Library › DNA & Proteins › Human proteins (AlphaFold) · Senescence & SASP

Human proteins (AlphaFold) · Senescence & SASP: 55 3D models

DNA, RNA, nucleic-acid drugs, gene editing, proteins and 300+ real PDB structures (real sizes 1–100 nm). Each one is a ready-made 3D model you can turn, recolour and place in a figure — open BioDiorama and type its name in the Library search.

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Prelamin-A/C (LMNA) — Prelamin-A/C — human protein (gene LMNA, 664 amino acids, UniProt P02545). AlphaFold-predicted 3D structure; by default coloured by model confidence (blue = very high, orange = very low, typical of disordered regions).
Plasminogen activator inhibitor 1 (SERPINE1) — Plasminogen activator inhibitor 1 — human protein (gene SERPINE1, 402 amino acids, UniProt P05121). AlphaFold-predicted 3D structure; by default coloured by model confidence (blue = very high, orange = very low, typical of disordered regions).
Lamin-B2 (LMNB2) — Lamin-B2 — human protein (gene LMNB2, 620 amino acids, UniProt Q03252). AlphaFold-predicted 3D structure; by default coloured by model confidence (blue = very high, orange = very low, typical of disordered regions).
C-C motif chemokine 26 (CCL26) — C-C motif chemokine 26 — human protein (gene CCL26, 94 amino acids, UniProt Q9Y258). AlphaFold-predicted 3D structure; by default coloured by model confidence (blue = very high, orange = very low, typical of disordered regions).
Telomerase reverse transcriptase (TERT) — Telomerase reverse transcriptase — human protein (gene TERT, 1132 amino acids, UniProt O14746). AlphaFold-predicted 3D structure; by default coloured by model confidence (blue = very high, orange = very low, typical of disordered regions).
Metalloproteinase inhibitor 2 (TIMP2) — Metalloproteinase inhibitor 2 — human protein (gene TIMP2, 220 amino acids, UniProt P16035). AlphaFold-predicted 3D structure; by default coloured by model confidence (blue = very high, orange = very low, typical of disordered regions).
Insulin-like growth factor-binding protein 2 (IGFBP2) — Insulin-like growth factor-binding protein 2 — human protein (gene IGFBP2, 325 amino acids, UniProt P18065). AlphaFold-predicted 3D structure; by default coloured by model confidence (blue = very high, orange = very low, typical of disordered regions).
Alpha-1-antitrypsin-related protein (SERPINA2) — Alpha-1-antitrypsin-related protein — human protein (gene SERPINA2, 421 amino acids, UniProt P20848). AlphaFold-predicted 3D structure; by default coloured by model confidence (blue = very high, orange = very low, typical of disordered regions).
Insulin-like growth factor-binding protein 4 (IGFBP4) — Insulin-like growth factor-binding protein 4 — human protein (gene IGFBP4, 258 amino acids, UniProt P22692). AlphaFold-predicted 3D structure; by default coloured by model confidence (blue = very high, orange = very low, typical of disordered regions).
Insulin-like growth factor-binding protein 6 (IGFBP6) — Insulin-like growth factor-binding protein 6 — human protein (gene IGFBP6, 240 amino acids, UniProt P24592). AlphaFold-predicted 3D structure; by default coloured by model confidence (blue = very high, orange = very low, typical of disordered regions).
Insulin-like growth factor-binding protein 5 (IGFBP5) — Insulin-like growth factor-binding protein 5 — human protein (gene IGFBP5, 272 amino acids, UniProt P24593). AlphaFold-predicted 3D structure; by default coloured by model confidence (blue = very high, orange = very low, typical of disordered regions).
Telomeric repeat-binding factor 1 (TERF1) — Telomeric repeat-binding factor 1 — human protein (gene TERF1, 439 amino acids, UniProt P54274). AlphaFold-predicted 3D structure; by default coloured by model confidence (blue = very high, orange = very low, typical of disordered regions).
Telomeric repeat-binding factor 2 (TERF2) — Telomeric repeat-binding factor 2 — human protein (gene TERF2, 542 amino acids, UniProt Q15554). AlphaFold-predicted 3D structure; by default coloured by model confidence (blue = very high, orange = very low, typical of disordered regions).
Bcl-2-like protein 2 (BCL2L2) — Bcl-2-like protein 2 — human protein (gene BCL2L2, 193 amino acids, UniProt Q92843). AlphaFold-predicted 3D structure; by default coloured by model confidence (blue = very high, orange = very low, typical of disordered regions).
TERF1-interacting nuclear factor 2 (TINF2) — TERF1-interacting nuclear factor 2 — human protein (gene TINF2, 451 amino acids, UniProt Q9BSI4). AlphaFold-predicted 3D structure; by default coloured by model confidence (blue = very high, orange = very low, typical of disordered regions).
Anthrax toxin receptor 1 (ANTXR1) — Anthrax toxin receptor 1 — human protein (gene ANTXR1, 564 amino acids, UniProt Q9H6X2). AlphaFold-predicted 3D structure; by default coloured by model confidence (blue = very high, orange = very low, typical of disordered regions).
Protection of telomeres protein 1 (POT1) — Protection of telomeres protein 1 — human protein (gene POT1, 634 amino acids, UniProt Q9NUX5). AlphaFold-predicted 3D structure; by default coloured by model confidence (blue = very high, orange = very low, typical of disordered regions).
Telomeric repeat-binding factor 2-interacting protein 1 (TERF2IP) — Telomeric repeat-binding factor 2-interacting protein 1 — human protein (gene TERF2IP, 399 amino acids, UniProt Q9NYB0). AlphaFold-predicted 3D structure; by default coloured by model confidence (blue = very high, orange = very low, typical of disordered regions).
Protein Mdm4 (MDM4) — Protein Mdm4 — human protein (gene MDM4, 490 amino acids, UniProt O15151). AlphaFold-predicted 3D structure; by default coloured by model confidence (blue = very high, orange = very low, typical of disordered regions).
Nuclear pore glycoprotein p62 (NUP62) — Nuclear pore glycoprotein p62 — human protein (gene NUP62, 522 amino acids, UniProt P37198). AlphaFold-predicted 3D structure; by default coloured by model confidence (blue = very high, orange = very low, typical of disordered regions).
Signal transducer and activator of transcription 3 (STAT3) — Signal transducer and activator of transcription 3 — human protein (gene STAT3, 770 amino acids, UniProt P40763). AlphaFold-predicted 3D structure; by default coloured by model confidence (blue = very high, orange = very low, typical of disordered regions).
Transcription factor GATA-4 (GATA4) — Transcription factor GATA-4 — human protein (gene GATA4, 442 amino acids, UniProt P43694). AlphaFold-predicted 3D structure; by default coloured by model confidence (blue = very high, orange = very low, typical of disordered regions).
Nuclear pore complex protein Nup153 (NUP153) — Nuclear pore complex protein Nup153 — human protein (gene NUP153, 1475 amino acids, UniProt P49790). AlphaFold-predicted 3D structure; by default coloured by model confidence (blue = very high, orange = very low, typical of disordered regions).
Regulatory-associated protein of mTOR (RPTOR) — Regulatory-associated protein of mTOR — human protein (gene RPTOR, 1335 amino acids, UniProt Q8N122). AlphaFold-predicted 3D structure; by default coloured by model confidence (blue = very high, orange = very low, typical of disordered regions).
Nuclear pore complex protein Nup93 (NUP93) — Nuclear pore complex protein Nup93 — human protein (gene NUP93, 819 amino acids, UniProt Q8N1F7). AlphaFold-predicted 3D structure; by default coloured by model confidence (blue = very high, orange = very low, typical of disordered regions).
Zinc finger matrin-type protein 3 (ZMAT3) — Zinc finger matrin-type protein 3 — human protein (gene ZMAT3, 289 amino acids, UniProt Q9HA38). AlphaFold-predicted 3D structure; by default coloured by model confidence (blue = very high, orange = very low, typical of disordered regions).
Sentrin-specific protease 1 (SENP1) — Sentrin-specific protease 1 — human protein (gene SENP1, 644 amino acids, UniProt Q9P0U3). AlphaFold-predicted 3D structure; by default coloured by model confidence (blue = very high, orange = very low, typical of disordered regions).
Histone chaperone ASF1A (ASF1A) — Histone chaperone ASF1A — human protein (gene ASF1A, 204 amino acids, UniProt Q9Y294). AlphaFold-predicted 3D structure; by default coloured by model confidence (blue = very high, orange = very low, typical of disordered regions).
Calcineurin-binding protein cabin-1 (CABIN1) — Calcineurin-binding protein cabin-1 — human protein (gene CABIN1, 2220 amino acids, UniProt Q9Y6J0). AlphaFold-predicted 3D structure; by default coloured by model confidence (blue = very high, orange = very low, typical of disordered regions).
Eukaryotic translation elongation factor 1 epsilon-1 (EEF1E1) — Eukaryotic translation elongation factor 1 epsilon-1 — human protein (gene EEF1E1, 174 amino acids, UniProt O43324). AlphaFold-predicted 3D structure; by default coloured by model confidence (blue = very high, orange = very low, typical of disordered regions).
Ribosomal L1 domain-containing protein 1 (RSL1D1) — Ribosomal L1 domain-containing protein 1 — human protein (gene RSL1D1, 490 amino acids, UniProt O76021). AlphaFold-predicted 3D structure; by default coloured by model confidence (blue = very high, orange = very low, typical of disordered regions).
Cyclin-A2 (CCNA2) — Cyclin-A2 — human protein (gene CCNA2, 432 amino acids, UniProt P20248). AlphaFold-predicted 3D structure; by default coloured by model confidence (blue = very high, orange = very low, typical of disordered regions).
Beta-2-microglobulin (B2M) — Beta-2-microglobulin — human protein (gene B2M, 119 amino acids, UniProt P61769). AlphaFold-predicted 3D structure; by default coloured by model confidence (blue = very high, orange = very low, typical of disordered regions).
DNA topoisomerase 2-beta (TOP2B) — DNA topoisomerase 2-beta — human protein (gene TOP2B, 1626 amino acids, UniProt Q02880). AlphaFold-predicted 3D structure; by default coloured by model confidence (blue = very high, orange = very low, typical of disordered regions).
Secretory phospholipase A2 receptor (PLA2R1) — Secretory phospholipase A2 receptor — human protein (gene PLA2R1, 1463 amino acids, UniProt Q13018). AlphaFold-predicted 3D structure; by default coloured by model confidence (blue = very high, orange = very low, typical of disordered regions).
Mitogen-activated protein kinase 11 (MAPK11) — Mitogen-activated protein kinase 11 — human protein (gene MAPK11, 364 amino acids, UniProt Q15759). AlphaFold-predicted 3D structure; by default coloured by model confidence (blue = very high, orange = very low, typical of disordered regions).
Tubulinyl-Tyr carboxypeptidase 1 (VASH1) — Tubulinyl-Tyr carboxypeptidase 1 — human protein (gene VASH1, 365 amino acids, UniProt Q7L8A9). AlphaFold-predicted 3D structure; by default coloured by model confidence (blue = very high, orange = very low, typical of disordered regions).
Polyribonucleotide nucleotidyltransferase 1, mitochondrial (PNPT1) — Polyribonucleotide nucleotidyltransferase 1, mitochondrial — human protein (gene PNPT1, 783 amino acids, UniProt Q8TCS8). AlphaFold-predicted 3D structure; by default coloured by model confidence (blue = very high, orange = very low, typical of disordered regions).
PRKC apoptosis WT1 regulator protein (PAWR) — PRKC apoptosis WT1 regulator protein — human protein (gene PAWR, 340 amino acids, UniProt Q96IZ0). AlphaFold-predicted 3D structure; by default coloured by model confidence (blue = very high, orange = very low, typical of disordered regions).
E3 SUMO-protein ligase NSE2 (NSMCE2) — E3 SUMO-protein ligase NSE2 — human protein (gene NSMCE2, 247 amino acids, UniProt Q96MF7). AlphaFold-predicted 3D structure; by default coloured by model confidence (blue = very high, orange = very low, typical of disordered regions).
Structural maintenance of chromosomes protein 6 (SMC6) — Structural maintenance of chromosomes protein 6 — human protein (gene SMC6, 1091 amino acids, UniProt Q96SB8). AlphaFold-predicted 3D structure; by default coloured by model confidence (blue = very high, orange = very low, typical of disordered regions).
Mitogen-activated protein kinase kinase kinase 5 (MAP3K5) — Mitogen-activated protein kinase kinase kinase 5 — human protein (gene MAP3K5, 1374 amino acids, UniProt Q99683). AlphaFold-predicted 3D structure; by default coloured by model confidence (blue = very high, orange = very low, typical of disordered regions).
Killer cell immunoglobulin-like receptor 2DL4 (KIR2DL4) — Killer cell immunoglobulin-like receptor 2DL4 — human protein (gene KIR2DL4, 377 amino acids, UniProt Q99706). AlphaFold-predicted 3D structure; by default coloured by model confidence (blue = very high, orange = very low, typical of disordered regions).
Sphingosine-1-phosphate phosphatase 1 (SGPP1) — Sphingosine-1-phosphate phosphatase 1 — human protein (gene SGPP1, 441 amino acids, UniProt Q9BX95). AlphaFold-predicted 3D structure; by default coloured by model confidence (blue = very high, orange = very low, typical of disordered regions).
Serine/threonine-protein kinase Nek6 (NEK6) — Serine/threonine-protein kinase Nek6 — human protein (gene NEK6, 313 amino acids, UniProt Q9HC98). AlphaFold-predicted 3D structure; by default coloured by model confidence (blue = very high, orange = very low, typical of disordered regions).
ABI gene family member 3 (ABI3) — ABI gene family member 3 — human protein (gene ABI3, 366 amino acids, UniProt Q9P2A4). AlphaFold-predicted 3D structure; by default coloured by model confidence (blue = very high, orange = very low, typical of disordered regions).
Tumor necrosis factor receptor superfamily member 10D (TNFRSF10D) — Tumor necrosis factor receptor superfamily member 10D — human protein (gene TNFRSF10D, 386 amino acids, UniProt Q9UBN6). AlphaFold-predicted 3D structure; by default coloured by model confidence (blue = very high, orange = very low, typical of disordered regions).
F-box only protein 5 (FBXO5) — F-box only protein 5 — human protein (gene FBXO5, 447 amino acids, UniProt Q9UKT4). AlphaFold-predicted 3D structure; by default coloured by model confidence (blue = very high, orange = very low, typical of disordered regions).
RAC-gamma serine/threonine-protein kinase (AKT3) — RAC-gamma serine/threonine-protein kinase — human protein (gene AKT3, 479 amino acids, UniProt Q9Y243). AlphaFold-predicted 3D structure; by default coloured by model confidence (blue = very high, orange = very low, typical of disordered regions).
C-X-C motif chemokine 3 (CXCL3) — C-X-C motif chemokine 3 — human protein (gene CXCL3, 107 amino acids, UniProt P19876). AlphaFold-predicted 3D structure; by default coloured by model confidence (blue = very high, orange = very low, typical of disordered regions).
Augurin (ECRG4) — Augurin — human protein (gene ECRG4, 148 amino acids, UniProt Q9H1Z8). AlphaFold-predicted 3D structure; by default coloured by model confidence (blue = very high, orange = very low, typical of disordered regions).
Protein yippee-like 3 (YPEL3) — Protein yippee-like 3 — human protein (gene YPEL3, 119 amino acids, UniProt P61236). AlphaFold-predicted 3D structure; by default coloured by model confidence (blue = very high, orange = very low, typical of disordered regions).
Beta-galactosidase (GLB1) — Beta-galactosidase — human protein (gene GLB1, 677 amino acids, UniProt P16278). AlphaFold-predicted 3D structure; by default coloured by model confidence (blue = very high, orange = very low, typical of disordered regions).
Lamin-B1 (LMNB1) — Lamin-B1 — human protein (gene LMNB1, 586 amino acids, UniProt P20700). AlphaFold-predicted 3D structure; by default coloured by model confidence (blue = very high, orange = very low, typical of disordered regions).
Cyclin-dependent kinase 4 inhibitor C (CDKN2C) — Cyclin-dependent kinase 4 inhibitor C — human protein (gene CDKN2C, 168 amino acids, UniProt P42773). AlphaFold-predicted 3D structure; by default coloured by model confidence (blue = very high, orange = very low, typical of disordered regions).