Library › DNA & Proteins › Human proteins (AlphaFold) · Metabolic enzymes

Human proteins (AlphaFold) · Metabolic enzymes: 300 3D models

DNA, RNA, nucleic-acid drugs, gene editing, proteins and 300+ real PDB structures (real sizes 1–100 nm). Each one is a ready-made 3D model you can turn, recolour and place in a figure — open BioDioRama and type its name in the Library search.

Open the 3D Studio

2-hydroxyacyl-CoA lyase 2 (HACL2) — 2-hydroxyacyl-CoA lyase 2 — human protein (gene HACL2, 632 amino acids, UniProt A1L0T0). AlphaFold-predicted 3D structure; by default coloured by model confidence (blue = very high, orange = very low, typical of disordered regions).
Very long chain fatty acid elongase 7 (ELOVL7) — Very long chain fatty acid elongase 7 — human protein (gene ELOVL7, 281 amino acids, UniProt A1L3X0). AlphaFold-predicted 3D structure; by default coloured by model confidence (blue = very high, orange = very low, typical of disordered regions).
Plasmanylethanolamine desaturase 1 (PEDS1) — Plasmanylethanolamine desaturase 1 — human protein (gene PEDS1, 270 amino acids, UniProt A5PLL7). AlphaFold-predicted 3D structure; by default coloured by model confidence (blue = very high, orange = very low, typical of disordered regions).
Very-long-chain (HACD1) — Very-long-chain — human protein (gene HACD1, 288 amino acids, UniProt B0YJ81). AlphaFold-predicted 3D structure; by default coloured by model confidence (blue = very high, orange = very low, typical of disordered regions).
Aldo-keto reductase family 1 member B15 (AKR1B15) — Aldo-keto reductase family 1 member B15 — human protein (gene AKR1B15, 316 amino acids, UniProt C9JRZ8). AlphaFold-predicted 3D structure; by default coloured by model confidence (blue = very high, orange = very low, typical of disordered regions).
Alkyldihydroxyacetonephosphate synthase, peroxisomal (AGPS) — Alkyldihydroxyacetonephosphate synthase, peroxisomal — human protein (gene AGPS, 658 amino acids, UniProt O00116). AlphaFold-predicted 3D structure; by default coloured by model confidence (blue = very high, orange = very low, typical of disordered regions).
Cytosolic acyl coenzyme A thioester hydrolase (ACOT7) — Cytosolic acyl coenzyme A thioester hydrolase — human protein (gene ACOT7, 380 amino acids, UniProt O00154). AlphaFold-predicted 3D structure; by default coloured by model confidence (blue = very high, orange = very low, typical of disordered regions).
Sulfotransferase 2B1 (SULT2B1) — Sulfotransferase 2B1 — human protein (gene SULT2B1, 365 amino acids, UniProt O00204). AlphaFold-predicted 3D structure; by default coloured by model confidence (blue = very high, orange = very low, typical of disordered regions).
Cocaine esterase (CES2) — Cocaine esterase — human protein (gene CES2, 559 amino acids, UniProt O00748). AlphaFold-predicted 3D structure; by default coloured by model confidence (blue = very high, orange = very low, typical of disordered regions).
Acetyl-CoA carboxylase 2 (ACACB) — Acetyl-CoA carboxylase 2 — human protein (gene ACACB, 2458 amino acids, UniProt O00763). AlphaFold-predicted 3D structure; by default coloured by model confidence (blue = very high, orange = very low, typical of disordered regions).
Stearoyl-CoA desaturase (SCD) — Stearoyl-CoA desaturase — human protein (gene SCD, 359 amino acids, UniProt O00767). AlphaFold-predicted 3D structure; by default coloured by model confidence (blue = very high, orange = very low, typical of disordered regions).
Phospholipid phosphatase 1 (PLPP1) — Phospholipid phosphatase 1 — human protein (gene PLPP1, 284 amino acids, UniProt O14494). AlphaFold-predicted 3D structure; by default coloured by model confidence (blue = very high, orange = very low, typical of disordered regions).
Phospholipid phosphatase 3 (PLPP3) — Phospholipid phosphatase 3 — human protein (gene PLPP3, 311 amino acids, UniProt O14495). AlphaFold-predicted 3D structure; by default coloured by model confidence (blue = very high, orange = very low, typical of disordered regions).
Glyceraldehyde-3-phosphate dehydrogenase, testis-specific (GAPDHS) — Glyceraldehyde-3-phosphate dehydrogenase, testis-specific — human protein (gene GAPDHS, 408 amino acids, UniProt O14556). AlphaFold-predicted 3D structure; by default coloured by model confidence (blue = very high, orange = very low, typical of disordered regions).
Acyl carrier protein, mitochondrial (NDUFAB1) — Acyl carrier protein, mitochondrial — human protein (gene NDUFAB1, 156 amino acids, UniProt O14561). AlphaFold-predicted 3D structure; by default coloured by model confidence (blue = very high, orange = very low, typical of disordered regions).
Prostaglandin E synthase (PTGES) — Prostaglandin E synthase — human protein (gene PTGES, 152 amino acids, UniProt O14684). AlphaFold-predicted 3D structure; by default coloured by model confidence (blue = very high, orange = very low, typical of disordered regions).
Acyl-coenzyme A thioesterase 8 (ACOT8) — Acyl-coenzyme A thioesterase 8 — human protein (gene ACOT8, 319 amino acids, UniProt O14734). AlphaFold-predicted 3D structure; by default coloured by model confidence (blue = very high, orange = very low, typical of disordered regions).
CDP-diacylglycerol--inositol 3-phosphatidyltransferase (CDIPT) — CDP-diacylglycerol--inositol 3-phosphatidyltransferase — human protein (gene CDIPT, 213 amino acids, UniProt O14735). AlphaFold-predicted 3D structure; by default coloured by model confidence (blue = very high, orange = very low, typical of disordered regions).
17-beta-hydroxysteroid dehydrogenase type 6 (HSD17B6) — 17-beta-hydroxysteroid dehydrogenase type 6 — human protein (gene HSD17B6, 317 amino acids, UniProt O14756). AlphaFold-predicted 3D structure; by default coloured by model confidence (blue = very high, orange = very low, typical of disordered regions).
Apolipoprotein L1 (APOL1) — Apolipoprotein L1 — human protein (gene APOL1, 398 amino acids, UniProt O14791). AlphaFold-predicted 3D structure; by default coloured by model confidence (blue = very high, orange = very low, typical of disordered regions).
Glutathione S-transferase 3, mitochondrial (MGST3) — Glutathione S-transferase 3, mitochondrial — human protein (gene MGST3, 152 amino acids, UniProt O14880). AlphaFold-predicted 3D structure; by default coloured by model confidence (blue = very high, orange = very low, typical of disordered regions).
Phospholipase D2 (PLD2) — Phospholipase D2 — human protein (gene PLD2, 933 amino acids, UniProt O14939). AlphaFold-predicted 3D structure; by default coloured by model confidence (blue = very high, orange = very low, typical of disordered regions).
1-acyl-sn-glycerol-3-phosphate acyltransferase beta (AGPAT2) — 1-acyl-sn-glycerol-3-phosphate acyltransferase beta — human protein (gene AGPAT2, 278 amino acids, UniProt O15120). AlphaFold-predicted 3D structure; by default coloured by model confidence (blue = very high, orange = very low, typical of disordered regions).
Sphingolipid delta(4)-desaturase DES1 (DEGS1) — Sphingolipid delta(4)-desaturase DES1 — human protein (gene DEGS1, 323 amino acids, UniProt O15121). AlphaFold-predicted 3D structure; by default coloured by model confidence (blue = very high, orange = very low, typical of disordered regions).
Peroxisomal acyl-coenzyme A oxidase 3 (ACOX3) — Peroxisomal acyl-coenzyme A oxidase 3 — human protein (gene ACOX3, 700 amino acids, UniProt O15254). AlphaFold-predicted 3D structure; by default coloured by model confidence (blue = very high, orange = very low, typical of disordered regions).
Serine palmitoyltransferase 1 (SPTLC1) — Serine palmitoyltransferase 1 — human protein (gene SPTLC1, 473 amino acids, UniProt O15269). AlphaFold-predicted 3D structure; by default coloured by model confidence (blue = very high, orange = very low, typical of disordered regions).
Serine palmitoyltransferase 2 (SPTLC2) — Serine palmitoyltransferase 2 — human protein (gene SPTLC2, 562 amino acids, UniProt O15270). AlphaFold-predicted 3D structure; by default coloured by model confidence (blue = very high, orange = very low, typical of disordered regions).
Inositol polyphosphate 4-phosphatase type II (INPP4B) — Inositol polyphosphate 4-phosphatase type II — human protein (gene INPP4B, 924 amino acids, UniProt O15327). AlphaFold-predicted 3D structure; by default coloured by model confidence (blue = very high, orange = very low, typical of disordered regions).
Branched-chain-amino-acid aminotransferase, mitochondrial (BCAT2) — Branched-chain-amino-acid aminotransferase, mitochondrial — human protein (gene BCAT2, 392 amino acids, UniProt O15382). AlphaFold-predicted 3D structure; by default coloured by model confidence (blue = very high, orange = very low, typical of disordered regions).
Alpha-2,8-sialyltransferase 8E (ST8SIA5) — Alpha-2,8-sialyltransferase 8E — human protein (gene ST8SIA5, 376 amino acids, UniProt O15466). AlphaFold-predicted 3D structure; by default coloured by model confidence (blue = very high, orange = very low, typical of disordered regions).
Group 10 secretory phospholipase A2 (PLA2G10) — Group 10 secretory phospholipase A2 — human protein (gene PLA2G10, 165 amino acids, UniProt O15496). AlphaFold-predicted 3D structure; by default coloured by model confidence (blue = very high, orange = very low, typical of disordered regions).
Insulin-induced gene 1 protein (INSIG1) — Insulin-induced gene 1 protein — human protein (gene INSIG1, 277 amino acids, UniProt O15503). AlphaFold-predicted 3D structure; by default coloured by model confidence (blue = very high, orange = very low, typical of disordered regions).
25-hydroxyvitamin D-1 alpha hydroxylase, mitochondrial (CYP27B1) — 25-hydroxyvitamin D-1 alpha hydroxylase, mitochondrial — human protein (gene CYP27B1, 508 amino acids, UniProt O15528). AlphaFold-predicted 3D structure; by default coloured by model confidence (blue = very high, orange = very low, typical of disordered regions).
Cytochrome P450 26A1 (CYP26A1) — Cytochrome P450 26A1 — human protein (gene CYP26A1, 497 amino acids, UniProt O43174). AlphaFold-predicted 3D structure; by default coloured by model confidence (blue = very high, orange = very low, typical of disordered regions).
D-3-phosphoglycerate dehydrogenase (PHGDH) — D-3-phosphoglycerate dehydrogenase — human protein (gene PHGDH, 533 amino acids, UniProt O43175). AlphaFold-predicted 3D structure; by default coloured by model confidence (blue = very high, orange = very low, typical of disordered regions).
Beta-1,4-galactosyltransferase 5 (B4GALT5) — Beta-1,4-galactosyltransferase 5 — human protein (gene B4GALT5, 388 amino acids, UniProt O43286). AlphaFold-predicted 3D structure; by default coloured by model confidence (blue = very high, orange = very low, typical of disordered regions).
Polyphosphatidylinositol phosphatase SYNJ1 (SYNJ1) — Polyphosphatidylinositol phosphatase SYNJ1 — human protein (gene SYNJ1, 1573 amino acids, UniProt O43426). AlphaFold-predicted 3D structure; by default coloured by model confidence (blue = very high, orange = very low, typical of disordered regions).
Aflatoxin B1 aldehyde reductase member 2 (AKR7A2) — Aflatoxin B1 aldehyde reductase member 2 — human protein (gene AKR7A2, 359 amino acids, UniProt O43488). AlphaFold-predicted 3D structure; by default coloured by model confidence (blue = very high, orange = very low, typical of disordered regions).
Carbohydrate sulfotransferase 10 (CHST10) — Carbohydrate sulfotransferase 10 — human protein (gene CHST10, 356 amino acids, UniProt O43529). AlphaFold-predicted 3D structure; by default coloured by model confidence (blue = very high, orange = very low, typical of disordered regions).
Phospholipid phosphatase 2 (PLPP2) — Phospholipid phosphatase 2 — human protein (gene PLPP2, 288 amino acids, UniProt O43688). AlphaFold-predicted 3D structure; by default coloured by model confidence (blue = very high, orange = very low, typical of disordered regions).
5'-AMP-activated protein kinase subunit beta-2 (PRKAB2) — 5'-AMP-activated protein kinase subunit beta-2 — human protein (gene PRKAB2, 272 amino acids, UniProt O43741). AlphaFold-predicted 3D structure; by default coloured by model confidence (blue = very high, orange = very low, typical of disordered regions).
Beta-1,3-galactosyltransferase 2 (B3GALT2) — Beta-1,3-galactosyltransferase 2 — human protein (gene B3GALT2, 422 amino acids, UniProt O43825). AlphaFold-predicted 3D structure; by default coloured by model confidence (blue = very high, orange = very low, typical of disordered regions).
Isocitrate dehydrogenase [NAD] subunit beta, mitochondrial (IDH3B) — Isocitrate dehydrogenase [NAD] subunit beta, mitochondrial — human protein (gene IDH3B, 385 amino acids, UniProt O43837). AlphaFold-predicted 3D structure; by default coloured by model confidence (blue = very high, orange = very low, typical of disordered regions).
Aldo-keto reductase family 1 member B10 (AKR1B10) — Aldo-keto reductase family 1 member B10 — human protein (gene AKR1B10, 316 amino acids, UniProt O60218). AlphaFold-predicted 3D structure; by default coloured by model confidence (blue = very high, orange = very low, typical of disordered regions).
Perilipin-1 (PLIN1) — Perilipin-1 — human protein (gene PLIN1, 522 amino acids, UniProt O60240). AlphaFold-predicted 3D structure; by default coloured by model confidence (blue = very high, orange = very low, typical of disordered regions).
Long-chain-fatty-acid--CoA ligase 4 (ACSL4) — Long-chain-fatty-acid--CoA ligase 4 — human protein (gene ACSL4, 711 amino acids, UniProt O60488). AlphaFold-predicted 3D structure; by default coloured by model confidence (blue = very high, orange = very low, typical of disordered regions).
Beta-1,4-galactosyltransferase 3 (B4GALT3) — Beta-1,4-galactosyltransferase 3 — human protein (gene B4GALT3, 393 amino acids, UniProt O60512). AlphaFold-predicted 3D structure; by default coloured by model confidence (blue = very high, orange = very low, typical of disordered regions).
Beta-1,4-galactosyltransferase 4 (B4GALT4) — Beta-1,4-galactosyltransferase 4 — human protein (gene B4GALT4, 344 amino acids, UniProt O60513). AlphaFold-predicted 3D structure; by default coloured by model confidence (blue = very high, orange = very low, typical of disordered regions).
UDP-glucuronosyltransferase 1A9 (UGT1A9) — UDP-glucuronosyltransferase 1A9 — human protein (gene UGT1A9, 530 amino acids, UniProt O60656). AlphaFold-predicted 3D structure; by default coloured by model confidence (blue = very high, orange = very low, typical of disordered regions).
85/88 kDa calcium-independent phospholipase A2 (PLA2G6) — 85/88 kDa calcium-independent phospholipase A2 — human protein (gene PLA2G6, 806 amino acids, UniProt O60733). AlphaFold-predicted 3D structure; by default coloured by model confidence (blue = very high, orange = very low, typical of disordered regions).
Hematopoietic prostaglandin D synthase (HPGDS) — Hematopoietic prostaglandin D synthase — human protein (gene HPGDS, 199 amino acids, UniProt O60760). AlphaFold-predicted 3D structure; by default coloured by model confidence (blue = very high, orange = very low, typical of disordered regions).
Sphingomyelin phosphodiesterase 2 (SMPD2) — Sphingomyelin phosphodiesterase 2 — human protein (gene SMPD2, 423 amino acids, UniProt O60906). AlphaFold-predicted 3D structure; by default coloured by model confidence (blue = very high, orange = very low, typical of disordered regions).
1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase eta-2 (PLCH2) — 1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase eta-2 — human protein (gene PLCH2, 1416 amino acids, UniProt O75038). AlphaFold-predicted 3D structure; by default coloured by model confidence (blue = very high, orange = very low, typical of disordered regions).
Arachidonate 12-lipoxygenase, 12R-type (ALOX12B) — Arachidonate 12-lipoxygenase, 12R-type — human protein (gene ALOX12B, 701 amino acids, UniProt O75342). AlphaFold-predicted 3D structure; by default coloured by model confidence (blue = very high, orange = very low, typical of disordered regions).
Citrate synthase, mitochondrial (CS) — Citrate synthase, mitochondrial — human protein (gene CS, 466 amino acids, UniProt O75390). AlphaFold-predicted 3D structure; by default coloured by model confidence (blue = very high, orange = very low, typical of disordered regions).
Retinol dehydrogenase 16 (RDH16) — Retinol dehydrogenase 16 — human protein (gene RDH16, 317 amino acids, UniProt O75452). AlphaFold-predicted 3D structure; by default coloured by model confidence (blue = very high, orange = very low, typical of disordered regions).
Erlin-1 (ERLIN1) — Erlin-1 — human protein (gene ERLIN1, 348 amino acids, UniProt O75477). AlphaFold-predicted 3D structure; by default coloured by model confidence (blue = very high, orange = very low, typical of disordered regions).
Acyl-protein thioesterase 1 (LYPLA1) — Acyl-protein thioesterase 1 — human protein (gene LYPLA1, 230 amino acids, UniProt O75608). AlphaFold-predicted 3D structure; by default coloured by model confidence (blue = very high, orange = very low, typical of disordered regions).
UDP-GalNAc:beta-1,3-N-acetylgalactosaminyltransferase 1 (B3GALNT1) — UDP-GalNAc:beta-1,3-N-acetylgalactosaminyltransferase 1 — human protein (gene B3GALNT1, 331 amino acids, UniProt O75752). AlphaFold-predicted 3D structure; by default coloured by model confidence (blue = very high, orange = very low, typical of disordered regions).
UDP-glucuronosyltransferase 2B17 (UGT2B17) — UDP-glucuronosyltransferase 2B17 — human protein (gene UGT2B17, 530 amino acids, UniProt O75795). AlphaFold-predicted 3D structure; by default coloured by model confidence (blue = very high, orange = very low, typical of disordered regions).
Lathosterol oxidase (SC5D) — Lathosterol oxidase — human protein (gene SC5D, 299 amino acids, UniProt O75845). AlphaFold-predicted 3D structure; by default coloured by model confidence (blue = very high, orange = very low, typical of disordered regions).
Isocitrate dehydrogenase [NADP] cytoplasmic (IDH1) — Isocitrate dehydrogenase [NADP] cytoplasmic — human protein (gene IDH1, 414 amino acids, UniProt O75874). AlphaFold-predicted 3D structure; by default coloured by model confidence (blue = very high, orange = very low, typical of disordered regions).
Cytochrome P450 7B1 (CYP7B1) — Cytochrome P450 7B1 — human protein (gene CYP7B1, 506 amino acids, UniProt O75881). AlphaFold-predicted 3D structure; by default coloured by model confidence (blue = very high, orange = very low, typical of disordered regions).
Diacylglycerol O-acyltransferase 1 (DGAT1) — Diacylglycerol O-acyltransferase 1 — human protein (gene DGAT1, 488 amino acids, UniProt O75907). AlphaFold-predicted 3D structure; by default coloured by model confidence (blue = very high, orange = very low, typical of disordered regions).
Sterol O-acyltransferase 2 (SOAT2) — Sterol O-acyltransferase 2 — human protein (gene SOAT2, 522 amino acids, UniProt O75908). AlphaFold-predicted 3D structure; by default coloured by model confidence (blue = very high, orange = very low, typical of disordered regions).
Short-chain dehydrogenase/reductase 3 (DHRS3) — Short-chain dehydrogenase/reductase 3 — human protein (gene DHRS3, 302 amino acids, UniProt O75911). AlphaFold-predicted 3D structure; by default coloured by model confidence (blue = very high, orange = very low, typical of disordered regions).
Delta(14)-sterol reductase TM7SF2 (TM7SF2) — Delta(14)-sterol reductase TM7SF2 — human protein (gene TM7SF2, 418 amino acids, UniProt O76062). AlphaFold-predicted 3D structure; by default coloured by model confidence (blue = very high, orange = very low, typical of disordered regions).
Retinal dehydrogenase 2 (ALDH1A2) — Retinal dehydrogenase 2 — human protein (gene ALDH1A2, 518 amino acids, UniProt O94788). AlphaFold-predicted 3D structure; by default coloured by model confidence (blue = very high, orange = very low, typical of disordered regions).
Triacylglycerol hydrolase DDHD2 (DDHD2) — Triacylglycerol hydrolase DDHD2 — human protein (gene DDHD2, 711 amino acids, UniProt O94830). AlphaFold-predicted 3D structure; by default coloured by model confidence (blue = very high, orange = very low, typical of disordered regions).
Erlin-2 (ERLIN2) — Erlin-2 — human protein (gene ERLIN2, 339 amino acids, UniProt O94905). AlphaFold-predicted 3D structure; by default coloured by model confidence (blue = very high, orange = very low, typical of disordered regions).
Lecithin retinol acyltransferase (LRAT) — Lecithin retinol acyltransferase — human protein (gene LRAT, 230 amino acids, UniProt O95237). AlphaFold-predicted 3D structure; by default coloured by model confidence (blue = very high, orange = very low, typical of disordered regions).
Acyl-protein thioesterase 2 (LYPLA2) — Acyl-protein thioesterase 2 — human protein (gene LYPLA2, 231 amino acids, UniProt O95372). AlphaFold-predicted 3D structure; by default coloured by model confidence (blue = very high, orange = very low, typical of disordered regions).
Fatty acid CoA ligase Acsl3 (ACSL3) — Fatty acid CoA ligase Acsl3 — human protein (gene ACSL3, 720 amino acids, UniProt O95573). AlphaFold-predicted 3D structure; by default coloured by model confidence (blue = very high, orange = very low, typical of disordered regions).
Phosphatidate cytidylyltransferase 2 (CDS2) — Phosphatidate cytidylyltransferase 2 — human protein (gene CDS2, 445 amino acids, UniProt O95674). AlphaFold-predicted 3D structure; by default coloured by model confidence (blue = very high, orange = very low, typical of disordered regions).
Geranylgeranyl pyrophosphate synthase (GGPS1) — Geranylgeranyl pyrophosphate synthase — human protein (gene GGPS1, 300 amino acids, UniProt O95749). AlphaFold-predicted 3D structure; by default coloured by model confidence (blue = very high, orange = very low, typical of disordered regions).
Malonyl-CoA decarboxylase, mitochondrial (MLYCD) — Malonyl-CoA decarboxylase, mitochondrial — human protein (gene MLYCD, 493 amino acids, UniProt O95822). AlphaFold-predicted 3D structure; by default coloured by model confidence (blue = very high, orange = very low, typical of disordered regions).
Phosphatidylserine lipase ABHD16A (ABHD16A) — Phosphatidylserine lipase ABHD16A — human protein (gene ABHD16A, 558 amino acids, UniProt O95870). AlphaFold-predicted 3D structure; by default coloured by model confidence (blue = very high, orange = very low, typical of disordered regions).
Cholesterol 25-hydroxylase (CH25H) — Cholesterol 25-hydroxylase — human protein (gene CH25H, 272 amino acids, UniProt O95992). AlphaFold-predicted 3D structure; by default coloured by model confidence (blue = very high, orange = very low, typical of disordered regions).
Beta-1,3-galactosyltransferase 4 (B3GALT4) — Beta-1,3-galactosyltransferase 4 — human protein (gene B3GALT4, 378 amino acids, UniProt O96024). AlphaFold-predicted 3D structure; by default coloured by model confidence (blue = very high, orange = very low, typical of disordered regions).
All-trans-retinol dehydrogenase [NAD(+)] ADH1B (ADH1B) — All-trans-retinol dehydrogenase [NAD(+)] ADH1B — human protein (gene ADH1B, 375 amino acids, UniProt P00325). AlphaFold-predicted 3D structure; by default coloured by model confidence (blue = very high, orange = very low, typical of disordered regions).
Aldehyde dehydrogenase 1A1 (ALDH1A1) — Aldehyde dehydrogenase 1A1 — human protein (gene ALDH1A1, 501 amino acids, UniProt P00352). AlphaFold-predicted 3D structure; by default coloured by model confidence (blue = very high, orange = very low, typical of disordered regions).
NADH-cytochrome b5 reductase 3 (CYB5R3) — NADH-cytochrome b5 reductase 3 — human protein (gene CYB5R3, 301 amino acids, UniProt P00387). AlphaFold-predicted 3D structure; by default coloured by model confidence (blue = very high, orange = very low, typical of disordered regions).
Ornithine transcarbamylase, mitochondrial (OTC) — Ornithine transcarbamylase, mitochondrial — human protein (gene OTC, 354 amino acids, UniProt P00480). AlphaFold-predicted 3D structure; by default coloured by model confidence (blue = very high, orange = very low, typical of disordered regions).
Argininosuccinate synthase (ASS1) — Argininosuccinate synthase — human protein (gene ASS1, 412 amino acids, UniProt P00966). AlphaFold-predicted 3D structure; by default coloured by model confidence (blue = very high, orange = very low, typical of disordered regions).
Apolipoprotein A-I (APOA1) — Apolipoprotein A-I — human protein (gene APOA1, 267 amino acids, UniProt P02647). AlphaFold-predicted 3D structure; by default coloured by model confidence (blue = very high, orange = very low, typical of disordered regions).
Apolipoprotein C-II (APOC2) — Apolipoprotein C-II — human protein (gene APOC2, 101 amino acids, UniProt P02655). AlphaFold-predicted 3D structure; by default coloured by model confidence (blue = very high, orange = very low, typical of disordered regions).
Apolipoprotein C-III (APOC3) — Apolipoprotein C-III — human protein (gene APOC3, 99 amino acids, UniProt P02656). AlphaFold-predicted 3D structure; by default coloured by model confidence (blue = very high, orange = very low, typical of disordered regions).
3-hydroxy-3-methylglutaryl-coenzyme A reductase (HMGCR) — 3-hydroxy-3-methylglutaryl-coenzyme A reductase — human protein (gene HMGCR, 888 amino acids, UniProt P04035). AlphaFold-predicted 3D structure; by default coloured by model confidence (blue = very high, orange = very low, typical of disordered regions).
Phospholipase A2 (PLA2G1B) — Phospholipase A2 — human protein (gene PLA2G1B, 148 amino acids, UniProt P04054). AlphaFold-predicted 3D structure; by default coloured by model confidence (blue = very high, orange = very low, typical of disordered regions).
Lysosomal acid glucosylceramidase (GBA1) — Lysosomal acid glucosylceramidase — human protein (gene GBA1, 536 amino acids, UniProt P04062). AlphaFold-predicted 3D structure; by default coloured by model confidence (blue = very high, orange = very low, typical of disordered regions).
Tissue alpha-L-fucosidase (FUCA1) — Tissue alpha-L-fucosidase — human protein (gene FUCA1, 466 amino acids, UniProt P04066). AlphaFold-predicted 3D structure; by default coloured by model confidence (blue = very high, orange = very low, typical of disordered regions).
Fructose-bisphosphate aldolase A (ALDOA) — Fructose-bisphosphate aldolase A — human protein (gene ALDOA, 364 amino acids, UniProt P04075). AlphaFold-predicted 3D structure; by default coloured by model confidence (blue = very high, orange = very low, typical of disordered regions).
Colipase (CLPS) — Colipase — human protein (gene CLPS, 112 amino acids, UniProt P04118). AlphaFold-predicted 3D structure; by default coloured by model confidence (blue = very high, orange = very low, typical of disordered regions).
Phosphatidylcholine-sterol acyltransferase (LCAT) — Phosphatidylcholine-sterol acyltransferase — human protein (gene LCAT, 440 amino acids, UniProt P04180). AlphaFold-predicted 3D structure; by default coloured by model confidence (blue = very high, orange = very low, typical of disordered regions).
Argininosuccinate lyase (ASL) — Argininosuccinate lyase — human protein (gene ASL, 464 amino acids, UniProt P04424). AlphaFold-predicted 3D structure; by default coloured by model confidence (blue = very high, orange = very low, typical of disordered regions).
Cytochrome P450 1A1 (CYP1A1) — Cytochrome P450 1A1 — human protein (gene CYP1A1, 512 amino acids, UniProt P04798). AlphaFold-predicted 3D structure; by default coloured by model confidence (blue = very high, orange = very low, typical of disordered regions).
Steroid 17-alpha-hydroxylase/17,20 lyase (CYP17A1) — Steroid 17-alpha-hydroxylase/17,20 lyase — human protein (gene CYP17A1, 508 amino acids, UniProt P05093). AlphaFold-predicted 3D structure; by default coloured by model confidence (blue = very high, orange = very low, typical of disordered regions).
Cholesterol side-chain cleavage enzyme, mitochondrial (CYP11A1) — Cholesterol side-chain cleavage enzyme, mitochondrial — human protein (gene CYP11A1, 521 amino acids, UniProt P05108). AlphaFold-predicted 3D structure; by default coloured by model confidence (blue = very high, orange = very low, typical of disordered regions).
Propionyl-CoA carboxylase alpha chain, mitochondrial (PCCA) — Propionyl-CoA carboxylase alpha chain, mitochondrial — human protein (gene PCCA, 728 amino acids, UniProt P05165). AlphaFold-predicted 3D structure; by default coloured by model confidence (blue = very high, orange = very low, typical of disordered regions).
Cytochrome P450 1A2 (CYP1A2) — Cytochrome P450 1A2 — human protein (gene CYP1A2, 516 amino acids, UniProt P05177). AlphaFold-predicted 3D structure; by default coloured by model confidence (blue = very high, orange = very low, typical of disordered regions).
Cytochrome P450 2E1 (CYP2E1) — Cytochrome P450 2E1 — human protein (gene CYP2E1, 493 amino acids, UniProt P05181). AlphaFold-predicted 3D structure; by default coloured by model confidence (blue = very high, orange = very low, typical of disordered regions).
UDP-glucuronosyltransferase 2B4 (UGT2B4) — UDP-glucuronosyltransferase 2B4 — human protein (gene UGT2B4, 528 amino acids, UniProt P06133). AlphaFold-predicted 3D structure; by default coloured by model confidence (blue = very high, orange = very low, typical of disordered regions).
Alpha-galactosidase A (GLA) — Alpha-galactosidase A — human protein (gene GLA, 429 amino acids, UniProt P06280). AlphaFold-predicted 3D structure; by default coloured by model confidence (blue = very high, orange = very low, typical of disordered regions).
Beta-hexosaminidase subunit alpha (HEXA) — Beta-hexosaminidase subunit alpha — human protein (gene HEXA, 529 amino acids, UniProt P06865). AlphaFold-predicted 3D structure; by default coloured by model confidence (blue = very high, orange = very low, typical of disordered regions).
Gastric triacylglycerol lipase (LIPF) — Gastric triacylglycerol lipase — human protein (gene LIPF, 398 amino acids, UniProt P07098). AlphaFold-predicted 3D structure; by default coloured by model confidence (blue = very high, orange = very low, typical of disordered regions).
Epoxide hydrolase 1 (EPHX1) — Epoxide hydrolase 1 — human protein (gene EPHX1, 455 amino acids, UniProt P07099). AlphaFold-predicted 3D structure; by default coloured by model confidence (blue = very high, orange = very low, typical of disordered regions).
Glutathione peroxidase 1 (GPX1) — Glutathione peroxidase 1 — human protein (gene GPX1, 203 amino acids, UniProt P07203). AlphaFold-predicted 3D structure; by default coloured by model confidence (blue = very high, orange = very low, typical of disordered regions).
Prosaposin (PSAP) — Prosaposin — human protein (gene PSAP, 524 amino acids, UniProt P07602). AlphaFold-predicted 3D structure; by default coloured by model confidence (blue = very high, orange = very low, typical of disordered regions).
Beta-hexosaminidase subunit beta (HEXB) — Beta-hexosaminidase subunit beta — human protein (gene HEXB, 556 amino acids, UniProt P07686). AlphaFold-predicted 3D structure; by default coloured by model confidence (blue = very high, orange = very low, typical of disordered regions).
Bisphosphoglycerate mutase (BPGM) — Bisphosphoglycerate mutase — human protein (gene BPGM, 259 amino acids, UniProt P07738). AlphaFold-predicted 3D structure; by default coloured by model confidence (blue = very high, orange = very low, typical of disordered regions).
Asparagine synthetase [glutamine-hydrolyzing] (ASNS) — Asparagine synthetase [glutamine-hydrolyzing] — human protein (gene ASNS, 561 amino acids, UniProt P08243). AlphaFold-predicted 3D structure; by default coloured by model confidence (blue = very high, orange = very low, typical of disordered regions).
Glutathione S-transferase A1 (GSTA1) — Glutathione S-transferase A1 — human protein (gene GSTA1, 222 amino acids, UniProt P08263). AlphaFold-predicted 3D structure; by default coloured by model confidence (blue = very high, orange = very low, typical of disordered regions).
All-trans-retinol dehydrogenase [NAD(+)] ADH4 (ADH4) — All-trans-retinol dehydrogenase [NAD(+)] ADH4 — human protein (gene ADH4, 380 amino acids, UniProt P08319). AlphaFold-predicted 3D structure; by default coloured by model confidence (blue = very high, orange = very low, typical of disordered regions).
Pyruvate dehydrogenase E1 component subunit alpha, somatic form, mitochondrial (PDHA1) — Pyruvate dehydrogenase E1 component subunit alpha, somatic form, mitochondrial — human protein (gene PDHA1, 390 amino acids, UniProt P08559). AlphaFold-predicted 3D structure; by default coloured by model confidence (blue = very high, orange = very low, typical of disordered regions).
Cytochrome P450 3A4 (CYP3A4) — Cytochrome P450 3A4 — human protein (gene CYP3A4, 503 amino acids, UniProt P08684). AlphaFold-predicted 3D structure; by default coloured by model confidence (blue = very high, orange = very low, typical of disordered regions).
Steroid 21-hydroxylase (CYP21A2) — Steroid 21-hydroxylase — human protein (gene CYP21A2, 495 amino acids, UniProt P08686). AlphaFold-predicted 3D structure; by default coloured by model confidence (blue = very high, orange = very low, typical of disordered regions).
Steryl-sulfatase (STS) — Steryl-sulfatase — human protein (gene STS, 583 amino acids, UniProt P08842). AlphaFold-predicted 3D structure; by default coloured by model confidence (blue = very high, orange = very low, typical of disordered regions).
Monoacylglycerol lipase ABHD2 (ABHD2) — Monoacylglycerol lipase ABHD2 — human protein (gene ABHD2, 425 amino acids, UniProt P08910). AlphaFold-predicted 3D structure; by default coloured by model confidence (blue = very high, orange = very low, typical of disordered regions).
Gamma-enolase (ENO2) — Gamma-enolase — human protein (gene ENO2, 434 amino acids, UniProt P09104). AlphaFold-predicted 3D structure; by default coloured by model confidence (blue = very high, orange = very low, typical of disordered regions).
3-ketoacyl-CoA thiolase, peroxisomal (ACAA1) — 3-ketoacyl-CoA thiolase, peroxisomal — human protein (gene ACAA1, 424 amino acids, UniProt P09110). AlphaFold-predicted 3D structure; by default coloured by model confidence (blue = very high, orange = very low, typical of disordered regions).
Glutathione S-transferase P (GSTP1) — Glutathione S-transferase P — human protein (gene GSTP1, 210 amino acids, UniProt P09211). AlphaFold-predicted 3D structure; by default coloured by model confidence (blue = very high, orange = very low, typical of disordered regions).
Glutathione S-transferase Mu 1 (GSTM1) — Glutathione S-transferase Mu 1 — human protein (gene GSTM1, 218 amino acids, UniProt P09488). AlphaFold-predicted 3D structure; by default coloured by model confidence (blue = very high, orange = very low, typical of disordered regions).
Polyunsaturated fatty acid 5-lipoxygenase (ALOX5) — Polyunsaturated fatty acid 5-lipoxygenase — human protein (gene ALOX5, 674 amino acids, UniProt P09917). AlphaFold-predicted 3D structure; by default coloured by model confidence (blue = very high, orange = very low, typical of disordered regions).
Fructose-bisphosphate aldolase C (ALDOC) — Fructose-bisphosphate aldolase C — human protein (gene ALDOC, 364 amino acids, UniProt P09972). AlphaFold-predicted 3D structure; by default coloured by model confidence (blue = very high, orange = very low, typical of disordered regions).
Cytosolic phospholipase A2 beta (PLA2G4B) — Cytosolic phospholipase A2 beta — human protein (gene PLA2G4B, 781 amino acids, UniProt P0C869). AlphaFold-predicted 3D structure; by default coloured by model confidence (blue = very high, orange = very low, typical of disordered regions).
Sulfotransferase 1A3 (SULT1A3) — Sulfotransferase 1A3 — human protein (gene SULT1A3, 295 amino acids, UniProt P0DMM9). AlphaFold-predicted 3D structure; by default coloured by model confidence (blue = very high, orange = very low, typical of disordered regions).
Sulfotransferase 1A4 (SULT1A4) — Sulfotransferase 1A4 — human protein (gene SULT1A4, 295 amino acids, UniProt P0DMN0). AlphaFold-predicted 3D structure; by default coloured by model confidence (blue = very high, orange = very low, typical of disordered regions).
UDP-glucuronosyltransferase 2A1 (UGT2A1) — UDP-glucuronosyltransferase 2A1 — human protein (gene UGT2A1, 527 amino acids, UniProt P0DTE4). AlphaFold-predicted 3D structure; by default coloured by model confidence (blue = very high, orange = very low, typical of disordered regions).
UDP-glucuronosyltransferase 2A2 (UGT2A2) — UDP-glucuronosyltransferase 2A2 — human protein (gene UGT2A2, 536 amino acids, UniProt P0DTE5). AlphaFold-predicted 3D structure; by default coloured by model confidence (blue = very high, orange = very low, typical of disordered regions).
Adrenodoxin, mitochondrial (FDX1) — Adrenodoxin, mitochondrial — human protein (gene FDX1, 184 amino acids, UniProt P10109). AlphaFold-predicted 3D structure; by default coloured by model confidence (blue = very high, orange = very low, typical of disordered regions).
Dihydrolipoyllysine-residue acetyltransferase component of pyruvate dehydrogenase complex, mitochondrial (DLAT) — Dihydrolipoyllysine-residue acetyltransferase component of pyruvate dehydrogenase complex, mitochondrial — human protein (gene DLAT, 647 amino acids, UniProt P10515). AlphaFold-predicted 3D structure; by default coloured by model confidence (blue = very high, orange = very low, typical of disordered regions).
Cytochrome P450 2C8 (CYP2C8) — Cytochrome P450 2C8 — human protein (gene CYP2C8, 490 amino acids, UniProt P10632). AlphaFold-predicted 3D structure; by default coloured by model confidence (blue = very high, orange = very low, typical of disordered regions).
Cytochrome P450 2D6 (CYP2D6) — Cytochrome P450 2D6 — human protein (gene CYP2D6, 497 amino acids, UniProt P10635). AlphaFold-predicted 3D structure; by default coloured by model confidence (blue = very high, orange = very low, typical of disordered regions).
Hepatic triacylglycerol lipase (LIPC) — Hepatic triacylglycerol lipase — human protein (gene LIPC, 499 amino acids, UniProt P11150). AlphaFold-predicted 3D structure; by default coloured by model confidence (blue = very high, orange = very low, typical of disordered regions).
Pyruvate dehydrogenase E1 component subunit beta, mitochondrial (PDHB) — Pyruvate dehydrogenase E1 component subunit beta, mitochondrial — human protein (gene PDHB, 359 amino acids, UniProt P11177). AlphaFold-predicted 3D structure; by default coloured by model confidence (blue = very high, orange = very low, typical of disordered regions).
Medium-chain specific acyl-CoA dehydrogenase, mitochondrial (ACADM) — Medium-chain specific acyl-CoA dehydrogenase, mitochondrial — human protein (gene ACADM, 421 amino acids, UniProt P11310). AlphaFold-predicted 3D structure; by default coloured by model confidence (blue = very high, orange = very low, typical of disordered regions).
Pyruvate carboxylase, mitochondrial (PC) — Pyruvate carboxylase, mitochondrial — human protein (gene PC, 1178 amino acids, UniProt P11498). AlphaFold-predicted 3D structure; by default coloured by model confidence (blue = very high, orange = very low, typical of disordered regions).
Cytochrome P450 2A6 (CYP2A6) — Cytochrome P450 2A6 — human protein (gene CYP2A6, 494 amino acids, UniProt P11509). AlphaFold-predicted 3D structure; by default coloured by model confidence (blue = very high, orange = very low, typical of disordered regions).
Aromatase (CYP19A1) — Aromatase — human protein (gene CYP19A1, 503 amino acids, UniProt P11511). AlphaFold-predicted 3D structure; by default coloured by model confidence (blue = very high, orange = very low, typical of disordered regions).
Cholesteryl ester transfer protein (CETP) — Cholesteryl ester transfer protein — human protein (gene CETP, 493 amino acids, UniProt P11597). AlphaFold-predicted 3D structure; by default coloured by model confidence (blue = very high, orange = very low, typical of disordered regions).
Cytochrome P450 2C9 (CYP2C9) — Cytochrome P450 2C9 — human protein (gene CYP2C9, 490 amino acids, UniProt P11712). AlphaFold-predicted 3D structure; by default coloured by model confidence (blue = very high, orange = very low, typical of disordered regions).
Alcohol dehydrogenase class-3 (ADH5) — Alcohol dehydrogenase class-3 — human protein (gene ADH5, 374 amino acids, UniProt P11766). AlphaFold-predicted 3D structure; by default coloured by model confidence (blue = very high, orange = very low, typical of disordered regions).
Electron transfer flavoprotein subunit alpha, mitochondrial (ETFA) — Electron transfer flavoprotein subunit alpha, mitochondrial — human protein (gene ETFA, 333 amino acids, UniProt P13804). AlphaFold-predicted 3D structure; by default coloured by model confidence (blue = very high, orange = very low, typical of disordered regions).
Beta-enolase (ENO3) — Beta-enolase — human protein (gene ENO3, 434 amino acids, UniProt P13929). AlphaFold-predicted 3D structure; by default coloured by model confidence (blue = very high, orange = very low, typical of disordered regions).
3 beta-hydroxysteroid dehydrogenase/Delta 5-->4-isomerase type 1 (HSD3B1) — 3 beta-hydroxysteroid dehydrogenase/Delta 5-->4-isomerase type 1 — human protein (gene HSD3B1, 373 amino acids, UniProt P14060). AlphaFold-predicted 3D structure; by default coloured by model confidence (blue = very high, orange = very low, typical of disordered regions).
17-beta-hydroxysteroid dehydrogenase type 1 (HSD17B1) — 17-beta-hydroxysteroid dehydrogenase type 1 — human protein (gene HSD17B1, 328 amino acids, UniProt P14061). AlphaFold-predicted 3D structure; by default coloured by model confidence (blue = very high, orange = very low, typical of disordered regions).
Farnesyl pyrophosphate synthase (FDPS) — Farnesyl pyrophosphate synthase — human protein (gene FDPS, 419 amino acids, UniProt P14324). AlphaFold-predicted 3D structure; by default coloured by model confidence (blue = very high, orange = very low, typical of disordered regions).
Aldo-keto reductase family 1 member A1 (AKR1A1) — Aldo-keto reductase family 1 member A1 — human protein (gene AKR1A1, 325 amino acids, UniProt P14550). AlphaFold-predicted 3D structure; by default coloured by model confidence (blue = very high, orange = very low, typical of disordered regions).
Phospholipase A2, membrane associated (PLA2G2A) — Phospholipase A2, membrane associated — human protein (gene PLA2G2A, 144 amino acids, UniProt P14555). AlphaFold-predicted 3D structure; by default coloured by model confidence (blue = very high, orange = very low, typical of disordered regions).
Aldo-keto reductase family 1 member B1 (AKR1B1) — Aldo-keto reductase family 1 member B1 — human protein (gene AKR1B1, 316 amino acids, UniProt P15121). AlphaFold-predicted 3D structure; by default coloured by model confidence (blue = very high, orange = very low, typical of disordered regions).
Phosphoglycerate mutase 2 (PGAM2) — Phosphoglycerate mutase 2 — human protein (gene PGAM2, 253 amino acids, UniProt P15259). AlphaFold-predicted 3D structure; by default coloured by model confidence (blue = very high, orange = very low, typical of disordered regions).
Arylsulfatase A (ARSA) — Arylsulfatase A — human protein (gene ARSA, 507 amino acids, UniProt P15289). AlphaFold-predicted 3D structure; by default coloured by model confidence (blue = very high, orange = very low, typical of disordered regions).
Beta-1,4-galactosyltransferase 1 (B4GALT1) — Beta-1,4-galactosyltransferase 1 — human protein (gene B4GALT1, 398 amino acids, UniProt P15291). AlphaFold-predicted 3D structure; by default coloured by model confidence (blue = very high, orange = very low, typical of disordered regions).
Prostatic acid phosphatase (ACP3) — Prostatic acid phosphatase — human protein (gene ACP3, 386 amino acids, UniProt P15309). AlphaFold-predicted 3D structure; by default coloured by model confidence (blue = very high, orange = very low, typical of disordered regions).
Cytochrome P450 11B1, mitochondrial (CYP11B1) — Cytochrome P450 11B1, mitochondrial — human protein (gene CYP11B1, 503 amino acids, UniProt P15538). AlphaFold-predicted 3D structure; by default coloured by model confidence (blue = very high, orange = very low, typical of disordered regions).
Polyunsaturated fatty acid lipoxygenase ALOX15 (ALOX15) — Polyunsaturated fatty acid lipoxygenase ALOX15 — human protein (gene ALOX15, 662 amino acids, UniProt P16050). AlphaFold-predicted 3D structure; by default coloured by model confidence (blue = very high, orange = very low, typical of disordered regions).
Carbonyl reductase [NADPH] 1 (CBR1) — Carbonyl reductase [NADPH] 1 — human protein (gene CBR1, 277 amino acids, UniProt P16152). AlphaFold-predicted 3D structure; by default coloured by model confidence (blue = very high, orange = very low, typical of disordered regions).
Short-chain specific acyl-CoA dehydrogenase, mitochondrial (ACADS) — Short-chain specific acyl-CoA dehydrogenase, mitochondrial — human protein (gene ACADS, 412 amino acids, UniProt P16219). AlphaFold-predicted 3D structure; by default coloured by model confidence (blue = very high, orange = very low, typical of disordered regions).
Pancreatic triacylglycerol lipase (PNLIP) — Pancreatic triacylglycerol lipase — human protein (gene PNLIP, 465 amino acids, UniProt P16233). AlphaFold-predicted 3D structure; by default coloured by model confidence (blue = very high, orange = very low, typical of disordered regions).
UDP-glucuronosyltransferase 2B7 (UGT2B7) — UDP-glucuronosyltransferase 2B7 — human protein (gene UGT2B7, 529 amino acids, UniProt P16662). AlphaFold-predicted 3D structure; by default coloured by model confidence (blue = very high, orange = very low, typical of disordered regions).
1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase gamma-2 (PLCG2) — 1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase gamma-2 — human protein (gene PLCG2, 1265 amino acids, UniProt P16885). AlphaFold-predicted 3D structure; by default coloured by model confidence (blue = very high, orange = very low, typical of disordered regions).
Fumarylacetoacetase (FAH) — Fumarylacetoacetase — human protein (gene FAH, 419 amino acids, UniProt P16930). AlphaFold-predicted 3D structure; by default coloured by model confidence (blue = very high, orange = very low, typical of disordered regions).
Alpha-N-acetylgalactosaminidase (NAGA) — Alpha-N-acetylgalactosaminidase — human protein (gene NAGA, 411 amino acids, UniProt P17050). AlphaFold-predicted 3D structure; by default coloured by model confidence (blue = very high, orange = very low, typical of disordered regions).
Aspartate aminotransferase, cytoplasmic (GOT1) — Aspartate aminotransferase, cytoplasmic — human protein (gene GOT1, 413 amino acids, UniProt P17174). AlphaFold-predicted 3D structure; by default coloured by model confidence (blue = very high, orange = very low, typical of disordered regions).
Sphingomyelin phosphodiesterase (SMPD1) — Sphingomyelin phosphodiesterase — human protein (gene SMPD1, 631 amino acids, UniProt P17405). AlphaFold-predicted 3D structure; by default coloured by model confidence (blue = very high, orange = very low, typical of disordered regions).
Aldo-keto reductase family 1 member C4 (AKR1C4) — Aldo-keto reductase family 1 member C4 — human protein (gene AKR1C4, 323 amino acids, UniProt P17516). AlphaFold-predicted 3D structure; by default coloured by model confidence (blue = very high, orange = very low, typical of disordered regions).
Ganglioside GM2 activator (GM2A) — Ganglioside GM2 activator — human protein (gene GM2A, 193 amino acids, UniProt P17900). AlphaFold-predicted 3D structure; by default coloured by model confidence (blue = very high, orange = very low, typical of disordered regions).
Polyunsaturated fatty acid lipoxygenase ALOX12 (ALOX12) — Polyunsaturated fatty acid lipoxygenase ALOX12 — human protein (gene ALOX12, 663 amino acids, UniProt P18054). AlphaFold-predicted 3D structure; by default coloured by model confidence (blue = very high, orange = very low, typical of disordered regions).
3-oxo-5-alpha-steroid 4-dehydrogenase 1 (SRD5A1) — 3-oxo-5-alpha-steroid 4-dehydrogenase 1 — human protein (gene SRD5A1, 259 amino acids, UniProt P18405). AlphaFold-predicted 3D structure; by default coloured by model confidence (blue = very high, orange = very low, typical of disordered regions).
Phosphoglycerate mutase 1 (PGAM1) — Phosphoglycerate mutase 1 — human protein (gene PGAM1, 254 amino acids, UniProt P18669). AlphaFold-predicted 3D structure; by default coloured by model confidence (blue = very high, orange = very low, typical of disordered regions).
Peptidyl-glycine alpha-amidating monooxygenase (PAM) — Peptidyl-glycine alpha-amidating monooxygenase — human protein (gene PAM, 973 amino acids, UniProt P19021). AlphaFold-predicted 3D structure; by default coloured by model confidence (blue = very high, orange = very low, typical of disordered regions).
Cytochrome P450 11B2, mitochondrial (CYP11B2) — Cytochrome P450 11B2, mitochondrial — human protein (gene CYP11B2, 503 amino acids, UniProt P19099). AlphaFold-predicted 3D structure; by default coloured by model confidence (blue = very high, orange = very low, typical of disordered regions).
1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase gamma-1 (PLCG1) — 1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase gamma-1 — human protein (gene PLCG1, 1290 amino acids, UniProt P19174). AlphaFold-predicted 3D structure; by default coloured by model confidence (blue = very high, orange = very low, typical of disordered regions).
Galactoside alpha-(1,2)-fucosyltransferase 1 (FUT1) — Galactoside alpha-(1,2)-fucosyltransferase 1 — human protein (gene FUT1, 365 amino acids, UniProt P19526). AlphaFold-predicted 3D structure; by default coloured by model confidence (blue = very high, orange = very low, typical of disordered regions).
Bile salt-activated lipase (CEL) — Bile salt-activated lipase — human protein (gene CEL, 753 amino acids, UniProt P19835). AlphaFold-predicted 3D structure; by default coloured by model confidence (blue = very high, orange = very low, typical of disordered regions).
L-serine dehydratase/L-threonine deaminase (SDS) — L-serine dehydratase/L-threonine deaminase — human protein (gene SDS, 328 amino acids, UniProt P20132). AlphaFold-predicted 3D structure; by default coloured by model confidence (blue = very high, orange = very low, typical of disordered regions).
Cytochrome P450 2B6 (CYP2B6) — Cytochrome P450 2B6 — human protein (gene CYP2B6, 491 amino acids, UniProt P20813). AlphaFold-predicted 3D structure; by default coloured by model confidence (blue = very high, orange = very low, typical of disordered regions).
Cytochrome P450 3A5 (CYP3A5) — Cytochrome P450 3A5 — human protein (gene CYP3A5, 502 amino acids, UniProt P20815). AlphaFold-predicted 3D structure; by default coloured by model confidence (blue = very high, orange = very low, typical of disordered regions).
3-galactosyl-N-acetylglucosaminide 4-alpha-L-fucosyltransferase FUT3 (FUT3) — 3-galactosyl-N-acetylglucosaminide 4-alpha-L-fucosyltransferase FUT3 — human protein (gene FUT3, 361 amino acids, UniProt P21217). AlphaFold-predicted 3D structure; by default coloured by model confidence (blue = very high, orange = very low, typical of disordered regions).
Cytoplasmic aconitate hydratase (ACO1) — Cytoplasmic aconitate hydratase — human protein (gene ACO1, 889 amino acids, UniProt P21399). AlphaFold-predicted 3D structure; by default coloured by model confidence (blue = very high, orange = very low, typical of disordered regions).
Succinate dehydrogenase [ubiquinone] iron-sulfur subunit, mitochondrial (SDHB) — Succinate dehydrogenase [ubiquinone] iron-sulfur subunit, mitochondrial — human protein (gene SDHB, 280 amino acids, UniProt P21912). AlphaFold-predicted 3D structure; by default coloured by model confidence (blue = very high, orange = very low, typical of disordered regions).
2-oxoisovalerate dehydrogenase subunit beta, mitochondrial (BCKDHB) — 2-oxoisovalerate dehydrogenase subunit beta, mitochondrial — human protein (gene BCKDHB, 392 amino acids, UniProt P21953). AlphaFold-predicted 3D structure; by default coloured by model confidence (blue = very high, orange = very low, typical of disordered regions).
Catechol O-methyltransferase (COMT) — Catechol O-methyltransferase — human protein (gene COMT, 271 amino acids, UniProt P21964). AlphaFold-predicted 3D structure; by default coloured by model confidence (blue = very high, orange = very low, typical of disordered regions).
Sterol carrier protein 2 (SCP2) — Sterol carrier protein 2 — human protein (gene SCP2, 547 amino acids, UniProt P22307). AlphaFold-predicted 3D structure; by default coloured by model confidence (blue = very high, orange = very low, typical of disordered regions).
UDP-glucuronosyltransferase 1A1 (UGT1A1) — UDP-glucuronosyltransferase 1A1 — human protein (gene UGT1A1, 533 amino acids, UniProt P22309). AlphaFold-predicted 3D structure; by default coloured by model confidence (blue = very high, orange = very low, typical of disordered regions).
UDP-glucuronosyltransferase 1A4 (UGT1A4) — UDP-glucuronosyltransferase 1A4 — human protein (gene UGT1A4, 534 amino acids, UniProt P22310). AlphaFold-predicted 3D structure; by default coloured by model confidence (blue = very high, orange = very low, typical of disordered regions).
NADPH:adrenodoxin oxidoreductase, mitochondrial (FDXR) — NADPH:adrenodoxin oxidoreductase, mitochondrial — human protein (gene FDXR, 491 amino acids, UniProt P22570). AlphaFold-predicted 3D structure; by default coloured by model confidence (blue = very high, orange = very low, typical of disordered regions).
Cytochrome P450 7A1 (CYP7A1) — Cytochrome P450 7A1 — human protein (gene CYP7A1, 504 amino acids, UniProt P22680). AlphaFold-predicted 3D structure; by default coloured by model confidence (blue = very high, orange = very low, typical of disordered regions).
Deacylase AADAC (AADAC) — Deacylase AADAC — human protein (gene AADAC, 399 amino acids, UniProt P22760). AlphaFold-predicted 3D structure; by default coloured by model confidence (blue = very high, orange = very low, typical of disordered regions).
Liver carboxylesterase 1 (CES1) — Liver carboxylesterase 1 — human protein (gene CES1, 567 amino acids, UniProt P23141). AlphaFold-predicted 3D structure; by default coloured by model confidence (blue = very high, orange = very low, typical of disordered regions).
Prostaglandin G/H synthase 1 (PTGS1) — Prostaglandin G/H synthase 1 — human protein (gene PTGS1, 599 amino acids, UniProt P23219). AlphaFold-predicted 3D structure; by default coloured by model confidence (blue = very high, orange = very low, typical of disordered regions).
Carnitine O-palmitoyltransferase 2, mitochondrial (CPT2) — Carnitine O-palmitoyltransferase 2, mitochondrial — human protein (gene CPT2, 658 amino acids, UniProt P23786). AlphaFold-predicted 3D structure; by default coloured by model confidence (blue = very high, orange = very low, typical of disordered regions).
Cytochrome P450 3A7 (CYP3A7) — Cytochrome P450 3A7 — human protein (gene CYP3A7, 503 amino acids, UniProt P24462). AlphaFold-predicted 3D structure; by default coloured by model confidence (blue = very high, orange = very low, typical of disordered regions).
Thromboxane-A synthase (TBXAS1) — Thromboxane-A synthase — human protein (gene TBXAS1, 533 amino acids, UniProt P24557). AlphaFold-predicted 3D structure; by default coloured by model confidence (blue = very high, orange = very low, typical of disordered regions).
Acetyl-CoA acetyltransferase, mitochondrial (ACAT1) — Acetyl-CoA acetyltransferase, mitochondrial — human protein (gene ACAT1, 427 amino acids, UniProt P24752). AlphaFold-predicted 3D structure; by default coloured by model confidence (blue = very high, orange = very low, typical of disordered regions).
3 beta-hydroxysteroid dehydrogenase/Delta 5-->4-isomerase type 2 (HSD3B2) — 3 beta-hydroxysteroid dehydrogenase/Delta 5-->4-isomerase type 2 — human protein (gene HSD3B2, 372 amino acids, UniProt P26439). AlphaFold-predicted 3D structure; by default coloured by model confidence (blue = very high, orange = very low, typical of disordered regions).
Isovaleryl-CoA dehydrogenase, mitochondrial (IVD) — Isovaleryl-CoA dehydrogenase, mitochondrial — human protein (gene IVD, 426 amino acids, UniProt P26440). AlphaFold-predicted 3D structure; by default coloured by model confidence (blue = very high, orange = very low, typical of disordered regions).
Ceramide synthase 1 (CERS1) — Ceramide synthase 1 — human protein (gene CERS1, 350 amino acids, UniProt P27544). AlphaFold-predicted 3D structure; by default coloured by model confidence (blue = very high, orange = very low, typical of disordered regions).
Acyloxyacyl hydrolase (AOAH) — Acyloxyacyl hydrolase — human protein (gene AOAH, 575 amino acids, UniProt P28039). AlphaFold-predicted 3D structure; by default coloured by model confidence (blue = very high, orange = very low, typical of disordered regions).
Glutathione S-transferase Mu 2 (GSTM2) — Glutathione S-transferase Mu 2 — human protein (gene GSTM2, 218 amino acids, UniProt P28161). AlphaFold-predicted 3D structure; by default coloured by model confidence (blue = very high, orange = very low, typical of disordered regions).
Long-chain specific acyl-CoA dehydrogenase, mitochondrial (ACADL) — Long-chain specific acyl-CoA dehydrogenase, mitochondrial — human protein (gene ACADL, 430 amino acids, UniProt P28330). AlphaFold-predicted 3D structure; by default coloured by model confidence (blue = very high, orange = very low, typical of disordered regions).
11-beta-hydroxysteroid dehydrogenase 1 (HSD11B1) — 11-beta-hydroxysteroid dehydrogenase 1 — human protein (gene HSD11B1, 292 amino acids, UniProt P28845). AlphaFold-predicted 3D structure; by default coloured by model confidence (blue = very high, orange = very low, typical of disordered regions).
Pyruvate dehydrogenase E1 component subunit alpha, testis-specific form, mitochondrial (PDHA2) — Pyruvate dehydrogenase E1 component subunit alpha, testis-specific form, mitochondrial — human protein (gene PDHA2, 388 amino acids, UniProt P29803). AlphaFold-predicted 3D structure; by default coloured by model confidence (blue = very high, orange = very low, typical of disordered regions).
Peroxiredoxin-6 (PRDX6) — Peroxiredoxin-6 — human protein (gene PRDX6, 224 amino acids, UniProt P30041). AlphaFold-predicted 3D structure; by default coloured by model confidence (blue = very high, orange = very low, typical of disordered regions).
Enoyl-CoA hydratase, mitochondrial (ECHS1) — Enoyl-CoA hydratase, mitochondrial — human protein (gene ECHS1, 290 amino acids, UniProt P30084). AlphaFold-predicted 3D structure; by default coloured by model confidence (blue = very high, orange = very low, typical of disordered regions).
Aldehyde dehydrogenase, dimeric NADP-preferring (ALDH3A1) — Aldehyde dehydrogenase, dimeric NADP-preferring — human protein (gene ALDH3A1, 453 amino acids, UniProt P30838). AlphaFold-predicted 3D structure; by default coloured by model confidence (blue = very high, orange = very low, typical of disordered regions).
3-oxo-5-alpha-steroid 4-dehydrogenase 2 (SRD5A2) — 3-oxo-5-alpha-steroid 4-dehydrogenase 2 — human protein (gene SRD5A2, 254 amino acids, UniProt P31213). AlphaFold-predicted 3D structure; by default coloured by model confidence (blue = very high, orange = very low, typical of disordered regions).
Type II inositol 1,4,5-trisphosphate 5-phosphatase (INPP5B) — Type II inositol 1,4,5-trisphosphate 5-phosphatase — human protein (gene INPP5B, 993 amino acids, UniProt P32019). AlphaFold-predicted 3D structure; by default coloured by model confidence (blue = very high, orange = very low, typical of disordered regions).
Pyrroline-5-carboxylate reductase 1, mitochondrial (PYCR1) — Pyrroline-5-carboxylate reductase 1, mitochondrial — human protein (gene PYCR1, 319 amino acids, UniProt P32322). AlphaFold-predicted 3D structure; by default coloured by model confidence (blue = very high, orange = very low, typical of disordered regions).
Cystathionine gamma-lyase (CTH) — Cystathionine gamma-lyase — human protein (gene CTH, 405 amino acids, UniProt P32929). AlphaFold-predicted 3D structure; by default coloured by model confidence (blue = very high, orange = very low, typical of disordered regions).
Long-chain-fatty-acid--CoA ligase 1 (ACSL1) — Long-chain-fatty-acid--CoA ligase 1 — human protein (gene ACSL1, 698 amino acids, UniProt P33121). AlphaFold-predicted 3D structure; by default coloured by model confidence (blue = very high, orange = very low, typical of disordered regions).
Cytochrome P450 2C18 (CYP2C18) — Cytochrome P450 2C18 — human protein (gene CYP2C18, 490 amino acids, UniProt P33260). AlphaFold-predicted 3D structure; by default coloured by model confidence (blue = very high, orange = very low, typical of disordered regions).
Cytochrome P450 2C19 (CYP2C19) — Cytochrome P450 2C19 — human protein (gene CYP2C19, 490 amino acids, UniProt P33261). AlphaFold-predicted 3D structure; by default coloured by model confidence (blue = very high, orange = very low, typical of disordered regions).
Bifunctional epoxide hydrolase 2 [Includes: Cytosolic epoxide hydrolase 2 (EPHX2) — Bifunctional epoxide hydrolase 2 [Includes: Cytosolic epoxide hydrolase 2 — human protein (gene EPHX2, 555 amino acids, UniProt P34913). AlphaFold-predicted 3D structure; by default coloured by model confidence (blue = very high, orange = very low, typical of disordered regions).
Prostaglandin G/H synthase 2 (PTGS2) — Prostaglandin G/H synthase 2 — human protein (gene PTGS2, 604 amino acids, UniProt P35354). AlphaFold-predicted 3D structure; by default coloured by model confidence (blue = very high, orange = very low, typical of disordered regions).
UDP-glucuronosyltransferase 1A3 (UGT1A3) — UDP-glucuronosyltransferase 1A3 — human protein (gene UGT1A3, 534 amino acids, UniProt P35503). AlphaFold-predicted 3D structure; by default coloured by model confidence (blue = very high, orange = very low, typical of disordered regions).
Cystathionine beta-synthase (CBS) — Cystathionine beta-synthase — human protein (gene CBS, 551 amino acids, UniProt P35520). AlphaFold-predicted 3D structure; by default coloured by model confidence (blue = very high, orange = very low, typical of disordered regions).
Sterol O-acyltransferase 1 (SOAT1) — Sterol O-acyltransferase 1 — human protein (gene SOAT1, 550 amino acids, UniProt P35610). AlphaFold-predicted 3D structure; by default coloured by model confidence (blue = very high, orange = very low, typical of disordered regions).
Hydroxymethylglutaryl-CoA lyase, mitochondrial (HMGCL) — Hydroxymethylglutaryl-CoA lyase, mitochondrial — human protein (gene HMGCL, 325 amino acids, UniProt P35914). AlphaFold-predicted 3D structure; by default coloured by model confidence (blue = very high, orange = very low, typical of disordered regions).
Sterol regulatory element-binding protein 1 (SREBF1) — Sterol regulatory element-binding protein 1 — human protein (gene SREBF1, 1147 amino acids, UniProt P36956). AlphaFold-predicted 3D structure; by default coloured by model confidence (blue = very high, orange = very low, typical of disordered regions).
Dihydrolipoyllysine-residue succinyltransferase component of 2-oxoglutarate dehydrogenase complex, mitochondrial (DLST) — Dihydrolipoyllysine-residue succinyltransferase component of 2-oxoglutarate dehydrogenase complex, mitochondrial — human protein (gene DLST, 453 amino acids, UniProt P36957). AlphaFold-predicted 3D structure; by default coloured by model confidence (blue = very high, orange = very low, typical of disordered regions).
Phospholipid hydroperoxide glutathione peroxidase GPX4 (GPX4) — Phospholipid hydroperoxide glutathione peroxidase GPX4 — human protein (gene GPX4, 197 amino acids, UniProt P36969). AlphaFold-predicted 3D structure; by default coloured by model confidence (blue = very high, orange = very low, typical of disordered regions).
17-beta-hydroxysteroid dehydrogenase type 3 (HSD17B3) — 17-beta-hydroxysteroid dehydrogenase type 3 — human protein (gene HSD17B3, 310 amino acids, UniProt P37058). AlphaFold-predicted 3D structure; by default coloured by model confidence (blue = very high, orange = very low, typical of disordered regions).
17-beta-hydroxysteroid dehydrogenase type 2 (HSD17B2) — 17-beta-hydroxysteroid dehydrogenase type 2 — human protein (gene HSD17B2, 387 amino acids, UniProt P37059). AlphaFold-predicted 3D structure; by default coloured by model confidence (blue = very high, orange = very low, typical of disordered regions).
Squalene synthase (FDFT1) — Squalene synthase — human protein (gene FDFT1, 417 amino acids, UniProt P37268). AlphaFold-predicted 3D structure; by default coloured by model confidence (blue = very high, orange = very low, typical of disordered regions).
Phosphatidylinositol N-acetylglucosaminyltransferase subunit A (PIGA) — Phosphatidylinositol N-acetylglucosaminyltransferase subunit A — human protein (gene PIGA, 484 amino acids, UniProt P37287). AlphaFold-predicted 3D structure; by default coloured by model confidence (blue = very high, orange = very low, typical of disordered regions).
Electron transfer flavoprotein subunit beta (ETFB) — Electron transfer flavoprotein subunit beta — human protein (gene ETFB, 255 amino acids, UniProt P38117). AlphaFold-predicted 3D structure; by default coloured by model confidence (blue = very high, orange = very low, typical of disordered regions).
Lysosomal acid lipase/cholesteryl ester hydrolase (LIPA) — Lysosomal acid lipase/cholesteryl ester hydrolase — human protein (gene LIPA, 399 amino acids, UniProt P38571). AlphaFold-predicted 3D structure; by default coloured by model confidence (blue = very high, orange = very low, typical of disordered regions).
Phospholipase A2 group V (PLA2G5) — Phospholipase A2 group V — human protein (gene PLA2G5, 138 amino acids, UniProt P39877). AlphaFold-predicted 3D structure; by default coloured by model confidence (blue = very high, orange = very low, typical of disordered regions).
All-trans-retinol dehydrogenase [NAD(+)] ADH7 (ADH7) — All-trans-retinol dehydrogenase [NAD(+)] ADH7 — human protein (gene ADH7, 386 amino acids, UniProt P40394). AlphaFold-predicted 3D structure; by default coloured by model confidence (blue = very high, orange = very low, typical of disordered regions).
Malate dehydrogenase, cytoplasmic (MDH1) — Malate dehydrogenase, cytoplasmic — human protein (gene MDH1, 334 amino acids, UniProt P40925). AlphaFold-predicted 3D structure; by default coloured by model confidence (blue = very high, orange = very low, typical of disordered regions).
Malate dehydrogenase, mitochondrial (MDH2) — Malate dehydrogenase, mitochondrial — human protein (gene MDH2, 338 amino acids, UniProt P40926). AlphaFold-predicted 3D structure; by default coloured by model confidence (blue = very high, orange = very low, typical of disordered regions).
Trifunctional enzyme subunit alpha, mitochondrial (HADHA) — Trifunctional enzyme subunit alpha, mitochondrial — human protein (gene HADHA, 763 amino acids, UniProt P40939). AlphaFold-predicted 3D structure; by default coloured by model confidence (blue = very high, orange = very low, typical of disordered regions).
Prostaglandin-H2 D-isomerase (PTGDS) — Prostaglandin-H2 D-isomerase — human protein (gene PTGDS, 190 amino acids, UniProt P41222). AlphaFold-predicted 3D structure; by default coloured by model confidence (blue = very high, orange = very low, typical of disordered regions).
Patatin-like phospholipase domain-containing protein 4 (PNPLA4) — Patatin-like phospholipase domain-containing protein 4 — human protein (gene PNPLA4, 253 amino acids, UniProt P41247). AlphaFold-predicted 3D structure; by default coloured by model confidence (blue = very high, orange = very low, typical of disordered regions).
Enoyl-CoA delta isomerase 1, mitochondrial (ECI1) — Enoyl-CoA delta isomerase 1, mitochondrial — human protein (gene ECI1, 302 amino acids, UniProt P42126). AlphaFold-predicted 3D structure; by default coloured by model confidence (blue = very high, orange = very low, typical of disordered regions).
Aldo-keto reductase family 1 member C3 (AKR1C3) — Aldo-keto reductase family 1 member C3 — human protein (gene AKR1C3, 323 amino acids, UniProt P42330). AlphaFold-predicted 3D structure; by default coloured by model confidence (blue = very high, orange = very low, typical of disordered regions).
3-ketoacyl-CoA thiolase, mitochondrial (ACAA2) — 3-ketoacyl-CoA thiolase, mitochondrial — human protein (gene ACAA2, 397 amino acids, UniProt P42765). AlphaFold-predicted 3D structure; by default coloured by model confidence (blue = very high, orange = very low, typical of disordered regions).
Platelet-activating factor acetylhydrolase IB subunit beta (PAFAH1B1) — Platelet-activating factor acetylhydrolase IB subunit beta — human protein (gene PAFAH1B1, 410 amino acids, UniProt P43034). AlphaFold-predicted 3D structure; by default coloured by model confidence (blue = very high, orange = very low, typical of disordered regions).
Carnitine O-acetyltransferase (CRAT) — Carnitine O-acetyltransferase — human protein (gene CRAT, 626 amino acids, UniProt P43155). AlphaFold-predicted 3D structure; by default coloured by model confidence (blue = very high, orange = very low, typical of disordered regions).
Aldehyde dehydrogenase family 3 member B1 (ALDH3B1) — Aldehyde dehydrogenase family 3 member B1 — human protein (gene ALDH3B1, 468 amino acids, UniProt P43353). AlphaFold-predicted 3D structure; by default coloured by model confidence (blue = very high, orange = very low, typical of disordered regions).
Short/branched chain specific acyl-CoA dehydrogenase, mitochondrial (ACADSB) — Short/branched chain specific acyl-CoA dehydrogenase, mitochondrial — human protein (gene ACADSB, 432 amino acids, UniProt P45954). AlphaFold-predicted 3D structure; by default coloured by model confidence (blue = very high, orange = very low, typical of disordered regions).
Acetylserotonin O-methyltransferase (ASMT) — Acetylserotonin O-methyltransferase — human protein (gene ASMT, 345 amino acids, UniProt P46597). AlphaFold-predicted 3D structure; by default coloured by model confidence (blue = very high, orange = very low, typical of disordered regions).
Cytosolic phospholipase A2 (PLA2G4A) — Cytosolic phospholipase A2 — human protein (gene PLA2G4A, 749 amino acids, UniProt P47712). AlphaFold-predicted 3D structure; by default coloured by model confidence (blue = very high, orange = very low, typical of disordered regions).
Retinaldehyde dehydrogenase 3 (ALDH1A3) — Retinaldehyde dehydrogenase 3 — human protein (gene ALDH1A3, 512 amino acids, UniProt P47895). AlphaFold-predicted 3D structure; by default coloured by model confidence (blue = very high, orange = very low, typical of disordered regions).
Aldehyde dehydrogenase family 3 member B2 (ALDH3B2) — Aldehyde dehydrogenase family 3 member B2 — human protein (gene ALDH3B2, 385 amino acids, UniProt P48448). AlphaFold-predicted 3D structure; by default coloured by model confidence (blue = very high, orange = very low, typical of disordered regions).
Lanosterol synthase (LSS) — Lanosterol synthase — human protein (gene LSS, 732 amino acids, UniProt P48449). AlphaFold-predicted 3D structure; by default coloured by model confidence (blue = very high, orange = very low, typical of disordered regions).
Phosphatidylserine synthase 1 (PTDSS1) — Phosphatidylserine synthase 1 — human protein (gene PTDSS1, 473 amino acids, UniProt P48651). AlphaFold-predicted 3D structure; by default coloured by model confidence (blue = very high, orange = very low, typical of disordered regions).
Isocitrate dehydrogenase [NADP], mitochondrial (IDH2) — Isocitrate dehydrogenase [NADP], mitochondrial — human protein (gene IDH2, 452 amino acids, UniProt P48735). AlphaFold-predicted 3D structure; by default coloured by model confidence (blue = very high, orange = very low, typical of disordered regions).
Flavin-containing monooxygenase 5 (FMO5) — Flavin-containing monooxygenase 5 — human protein (gene FMO5, 533 amino acids, UniProt P49326). AlphaFold-predicted 3D structure; by default coloured by model confidence (blue = very high, orange = very low, typical of disordered regions).
Fatty acid synthase (FASN) — Fatty acid synthase — human protein (gene FASN, 2511 amino acids, UniProt P49327). AlphaFold-predicted 3D structure; by default coloured by model confidence (blue = very high, orange = very low, typical of disordered regions).
Protein farnesyltransferase subunit beta (FNTB) — Protein farnesyltransferase subunit beta — human protein (gene FNTB, 437 amino acids, UniProt P49356). AlphaFold-predicted 3D structure; by default coloured by model confidence (blue = very high, orange = very low, typical of disordered regions).
Choline-phosphate cytidylyltransferase A (PCYT1A) — Choline-phosphate cytidylyltransferase A — human protein (gene PCYT1A, 367 amino acids, UniProt P49585). AlphaFold-predicted 3D structure; by default coloured by model confidence (blue = very high, orange = very low, typical of disordered regions).
Very long-chain acyl-CoA dehydrogenase, mitochondrial (ACADVL) — Very long-chain acyl-CoA dehydrogenase, mitochondrial — human protein (gene ACADVL, 655 amino acids, UniProt P49748). AlphaFold-predicted 3D structure; by default coloured by model confidence (blue = very high, orange = very low, typical of disordered regions).
Acyl-coenzyme A thioesterase 2, mitochondrial (ACOT2) — Acyl-coenzyme A thioesterase 2, mitochondrial — human protein (gene ACOT2, 483 amino acids, UniProt P49753). AlphaFold-predicted 3D structure; by default coloured by model confidence (blue = very high, orange = very low, typical of disordered regions).
Sulfotransferase 1E1 (SULT1E1) — Sulfotransferase 1E1 — human protein (gene SULT1E1, 294 amino acids, UniProt P49888). AlphaFold-predicted 3D structure; by default coloured by model confidence (blue = very high, orange = very low, typical of disordered regions).
Isocitrate dehydrogenase [NAD] subunit alpha, mitochondrial (IDH3A) — Isocitrate dehydrogenase [NAD] subunit alpha, mitochondrial — human protein (gene IDH3A, 366 amino acids, UniProt P50213). AlphaFold-predicted 3D structure; by default coloured by model confidence (blue = very high, orange = very low, typical of disordered regions).
Sulfotransferase 1A1 (SULT1A1) — Sulfotransferase 1A1 — human protein (gene SULT1A1, 295 amino acids, UniProt P50225). AlphaFold-predicted 3D structure; by default coloured by model confidence (blue = very high, orange = very low, typical of disordered regions).
Sulfotransferase 1A2 (SULT1A2) — Sulfotransferase 1A2 — human protein (gene SULT1A2, 295 amino acids, UniProt P50226). AlphaFold-predicted 3D structure; by default coloured by model confidence (blue = very high, orange = very low, typical of disordered regions).
Ras-related protein Rab-7a (RAB7A) — Ras-related protein Rab-7a — human protein (gene RAB7A, 207 amino acids, UniProt P51149). AlphaFold-predicted 3D structure; by default coloured by model confidence (blue = very high, orange = very low, typical of disordered regions).
1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase delta-1 (PLCD1) — 1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase delta-1 — human protein (gene PLCD1, 756 amino acids, UniProt P51178). AlphaFold-predicted 3D structure; by default coloured by model confidence (blue = very high, orange = very low, typical of disordered regions).
Isocitrate dehydrogenase [NAD] subunit gamma, mitochondrial (IDH3G) — Isocitrate dehydrogenase [NAD] subunit gamma, mitochondrial — human protein (gene IDH3G, 393 amino acids, UniProt P51553). AlphaFold-predicted 3D structure; by default coloured by model confidence (blue = very high, orange = very low, typical of disordered regions).
Cytochrome P450 2J2 (CYP2J2) — Cytochrome P450 2J2 — human protein (gene CYP2J2, 502 amino acids, UniProt P51589). AlphaFold-predicted 3D structure; by default coloured by model confidence (blue = very high, orange = very low, typical of disordered regions).
Aldehyde dehydrogenase family 3 member A2 (ALDH3A2) — Aldehyde dehydrogenase family 3 member A2 — human protein (gene ALDH3A2, 485 amino acids, UniProt P51648). AlphaFold-predicted 3D structure; by default coloured by model confidence (blue = very high, orange = very low, typical of disordered regions).
Peroxisomal multifunctional enzyme type 2 (HSD17B4) — Peroxisomal multifunctional enzyme type 2 — human protein (gene HSD17B4, 736 amino acids, UniProt P51659). AlphaFold-predicted 3D structure; by default coloured by model confidence (blue = very high, orange = very low, typical of disordered regions).
Aldo-keto reductase family 1 member D1 (AKR1D1) — Aldo-keto reductase family 1 member D1 — human protein (gene AKR1D1, 326 amino acids, UniProt P51857). AlphaFold-predicted 3D structure; by default coloured by model confidence (blue = very high, orange = very low, typical of disordered regions).
4-galactosyl-N-acetylglucosaminide 3-alpha-L-fucosyltransferase FUT6 (FUT6) — 4-galactosyl-N-acetylglucosaminide 3-alpha-L-fucosyltransferase FUT6 — human protein (gene FUT6, 359 amino acids, UniProt P51993). AlphaFold-predicted 3D structure; by default coloured by model confidence (blue = very high, orange = very low, typical of disordered regions).
2-iminobutanoate/2-iminopropanoate deaminase (RIDA) — 2-iminobutanoate/2-iminopropanoate deaminase — human protein (gene RIDA, 137 amino acids, UniProt P52758). AlphaFold-predicted 3D structure; by default coloured by model confidence (blue = very high, orange = very low, typical of disordered regions).
Aldo-keto reductase family 1 member C2 (AKR1C2) — Aldo-keto reductase family 1 member C2 — human protein (gene AKR1C2, 323 amino acids, UniProt P52895). AlphaFold-predicted 3D structure; by default coloured by model confidence (blue = very high, orange = very low, typical of disordered regions).
ATP-citrate synthase (ACLY) — ATP-citrate synthase — human protein (gene ACLY, 1101 amino acids, UniProt P53396). AlphaFold-predicted 3D structure; by default coloured by model confidence (blue = very high, orange = very low, typical of disordered regions).
Succinate--CoA ligase [ADP/GDP-forming] subunit alpha, mitochondrial (SUCLG1) — Succinate--CoA ligase [ADP/GDP-forming] subunit alpha, mitochondrial — human protein (gene SUCLG1, 346 amino acids, UniProt P53597). AlphaFold-predicted 3D structure; by default coloured by model confidence (blue = very high, orange = very low, typical of disordered regions).
Diphosphomevalonate decarboxylase (MVD) — Diphosphomevalonate decarboxylase — human protein (gene MVD, 400 amino acids, UniProt P53602). AlphaFold-predicted 3D structure; by default coloured by model confidence (blue = very high, orange = very low, typical of disordered regions).
Phospholipase A and acyltransferase 3 (PLAAT3) — Phospholipase A and acyltransferase 3 — human protein (gene PLAAT3, 162 amino acids, UniProt P53816). AlphaFold-predicted 3D structure; by default coloured by model confidence (blue = very high, orange = very low, typical of disordered regions).
Pancreatic lipase-related protein 2 (PNLIPRP2) — Pancreatic lipase-related protein 2 — human protein (gene PNLIPRP2, 469 amino acids, UniProt P54317). AlphaFold-predicted 3D structure; by default coloured by model confidence (blue = very high, orange = very low, typical of disordered regions).
5'-AMP-activated protein kinase subunit gamma-1 (PRKAG1) — 5'-AMP-activated protein kinase subunit gamma-1 — human protein (gene PRKAG1, 331 amino acids, UniProt P54619). AlphaFold-predicted 3D structure; by default coloured by model confidence (blue = very high, orange = very low, typical of disordered regions).
Branched-chain-amino-acid aminotransferase, cytosolic (BCAT1) — Branched-chain-amino-acid aminotransferase, cytosolic — human protein (gene BCAT1, 386 amino acids, UniProt P54687). AlphaFold-predicted 3D structure; by default coloured by model confidence (blue = very high, orange = very low, typical of disordered regions).
Galactocerebrosidase (GALC) — Galactocerebrosidase — human protein (gene GALC, 685 amino acids, UniProt P54803). AlphaFold-predicted 3D structure; by default coloured by model confidence (blue = very high, orange = very low, typical of disordered regions).
UDP-glucuronosyltransferase 2B15 (UGT2B15) — UDP-glucuronosyltransferase 2B15 — human protein (gene UGT2B15, 530 amino acids, UniProt P54855). AlphaFold-predicted 3D structure; by default coloured by model confidence (blue = very high, orange = very low, typical of disordered regions).
Hydroxymethylglutaryl-CoA synthase, mitochondrial (HMGCS2) — Hydroxymethylglutaryl-CoA synthase, mitochondrial — human protein (gene HMGCS2, 508 amino acids, UniProt P54868). AlphaFold-predicted 3D structure; by default coloured by model confidence (blue = very high, orange = very low, typical of disordered regions).
Trifunctional enzyme subunit beta, mitochondrial (HADHB) — Trifunctional enzyme subunit beta, mitochondrial — human protein (gene HADHB, 474 amino acids, UniProt P55084). AlphaFold-predicted 3D structure; by default coloured by model confidence (blue = very high, orange = very low, typical of disordered regions).
Succinyl-CoA:3-ketoacid coenzyme A transferase 1, mitochondrial (OXCT1) — Succinyl-CoA:3-ketoacid coenzyme A transferase 1, mitochondrial — human protein (gene OXCT1, 520 amino acids, UniProt P55809). AlphaFold-predicted 3D structure; by default coloured by model confidence (blue = very high, orange = very low, typical of disordered regions).
3-keto-steroid reductase/17-beta-hydroxysteroid dehydrogenase 7 (HSD17B7) — 3-keto-steroid reductase/17-beta-hydroxysteroid dehydrogenase 7 — human protein (gene HSD17B7, 341 amino acids, UniProt P56937). AlphaFold-predicted 3D structure; by default coloured by model confidence (blue = very high, orange = very low, typical of disordered regions).
Triosephosphate isomerase (TPI1) — Triosephosphate isomerase — human protein (gene TPI1, 249 amino acids, UniProt P60174). AlphaFold-predicted 3D structure; by default coloured by model confidence (blue = very high, orange = very low, typical of disordered regions).
Alpha-2,8-sialyltransferase 8F (ST8SIA6) — Alpha-2,8-sialyltransferase 8F — human protein (gene ST8SIA6, 398 amino acids, UniProt P61647). AlphaFold-predicted 3D structure; by default coloured by model confidence (blue = very high, orange = very low, typical of disordered regions).
NPC intracellular cholesterol transporter 2 (NPC2) — NPC intracellular cholesterol transporter 2 — human protein (gene NPC2, 151 amino acids, UniProt P61916). AlphaFold-predicted 3D structure; by default coloured by model confidence (blue = very high, orange = very low, typical of disordered regions).
Platelet-activating factor acetylhydrolase IB subunit alpha2 (PAFAH1B2) — Platelet-activating factor acetylhydrolase IB subunit alpha2 — human protein (gene PAFAH1B2, 229 amino acids, UniProt P68402). AlphaFold-predicted 3D structure; by default coloured by model confidence (blue = very high, orange = very low, typical of disordered regions).
Cytochrome P450 4F2 (CYP4F2) — Cytochrome P450 4F2 — human protein (gene CYP4F2, 520 amino acids, UniProt P78329). AlphaFold-predicted 3D structure; by default coloured by model confidence (blue = very high, orange = very low, typical of disordered regions).
Phosphoserine phosphatase (PSPH) — Phosphoserine phosphatase — human protein (gene PSPH, 225 amino acids, UniProt P78330). AlphaFold-predicted 3D structure; by default coloured by model confidence (blue = very high, orange = very low, typical of disordered regions).
Phosphatidylinositol-glycan-specific phospholipase D (GPLD1) — Phosphatidylinositol-glycan-specific phospholipase D — human protein (gene GPLD1, 840 amino acids, UniProt P80108). AlphaFold-predicted 3D structure; by default coloured by model confidence (blue = very high, orange = very low, typical of disordered regions).
11-beta-hydroxysteroid dehydrogenase type 2 (HSD11B2) — 11-beta-hydroxysteroid dehydrogenase type 2 — human protein (gene HSD11B2, 405 amino acids, UniProt P80365). AlphaFold-predicted 3D structure; by default coloured by model confidence (blue = very high, orange = very low, typical of disordered regions).
Hydroxyacyl-thioester dehydratase type 2, mitochondrial (HTD2) — Hydroxyacyl-thioester dehydratase type 2, mitochondrial — human protein (gene HTD2, 168 amino acids, UniProt P86397). AlphaFold-predicted 3D structure; by default coloured by model confidence (blue = very high, orange = very low, typical of disordered regions).
Cytochrome P450 4F8 (CYP4F8) — Cytochrome P450 4F8 — human protein (gene CYP4F8, 520 amino acids, UniProt P98187). AlphaFold-predicted 3D structure; by default coloured by model confidence (blue = very high, orange = very low, typical of disordered regions).
Vigilin (HDLBP) — Vigilin — human protein (gene HDLBP, 1268 amino acids, UniProt Q00341). AlphaFold-predicted 3D structure; by default coloured by model confidence (blue = very high, orange = very low, typical of disordered regions).
1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase beta-2 (PLCB2) — 1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase beta-2 — human protein (gene PLCB2, 1185 amino acids, UniProt Q00722). AlphaFold-predicted 3D structure; by default coloured by model confidence (blue = very high, orange = very low, typical of disordered regions).
Beta-1,4 N-acetylgalactosaminyltransferase 1 (B4GALNT1) — Beta-1,4 N-acetylgalactosaminyltransferase 1 — human protein (gene B4GALNT1, 533 amino acids, UniProt Q00973). AlphaFold-predicted 3D structure; by default coloured by model confidence (blue = very high, orange = very low, typical of disordered regions).
Hydroxymethylglutaryl-CoA synthase, cytoplasmic (HMGCS1) — Hydroxymethylglutaryl-CoA synthase, cytoplasmic — human protein (gene HMGCS1, 520 amino acids, UniProt Q01581). AlphaFold-predicted 3D structure; by default coloured by model confidence (blue = very high, orange = very low, typical of disordered regions).
Inositol polyphosphate 5-phosphatase OCRL (OCRL) — Inositol polyphosphate 5-phosphatase OCRL — human protein (gene OCRL, 901 amino acids, UniProt Q01968). AlphaFold-predicted 3D structure; by default coloured by model confidence (blue = very high, orange = very low, typical of disordered regions).
1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase beta-3 (PLCB3) — 1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase beta-3 — human protein (gene PLCB3, 1234 amino acids, UniProt Q01970). AlphaFold-predicted 3D structure; by default coloured by model confidence (blue = very high, orange = very low, typical of disordered regions).
N-acylethanolamine-hydrolyzing acid amidase (NAAA) — N-acylethanolamine-hydrolyzing acid amidase — human protein (gene NAAA, 359 amino acids, UniProt Q02083). AlphaFold-predicted 3D structure; by default coloured by model confidence (blue = very high, orange = very low, typical of disordered regions).
2-oxoglutarate dehydrogenase complex component E1 (OGDH) — 2-oxoglutarate dehydrogenase complex component E1 — human protein (gene OGDH, 1023 amino acids, UniProt Q02218). AlphaFold-predicted 3D structure; by default coloured by model confidence (blue = very high, orange = very low, typical of disordered regions).