2 (SORCS2) — VPS10 domain-containing receptor SorCS2 — human protein (gene SORCS2, 1159 amino acids, UniProt Q96PQ0). AlphaFold-predicted 3D structure; by default coloured by model confidence (blue = very high, orange = very low, typical of disordered regions).
VPS10 domain-containing receptor SorCS3 (SORCS3) — VPS10 domain-containing receptor SorCS3 — human protein (gene SORCS3, 1222 amino acids, UniProt Q9UPU3). AlphaFold-predicted 3D structure; by default coloured by model confidence (blue = very high, orange = very low, typical of disordered regions).
Glucagon-like peptide 2 receptor (GLP2R) — Glucagon-like peptide 2 receptor — human protein (gene GLP2R, 553 amino acids, UniProt O95838). AlphaFold-predicted 3D structure; by default coloured by model confidence (blue = very high, orange = very low, typical of disordered regions).
Glucose-dependent insulinotropic receptor (GPR119) — Glucose-dependent insulinotropic receptor — human protein (gene GPR119, 335 amino acids, UniProt Q8TDV5). AlphaFold-predicted 3D structure; by default coloured by model confidence (blue = very high, orange = very low, typical of disordered regions).
Relaxin-3 receptor 2 (RXFP4) — Relaxin-3 receptor 2 — human protein (gene RXFP4, 374 amino acids, UniProt Q8TDU9). AlphaFold-predicted 3D structure; by default coloured by model confidence (blue = very high, orange = very low, typical of disordered regions).
Galectin-related protein (LGALSL) — Galectin-related protein — human protein (gene LGALSL, 172 amino acids, UniProt Q3ZCW2). AlphaFold-predicted 3D structure; by default coloured by model confidence (blue = very high, orange = very low, typical of disordered regions).