Library › DNA & Proteins › Human proteins (AlphaFold) · Synapse & neurodegeneration

Human proteins (AlphaFold) · Synapse & neurodegeneration: 55 3D models

DNA, RNA, nucleic-acid drugs, gene editing, proteins and 300+ real PDB structures (real sizes 1–100 nm). Each one is a ready-made 3D model you can turn, recolour and place in a figure — open BioDiorama and type its name in the Library search.

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Synaptosomal-associated protein 23 (SNAP23) — Synaptosomal-associated protein 23 — human protein (gene SNAP23, 211 amino acids, UniProt O00161). AlphaFold-predicted 3D structure; by default coloured by model confidence (blue = very high, orange = very low, typical of disordered regions).
Syntaxin-7 (STX7) — Syntaxin-7 — human protein (gene STX7, 261 amino acids, UniProt O15400). AlphaFold-predicted 3D structure; by default coloured by model confidence (blue = very high, orange = very low, typical of disordered regions).
Vesicle-associated membrane protein 4 (VAMP4) — Vesicle-associated membrane protein 4 — human protein (gene VAMP4, 141 amino acids, UniProt O75379). AlphaFold-predicted 3D structure; by default coloured by model confidence (blue = very high, orange = very low, typical of disordered regions).
Syntaxin-2 (STX2) — Syntaxin-2 — human protein (gene STX2, 288 amino acids, UniProt P32856). AlphaFold-predicted 3D structure; by default coloured by model confidence (blue = very high, orange = very low, typical of disordered regions).
Syntaxin-binding protein 1 (STXBP1) — Syntaxin-binding protein 1 — human protein (gene STXBP1, 594 amino acids, UniProt P61764). AlphaFold-predicted 3D structure; by default coloured by model confidence (blue = very high, orange = very low, typical of disordered regions).
Syntaxin-5 (STX5) — Syntaxin-5 — human protein (gene STX5, 355 amino acids, UniProt Q13190). AlphaFold-predicted 3D structure; by default coloured by model confidence (blue = very high, orange = very low, typical of disordered regions).
Syntaxin-3 (STX3) — Syntaxin-3 — human protein (gene STX3, 289 amino acids, UniProt Q13277). AlphaFold-predicted 3D structure; by default coloured by model confidence (blue = very high, orange = very low, typical of disordered regions).
Double C2-like domain-containing protein beta (DOC2B) — Double C2-like domain-containing protein beta — human protein (gene DOC2B, 412 amino acids, UniProt Q14184). AlphaFold-predicted 3D structure; by default coloured by model confidence (blue = very high, orange = very low, typical of disordered regions).
Syntaxin-binding protein 2 (STXBP2) — Syntaxin-binding protein 2 — human protein (gene STXBP2, 593 amino acids, UniProt Q15833). AlphaFold-predicted 3D structure; by default coloured by model confidence (blue = very high, orange = very low, typical of disordered regions).
Synaptotagmin-16 (SYT16) — Synaptotagmin-16 — human protein (gene SYT16, 645 amino acids, UniProt Q17RD7). AlphaFold-predicted 3D structure; by default coloured by model confidence (blue = very high, orange = very low, typical of disordered regions).
Synaptotagmin-10 (SYT10) — Synaptotagmin-10 — human protein (gene SYT10, 523 amino acids, UniProt Q6XYQ8). AlphaFold-predicted 3D structure; by default coloured by model confidence (blue = very high, orange = very low, typical of disordered regions).
Synaptotagmin-14 (SYT14) — Synaptotagmin-14 — human protein (gene SYT14, 555 amino acids, UniProt Q8NB59). AlphaFold-predicted 3D structure; by default coloured by model confidence (blue = very high, orange = very low, typical of disordered regions).
Synaptotagmin-3 (SYT3) — Synaptotagmin-3 — human protein (gene SYT3, 590 amino acids, UniProt Q9BQG1). AlphaFold-predicted 3D structure; by default coloured by model confidence (blue = very high, orange = very low, typical of disordered regions).
Synaptotagmin-15 (SYT15) — Synaptotagmin-15 — human protein (gene SYT15, 421 amino acids, UniProt Q9BQS2). AlphaFold-predicted 3D structure; by default coloured by model confidence (blue = very high, orange = very low, typical of disordered regions).
Synaptotagmin-17 (SYT17) — Synaptotagmin-17 — human protein (gene SYT17, 474 amino acids, UniProt Q9BSW7). AlphaFold-predicted 3D structure; by default coloured by model confidence (blue = very high, orange = very low, typical of disordered regions).
Synaptotagmin-11 (SYT11) — Synaptotagmin-11 — human protein (gene SYT11, 431 amino acids, UniProt Q9BT88). AlphaFold-predicted 3D structure; by default coloured by model confidence (blue = very high, orange = very low, typical of disordered regions).
Synaptotagmin-4 (SYT4) — Synaptotagmin-4 — human protein (gene SYT4, 425 amino acids, UniProt Q9H2B2). AlphaFold-predicted 3D structure; by default coloured by model confidence (blue = very high, orange = very low, typical of disordered regions).
Syntaxin-binding protein 3 (STXBP3) — Syntaxin-binding protein 3 — human protein (gene STXBP3, 592 amino acids, UniProt O00186). AlphaFold-predicted 3D structure; by default coloured by model confidence (blue = very high, orange = very low, typical of disordered regions).
Kappa-casein (CSN3) — Kappa-casein — human protein (gene CSN3, 182 amino acids, UniProt P07498). AlphaFold-predicted 3D structure; by default coloured by model confidence (blue = very high, orange = very low, typical of disordered regions).
Vesicle-fusing ATPase (NSF) — Vesicle-fusing ATPase — human protein (gene NSF, 744 amino acids, UniProt P46459). AlphaFold-predicted 3D structure; by default coloured by model confidence (blue = very high, orange = very low, typical of disordered regions).
Alpha-soluble NSF attachment protein (NAPA) — Alpha-soluble NSF attachment protein — human protein (gene NAPA, 295 amino acids, UniProt P54920). AlphaFold-predicted 3D structure; by default coloured by model confidence (blue = very high, orange = very low, typical of disordered regions).
Amyloid-beta A4 precursor protein-binding family A member 1 (APBA1) — Amyloid-beta A4 precursor protein-binding family A member 1 — human protein (gene APBA1, 837 amino acids, UniProt Q02410). AlphaFold-predicted 3D structure; by default coloured by model confidence (blue = very high, orange = very low, typical of disordered regions).
MAGUK p55 subfamily member 3 (MPP3) — MAGUK p55 subfamily member 3 — human protein (gene MPP3, 585 amino acids, UniProt Q13368). AlphaFold-predicted 3D structure; by default coloured by model confidence (blue = very high, orange = very low, typical of disordered regions).
Synaptophysin-like protein 1 (SYPL1) — Synaptophysin-like protein 1 — human protein (gene SYPL1, 259 amino acids, UniProt Q16563). AlphaFold-predicted 3D structure; by default coloured by model confidence (blue = very high, orange = very low, typical of disordered regions).
Gamma-soluble NSF attachment protein (NAPG) — Gamma-soluble NSF attachment protein — human protein (gene NAPG, 312 amino acids, UniProt Q99747). AlphaFold-predicted 3D structure; by default coloured by model confidence (blue = very high, orange = very low, typical of disordered regions).
Beta-soluble NSF attachment protein (NAPB) — Beta-soluble NSF attachment protein — human protein (gene NAPB, 298 amino acids, UniProt Q9H115). AlphaFold-predicted 3D structure; by default coloured by model confidence (blue = very high, orange = very low, typical of disordered regions).
Regulating synaptic membrane exocytosis protein 3 (RIMS3) — Regulating synaptic membrane exocytosis protein 3 — human protein (gene RIMS3, 308 amino acids, UniProt Q9UJD0). AlphaFold-predicted 3D structure; by default coloured by model confidence (blue = very high, orange = very low, typical of disordered regions).
Regulating synaptic membrane exocytosis protein 2 (RIMS2) — Regulating synaptic membrane exocytosis protein 2 — human protein (gene RIMS2, 1411 amino acids, UniProt Q9UQ26). AlphaFold-predicted 3D structure; by default coloured by model confidence (blue = very high, orange = very low, typical of disordered regions).
SH3 and multiple ankyrin repeat domains protein 1 (SHANK1) — SH3 and multiple ankyrin repeat domains protein 1 — human protein (gene SHANK1, 2161 amino acids, UniProt Q9Y566). AlphaFold-predicted 3D structure; by default coloured by model confidence (blue = very high, orange = very low, typical of disordered regions).
Leucine-rich repeat-containing protein 4B (LRRC4B) — Leucine-rich repeat-containing protein 4B — human protein (gene LRRC4B, 713 amino acids, UniProt Q9NT99). AlphaFold-predicted 3D structure; by default coloured by model confidence (blue = very high, orange = very low, typical of disordered regions).
SH3 and multiple ankyrin repeat domains protein 3 (SHANK3) — SH3 and multiple ankyrin repeat domains protein 3 — human protein (gene SHANK3, 1806 amino acids, UniProt Q9BYB0). AlphaFold-predicted 3D structure; by default coloured by model confidence (blue = very high, orange = very low, typical of disordered regions).
SLIT and NTRK-like protein 1 (SLITRK1) — SLIT and NTRK-like protein 1 — human protein (gene SLITRK1, 696 amino acids, UniProt Q96PX8). AlphaFold-predicted 3D structure; by default coloured by model confidence (blue = very high, orange = very low, typical of disordered regions).
Leucine-rich repeat-containing protein 4 (LRRC4) — Leucine-rich repeat-containing protein 4 — human protein (gene LRRC4, 653 amino acids, UniProt Q9HBW1). AlphaFold-predicted 3D structure; by default coloured by model confidence (blue = very high, orange = very low, typical of disordered regions).
Contactin-associated protein-like 2 (CNTNAP2) — Contactin-associated protein-like 2 — human protein (gene CNTNAP2, 1331 amino acids, UniProt Q9UHC6). AlphaFold-predicted 3D structure; by default coloured by model confidence (blue = very high, orange = very low, typical of disordered regions).
Disks large-associated protein 2 (DLGAP2) — Disks large-associated protein 2 — human protein (gene DLGAP2, 1054 amino acids, UniProt Q9P1A6). AlphaFold-predicted 3D structure; by default coloured by model confidence (blue = very high, orange = very low, typical of disordered regions).
Ras/Rap GTPase-activating protein SynGAP (SYNGAP1) — Ras/Rap GTPase-activating protein SynGAP — human protein (gene SYNGAP1, 1343 amino acids, UniProt Q96PV0). AlphaFold-predicted 3D structure; by default coloured by model confidence (blue = very high, orange = very low, typical of disordered regions).
SH3 and multiple ankyrin repeat domains protein 2 (SHANK2) — SH3 and multiple ankyrin repeat domains protein 2 — human protein (gene SHANK2, 1849 amino acids, UniProt Q9UPX8). AlphaFold-predicted 3D structure; by default coloured by model confidence (blue = very high, orange = very low, typical of disordered regions).
PRKCA-binding protein (PICK1) — PRKCA-binding protein — human protein (gene PICK1, 415 amino acids, UniProt Q9NRD5). AlphaFold-predicted 3D structure; by default coloured by model confidence (blue = very high, orange = very low, typical of disordered regions).
Neuroligin-3 (NLGN3) — Neuroligin-3 — human protein (gene NLGN3, 848 amino acids, UniProt Q9NZ94). AlphaFold-predicted 3D structure; by default coloured by model confidence (blue = very high, orange = very low, typical of disordered regions).
Disks large-associated protein 4 (DLGAP4) — Disks large-associated protein 4 — human protein (gene DLGAP4, 992 amino acids, UniProt Q9Y2H0). AlphaFold-predicted 3D structure; by default coloured by model confidence (blue = very high, orange = very low, typical of disordered regions).
Glutamate receptor-interacting protein 2 (GRIP2) — Glutamate receptor-interacting protein 2 — human protein (gene GRIP2, 1043 amino acids, UniProt Q9C0E4). AlphaFold-predicted 3D structure; by default coloured by model confidence (blue = very high, orange = very low, typical of disordered regions).
Calcium/calmodulin-dependent protein kinase type II subunit alpha (CAMK2A) — Calcium/calmodulin-dependent protein kinase type II subunit alpha — human protein (gene CAMK2A, 478 amino acids, UniProt Q9UQM7). AlphaFold-predicted 3D structure; by default coloured by model confidence (blue = very high, orange = very low, typical of disordered regions).
Neurexin-3-beta (NRXN3) — Neurexin-3-beta — human protein (gene NRXN3, 637 amino acids, UniProt Q9HDB5). AlphaFold-predicted 3D structure; by default coloured by model confidence (blue = very high, orange = very low, typical of disordered regions).
Neurexin-3 (NRXN3) — Neurexin-3 — human protein (gene NRXN3, 1643 amino acids, UniProt Q9Y4C0). AlphaFold-predicted 3D structure; by default coloured by model confidence (blue = very high, orange = very low, typical of disordered regions).
Glutamate receptor-interacting protein 1 (GRIP1) — Glutamate receptor-interacting protein 1 — human protein (gene GRIP1, 1128 amino acids, UniProt Q9Y3R0). AlphaFold-predicted 3D structure; by default coloured by model confidence (blue = very high, orange = very low, typical of disordered regions).
Neurexin-2 (NRXN2) — Neurexin-2 — human protein (gene NRXN2, 1712 amino acids, UniProt Q9P2S2). AlphaFold-predicted 3D structure; by default coloured by model confidence (blue = very high, orange = very low, typical of disordered regions).
Gephyrin [Includes: Molybdopterin adenylyltransferase (GPHN) — Gephyrin [Includes: Molybdopterin adenylyltransferase — human protein (gene GPHN, 736 amino acids, UniProt Q9NQX3). AlphaFold-predicted 3D structure; by default coloured by model confidence (blue = very high, orange = very low, typical of disordered regions).
Neurexin-1 (NRXN1) — Neurexin-1 — human protein (gene NRXN1, 1477 amino acids, UniProt Q9ULB1). AlphaFold-predicted 3D structure; by default coloured by model confidence (blue = very high, orange = very low, typical of disordered regions).
Cyclin-dependent kinase 5 activator 1 (CDK5R1) — Cyclin-dependent kinase 5 activator 1 — human protein (gene CDK5R1, 307 amino acids, UniProt Q15078). AlphaFold-predicted 3D structure; by default coloured by model confidence (blue = very high, orange = very low, typical of disordered regions).
Beta-synuclein (SNCB) — Beta-synuclein — human protein (gene SNCB, 134 amino acids, UniProt Q16143). AlphaFold-predicted 3D structure; by default coloured by model confidence (blue = very high, orange = very low, typical of disordered regions).
Vacuolar protein sorting-associated protein 35 (VPS35) — Vacuolar protein sorting-associated protein 35 — human protein (gene VPS35, 796 amino acids, UniProt Q96QK1). AlphaFold-predicted 3D structure; by default coloured by model confidence (blue = very high, orange = very low, typical of disordered regions).
Endophilin-A1 (SH3GL2) — Endophilin-A1 — human protein (gene SH3GL2, 352 amino acids, UniProt Q99962). AlphaFold-predicted 3D structure; by default coloured by model confidence (blue = very high, orange = very low, typical of disordered regions).
Endophilin-A3 (SH3GL3) — Endophilin-A3 — human protein (gene SH3GL3, 347 amino acids, UniProt Q99963). AlphaFold-predicted 3D structure; by default coloured by model confidence (blue = very high, orange = very low, typical of disordered regions).
Interleukin-1 receptor accessory protein-like 1 (IL1RAPL1) — Interleukin-1 receptor accessory protein-like 1 — human protein (gene IL1RAPL1, 696 amino acids, UniProt Q9NZN1). AlphaFold-predicted 3D structure; by default coloured by model confidence (blue = very high, orange = very low, typical of disordered regions).
Leucine-rich repeat and fibronectin type III domain-containing protein 1 (LRFN1) — Leucine-rich repeat and fibronectin type III domain-containing protein 1 — human protein (gene LRFN1, 771 amino acids, UniProt Q9P244). AlphaFold-predicted 3D structure; by default coloured by model confidence (blue = very high, orange = very low, typical of disordered regions).