Library › DNA & Proteins › Human proteins (AlphaFold) · Proteases & peptidases

Human proteins (AlphaFold) · Proteases & peptidases: 260 3D models

DNA, RNA, nucleic-acid drugs, gene editing, proteins and 300+ real PDB structures (real sizes 1–100 nm). Each one is a ready-made 3D model you can turn, recolour and place in a figure — open BioDioRama and type its name in the Library search.

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Ciliated left-right organizer metallopeptidase (CIROP) — Ciliated left-right organizer metallopeptidase — human protein (gene CIROP, 788 amino acids, UniProt A0A1B0GTW7). AlphaFold-predicted 3D structure; by default coloured by model confidence (blue = very high, orange = very low, typical of disordered regions).
Proteasome subunit beta type-11 (PSMB11) — Proteasome subunit beta type-11 — human protein (gene PSMB11, 300 amino acids, UniProt A5LHX3). AlphaFold-predicted 3D structure; by default coloured by model confidence (blue = very high, orange = very low, typical of disordered regions).
Metalloprotease TIKI2 (TRABD2B) — Metalloprotease TIKI2 — human protein (gene TRABD2B, 517 amino acids, UniProt A6NFA1). AlphaFold-predicted 3D structure; by default coloured by model confidence (blue = very high, orange = very low, typical of disordered regions).
Putative glutathione hydrolase 3 proenzyme (GGT3P) — Putative glutathione hydrolase 3 proenzyme — human protein (gene GGT3P, 568 amino acids, UniProt A6NGU5). AlphaFold-predicted 3D structure; by default coloured by model confidence (blue = very high, orange = very low, typical of disordered regions).
Ubiquitin carboxyl-terminal hydrolase 27 (USP27X) — Ubiquitin carboxyl-terminal hydrolase 27 — human protein (gene USP27X, 438 amino acids, UniProt A6NNY8). AlphaFold-predicted 3D structure; by default coloured by model confidence (blue = very high, orange = very low, typical of disordered regions).
Calcium-activated chloride channel regulator 1 (CLCA1) — Calcium-activated chloride channel regulator 1 — human protein (gene CLCA1, 914 amino acids, UniProt A8K7I4). AlphaFold-predicted 3D structure; by default coloured by model confidence (blue = very high, orange = very low, typical of disordered regions).
Mannan-binding lectin serine protease 2 (MASP2) — Mannan-binding lectin serine protease 2 — human protein (gene MASP2, 686 amino acids, UniProt O00187). AlphaFold-predicted 3D structure; by default coloured by model confidence (blue = very high, orange = very low, typical of disordered regions).
Eukaryotic translation initiation factor 3 subunit F (EIF3F) — Eukaryotic translation initiation factor 3 subunit F — human protein (gene EIF3F, 357 amino acids, UniProt O00303). AlphaFold-predicted 3D structure; by default coloured by model confidence (blue = very high, orange = very low, typical of disordered regions).
Ubiquitin C-terminal hydrolase PSMD14 (PSMD14) — Ubiquitin C-terminal hydrolase PSMD14 — human protein (gene PSMD14, 310 amino acids, UniProt O00487). AlphaFold-predicted 3D structure; by default coloured by model confidence (blue = very high, orange = very low, typical of disordered regions).
Ubiquitin carboxyl-terminal hydrolase 9Y (USP9Y) — Ubiquitin carboxyl-terminal hydrolase 9Y — human protein (gene USP9Y, 2555 amino acids, UniProt O00507). AlphaFold-predicted 3D structure; by default coloured by model confidence (blue = very high, orange = very low, typical of disordered regions).
Disintegrin and metalloproteinase domain-containing protein 10 (ADAM10) — Disintegrin and metalloproteinase domain-containing protein 10 — human protein (gene ADAM10, 748 amino acids, UniProt O14672). AlphaFold-predicted 3D structure; by default coloured by model confidence (blue = very high, orange = very low, typical of disordered regions).
Tripeptidyl-peptidase 1 (TPP1) — Tripeptidyl-peptidase 1 — human protein (gene TPP1, 563 amino acids, UniProt O14773). AlphaFold-predicted 3D structure; by default coloured by model confidence (blue = very high, orange = very low, typical of disordered regions).
Calpain-9 (CAPN9) — Calpain-9 — human protein (gene CAPN9, 690 amino acids, UniProt O14815). AlphaFold-predicted 3D structure; by default coloured by model confidence (blue = very high, orange = very low, typical of disordered regions).
A disintegrin and metalloproteinase with thrombospondin motifs 3 (ADAMTS3) — A disintegrin and metalloproteinase with thrombospondin motifs 3 — human protein (gene ADAMTS3, 1205 amino acids, UniProt O15072). AlphaFold-predicted 3D structure; by default coloured by model confidence (blue = very high, orange = very low, typical of disordered regions).
ADAM DEC1 (ADAMDEC1) — ADAM DEC1 — human protein (gene ADAMDEC1, 470 amino acids, UniProt O15204). AlphaFold-predicted 3D structure; by default coloured by model confidence (blue = very high, orange = very low, typical of disordered regions).
Transmembrane protease serine 2 (TMPRSS2) — Transmembrane protease serine 2 — human protein (gene TMPRSS2, 492 amino acids, UniProt O15393). AlphaFold-predicted 3D structure; by default coloured by model confidence (blue = very high, orange = very low, typical of disordered regions).
Calpain-5 (CAPN5) — Calpain-5 — human protein (gene CAPN5, 640 amino acids, UniProt O15484). AlphaFold-predicted 3D structure; by default coloured by model confidence (blue = very high, orange = very low, typical of disordered regions).
Disintegrin and metalloproteinase domain-containing protein 12 (ADAM12) — Disintegrin and metalloproteinase domain-containing protein 12 — human protein (gene ADAM12, 909 amino acids, UniProt O43184). AlphaFold-predicted 3D structure; by default coloured by model confidence (blue = very high, orange = very low, typical of disordered regions).
Kallikrein-10 (KLK10) — Kallikrein-10 — human protein (gene KLK10, 276 amino acids, UniProt O43240). AlphaFold-predicted 3D structure; by default coloured by model confidence (blue = very high, orange = very low, typical of disordered regions).
Desert hedgehog protein (DHH) — Desert hedgehog protein — human protein (gene DHH, 396 amino acids, UniProt O43323). AlphaFold-predicted 3D structure; by default coloured by model confidence (blue = very high, orange = very low, typical of disordered regions).
Membrane-bound transcription factor site-2 protease (MBTPS2) — Membrane-bound transcription factor site-2 protease — human protein (gene MBTPS2, 519 amino acids, UniProt O43462). AlphaFold-predicted 3D structure; by default coloured by model confidence (blue = very high, orange = very low, typical of disordered regions).
Serine protease HTRA2, mitochondrial (HTRA2) — Serine protease HTRA2, mitochondrial — human protein (gene HTRA2, 458 amino acids, UniProt O43464). AlphaFold-predicted 3D structure; by default coloured by model confidence (blue = very high, orange = very low, typical of disordered regions).
Disintegrin and metalloproteinase domain-containing protein 20 (ADAM20) — Disintegrin and metalloproteinase domain-containing protein 20 — human protein (gene ADAM20, 726 amino acids, UniProt O43506). AlphaFold-predicted 3D structure; by default coloured by model confidence (blue = very high, orange = very low, typical of disordered regions).
Nardilysin (NRDC) — Nardilysin — human protein (gene NRDC, 1151 amino acids, UniProt O43847). AlphaFold-predicted 3D structure; by default coloured by model confidence (blue = very high, orange = very low, typical of disordered regions).
Xaa-Pro aminopeptidase 2 (XPNPEP2) — Xaa-Pro aminopeptidase 2 — human protein (gene XPNPEP2, 674 amino acids, UniProt O43895). AlphaFold-predicted 3D structure; by default coloured by model confidence (blue = very high, orange = very low, typical of disordered regions).
Tolloid-like protein 1 (TLL1) — Tolloid-like protein 1 — human protein (gene TLL1, 1013 amino acids, UniProt O43897). AlphaFold-predicted 3D structure; by default coloured by model confidence (blue = very high, orange = very low, typical of disordered regions).
Transmembrane protease serine 11D (TMPRSS11D) — Transmembrane protease serine 11D — human protein (gene TMPRSS11D, 418 amino acids, UniProt O60235). AlphaFold-predicted 3D structure; by default coloured by model confidence (blue = very high, orange = very low, typical of disordered regions).
Kallikrein-8 (KLK8) — Kallikrein-8 — human protein (gene KLK8, 260 amino acids, UniProt O60259). AlphaFold-predicted 3D structure; by default coloured by model confidence (blue = very high, orange = very low, typical of disordered regions).
Matrix metalloproteinase-20 (MMP20) — Matrix metalloproteinase-20 — human protein (gene MMP20, 483 amino acids, UniProt O60882). AlphaFold-predicted 3D structure; by default coloured by model confidence (blue = very high, orange = very low, typical of disordered regions).
Cathepsin L2 (CTSV) — Cathepsin L2 — human protein (gene CTSV, 334 amino acids, UniProt O60911). AlphaFold-predicted 3D structure; by default coloured by model confidence (blue = very high, orange = very low, typical of disordered regions).
A disintegrin and metalloproteinase with thrombospondin motifs 4 (ADAMTS4) — A disintegrin and metalloproteinase with thrombospondin motifs 4 — human protein (gene ADAMTS4, 837 amino acids, UniProt O75173). AlphaFold-predicted 3D structure; by default coloured by model confidence (blue = very high, orange = very low, typical of disordered regions).
Ubiquitin carboxyl-terminal hydrolase 12 (USP12) — Ubiquitin carboxyl-terminal hydrolase 12 — human protein (gene USP12, 370 amino acids, UniProt O75317). AlphaFold-predicted 3D structure; by default coloured by model confidence (blue = very high, orange = very low, typical of disordered regions).
Mitochondrial-processing peptidase subunit beta (PMPCB) — Mitochondrial-processing peptidase subunit beta — human protein (gene PMPCB, 489 amino acids, UniProt O75439). AlphaFold-predicted 3D structure; by default coloured by model confidence (blue = very high, orange = very low, typical of disordered regions).
Ubiquitin carboxyl-terminal hydrolase 2 (USP2) — Ubiquitin carboxyl-terminal hydrolase 2 — human protein (gene USP2, 605 amino acids, UniProt O75604). AlphaFold-predicted 3D structure; by default coloured by model confidence (blue = very high, orange = very low, typical of disordered regions).
Rhomboid-related protein 1 (RHBDL1) — Rhomboid-related protein 1 — human protein (gene RHBDL1, 438 amino acids, UniProt O75783). AlphaFold-predicted 3D structure; by default coloured by model confidence (blue = very high, orange = very low, typical of disordered regions).
Calpain-15 (CAPN15) — Calpain-15 — human protein (gene CAPN15, 1086 amino acids, UniProt O75808). AlphaFold-predicted 3D structure; by default coloured by model confidence (blue = very high, orange = very low, typical of disordered regions).
CAAX prenyl protease 1 homolog (ZMPSTE24) — CAAX prenyl protease 1 homolog — human protein (gene ZMPSTE24, 475 amino acids, UniProt O75844). AlphaFold-predicted 3D structure; by default coloured by model confidence (blue = very high, orange = very low, typical of disordered regions).
Matrix metalloproteinase-23 (MMP23B) — Matrix metalloproteinase-23 — human protein (gene MMP23B, 390 amino acids, UniProt O75900). AlphaFold-predicted 3D structure; by default coloured by model confidence (blue = very high, orange = very low, typical of disordered regions).
Carboxypeptidase D (CPD) — Carboxypeptidase D — human protein (gene CPD, 1380 amino acids, UniProt O75976). AlphaFold-predicted 3D structure; by default coloured by model confidence (blue = very high, orange = very low, typical of disordered regions).
Ubiquitin carboxyl-terminal hydrolase 1 (USP1) — Ubiquitin carboxyl-terminal hydrolase 1 — human protein (gene USP1, 785 amino acids, UniProt O94782). AlphaFold-predicted 3D structure; by default coloured by model confidence (blue = very high, orange = very low, typical of disordered regions).
Ubiquitin carboxyl-terminal hydrolase 19 (USP19) — Ubiquitin carboxyl-terminal hydrolase 19 — human protein (gene USP19, 1318 amino acids, UniProt O94966). AlphaFold-predicted 3D structure; by default coloured by model confidence (blue = very high, orange = very low, typical of disordered regions).
A disintegrin and metalloproteinase with thrombospondin motifs 2 (ADAMTS2) — A disintegrin and metalloproteinase with thrombospondin motifs 2 — human protein (gene ADAMTS2, 1211 amino acids, UniProt O95450). AlphaFold-predicted 3D structure; by default coloured by model confidence (blue = very high, orange = very low, typical of disordered regions).
STAM-binding protein (STAMBP) — STAM-binding protein — human protein (gene STAMBP, 424 amino acids, UniProt O95630). AlphaFold-predicted 3D structure; by default coloured by model confidence (blue = very high, orange = very low, typical of disordered regions).
Endothelin-converting enzyme-like 1 (ECEL1) — Endothelin-converting enzyme-like 1 — human protein (gene ECEL1, 775 amino acids, UniProt O95672). AlphaFold-predicted 3D structure; by default coloured by model confidence (blue = very high, orange = very low, typical of disordered regions).
Napsin-A (NAPSA) — Napsin-A — human protein (gene NAPSA, 420 amino acids, UniProt O96009). AlphaFold-predicted 3D structure; by default coloured by model confidence (blue = very high, orange = very low, typical of disordered regions).
Prothrombin (F2) — Prothrombin — human protein (gene F2, 622 amino acids, UniProt P00734). AlphaFold-predicted 3D structure; by default coloured by model confidence (blue = very high, orange = very low, typical of disordered regions).
Complement C1r subcomponent (C1R) — Complement C1r subcomponent — human protein (gene C1R, 705 amino acids, UniProt P00736). AlphaFold-predicted 3D structure; by default coloured by model confidence (blue = very high, orange = very low, typical of disordered regions).
Coagulation factor IX (F9) — Coagulation factor IX — human protein (gene F9, 461 amino acids, UniProt P00740). AlphaFold-predicted 3D structure; by default coloured by model confidence (blue = very high, orange = very low, typical of disordered regions).
Coagulation factor X (F10) — Coagulation factor X — human protein (gene F10, 488 amino acids, UniProt P00742). AlphaFold-predicted 3D structure; by default coloured by model confidence (blue = very high, orange = very low, typical of disordered regions).
Complement factor D (CFD) — Complement factor D — human protein (gene CFD, 253 amino acids, UniProt P00746). AlphaFold-predicted 3D structure; by default coloured by model confidence (blue = very high, orange = very low, typical of disordered regions).
Plasminogen [Cleaved into: Plasmin (PLG) — Plasminogen [Cleaved into: Plasmin — human protein (gene PLG, 810 amino acids, UniProt P00747). AlphaFold-predicted 3D structure; by default coloured by model confidence (blue = very high, orange = very low, typical of disordered regions).
Coagulation factor XII (F12) — Coagulation factor XII — human protein (gene F12, 615 amino acids, UniProt P00748). AlphaFold-predicted 3D structure; by default coloured by model confidence (blue = very high, orange = very low, typical of disordered regions).
Urokinase-type plasminogen activator (PLAU) — Urokinase-type plasminogen activator — human protein (gene PLAU, 431 amino acids, UniProt P00749). AlphaFold-predicted 3D structure; by default coloured by model confidence (blue = very high, orange = very low, typical of disordered regions).
Tissue-type plasminogen activator (PLAT) — Tissue-type plasminogen activator — human protein (gene PLAT, 562 amino acids, UniProt P00750). AlphaFold-predicted 3D structure; by default coloured by model confidence (blue = very high, orange = very low, typical of disordered regions).
Complement factor B (CFB) — Complement factor B — human protein (gene CFB, 764 amino acids, UniProt P00751). AlphaFold-predicted 3D structure; by default coloured by model confidence (blue = very high, orange = very low, typical of disordered regions).
Renin (REN) — Renin — human protein (gene REN, 406 amino acids, UniProt P00797). AlphaFold-predicted 3D structure; by default coloured by model confidence (blue = very high, orange = very low, typical of disordered regions).
Lactotransferrin (LTF) — Lactotransferrin — human protein (gene LTF, 710 amino acids, UniProt P02788). AlphaFold-predicted 3D structure; by default coloured by model confidence (blue = very high, orange = very low, typical of disordered regions).
Coagulation factor XI (F11) — Coagulation factor XI — human protein (gene F11, 625 amino acids, UniProt P03951). AlphaFold-predicted 3D structure; by default coloured by model confidence (blue = very high, orange = very low, typical of disordered regions).
Plasma kallikrein (KLKB1) — Plasma kallikrein — human protein (gene KLKB1, 638 amino acids, UniProt P03952). AlphaFold-predicted 3D structure; by default coloured by model confidence (blue = very high, orange = very low, typical of disordered regions).
Interstitial collagenase (MMP1) — Interstitial collagenase — human protein (gene MMP1, 469 amino acids, UniProt P03956). AlphaFold-predicted 3D structure; by default coloured by model confidence (blue = very high, orange = very low, typical of disordered regions).
Vitamin K-dependent protein C (PROC) — Vitamin K-dependent protein C — human protein (gene PROC, 461 amino acids, UniProt P04070). AlphaFold-predicted 3D structure; by default coloured by model confidence (blue = very high, orange = very low, typical of disordered regions).
Complement factor I (CFI) — Complement factor I — human protein (gene CFI, 583 amino acids, UniProt P05156). AlphaFold-predicted 3D structure; by default coloured by model confidence (blue = very high, orange = very low, typical of disordered regions).
Serine protease hepsin (HPN) — Serine protease hepsin — human protein (gene HPN, 417 amino acids, UniProt P05981). AlphaFold-predicted 3D structure; by default coloured by model confidence (blue = very high, orange = very low, typical of disordered regions).
Complement C2 (C2) — Complement C2 — human protein (gene C2, 752 amino acids, UniProt P06681). AlphaFold-predicted 3D structure; by default coloured by model confidence (blue = very high, orange = very low, typical of disordered regions).
Kallikrein-1 (KLK1) — Kallikrein-1 — human protein (gene KLK1, 262 amino acids, UniProt P06870). AlphaFold-predicted 3D structure; by default coloured by model confidence (blue = very high, orange = very low, typical of disordered regions).
Prostate-specific antigen (KLK3) — Prostate-specific antigen — human protein (gene KLK3, 261 amino acids, UniProt P07288). AlphaFold-predicted 3D structure; by default coloured by model confidence (blue = very high, orange = very low, typical of disordered regions).
Cathepsin D (CTSD) — Cathepsin D — human protein (gene CTSD, 412 amino acids, UniProt P07339). AlphaFold-predicted 3D structure; by default coloured by model confidence (blue = very high, orange = very low, typical of disordered regions).
Calpain-1 catalytic subunit (CAPN1) — Calpain-1 catalytic subunit — human protein (gene CAPN1, 714 amino acids, UniProt P07384). AlphaFold-predicted 3D structure; by default coloured by model confidence (blue = very high, orange = very low, typical of disordered regions).
Serine protease 1 (PRSS1) — Serine protease 1 — human protein (gene PRSS1, 247 amino acids, UniProt P07477). AlphaFold-predicted 3D structure; by default coloured by model confidence (blue = very high, orange = very low, typical of disordered regions).
Trypsin-2 (PRSS2) — Trypsin-2 — human protein (gene PRSS2, 247 amino acids, UniProt P07478). AlphaFold-predicted 3D structure; by default coloured by model confidence (blue = very high, orange = very low, typical of disordered regions).
Procathepsin L (CTSL) — Procathepsin L — human protein (gene CTSL, 333 amino acids, UniProt P07711). AlphaFold-predicted 3D structure; by default coloured by model confidence (blue = very high, orange = very low, typical of disordered regions).
Cathepsin B (CTSB) — Cathepsin B — human protein (gene CTSB, 339 amino acids, UniProt P07858). AlphaFold-predicted 3D structure; by default coloured by model confidence (blue = very high, orange = very low, typical of disordered regions).
Chymotrypsin-like elastase family member 2A (CELA2A) — Chymotrypsin-like elastase family member 2A — human protein (gene CELA2A, 269 amino acids, UniProt P08217). AlphaFold-predicted 3D structure; by default coloured by model confidence (blue = very high, orange = very low, typical of disordered regions).
Chymotrypsin-like elastase family member 2B (CELA2B) — Chymotrypsin-like elastase family member 2B — human protein (gene CELA2B, 269 amino acids, UniProt P08218). AlphaFold-predicted 3D structure; by default coloured by model confidence (blue = very high, orange = very low, typical of disordered regions).
Neutrophil elastase (ELANE) — Neutrophil elastase — human protein (gene ELANE, 267 amino acids, UniProt P08246). AlphaFold-predicted 3D structure; by default coloured by model confidence (blue = very high, orange = very low, typical of disordered regions).
72 kDa type IV collagenase (MMP2) — 72 kDa type IV collagenase — human protein (gene MMP2, 660 amino acids, UniProt P08253). AlphaFold-predicted 3D structure; by default coloured by model confidence (blue = very high, orange = very low, typical of disordered regions).
Stromelysin-1 (MMP3) — Stromelysin-1 — human protein (gene MMP3, 477 amino acids, UniProt P08254). AlphaFold-predicted 3D structure; by default coloured by model confidence (blue = very high, orange = very low, typical of disordered regions).
Cathepsin G (CTSG) — Cathepsin G — human protein (gene CTSG, 255 amino acids, UniProt P08311). AlphaFold-predicted 3D structure; by default coloured by model confidence (blue = very high, orange = very low, typical of disordered regions).
Neprilysin (MME) — Neprilysin — human protein (gene MME, 750 amino acids, UniProt P08473). AlphaFold-predicted 3D structure; by default coloured by model confidence (blue = very high, orange = very low, typical of disordered regions).
Apolipoprotein(a) (LPA) — Apolipoprotein(a) — human protein (gene LPA, 2040 amino acids, UniProt P08519). AlphaFold-predicted 3D structure; by default coloured by model confidence (blue = very high, orange = very low, typical of disordered regions).
Coagulation factor VII (F7) — Coagulation factor VII — human protein (gene F7, 466 amino acids, UniProt P08709). AlphaFold-predicted 3D structure; by default coloured by model confidence (blue = very high, orange = very low, typical of disordered regions).
Chymotrypsin-like elastase family member 3B (CELA3B) — Chymotrypsin-like elastase family member 3B — human protein (gene CELA3B, 270 amino acids, UniProt P08861). AlphaFold-predicted 3D structure; by default coloured by model confidence (blue = very high, orange = very low, typical of disordered regions).
Matrilysin (MMP7) — Matrilysin — human protein (gene MMP7, 267 amino acids, UniProt P09237). AlphaFold-predicted 3D structure; by default coloured by model confidence (blue = very high, orange = very low, typical of disordered regions).
Stromelysin-2 (MMP10) — Stromelysin-2 — human protein (gene MMP10, 476 amino acids, UniProt P09238). AlphaFold-predicted 3D structure; by default coloured by model confidence (blue = very high, orange = very low, typical of disordered regions).
Pro-cathepsin H [Cleaved into: Cathepsin H mini chain; Cathepsin H (CTSH) — Pro-cathepsin H [Cleaved into: Cathepsin H mini chain; Cathepsin H — human protein (gene CTSH, 335 amino acids, UniProt P09668). AlphaFold-predicted 3D structure; by default coloured by model confidence (blue = very high, orange = very low, typical of disordered regions).
Complement C1s subcomponent (C1S) — Complement C1s subcomponent — human protein (gene C1S, 688 amino acids, UniProt P09871). AlphaFold-predicted 3D structure; by default coloured by model confidence (blue = very high, orange = very low, typical of disordered regions).
Ubiquitin carboxyl-terminal hydrolase isozyme L1 (UCHL1) — Ubiquitin carboxyl-terminal hydrolase isozyme L1 — human protein (gene UCHL1, 223 amino acids, UniProt P09936). AlphaFold-predicted 3D structure; by default coloured by model confidence (blue = very high, orange = very low, typical of disordered regions).
Furin (FURIN) — Furin — human protein (gene FURIN, 794 amino acids, UniProt P09958). AlphaFold-predicted 3D structure; by default coloured by model confidence (blue = very high, orange = very low, typical of disordered regions).
Leukotriene A-4 hydrolase (LTA4H) — Leukotriene A-4 hydrolase — human protein (gene LTA4H, 611 amino acids, UniProt P09960). AlphaFold-predicted 3D structure; by default coloured by model confidence (blue = very high, orange = very low, typical of disordered regions).
Bifunctional peptidase and (JMJD7) — Bifunctional peptidase and — human protein (gene JMJD7, 316 amino acids, UniProt P0C870). AlphaFold-predicted 3D structure; by default coloured by model confidence (blue = very high, orange = very low, typical of disordered regions).
Serine protease 56 (PRSS56) — Serine protease 56 — human protein (gene PRSS56, 603 amino acids, UniProt P0CW18). AlphaFold-predicted 3D structure; by default coloured by model confidence (blue = very high, orange = very low, typical of disordered regions).
Pepsin A-4 (PGA4) — Pepsin A-4 — human protein (gene PGA4, 388 amino acids, UniProt P0DJD7). AlphaFold-predicted 3D structure; by default coloured by model confidence (blue = very high, orange = very low, typical of disordered regions).
Pepsin A-3 (PGA3) — Pepsin A-3 — human protein (gene PGA3, 388 amino acids, UniProt P0DJD8). AlphaFold-predicted 3D structure; by default coloured by model confidence (blue = very high, orange = very low, typical of disordered regions).
Pepsin A-5 (PGA5) — Pepsin A-5 — human protein (gene PGA5, 388 amino acids, UniProt P0DJD9). AlphaFold-predicted 3D structure; by default coloured by model confidence (blue = very high, orange = very low, typical of disordered regions).
Endothelin-converting enzyme 2 (ECE2) — Endothelin-converting enzyme 2 — human protein (gene ECE2, 811 amino acids, UniProt P0DPD6). AlphaFold-predicted 3D structure; by default coloured by model confidence (blue = very high, orange = very low, typical of disordered regions).
EEF1AKMT4-ECE2 readthrough transcript protein (EEF1AKMT4-ECE2) — EEF1AKMT4-ECE2 readthrough transcript protein — human protein (gene EEF1AKMT4-ECE2, 883 amino acids, UniProt P0DPD8). AlphaFold-predicted 3D structure; by default coloured by model confidence (blue = very high, orange = very low, typical of disordered regions).
Granzyme B (GZMB) — Granzyme B — human protein (gene GZMB, 247 amino acids, UniProt P10144). AlphaFold-predicted 3D structure; by default coloured by model confidence (blue = very high, orange = very low, typical of disordered regions).
Endogenous retrovirus group K member 10 Pro protein (ERVK-10) — Endogenous retrovirus group K member 10 Pro protein — human protein (gene ERVK-10, 156 amino acids, UniProt P10265). AlphaFold-predicted 3D structure; by default coloured by model confidence (blue = very high, orange = very low, typical of disordered regions).
Acrosin (ACR) — Acrosin — human protein (gene ACR, 421 amino acids, UniProt P10323). AlphaFold-predicted 3D structure; by default coloured by model confidence (blue = very high, orange = very low, typical of disordered regions).
Lysosomal protective protein (CTSA) — Lysosomal protective protein — human protein (gene CTSA, 480 amino acids, UniProt P10619). AlphaFold-predicted 3D structure; by default coloured by model confidence (blue = very high, orange = very low, typical of disordered regions).
Granzyme A (GZMA) — Granzyme A — human protein (gene GZMA, 262 amino acids, UniProt P12544). AlphaFold-predicted 3D structure; by default coloured by model confidence (blue = very high, orange = very low, typical of disordered regions).
Angiotensin-converting enzyme (ACE) — Angiotensin-converting enzyme — human protein (gene ACE, 1306 amino acids, UniProt P12821). AlphaFold-predicted 3D structure; by default coloured by model confidence (blue = very high, orange = very low, typical of disordered regions).
Xaa-Pro dipeptidase (PEPD) — Xaa-Pro dipeptidase — human protein (gene PEPD, 493 amino acids, UniProt P12955). AlphaFold-predicted 3D structure; by default coloured by model confidence (blue = very high, orange = very low, typical of disordered regions).
Bone morphogenetic protein 1 (BMP1) — Bone morphogenetic protein 1 — human protein (gene BMP1, 986 amino acids, UniProt P13497). AlphaFold-predicted 3D structure; by default coloured by model confidence (blue = very high, orange = very low, typical of disordered regions).
Cathepsin E (CTSE) — Cathepsin E — human protein (gene CTSE, 396 amino acids, UniProt P14091). AlphaFold-predicted 3D structure; by default coloured by model confidence (blue = very high, orange = very low, typical of disordered regions).
Carboxypeptidase M (CPM) — Carboxypeptidase M — human protein (gene CPM, 443 amino acids, UniProt P14384). AlphaFold-predicted 3D structure; by default coloured by model confidence (blue = very high, orange = very low, typical of disordered regions).
Insulin-degrading enzyme (IDE) — Insulin-degrading enzyme — human protein (gene IDE, 1019 amino acids, UniProt P14735). AlphaFold-predicted 3D structure; by default coloured by model confidence (blue = very high, orange = very low, typical of disordered regions).
Matrix metalloproteinase-9 (MMP9) — Matrix metalloproteinase-9 — human protein (gene MMP9, 707 amino acids, UniProt P14780). AlphaFold-predicted 3D structure; by default coloured by model confidence (blue = very high, orange = very low, typical of disordered regions).
Carboxypeptidase A1 (CPA1) — Carboxypeptidase A1 — human protein (gene CPA1, 419 amino acids, UniProt P15085). AlphaFold-predicted 3D structure; by default coloured by model confidence (blue = very high, orange = very low, typical of disordered regions).
Carboxypeptidase B (CPB1) — Carboxypeptidase B — human protein (gene CPB1, 417 amino acids, UniProt P15086). AlphaFold-predicted 3D structure; by default coloured by model confidence (blue = very high, orange = very low, typical of disordered regions).
Aminopeptidase N (ANPEP) — Aminopeptidase N — human protein (gene ANPEP, 967 amino acids, UniProt P15144). AlphaFold-predicted 3D structure; by default coloured by model confidence (blue = very high, orange = very low, typical of disordered regions).
Carboxypeptidase N catalytic chain (CPN1) — Carboxypeptidase N catalytic chain — human protein (gene CPN1, 458 amino acids, UniProt P15169). AlphaFold-predicted 3D structure; by default coloured by model confidence (blue = very high, orange = very low, typical of disordered regions).
Ubiquitin carboxyl-terminal hydrolase isozyme L3 (UCHL3) — Ubiquitin carboxyl-terminal hydrolase isozyme L3 — human protein (gene UCHL3, 230 amino acids, UniProt P15374). AlphaFold-predicted 3D structure; by default coloured by model confidence (blue = very high, orange = very low, typical of disordered regions).
Dipeptidase 1 (DPEP1) — Dipeptidase 1 — human protein (gene DPEP1, 411 amino acids, UniProt P16444). AlphaFold-predicted 3D structure; by default coloured by model confidence (blue = very high, orange = very low, typical of disordered regions).
Neuroendocrine convertase 2 (PCSK2) — Neuroendocrine convertase 2 — human protein (gene PCSK2, 638 amino acids, UniProt P16519). AlphaFold-predicted 3D structure; by default coloured by model confidence (blue = very high, orange = very low, typical of disordered regions).
Carboxypeptidase E (CPE) — Carboxypeptidase E — human protein (gene CPE, 476 amino acids, UniProt P16870). AlphaFold-predicted 3D structure; by default coloured by model confidence (blue = very high, orange = very low, typical of disordered regions).
Calpain-2 catalytic subunit (CAPN2) — Calpain-2 catalytic subunit — human protein (gene CAPN2, 700 amino acids, UniProt P17655). AlphaFold-predicted 3D structure; by default coloured by model confidence (blue = very high, orange = very low, typical of disordered regions).
Glutathione hydrolase 1 proenzyme (GGT1) — Glutathione hydrolase 1 proenzyme — human protein (gene GGT1, 569 amino acids, UniProt P19440). AlphaFold-predicted 3D structure; by default coloured by model confidence (blue = very high, orange = very low, typical of disordered regions).
Gastricsin (PGC) — Gastricsin — human protein (gene PGC, 388 amino acids, UniProt P20142). AlphaFold-predicted 3D structure; by default coloured by model confidence (blue = very high, orange = very low, typical of disordered regions).
Kallikrein-2 (KLK2) — Kallikrein-2 — human protein (gene KLK2, 261 amino acids, UniProt P20151). AlphaFold-predicted 3D structure; by default coloured by model confidence (blue = very high, orange = very low, typical of disordered regions).
Tryptase beta-2 (TPSB2) — Tryptase beta-2 — human protein (gene TPSB2, 275 amino acids, UniProt P20231). AlphaFold-predicted 3D structure; by default coloured by model confidence (blue = very high, orange = very low, typical of disordered regions).
Granzyme H (GZMH) — Granzyme H — human protein (gene GZMH, 246 amino acids, UniProt P20718). AlphaFold-predicted 3D structure; by default coloured by model confidence (blue = very high, orange = very low, typical of disordered regions).
Calpain-3 (CAPN3) — Calpain-3 — human protein (gene CAPN3, 821 amino acids, UniProt P20807). AlphaFold-predicted 3D structure; by default coloured by model confidence (blue = very high, orange = very low, typical of disordered regions).
N(4)-(beta-N-acetylglucosaminyl)-L-asparaginase (AGA) — N(4)-(beta-N-acetylglucosaminyl)-L-asparaginase — human protein (gene AGA, 346 amino acids, UniProt P20933). AlphaFold-predicted 3D structure; by default coloured by model confidence (blue = very high, orange = very low, typical of disordered regions).
Tumor necrosis factor alpha-induced protein 3 (TNFAIP3) — Tumor necrosis factor alpha-induced protein 3 — human protein (gene TNFAIP3, 790 amino acids, UniProt P21580). AlphaFold-predicted 3D structure; by default coloured by model confidence (blue = very high, orange = very low, typical of disordered regions).
Protein-glutamine gamma-glutamyltransferase 2 (TGM2) — Protein-glutamine gamma-glutamyltransferase 2 — human protein (gene TGM2, 687 amino acids, UniProt P21980). AlphaFold-predicted 3D structure; by default coloured by model confidence (blue = very high, orange = very low, typical of disordered regions).
Neutrophil collagenase (MMP8) — Neutrophil collagenase — human protein (gene MMP8, 467 amino acids, UniProt P22894). AlphaFold-predicted 3D structure; by default coloured by model confidence (blue = very high, orange = very low, typical of disordered regions).
Kell blood group glycoprotein (KEL) — Kell blood group glycoprotein — human protein (gene KEL, 732 amino acids, UniProt P23276). AlphaFold-predicted 3D structure; by default coloured by model confidence (blue = very high, orange = very low, typical of disordered regions).
Chymase (CMA1) — Chymase — human protein (gene CMA1, 247 amino acids, UniProt P23946). AlphaFold-predicted 3D structure; by default coloured by model confidence (blue = very high, orange = very low, typical of disordered regions).
Myeloblastin (PRTN3) — Myeloblastin — human protein (gene PRTN3, 256 amino acids, UniProt P24158). AlphaFold-predicted 3D structure; by default coloured by model confidence (blue = very high, orange = very low, typical of disordered regions).
Stromelysin-3 (MMP11) — Stromelysin-3 — human protein (gene MMP11, 488 amino acids, UniProt P24347). AlphaFold-predicted 3D structure; by default coloured by model confidence (blue = very high, orange = very low, typical of disordered regions).
Cathepsin S (CTSS) — Cathepsin S — human protein (gene CTSS, 331 amino acids, UniProt P25774). AlphaFold-predicted 3D structure; by default coloured by model confidence (blue = very high, orange = very low, typical of disordered regions).
Dipeptidyl peptidase 4 (DPP4) — Dipeptidyl peptidase 4 — human protein (gene DPP4, 766 amino acids, UniProt P27487). AlphaFold-predicted 3D structure; by default coloured by model confidence (blue = very high, orange = very low, typical of disordered regions).
Proteasome subunit beta type-8 (PSMB8) — Proteasome subunit beta type-8 — human protein (gene PSMB8, 276 amino acids, UniProt P28062). AlphaFold-predicted 3D structure; by default coloured by model confidence (blue = very high, orange = very low, typical of disordered regions).
Proteasome subunit beta type-9 (PSMB9) — Proteasome subunit beta type-9 — human protein (gene PSMB9, 219 amino acids, UniProt P28065). AlphaFold-predicted 3D structure; by default coloured by model confidence (blue = very high, orange = very low, typical of disordered regions).
Proteasome subunit beta type-6 (PSMB6) — Proteasome subunit beta type-6 — human protein (gene PSMB6, 239 amino acids, UniProt P28072). AlphaFold-predicted 3D structure; by default coloured by model confidence (blue = very high, orange = very low, typical of disordered regions).
Proteasome subunit beta type-5 (PSMB5) — Proteasome subunit beta type-5 — human protein (gene PSMB5, 263 amino acids, UniProt P28074). AlphaFold-predicted 3D structure; by default coloured by model confidence (blue = very high, orange = very low, typical of disordered regions).
Cytosol aminopeptidase (LAP3) — Cytosol aminopeptidase — human protein (gene LAP3, 519 amino acids, UniProt P28838). AlphaFold-predicted 3D structure; by default coloured by model confidence (blue = very high, orange = very low, typical of disordered regions).
Neuroendocrine convertase 1 (PCSK1) — Neuroendocrine convertase 1 — human protein (gene PCSK1, 753 amino acids, UniProt P29120). AlphaFold-predicted 3D structure; by default coloured by model confidence (blue = very high, orange = very low, typical of disordered regions).
Proprotein convertase subtilisin/kexin type 6 (PCSK6) — Proprotein convertase subtilisin/kexin type 6 — human protein (gene PCSK6, 969 amino acids, UniProt P29122). AlphaFold-predicted 3D structure; by default coloured by model confidence (blue = very high, orange = very low, typical of disordered regions).
Tripeptidyl-peptidase 2 (TPP2) — Tripeptidyl-peptidase 2 — human protein (gene TPP2, 1249 amino acids, UniProt P29144). AlphaFold-predicted 3D structure; by default coloured by model confidence (blue = very high, orange = very low, typical of disordered regions).
Caspase-1 (CASP1) — Caspase-1 — human protein (gene CASP1, 404 amino acids, UniProt P29466). AlphaFold-predicted 3D structure; by default coloured by model confidence (blue = very high, orange = very low, typical of disordered regions).
Caspase-14 (CASP14) — Caspase-14 — human protein (gene CASP14, 242 amino acids, UniProt P31944). AlphaFold-predicted 3D structure; by default coloured by model confidence (blue = very high, orange = very low, typical of disordered regions).
Trypsin-3 (PRSS3) — Trypsin-3 — human protein (gene PRSS3, 304 amino acids, UniProt P35030). AlphaFold-predicted 3D structure; by default coloured by model confidence (blue = very high, orange = very low, typical of disordered regions).
Ubiquitin carboxyl-terminal hydrolase 6 (USP6) — Ubiquitin carboxyl-terminal hydrolase 6 — human protein (gene USP6, 1406 amino acids, UniProt P35125). AlphaFold-predicted 3D structure; by default coloured by model confidence (blue = very high, orange = very low, typical of disordered regions).
Glutathione hydrolase 5 proenzyme (GGT5) — Glutathione hydrolase 5 proenzyme — human protein (gene GGT5, 586 amino acids, UniProt P36269). AlphaFold-predicted 3D structure; by default coloured by model confidence (blue = very high, orange = very low, typical of disordered regions).
Lon protease homolog, mitochondrial (LONP1) — Lon protease homolog, mitochondrial — human protein (gene LONP1, 959 amino acids, UniProt P36776). AlphaFold-predicted 3D structure; by default coloured by model confidence (blue = very high, orange = very low, typical of disordered regions).
Macrophage metalloelastase (MMP12) — Macrophage metalloelastase — human protein (gene MMP12, 470 amino acids, UniProt P39900). AlphaFold-predicted 3D structure; by default coloured by model confidence (blue = very high, orange = very low, typical of disordered regions).
Proteasome subunit beta type-10 (PSMB10) — Proteasome subunit beta type-10 — human protein (gene PSMB10, 273 amino acids, UniProt P40306). AlphaFold-predicted 3D structure; by default coloured by model confidence (blue = very high, orange = very low, typical of disordered regions).
Ubiquitin carboxyl-terminal hydrolase 8 (USP8) — Ubiquitin carboxyl-terminal hydrolase 8 — human protein (gene USP8, 1118 amino acids, UniProt P40818). AlphaFold-predicted 3D structure; by default coloured by model confidence (blue = very high, orange = very low, typical of disordered regions).
Caspase-3 (CASP3) — Caspase-3 — human protein (gene CASP3, 277 amino acids, UniProt P42574). AlphaFold-predicted 3D structure; by default coloured by model confidence (blue = very high, orange = very low, typical of disordered regions).
Caspase-2 (CASP2) — Caspase-2 — human protein (gene CASP2, 452 amino acids, UniProt P42575). AlphaFold-predicted 3D structure; by default coloured by model confidence (blue = very high, orange = very low, typical of disordered regions).
Lysosomal Pro-X carboxypeptidase (PRCP) — Lysosomal Pro-X carboxypeptidase — human protein (gene PRCP, 496 amino acids, UniProt P42785). AlphaFold-predicted 3D structure; by default coloured by model confidence (blue = very high, orange = very low, typical of disordered regions).
Endothelin-converting enzyme 1 (ECE1) — Endothelin-converting enzyme 1 — human protein (gene ECE1, 770 amino acids, UniProt P42892). AlphaFold-predicted 3D structure; by default coloured by model confidence (blue = very high, orange = very low, typical of disordered regions).
Cathepsin O (CTSO) — Cathepsin O — human protein (gene CTSO, 321 amino acids, UniProt P43234). AlphaFold-predicted 3D structure; by default coloured by model confidence (blue = very high, orange = very low, typical of disordered regions).
Cathepsin K (CTSK) — Cathepsin K — human protein (gene CTSK, 329 amino acids, UniProt P43235). AlphaFold-predicted 3D structure; by default coloured by model confidence (blue = very high, orange = very low, typical of disordered regions).
Collagenase 3 (MMP13) — Collagenase 3 — human protein (gene MMP13, 471 amino acids, UniProt P45452). AlphaFold-predicted 3D structure; by default coloured by model confidence (blue = very high, orange = very low, typical of disordered regions).
Ubiquitin carboxyl-terminal hydrolase 5 (USP5) — Ubiquitin carboxyl-terminal hydrolase 5 — human protein (gene USP5, 858 amino acids, UniProt P45974). AlphaFold-predicted 3D structure; by default coloured by model confidence (blue = very high, orange = very low, typical of disordered regions).
Lys-63-specific deubiquitinase BRCC36 (BRCC3) — Lys-63-specific deubiquitinase BRCC36 — human protein (gene BRCC3, 316 amino acids, UniProt P46736). AlphaFold-predicted 3D structure; by default coloured by model confidence (blue = very high, orange = very low, typical of disordered regions).
Carboxypeptidase A2 (CPA2) — Carboxypeptidase A2 — human protein (gene CPA2, 419 amino acids, UniProt P48052). AlphaFold-predicted 3D structure; by default coloured by model confidence (blue = very high, orange = very low, typical of disordered regions).
Prolyl endopeptidase (PREP) — Prolyl endopeptidase — human protein (gene PREP, 710 amino acids, UniProt P48147). AlphaFold-predicted 3D structure; by default coloured by model confidence (blue = very high, orange = very low, typical of disordered regions).
Mannan-binding lectin serine protease 1 (MASP1) — Mannan-binding lectin serine protease 1 — human protein (gene MASP1, 699 amino acids, UniProt P48740). AlphaFold-predicted 3D structure; by default coloured by model confidence (blue = very high, orange = very low, typical of disordered regions).
Caspase-4 (CASP4) — Caspase-4 — human protein (gene CASP4, 377 amino acids, UniProt P49662). AlphaFold-predicted 3D structure; by default coloured by model confidence (blue = very high, orange = very low, typical of disordered regions).
Presenilin-1 (PSEN1) — Presenilin-1 — human protein (gene PSEN1, 467 amino acids, UniProt P49768). AlphaFold-predicted 3D structure; by default coloured by model confidence (blue = very high, orange = very low, typical of disordered regions).
Adenosine 5'-monophosphoramidase HINT1 (HINT1) — Adenosine 5'-monophosphoramidase HINT1 — human protein (gene HINT1, 126 amino acids, UniProt P49773). AlphaFold-predicted 3D structure; by default coloured by model confidence (blue = very high, orange = very low, typical of disordered regions).
Presenilin-2 (PSEN2) — Presenilin-2 — human protein (gene PSEN2, 448 amino acids, UniProt P49810). AlphaFold-predicted 3D structure; by default coloured by model confidence (blue = very high, orange = very low, typical of disordered regions).
Kallikrein-7 (KLK7) — Kallikrein-7 — human protein (gene KLK7, 253 amino acids, UniProt P49862). AlphaFold-predicted 3D structure; by default coloured by model confidence (blue = very high, orange = very low, typical of disordered regions).
Granzyme K (GZMK) — Granzyme K — human protein (gene GZMK, 264 amino acids, UniProt P49863). AlphaFold-predicted 3D structure; by default coloured by model confidence (blue = very high, orange = very low, typical of disordered regions).
Matrix metalloproteinase-14 (MMP14) — Matrix metalloproteinase-14 — human protein (gene MMP14, 582 amino acids, UniProt P50281). AlphaFold-predicted 3D structure; by default coloured by model confidence (blue = very high, orange = very low, typical of disordered regions).
Methionine aminopeptidase 2 (METAP2) — Methionine aminopeptidase 2 — human protein (gene METAP2, 478 amino acids, UniProt P50579). AlphaFold-predicted 3D structure; by default coloured by model confidence (blue = very high, orange = very low, typical of disordered regions).
Granzyme M (GZMM) — Granzyme M — human protein (gene GZMM, 257 amino acids, UniProt P51124). AlphaFold-predicted 3D structure; by default coloured by model confidence (blue = very high, orange = very low, typical of disordered regions).
Matrix metalloproteinase-15 (MMP15) — Matrix metalloproteinase-15 — human protein (gene MMP15, 669 amino acids, UniProt P51511). AlphaFold-predicted 3D structure; by default coloured by model confidence (blue = very high, orange = very low, typical of disordered regions).
Matrix metalloproteinase-16 (MMP16) — Matrix metalloproteinase-16 — human protein (gene MMP16, 607 amino acids, UniProt P51512). AlphaFold-predicted 3D structure; by default coloured by model confidence (blue = very high, orange = very low, typical of disordered regions).
Ubiquitin carboxyl-terminal hydrolase 11 (USP11) — Ubiquitin carboxyl-terminal hydrolase 11 — human protein (gene USP11, 963 amino acids, UniProt P51784). AlphaFold-predicted 3D structure; by default coloured by model confidence (blue = very high, orange = very low, typical of disordered regions).
Caspase-5 (CASP5) — Caspase-5 — human protein (gene CASP5, 434 amino acids, UniProt P51878). AlphaFold-predicted 3D structure; by default coloured by model confidence (blue = very high, orange = very low, typical of disordered regions).
Thimet oligopeptidase (THOP1) — Thimet oligopeptidase — human protein (gene THOP1, 689 amino acids, UniProt P52888). AlphaFold-predicted 3D structure; by default coloured by model confidence (blue = very high, orange = very low, typical of disordered regions).
Nuclear pore complex protein Nup98-Nup96 (NUP98) — Nuclear pore complex protein Nup98-Nup96 — human protein (gene NUP98, 1817 amino acids, UniProt P52948). AlphaFold-predicted 3D structure; by default coloured by model confidence (blue = very high, orange = very low, typical of disordered regions).
Methionine aminopeptidase 1 (METAP1) — Methionine aminopeptidase 1 — human protein (gene METAP1, 386 amino acids, UniProt P53582). AlphaFold-predicted 3D structure; by default coloured by model confidence (blue = very high, orange = very low, typical of disordered regions).
Dipeptidyl peptidase 1 (CTSC) — Dipeptidyl peptidase 1 — human protein (gene CTSC, 463 amino acids, UniProt P53634). AlphaFold-predicted 3D structure; by default coloured by model confidence (blue = very high, orange = very low, typical of disordered regions).
Ataxin-3 (ATXN3) — Ataxin-3 — human protein (gene ATXN3, 361 amino acids, UniProt P54252). AlphaFold-predicted 3D structure; by default coloured by model confidence (blue = very high, orange = very low, typical of disordered regions).
Ubiquitin carboxyl-terminal hydrolase 14 (USP14) — Ubiquitin carboxyl-terminal hydrolase 14 — human protein (gene USP14, 494 amino acids, UniProt P54578). AlphaFold-predicted 3D structure; by default coloured by model confidence (blue = very high, orange = very low, typical of disordered regions).
Caspase-7 (CASP7) — Caspase-7 — human protein (gene CASP7, 303 amino acids, UniProt P55210). AlphaFold-predicted 3D structure; by default coloured by model confidence (blue = very high, orange = very low, typical of disordered regions).
Caspase-9 (CASP9) — Caspase-9 — human protein (gene CASP9, 416 amino acids, UniProt P55211). AlphaFold-predicted 3D structure; by default coloured by model confidence (blue = very high, orange = very low, typical of disordered regions).
Caspase-6 (CASP6) — Caspase-6 — human protein (gene CASP6, 293 amino acids, UniProt P55212). AlphaFold-predicted 3D structure; by default coloured by model confidence (blue = very high, orange = very low, typical of disordered regions).
Puromycin-sensitive aminopeptidase (NPEPPS) — Puromycin-sensitive aminopeptidase — human protein (gene NPEPPS, 919 amino acids, UniProt P55786). AlphaFold-predicted 3D structure; by default coloured by model confidence (blue = very high, orange = very low, typical of disordered regions).
Cathepsin W (CTSW) — Cathepsin W — human protein (gene CTSW, 376 amino acids, UniProt P56202). AlphaFold-predicted 3D structure; by default coloured by model confidence (blue = very high, orange = very low, typical of disordered regions).
Neurotrypsin (PRSS12) — Neurotrypsin — human protein (gene PRSS12, 875 amino acids, UniProt P56730). AlphaFold-predicted 3D structure; by default coloured by model confidence (blue = very high, orange = very low, typical of disordered regions).
Beta-secretase 1 (BACE1) — Beta-secretase 1 — human protein (gene BACE1, 501 amino acids, UniProt P56817). AlphaFold-predicted 3D structure; by default coloured by model confidence (blue = very high, orange = very low, typical of disordered regions).
Transmembrane protease serine 3 (TMPRSS3) — Transmembrane protease serine 3 — human protein (gene TMPRSS3, 454 amino acids, UniProt P57727). AlphaFold-predicted 3D structure; by default coloured by model confidence (blue = very high, orange = very low, typical of disordered regions).
A disintegrin and metalloproteinase with thrombospondin motifs 12 (ADAMTS12) — A disintegrin and metalloproteinase with thrombospondin motifs 12 — human protein (gene ADAMTS12, 1594 amino acids, UniProt P58397). AlphaFold-predicted 3D structure; by default coloured by model confidence (blue = very high, orange = very low, typical of disordered regions).
A disintegrin and metalloproteinase with thrombospondin motifs 20 (ADAMTS20) — A disintegrin and metalloproteinase with thrombospondin motifs 20 — human protein (gene ADAMTS20, 1910 amino acids, UniProt P59510). AlphaFold-predicted 3D structure; by default coloured by model confidence (blue = very high, orange = very low, typical of disordered regions).
Ubiquitin carboxyl-terminal hydrolase 46 (USP46) — Ubiquitin carboxyl-terminal hydrolase 46 — human protein (gene USP46, 366 amino acids, UniProt P62068). AlphaFold-predicted 3D structure; by default coloured by model confidence (blue = very high, orange = very low, typical of disordered regions).
Endogenous retrovirus group K member 9 Pol protein (ERVK-9) — Endogenous retrovirus group K member 9 Pol protein — human protein (gene ERVK-9, 1117 amino acids, UniProt P63128). AlphaFold-predicted 3D structure; by default coloured by model confidence (blue = very high, orange = very low, typical of disordered regions).
Signal peptidase complex catalytic subunit SEC11A (SEC11A) — Signal peptidase complex catalytic subunit SEC11A — human protein (gene SEC11A, 179 amino acids, UniProt P67812). AlphaFold-predicted 3D structure; by default coloured by model confidence (blue = very high, orange = very low, typical of disordered regions).
Disintegrin and metalloproteinase domain-containing protein 8 (ADAM8) — Disintegrin and metalloproteinase domain-containing protein 8 — human protein (gene ADAM8, 824 amino acids, UniProt P78325). AlphaFold-predicted 3D structure; by default coloured by model confidence (blue = very high, orange = very low, typical of disordered regions).
Disintegrin and metalloproteinase domain-containing protein 17 (ADAM17) — Disintegrin and metalloproteinase domain-containing protein 17 — human protein (gene ADAM17, 824 amino acids, UniProt P78536). AlphaFold-predicted 3D structure; by default coloured by model confidence (blue = very high, orange = very low, typical of disordered regions).
Phosphate-regulating neutral endopeptidase PHEX (PHEX) — Phosphate-regulating neutral endopeptidase PHEX — human protein (gene PHEX, 749 amino acids, UniProt P78562). AlphaFold-predicted 3D structure; by default coloured by model confidence (blue = very high, orange = very low, typical of disordered regions).
Dermcidin (DCD) — Dermcidin — human protein (gene DCD, 110 amino acids, UniProt P81605). AlphaFold-predicted 3D structure; by default coloured by model confidence (blue = very high, orange = very low, typical of disordered regions).
Serine protease HTRA4 (HTRA4) — Serine protease HTRA4 — human protein (gene HTRA4, 476 amino acids, UniProt P83105). AlphaFold-predicted 3D structure; by default coloured by model confidence (blue = very high, orange = very low, typical of disordered regions).
Serine protease HTRA3 (HTRA3) — Serine protease HTRA3 — human protein (gene HTRA3, 453 amino acids, UniProt P83110). AlphaFold-predicted 3D structure; by default coloured by model confidence (blue = very high, orange = very low, typical of disordered regions).
Serine beta-lactamase-like protein LACTB, mitochondrial (LACTB) — Serine beta-lactamase-like protein LACTB, mitochondrial — human protein (gene LACTB, 547 amino acids, UniProt P83111). AlphaFold-predicted 3D structure; by default coloured by model confidence (blue = very high, orange = very low, typical of disordered regions).
Enteropeptidase (TMPRSS15) — Enteropeptidase — human protein (gene TMPRSS15, 1019 amino acids, UniProt P98073). AlphaFold-predicted 3D structure; by default coloured by model confidence (blue = very high, orange = very low, typical of disordered regions).
OTU domain-containing protein 4 (OTUD4) — OTU domain-containing protein 4 — human protein (gene OTUD4, 1114 amino acids, UniProt Q01804). AlphaFold-predicted 3D structure; by default coloured by model confidence (blue = very high, orange = very low, typical of disordered regions).
Glutamate carboxypeptidase 2 (FOLH1) — Glutamate carboxypeptidase 2 — human protein (gene FOLH1, 750 amino acids, UniProt Q04609). AlphaFold-predicted 3D structure; by default coloured by model confidence (blue = very high, orange = very low, typical of disordered regions).
Hepatocyte growth factor activator serine protease (HGFAC) — Hepatocyte growth factor activator serine protease — human protein (gene HGFAC, 655 amino acids, UniProt Q04756). AlphaFold-predicted 3D structure; by default coloured by model confidence (blue = very high, orange = very low, typical of disordered regions).
Glutamyl aminopeptidase (ENPEP) — Glutamyl aminopeptidase — human protein (gene ENPEP, 957 amino acids, UniProt Q07075). AlphaFold-predicted 3D structure; by default coloured by model confidence (blue = very high, orange = very low, typical of disordered regions).
Ubiquitin carboxyl-terminal hydrolase 17-like protein 24 (USP17L24; USP17L25; USP17L26; USP17L27; USP17L28; USP17L29; USP17L30) — Ubiquitin carboxyl-terminal hydrolase 17-like protein 24 — human protein (gene USP17L24; USP17L25; USP17L26; USP17L27; USP17L28; USP17L29; USP17L30, 530 amino acids, UniProt Q0WX57). AlphaFold-predicted 3D structure; by default coloured by model confidence (blue = very high, orange = very low, typical of disordered regions).
Prolyl endopeptidase FAP (FAP) — Prolyl endopeptidase FAP — human protein (gene FAP, 760 amino acids, UniProt Q12884). AlphaFold-predicted 3D structure; by default coloured by model confidence (blue = very high, orange = very low, typical of disordered regions).
Ubiquitin carboxyl-terminal hydrolase 4 (USP4) — Ubiquitin carboxyl-terminal hydrolase 4 — human protein (gene USP4, 963 amino acids, UniProt Q13107). AlphaFold-predicted 3D structure; by default coloured by model confidence (blue = very high, orange = very low, typical of disordered regions).
Pappalysin-1 (PAPPA) — Pappalysin-1 — human protein (gene PAPPA, 1627 amino acids, UniProt Q13219). AlphaFold-predicted 3D structure; by default coloured by model confidence (blue = very high, orange = very low, typical of disordered regions).
Disintegrin and metalloproteinase domain-containing protein 9 (ADAM9) — Disintegrin and metalloproteinase domain-containing protein 9 — human protein (gene ADAM9, 819 amino acids, UniProt Q13443). AlphaFold-predicted 3D structure; by default coloured by model confidence (blue = very high, orange = very low, typical of disordered regions).
Disintegrin and metalloproteinase domain-containing protein 15 (ADAM15) — Disintegrin and metalloproteinase domain-containing protein 15 — human protein (gene ADAM15, 863 amino acids, UniProt Q13444). AlphaFold-predicted 3D structure; by default coloured by model confidence (blue = very high, orange = very low, typical of disordered regions).
Bleomycin hydrolase (BLMH) — Bleomycin hydrolase — human protein (gene BLMH, 455 amino acids, UniProt Q13867). AlphaFold-predicted 3D structure; by default coloured by model confidence (blue = very high, orange = very low, typical of disordered regions).
Factor VII-activating protease (HABP2) — Factor VII-activating protease — human protein (gene HABP2, 560 amino acids, UniProt Q14520). AlphaFold-predicted 3D structure; by default coloured by model confidence (blue = very high, orange = very low, typical of disordered regions).
Indian hedgehog protein (IHH) — Indian hedgehog protein — human protein (gene IHH, 411 amino acids, UniProt Q14623). AlphaFold-predicted 3D structure; by default coloured by model confidence (blue = very high, orange = very low, typical of disordered regions).
Separin (ESPL1) — Separin — human protein (gene ESPL1, 2120 amino acids, UniProt Q14674). AlphaFold-predicted 3D structure; by default coloured by model confidence (blue = very high, orange = very low, typical of disordered regions).
Ubiquitin carboxyl-terminal hydrolase 10 (USP10) — Ubiquitin carboxyl-terminal hydrolase 10 — human protein (gene USP10, 798 amino acids, UniProt Q14694). AlphaFold-predicted 3D structure; by default coloured by model confidence (blue = very high, orange = very low, typical of disordered regions).
Membrane-bound transcription factor site-1 protease (MBTPS1) — Membrane-bound transcription factor site-1 protease — human protein (gene MBTPS1, 1052 amino acids, UniProt Q14703). AlphaFold-predicted 3D structure; by default coloured by model confidence (blue = very high, orange = very low, typical of disordered regions).
Caspase-8 (CASP8) — Caspase-8 — human protein (gene CASP8, 479 amino acids, UniProt Q14790). AlphaFold-predicted 3D structure; by default coloured by model confidence (blue = very high, orange = very low, typical of disordered regions).
Calcium-activated chloride channel regulator 4 (CLCA4) — Calcium-activated chloride channel regulator 4 — human protein (gene CLCA4, 919 amino acids, UniProt Q14CN2). AlphaFold-predicted 3D structure; by default coloured by model confidence (blue = very high, orange = very low, typical of disordered regions).
Josephin-1 (JOSD1) — Josephin-1 — human protein (gene JOSD1, 202 amino acids, UniProt Q15040). AlphaFold-predicted 3D structure; by default coloured by model confidence (blue = very high, orange = very low, typical of disordered regions).
Sonic hedgehog protein (SHH) — Sonic hedgehog protein — human protein (gene SHH, 462 amino acids, UniProt Q15465). AlphaFold-predicted 3D structure; by default coloured by model confidence (blue = very high, orange = very low, typical of disordered regions).
Tryptase alpha/beta-1 (TPSAB1) — Tryptase alpha/beta-1 — human protein (gene TPSAB1, 275 amino acids, UniProt Q15661). AlphaFold-predicted 3D structure; by default coloured by model confidence (blue = very high, orange = very low, typical of disordered regions).
Proprotein convertase subtilisin/kexin type 7 (PCSK7) — Proprotein convertase subtilisin/kexin type 7 — human protein (gene PCSK7, 785 amino acids, UniProt Q16549). AlphaFold-predicted 3D structure; by default coloured by model confidence (blue = very high, orange = very low, typical of disordered regions).
Prostasin (PRSS8) — Prostasin — human protein (gene PRSS8, 343 amino acids, UniProt Q16651). AlphaFold-predicted 3D structure; by default coloured by model confidence (blue = very high, orange = very low, typical of disordered regions).
ATP-dependent Clp protease proteolytic subunit, mitochondrial (CLPP) — ATP-dependent Clp protease proteolytic subunit, mitochondrial — human protein (gene CLPP, 277 amino acids, UniProt Q16740). AlphaFold-predicted 3D structure; by default coloured by model confidence (blue = very high, orange = very low, typical of disordered regions).
Meprin A subunit alpha (MEP1A) — Meprin A subunit alpha — human protein (gene MEP1A, 746 amino acids, UniProt Q16819). AlphaFold-predicted 3D structure; by default coloured by model confidence (blue = very high, orange = very low, typical of disordered regions).
Meprin A subunit beta (MEP1B) — Meprin A subunit beta — human protein (gene MEP1B, 701 amino acids, UniProt Q16820). AlphaFold-predicted 3D structure; by default coloured by model confidence (blue = very high, orange = very low, typical of disordered regions).
Peroxisomal leader peptide-processing protease (TYSND1) — Peroxisomal leader peptide-processing protease — human protein (gene TYSND1, 566 amino acids, UniProt Q2T9J0). AlphaFold-predicted 3D structure; by default coloured by model confidence (blue = very high, orange = very low, typical of disordered regions).
Membrane metallo-endopeptidase-like 1 (MMEL1) — Membrane metallo-endopeptidase-like 1 — human protein (gene MMEL1, 779 amino acids, UniProt Q495T6). AlphaFold-predicted 3D structure; by default coloured by model confidence (blue = very high, orange = very low, typical of disordered regions).
Prolyl endopeptidase-like (PREPL) — Prolyl endopeptidase-like — human protein (gene PREPL, 727 amino acids, UniProt Q4J6C6). AlphaFold-predicted 3D structure; by default coloured by model confidence (blue = very high, orange = very low, typical of disordered regions).
Retroviral-like aspartic protease 1 (ASPRV1) — Retroviral-like aspartic protease 1 — human protein (gene ASPRV1, 343 amino acids, UniProt Q53RT3). AlphaFold-predicted 3D structure; by default coloured by model confidence (blue = very high, orange = very low, typical of disordered regions).
Actin maturation protease (ACTMAP) — Actin maturation protease — human protein (gene ACTMAP, 351 amino acids, UniProt Q5BKX5). AlphaFold-predicted 3D structure; by default coloured by model confidence (blue = very high, orange = very low, typical of disordered regions).
Presequence protease, mitochondrial (PITRM1) — Presequence protease, mitochondrial — human protein (gene PITRM1, 1037 amino acids, UniProt Q5JRX3). AlphaFold-predicted 3D structure; by default coloured by model confidence (blue = very high, orange = very low, typical of disordered regions).
Polyserase-2 (PRSS36) — Polyserase-2 — human protein (gene PRSS36, 855 amino acids, UniProt Q5K4E3). AlphaFold-predicted 3D structure; by default coloured by model confidence (blue = very high, orange = very low, typical of disordered regions).
OTU domain-containing protein 3 (OTUD3) — OTU domain-containing protein 3 — human protein (gene OTUD3, 398 amino acids, UniProt Q5T2D3). AlphaFold-predicted 3D structure; by default coloured by model confidence (blue = very high, orange = very low, typical of disordered regions).
Protein DDI1 homolog 2 (DDI2) — Protein DDI1 homolog 2 — human protein (gene DDI2, 399 amino acids, UniProt Q5TDH0). AlphaFold-predicted 3D structure; by default coloured by model confidence (blue = very high, orange = very low, typical of disordered regions).
Cytosolic carboxypeptidase 2 (AGBL2) — Cytosolic carboxypeptidase 2 — human protein (gene AGBL2, 902 amino acids, UniProt Q5U5Z8). AlphaFold-predicted 3D structure; by default coloured by model confidence (blue = very high, orange = very low, typical of disordered regions).
Cytosolic carboxypeptidase 6 (AGBL4) — Cytosolic carboxypeptidase 6 — human protein (gene AGBL4, 503 amino acids, UniProt Q5VU57). AlphaFold-predicted 3D structure; by default coloured by model confidence (blue = very high, orange = very low, typical of disordered regions).
Deubiquitinase MYSM1 (MYSM1) — Deubiquitinase MYSM1 — human protein (gene MYSM1, 828 amino acids, UniProt Q5VVJ2). AlphaFold-predicted 3D structure; by default coloured by model confidence (blue = very high, orange = very low, typical of disordered regions).
Ubiquitin thioesterase OTU1 (YOD1) — Ubiquitin thioesterase OTU1 — human protein (gene YOD1, 348 amino acids, UniProt Q5VVQ6). AlphaFold-predicted 3D structure; by default coloured by model confidence (blue = very high, orange = very low, typical of disordered regions).
SUMO-specific isopeptidase USPL1 (USPL1) — SUMO-specific isopeptidase USPL1 — human protein (gene USPL1, 1092 amino acids, UniProt Q5W0Q7). AlphaFold-predicted 3D structure; by default coloured by model confidence (blue = very high, orange = very low, typical of disordered regions).
Carboxypeptidase Z (CPZ) — Carboxypeptidase Z — human protein (gene CPZ, 652 amino acids, UniProt Q66K79). AlphaFold-predicted 3D structure; by default coloured by model confidence (blue = very high, orange = very low, typical of disordered regions).
Microtubule-associated tyrosine carboxypeptidase 1 (MATCAP1) — Microtubule-associated tyrosine carboxypeptidase 1 — human protein (gene MATCAP1, 471 amino acids, UniProt Q68EN5). AlphaFold-predicted 3D structure; by default coloured by model confidence (blue = very high, orange = very low, typical of disordered regions).
OTU domain-containing protein 7B (OTUD7B) — OTU domain-containing protein 7B — human protein (gene OTUD7B, 843 amino acids, UniProt Q6GQQ9). AlphaFold-predicted 3D structure; by default coloured by model confidence (blue = very high, orange = very low, typical of disordered regions).
N-fatty-acyl-amino acid synthase/hydrolase PM20D1 (PM20D1) — N-fatty-acyl-amino acid synthase/hydrolase PM20D1 — human protein (gene PM20D1, 502 amino acids, UniProt Q6GTS8). AlphaFold-predicted 3D structure; by default coloured by model confidence (blue = very high, orange = very low, typical of disordered regions).
Astacin-like metalloendopeptidase (ASTL) — Astacin-like metalloendopeptidase — human protein (gene ASTL, 431 amino acids, UniProt Q6HA08). AlphaFold-predicted 3D structure; by default coloured by model confidence (blue = very high, orange = very low, typical of disordered regions).
Desumoylating isopeptidase 1 (DESI1) — Desumoylating isopeptidase 1 — human protein (gene DESI1, 168 amino acids, UniProt Q6ICB0). AlphaFold-predicted 3D structure; by default coloured by model confidence (blue = very high, orange = very low, typical of disordered regions).
Ufm1-specific protease 1 (UFSP1) — Ufm1-specific protease 1 — human protein (gene UFSP1, 218 amino acids, UniProt Q6NVU6). AlphaFold-predicted 3D structure; by default coloured by model confidence (blue = very high, orange = very low, typical of disordered regions).
Endoplasmic reticulum aminopeptidase 2 (ERAP2) — Endoplasmic reticulum aminopeptidase 2 — human protein (gene ERAP2, 960 amino acids, UniProt Q6P179). AlphaFold-predicted 3D structure; by default coloured by model confidence (blue = very high, orange = very low, typical of disordered regions).
Lysosomal leucine aminopeptidase (PLBD1) — Lysosomal leucine aminopeptidase — human protein (gene PLBD1, 553 amino acids, UniProt Q6P4A8). AlphaFold-predicted 3D structure; by default coloured by model confidence (blue = very high, orange = very low, typical of disordered regions).
Aminopeptidase Q (LVRN) — Aminopeptidase Q — human protein (gene LVRN, 990 amino acids, UniProt Q6Q4G3). AlphaFold-predicted 3D structure; by default coloured by model confidence (blue = very high, orange = very low, typical of disordered regions).
Ubiquitin carboxyl-terminal hydrolase 17-like protein 6 (USP17L6P) — Ubiquitin carboxyl-terminal hydrolase 17-like protein 6 — human protein (gene USP17L6P, 398 amino acids, UniProt Q6QN14). AlphaFold-predicted 3D structure; by default coloured by model confidence (blue = very high, orange = very low, typical of disordered regions).
Ubiquitin carboxyl-terminal hydrolase 17 (USP17L2) — Ubiquitin carboxyl-terminal hydrolase 17 — human protein (gene USP17L2, 530 amino acids, UniProt Q6R6M4). AlphaFold-predicted 3D structure; by default coloured by model confidence (blue = very high, orange = very low, typical of disordered regions).
Serine protease FAM111B (FAM111B) — Serine protease FAM111B — human protein (gene FAM111B, 734 amino acids, UniProt Q6SJ93). AlphaFold-predicted 3D structure; by default coloured by model confidence (blue = very high, orange = very low, typical of disordered regions).
Methionine aminopeptidase 1D, mitochondrial (METAP1D) — Methionine aminopeptidase 1D, mitochondrial — human protein (gene METAP1D, 335 amino acids, UniProt Q6UB28). AlphaFold-predicted 3D structure; by default coloured by model confidence (blue = very high, orange = very low, typical of disordered regions).
Proprotein convertase subtilisin/kexin type 4 (PCSK4) — Proprotein convertase subtilisin/kexin type 4 — human protein (gene PCSK4, 755 amino acids, UniProt Q6UW60). AlphaFold-predicted 3D structure; by default coloured by model confidence (blue = very high, orange = very low, typical of disordered regions).
Serine protease 55 (PRSS55) — Serine protease 55 — human protein (gene PRSS55, 352 amino acids, UniProt Q6UWB4). AlphaFold-predicted 3D structure; by default coloured by model confidence (blue = very high, orange = very low, typical of disordered regions).
Serine protease 57 (PRSS57) — Serine protease 57 — human protein (gene PRSS57, 283 amino acids, UniProt Q6UWY2). AlphaFold-predicted 3D structure; by default coloured by model confidence (blue = very high, orange = very low, typical of disordered regions).
Dipeptidyl peptidase 8 (DPP8) — Dipeptidyl peptidase 8 — human protein (gene DPP8, 898 amino acids, UniProt Q6V1X1). AlphaFold-predicted 3D structure; by default coloured by model confidence (blue = very high, orange = very low, typical of disordered regions).