Library › DNA & Proteins › Human proteins (AlphaFold) · Inflammasomes & pyroptosis

Human proteins (AlphaFold) · Inflammasomes & pyroptosis: 47 3D models

DNA, RNA, nucleic-acid drugs, gene editing, proteins and 300+ real PDB structures (real sizes 1–100 nm). Each one is a ready-made 3D model you can turn, recolour and place in a figure — open BioDiorama and type its name in the Library search.

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Interleukin-1 receptor antagonist protein (IL1RN) — Interleukin-1 receptor antagonist protein — human protein (gene IL1RN, 177 amino acids, UniProt P18510). AlphaFold-predicted 3D structure; by default coloured by model confidence (blue = very high, orange = very low, typical of disordered regions).
NACHT, LRR and PYD domains-containing protein 12 (NLRP12) — NACHT, LRR and PYD domains-containing protein 12 — human protein (gene NLRP12, 1061 amino acids, UniProt P59046). AlphaFold-predicted 3D structure; by default coloured by model confidence (blue = very high, orange = very low, typical of disordered regions).
NACHT, LRR and PYD domains-containing protein 5 (NLRP5) — NACHT, LRR and PYD domains-containing protein 5 — human protein (gene NLRP5, 1200 amino acids, UniProt P59047). AlphaFold-predicted 3D structure; by default coloured by model confidence (blue = very high, orange = very low, typical of disordered regions).
NACHT, LRR and PYD domains-containing protein 9 (NLRP9) — NACHT, LRR and PYD domains-containing protein 9 — human protein (gene NLRP9, 991 amino acids, UniProt Q7RTR0). AlphaFold-predicted 3D structure; by default coloured by model confidence (blue = very high, orange = very low, typical of disordered regions).
NACHT, LRR and PYD domains-containing protein 10 (NLRP10) — NACHT, LRR and PYD domains-containing protein 10 — human protein (gene NLRP10, 655 amino acids, UniProt Q86W26). AlphaFold-predicted 3D structure; by default coloured by model confidence (blue = very high, orange = very low, typical of disordered regions).
Gasdermin-B (GSDMB) — Gasdermin-B — human protein (gene GSDMB, 416 amino acids, UniProt Q8TAX9). AlphaFold-predicted 3D structure; by default coloured by model confidence (blue = very high, orange = very low, typical of disordered regions).
Serine/threonine-protein kinase Nek7 (NEK7) — Serine/threonine-protein kinase Nek7 — human protein (gene NEK7, 302 amino acids, UniProt Q8TDX7). AlphaFold-predicted 3D structure; by default coloured by model confidence (blue = very high, orange = very low, typical of disordered regions).
NACHT, LRR and PYD domains-containing protein 7 (NLRP7) — NACHT, LRR and PYD domains-containing protein 7 — human protein (gene NLRP7, 980 amino acids, UniProt Q8WX94). AlphaFold-predicted 3D structure; by default coloured by model confidence (blue = very high, orange = very low, typical of disordered regions).
Pyrin domain-containing protein 1 (PYDC1) — Pyrin domain-containing protein 1 — human protein (gene PYDC1, 89 amino acids, UniProt Q8WXC3). AlphaFold-predicted 3D structure; by default coloured by model confidence (blue = very high, orange = very low, typical of disordered regions).
NACHT, LRR and PYD domains-containing protein 4 (NLRP4) — NACHT, LRR and PYD domains-containing protein 4 — human protein (gene NLRP4, 994 amino acids, UniProt Q96MN2). AlphaFold-predicted 3D structure; by default coloured by model confidence (blue = very high, orange = very low, typical of disordered regions).
NACHT, LRR and PYD domains-containing protein 3 (NLRP3) — NACHT, LRR and PYD domains-containing protein 3 — human protein (gene NLRP3, 1036 amino acids, UniProt Q96P20). AlphaFold-predicted 3D structure; by default coloured by model confidence (blue = very high, orange = very low, typical of disordered regions).
Gasdermin-A (GSDMA) — Gasdermin-A — human protein (gene GSDMA, 445 amino acids, UniProt Q96QA5). AlphaFold-predicted 3D structure; by default coloured by model confidence (blue = very high, orange = very low, typical of disordered regions).
Protein SCAF11 (SCAF11) — Protein SCAF11 — human protein (gene SCAF11, 1463 amino acids, UniProt Q99590). AlphaFold-predicted 3D structure; by default coloured by model confidence (blue = very high, orange = very low, typical of disordered regions).
Gasdermin-C (GSDMC) — Gasdermin-C — human protein (gene GSDMC, 508 amino acids, UniProt Q9BYG8). AlphaFold-predicted 3D structure; by default coloured by model confidence (blue = very high, orange = very low, typical of disordered regions).
NACHT, LRR and PYD domains-containing protein 1 (NLRP1) — NACHT, LRR and PYD domains-containing protein 1 — human protein (gene NLRP1, 1473 amino acids, UniProt Q9C000). AlphaFold-predicted 3D structure; by default coloured by model confidence (blue = very high, orange = very low, typical of disordered regions).
NLR family CARD domain-containing protein 4 (NLRC4) — NLR family CARD domain-containing protein 4 — human protein (gene NLRC4, 1024 amino acids, UniProt Q9NPP4). AlphaFold-predicted 3D structure; by default coloured by model confidence (blue = very high, orange = very low, typical of disordered regions).
NACHT, LRR and PYD domains-containing protein 2 (NLRP2) — NACHT, LRR and PYD domains-containing protein 2 — human protein (gene NLRP2, 1062 amino acids, UniProt Q9NX02). AlphaFold-predicted 3D structure; by default coloured by model confidence (blue = very high, orange = very low, typical of disordered regions).
Caspase recruitment domain-containing protein 8 (CARD8) — Caspase recruitment domain-containing protein 8 — human protein (gene CARD8, 537 amino acids, UniProt Q9Y2G2). AlphaFold-predicted 3D structure; by default coloured by model confidence (blue = very high, orange = very low, typical of disordered regions).
Interleukin-18-binding protein (IL18BP) — Interleukin-18-binding protein — human protein (gene IL18BP, 194 amino acids, UniProt O95998). AlphaFold-predicted 3D structure; by default coloured by model confidence (blue = very high, orange = very low, typical of disordered regions).
Interleukin-18 receptor 1 (IL18R1) — Interleukin-18 receptor 1 — human protein (gene IL18R1, 541 amino acids, UniProt Q13478). AlphaFold-predicted 3D structure; by default coloured by model confidence (blue = very high, orange = very low, typical of disordered regions).
Caspase recruitment domain-containing protein 16 (CARD16) — Caspase recruitment domain-containing protein 16 — human protein (gene CARD16, 197 amino acids, UniProt Q5EG05). AlphaFold-predicted 3D structure; by default coloured by model confidence (blue = very high, orange = very low, typical of disordered regions).
Inactive caspase-12 (CASP12) — Inactive caspase-12 — human protein (gene CASP12, 341 amino acids, UniProt Q6UXS9). AlphaFold-predicted 3D structure; by default coloured by model confidence (blue = very high, orange = very low, typical of disordered regions).
NLR family CARD domain-containing protein 3 (NLRC3) — NLR family CARD domain-containing protein 3 — human protein (gene NLRC3, 1065 amino acids, UniProt Q7RTR2). AlphaFold-predicted 3D structure; by default coloured by model confidence (blue = very high, orange = very low, typical of disordered regions).
Dipeptidyl peptidase 9 (DPP9) — Dipeptidyl peptidase 9 — human protein (gene DPP9, 863 amino acids, UniProt Q86TI2). AlphaFold-predicted 3D structure; by default coloured by model confidence (blue = very high, orange = very low, typical of disordered regions).
NLR family member X1 (NLRX1) — NLR family member X1 — human protein (gene NLRX1, 975 amino acids, UniProt Q86UT6). AlphaFold-predicted 3D structure; by default coloured by model confidence (blue = very high, orange = very low, typical of disordered regions).
Protein NLRC5 (NLRC5) — Protein NLRC5 — human protein (gene NLRC5, 1866 amino acids, UniProt Q86WI3). AlphaFold-predicted 3D structure; by default coloured by model confidence (blue = very high, orange = very low, typical of disordered regions).
Atlastin-1 (ATL1) — Atlastin-1 — human protein (gene ATL1, 558 amino acids, UniProt Q8WXF7). AlphaFold-predicted 3D structure; by default coloured by model confidence (blue = very high, orange = very low, typical of disordered regions).
Methylthioribulose-1-phosphate dehydratase (APIP) — Methylthioribulose-1-phosphate dehydratase — human protein (gene APIP, 242 amino acids, UniProt Q96GX9). AlphaFold-predicted 3D structure; by default coloured by model confidence (blue = very high, orange = very low, typical of disordered regions).
Guanylate-binding protein 5 (GBP5) — Guanylate-binding protein 5 — human protein (gene GBP5, 586 amino acids, UniProt Q96PP8). AlphaFold-predicted 3D structure; by default coloured by model confidence (blue = very high, orange = very low, typical of disordered regions).
Guanylate-binding protein 4 (GBP4) — Guanylate-binding protein 4 — human protein (gene GBP4, 640 amino acids, UniProt Q96PP9). AlphaFold-predicted 3D structure; by default coloured by model confidence (blue = very high, orange = very low, typical of disordered regions).
Myeloid differentiation primary response protein MyD88 (MYD88) — Myeloid differentiation primary response protein MyD88 — human protein (gene MYD88, 296 amino acids, UniProt Q99836). AlphaFold-predicted 3D structure; by default coloured by model confidence (blue = very high, orange = very low, typical of disordered regions).
Plakophilin-2 (PKP2) — Plakophilin-2 — human protein (gene PKP2, 881 amino acids, UniProt Q99959). AlphaFold-predicted 3D structure; by default coloured by model confidence (blue = very high, orange = very low, typical of disordered regions).
Palmitoyltransferase ZDHHC5 (ZDHHC5) — Palmitoyltransferase ZDHHC5 — human protein (gene ZDHHC5, 715 amino acids, UniProt Q9C0B5). AlphaFold-predicted 3D structure; by default coloured by model confidence (blue = very high, orange = very low, typical of disordered regions).
Guanylate-binding protein 3 (GBP3) — Guanylate-binding protein 3 — human protein (gene GBP3, 595 amino acids, UniProt Q9H0R5). AlphaFold-predicted 3D structure; by default coloured by model confidence (blue = very high, orange = very low, typical of disordered regions).
Z-DNA-binding protein 1 (ZBP1) — Z-DNA-binding protein 1 — human protein (gene ZBP1, 429 amino acids, UniProt Q9H171). AlphaFold-predicted 3D structure; by default coloured by model confidence (blue = very high, orange = very low, typical of disordered regions).
ATP-dependent RNA helicase DHX33 (DHX33) — ATP-dependent RNA helicase DHX33 — human protein (gene DHX33, 707 amino acids, UniProt Q9H6R0). AlphaFold-predicted 3D structure; by default coloured by model confidence (blue = very high, orange = very low, typical of disordered regions).
Nucleotide-binding oligomerization domain-containing protein 2 (NOD2) — Nucleotide-binding oligomerization domain-containing protein 2 — human protein (gene NOD2, 1040 amino acids, UniProt Q9HC29). AlphaFold-predicted 3D structure; by default coloured by model confidence (blue = very high, orange = very low, typical of disordered regions).
Interleukin-1 receptor accessory protein (IL1RAP) — Interleukin-1 receptor accessory protein — human protein (gene IL1RAP, 570 amino acids, UniProt Q9NPH3). AlphaFold-predicted 3D structure; by default coloured by model confidence (blue = very high, orange = very low, typical of disordered regions).
Mitogen-activated protein kinase kinase kinase 20 (MAP3K20) — Mitogen-activated protein kinase kinase kinase 20 — human protein (gene MAP3K20, 800 amino acids, UniProt Q9NYL2). AlphaFold-predicted 3D structure; by default coloured by model confidence (blue = very high, orange = very low, typical of disordered regions).
Triggering receptor expressed on myeloid cells 2 (TREM2) — Triggering receptor expressed on myeloid cells 2 — human protein (gene TREM2, 230 amino acids, UniProt Q9NZC2). AlphaFold-predicted 3D structure; by default coloured by model confidence (blue = very high, orange = very low, typical of disordered regions).
Nucleotide-binding oligomerization domain-containing protein 1 (NOD1) — Nucleotide-binding oligomerization domain-containing protein 1 — human protein (gene NOD1, 953 amino acids, UniProt Q9Y239). AlphaFold-predicted 3D structure; by default coloured by model confidence (blue = very high, orange = very low, typical of disordered regions).
Palmitoyltransferase ZDHHC9 (ZDHHC9) — Palmitoyltransferase ZDHHC9 — human protein (gene ZDHHC9, 364 amino acids, UniProt Q9Y397). AlphaFold-predicted 3D structure; by default coloured by model confidence (blue = very high, orange = very low, typical of disordered regions).
NACHT, LRR and PYD domains-containing protein 11 (NLRP11) — NACHT, LRR and PYD domains-containing protein 11 — human protein (gene NLRP11, 1033 amino acids, UniProt P59045). AlphaFold-predicted 3D structure; by default coloured by model confidence (blue = very high, orange = very low, typical of disordered regions).
Pejvakin (PJVK) — Pejvakin — human protein (gene PJVK, 352 amino acids, UniProt Q0ZLH3). AlphaFold-predicted 3D structure; by default coloured by model confidence (blue = very high, orange = very low, typical of disordered regions).
NACHT, LRR and PYD domains-containing protein 8 (NLRP8) — NACHT, LRR and PYD domains-containing protein 8 — human protein (gene NLRP8, 1048 amino acids, UniProt Q86W28). AlphaFold-predicted 3D structure; by default coloured by model confidence (blue = very high, orange = very low, typical of disordered regions).
Caspase recruitment domain-containing protein 18 (CARD18) — Caspase recruitment domain-containing protein 18 — human protein (gene CARD18, 90 amino acids, UniProt P57730). AlphaFold-predicted 3D structure; by default coloured by model confidence (blue = very high, orange = very low, typical of disordered regions).
NACHT, LRR and PYD domains-containing protein 13 (NLRP13) — NACHT, LRR and PYD domains-containing protein 13 — human protein (gene NLRP13, 1043 amino acids, UniProt Q86W25). AlphaFold-predicted 3D structure; by default coloured by model confidence (blue = very high, orange = very low, typical of disordered regions).