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Human proteins (AlphaFold) · Ubiquitin & proteasome: 200 3D models

DNA, RNA, nucleic-acid drugs, gene editing, proteins and 300+ real PDB structures (real sizes 1–100 nm). Each one is a ready-made 3D model you can turn, recolour and place in a figure — open BioDioRama and type its name in the Library search.

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E3 ubiquitin-protein ligase TM129 (TMEM129) — E3 ubiquitin-protein ligase TM129 — human protein (gene TMEM129, 362 amino acids, UniProt A0AVI4). AlphaFold-predicted 3D structure; by default coloured by model confidence (blue = very high, orange = very low, typical of disordered regions).
Ubiquitin-like modifier-activating enzyme 6 (UBA6) — Ubiquitin-like modifier-activating enzyme 6 — human protein (gene UBA6, 1052 amino acids, UniProt A0AVT1). AlphaFold-predicted 3D structure; by default coloured by model confidence (blue = very high, orange = very low, typical of disordered regions).
Ubiquitin-conjugating enzyme E2Q-like protein 1 (UBE2QL1) — Ubiquitin-conjugating enzyme E2Q-like protein 1 — human protein (gene UBE2QL1, 161 amino acids, UniProt A1L167). AlphaFold-predicted 3D structure; by default coloured by model confidence (blue = very high, orange = very low, typical of disordered regions).
Zinc finger SWIM domain-containing protein 8 (ZSWIM8) — Zinc finger SWIM domain-containing protein 8 — human protein (gene ZSWIM8, 1837 amino acids, UniProt A7E2V4). AlphaFold-predicted 3D structure; by default coloured by model confidence (blue = very high, orange = very low, typical of disordered regions).
E3 ubiquitin-protein ligase NEURL1B (NEURL1B) — E3 ubiquitin-protein ligase NEURL1B — human protein (gene NEURL1B, 555 amino acids, UniProt A8MQ27). AlphaFold-predicted 3D structure; by default coloured by model confidence (blue = very high, orange = very low, typical of disordered regions).
Kelch repeat and BTB domain-containing protein 13 (KBTBD13) — Kelch repeat and BTB domain-containing protein 13 — human protein (gene KBTBD13, 458 amino acids, UniProt C9JR72). AlphaFold-predicted 3D structure; by default coloured by model confidence (blue = very high, orange = very low, typical of disordered regions).
Small ubiquitin-related modifier 5 (SUMO1P1) — Small ubiquitin-related modifier 5 — human protein (gene SUMO1P1, 101 amino acids, UniProt G2XKQ0). AlphaFold-predicted 3D structure; by default coloured by model confidence (blue = very high, orange = very low, typical of disordered regions).
E3 ubiquitin-protein ligase RNF103 (RNF103) — E3 ubiquitin-protein ligase RNF103 — human protein (gene RNF103, 685 amino acids, UniProt O00237). AlphaFold-predicted 3D structure; by default coloured by model confidence (blue = very high, orange = very low, typical of disordered regions).
E3 SUMO-protein ligase CBX4 (CBX4) — E3 SUMO-protein ligase CBX4 — human protein (gene CBX4, 560 amino acids, UniProt O00257). AlphaFold-predicted 3D structure; by default coloured by model confidence (blue = very high, orange = very low, typical of disordered regions).
NEDD4-like E3 ubiquitin-protein ligase WWP2 (WWP2) — NEDD4-like E3 ubiquitin-protein ligase WWP2 — human protein (gene WWP2, 870 amino acids, UniProt O00308). AlphaFold-predicted 3D structure; by default coloured by model confidence (blue = very high, orange = very low, typical of disordered regions).
Ubiquitin-conjugating enzyme E2 C (UBE2C) — Ubiquitin-conjugating enzyme E2 C — human protein (gene UBE2C, 179 amino acids, UniProt O00762). AlphaFold-predicted 3D structure; by default coloured by model confidence (blue = very high, orange = very low, typical of disordered regions).
Suppressor of cytokine signaling 2 (SOCS2) — Suppressor of cytokine signaling 2 — human protein (gene SOCS2, 198 amino acids, UniProt O14508). AlphaFold-predicted 3D structure; by default coloured by model confidence (blue = very high, orange = very low, typical of disordered regions).
Suppressor of cytokine signaling 7 (SOCS7) — Suppressor of cytokine signaling 7 — human protein (gene SOCS7, 581 amino acids, UniProt O14512). AlphaFold-predicted 3D structure; by default coloured by model confidence (blue = very high, orange = very low, typical of disordered regions).
Suppressor of cytokine signaling 3 (SOCS3) — Suppressor of cytokine signaling 3 — human protein (gene SOCS3, 225 amino acids, UniProt O14543). AlphaFold-predicted 3D structure; by default coloured by model confidence (blue = very high, orange = very low, typical of disordered regions).
Suppressor of cytokine signaling 6 (SOCS6) — Suppressor of cytokine signaling 6 — human protein (gene SOCS6, 535 amino acids, UniProt O14544). AlphaFold-predicted 3D structure; by default coloured by model confidence (blue = very high, orange = very low, typical of disordered regions).
Ubiquitin/ISG15-conjugating enzyme E2 L6 (UBE2L6) — Ubiquitin/ISG15-conjugating enzyme E2 L6 — human protein (gene UBE2L6, 153 amino acids, UniProt O14933). AlphaFold-predicted 3D structure; by default coloured by model confidence (blue = very high, orange = very low, typical of disordered regions).
Apoptosis-resistant E3 ubiquitin protein ligase 1 (AREL1) — Apoptosis-resistant E3 ubiquitin protein ligase 1 — human protein (gene AREL1, 823 amino acids, UniProt O15033). AlphaFold-predicted 3D structure; by default coloured by model confidence (blue = very high, orange = very low, typical of disordered regions).
Ubiquitin D (UBD) — Ubiquitin D — human protein (gene UBD, 165 amino acids, UniProt O15205). AlphaFold-predicted 3D structure; by default coloured by model confidence (blue = very high, orange = very low, typical of disordered regions).
UDP-N-acetylglucosamine--peptide N-acetylglucosaminyltransferase 110 kDa subunit (OGT) — UDP-N-acetylglucosamine--peptide N-acetylglucosaminyltransferase 110 kDa subunit — human protein (gene OGT, 1046 amino acids, UniProt O15294). AlphaFold-predicted 3D structure; by default coloured by model confidence (blue = very high, orange = very low, typical of disordered regions).
Melanoma-associated antigen B2 (MAGEB2) — Melanoma-associated antigen B2 — human protein (gene MAGEB2, 319 amino acids, UniProt O15479). AlphaFold-predicted 3D structure; by default coloured by model confidence (blue = very high, orange = very low, typical of disordered regions).
Suppressor of cytokine signaling 1 (SOCS1) — Suppressor of cytokine signaling 1 — human protein (gene SOCS1, 211 amino acids, UniProt O15524). AlphaFold-predicted 3D structure; by default coloured by model confidence (blue = very high, orange = very low, typical of disordered regions).
E3 ubiquitin-protein ligase RNF113A (RNF113A) — E3 ubiquitin-protein ligase RNF113A — human protein (gene RNF113A, 343 amino acids, UniProt O15541). AlphaFold-predicted 3D structure; by default coloured by model confidence (blue = very high, orange = very low, typical of disordered regions).
E3 ubiquitin-protein ligase SIAH2 (SIAH2) — E3 ubiquitin-protein ligase SIAH2 — human protein (gene SIAH2, 324 amino acids, UniProt O43255). AlphaFold-predicted 3D structure; by default coloured by model confidence (blue = very high, orange = very low, typical of disordered regions).
E3 ubiquitin-protein ligase RNF13 (RNF13) — E3 ubiquitin-protein ligase RNF13 — human protein (gene RNF13, 381 amino acids, UniProt O43567). AlphaFold-predicted 3D structure; by default coloured by model confidence (blue = very high, orange = very low, typical of disordered regions).
E3 ubiquitin ligase TRAF3IP2 (TRAF3IP2) — E3 ubiquitin ligase TRAF3IP2 — human protein (gene TRAF3IP2, 574 amino acids, UniProt O43734). AlphaFold-predicted 3D structure; by default coloured by model confidence (blue = very high, orange = very low, typical of disordered regions).
Speckle-type POZ protein (SPOP) — Speckle-type POZ protein — human protein (gene SPOP, 374 amino acids, UniProt O43791). AlphaFold-predicted 3D structure; by default coloured by model confidence (blue = very high, orange = very low, typical of disordered regions).
E3 ubiquitin-protein ligase parkin (PRKN) — E3 ubiquitin-protein ligase parkin — human protein (gene PRKN, 465 amino acids, UniProt O60260). AlphaFold-predicted 3D structure; by default coloured by model confidence (blue = very high, orange = very low, typical of disordered regions).
E3 ubiquitin-protein ligase MGRN1 (MGRN1) — E3 ubiquitin-protein ligase MGRN1 — human protein (gene MGRN1, 552 amino acids, UniProt O60291). AlphaFold-predicted 3D structure; by default coloured by model confidence (blue = very high, orange = very low, typical of disordered regions).
E3 ubiquitin-protein ligase MARCHF6 (MARCHF6) — E3 ubiquitin-protein ligase MARCHF6 — human protein (gene MARCHF6, 910 amino acids, UniProt O60337). AlphaFold-predicted 3D structure; by default coloured by model confidence (blue = very high, orange = very low, typical of disordered regions).
F-box-like/WD repeat-containing protein TBL1X (TBL1X) — F-box-like/WD repeat-containing protein TBL1X — human protein (gene TBL1X, 577 amino acids, UniProt O60907). AlphaFold-predicted 3D structure; by default coloured by model confidence (blue = very high, orange = very low, typical of disordered regions).
E3 ubiquitin-protein ligase PPP1R11 (PPP1R11) — E3 ubiquitin-protein ligase PPP1R11 — human protein (gene PPP1R11, 126 amino acids, UniProt O60927). AlphaFold-predicted 3D structure; by default coloured by model confidence (blue = very high, orange = very low, typical of disordered regions).
E3 ubiquitin-protein ligase BRE1B (RNF40) — E3 ubiquitin-protein ligase BRE1B — human protein (gene RNF40, 1001 amino acids, UniProt O75150). AlphaFold-predicted 3D structure; by default coloured by model confidence (blue = very high, orange = very low, typical of disordered regions).
Cullin-associated NEDD8-dissociated protein 2 (CAND2) — Cullin-associated NEDD8-dissociated protein 2 — human protein (gene CAND2, 1236 amino acids, UniProt O75155). AlphaFold-predicted 3D structure; by default coloured by model confidence (blue = very high, orange = very low, typical of disordered regions).
Suppressor of cytokine signaling 5 (SOCS5) — Suppressor of cytokine signaling 5 — human protein (gene SOCS5, 536 amino acids, UniProt O75159). AlphaFold-predicted 3D structure; by default coloured by model confidence (blue = very high, orange = very low, typical of disordered regions).
F-box only protein 24 (FBXO24) — F-box only protein 24 — human protein (gene FBXO24, 580 amino acids, UniProt O75426). AlphaFold-predicted 3D structure; by default coloured by model confidence (blue = very high, orange = very low, typical of disordered regions).
E3 ubiquitin-protein ligase NEURL1 (NEURL1) — E3 ubiquitin-protein ligase NEURL1 — human protein (gene NEURL1, 574 amino acids, UniProt O76050). AlphaFold-predicted 3D structure; by default coloured by model confidence (blue = very high, orange = very low, typical of disordered regions).
E3 ubiquitin-protein ligase RNF8 (RNF8) — E3 ubiquitin-protein ligase RNF8 — human protein (gene RNF8, 485 amino acids, UniProt O76064). AlphaFold-predicted 3D structure; by default coloured by model confidence (blue = very high, orange = very low, typical of disordered regions).
Ubiquitin-like protein ATG12 (ATG12) — Ubiquitin-like protein ATG12 — human protein (gene ATG12, 140 amino acids, UniProt O94817). AlphaFold-predicted 3D structure; by default coloured by model confidence (blue = very high, orange = very low, typical of disordered regions).
E3 ubiquitin-protein ligase listerin (LTN1) — E3 ubiquitin-protein ligase listerin — human protein (gene LTN1, 1766 amino acids, UniProt O94822). AlphaFold-predicted 3D structure; by default coloured by model confidence (blue = very high, orange = very low, typical of disordered regions).
E3 UFM1-protein ligase 1 (UFL1) — E3 UFM1-protein ligase 1 — human protein (gene UFL1, 794 amino acids, UniProt O94874). AlphaFold-predicted 3D structure; by default coloured by model confidence (blue = very high, orange = very low, typical of disordered regions).
Kelch-like protein 18 (KLHL18) — Kelch-like protein 18 — human protein (gene KLHL18, 574 amino acids, UniProt O94889). AlphaFold-predicted 3D structure; by default coloured by model confidence (blue = very high, orange = very low, typical of disordered regions).
RING finger protein 37 (UBOX5) — RING finger protein 37 — human protein (gene UBOX5, 541 amino acids, UniProt O94941). AlphaFold-predicted 3D structure; by default coloured by model confidence (blue = very high, orange = very low, typical of disordered regions).
E3 ubiquitin-protein ligase TRIM37 (TRIM37) — E3 ubiquitin-protein ligase TRIM37 — human protein (gene TRIM37, 964 amino acids, UniProt O94972). AlphaFold-predicted 3D structure; by default coloured by model confidence (blue = very high, orange = very low, typical of disordered regions).
Ubiquitin conjugation factor E4 B (UBE4B) — Ubiquitin conjugation factor E4 B — human protein (gene UBE4B, 1302 amino acids, UniProt O95155). AlphaFold-predicted 3D structure; by default coloured by model confidence (blue = very high, orange = very low, typical of disordered regions).
Arginyl-tRNA--protein transferase 1 (ATE1) — Arginyl-tRNA--protein transferase 1 — human protein (gene ATE1, 518 amino acids, UniProt O95260). AlphaFold-predicted 3D structure; by default coloured by model confidence (blue = very high, orange = very low, typical of disordered regions).
Ubiquitin-like modifier-activating enzyme ATG7 (ATG7) — Ubiquitin-like modifier-activating enzyme ATG7 — human protein (gene ATG7, 703 amino acids, UniProt O95352). AlphaFold-predicted 3D structure; by default coloured by model confidence (blue = very high, orange = very low, typical of disordered regions).
E3 ubiquitin-protein ligase TRIM16 (TRIM16) — E3 ubiquitin-protein ligase TRIM16 — human protein (gene TRIM16, 564 amino acids, UniProt O95361). AlphaFold-predicted 3D structure; by default coloured by model confidence (blue = very high, orange = very low, typical of disordered regions).
E3 ubiquitin-protein ligase ARIH2 (ARIH2) — E3 ubiquitin-protein ligase ARIH2 — human protein (gene ARIH2, 493 amino acids, UniProt O95376). AlphaFold-predicted 3D structure; by default coloured by model confidence (blue = very high, orange = very low, typical of disordered regions).
CCR4-NOT transcription complex subunit 4 (CNOT4) — CCR4-NOT transcription complex subunit 4 — human protein (gene CNOT4, 575 amino acids, UniProt O95628). AlphaFold-predicted 3D structure; by default coloured by model confidence (blue = very high, orange = very low, typical of disordered regions).
Ras-related protein Rab-40A-like (RAB40AL) — Ras-related protein Rab-40A-like — human protein (gene RAB40AL, 278 amino acids, UniProt P0C0E4). AlphaFold-predicted 3D structure; by default coloured by model confidence (blue = very high, orange = very low, typical of disordered regions).
F-box/SPRY domain-containing protein 1 (FBXO45) — F-box/SPRY domain-containing protein 1 — human protein (gene FBXO45, 286 amino acids, UniProt P0C2W1). AlphaFold-predicted 3D structure; by default coloured by model confidence (blue = very high, orange = very low, typical of disordered regions).
V(D)J recombination-activating protein 1 (RAG1) — V(D)J recombination-activating protein 1 — human protein (gene RAG1, 1043 amino acids, UniProt P15918). AlphaFold-predicted 3D structure; by default coloured by model confidence (blue = very high, orange = very low, typical of disordered regions).
E3 ubiquitin-protein ligase TRIM21 (TRIM21) — E3 ubiquitin-protein ligase TRIM21 — human protein (gene TRIM21, 475 amino acids, UniProt P19474). AlphaFold-predicted 3D structure; by default coloured by model confidence (blue = very high, orange = very low, typical of disordered regions).
Ubiquitin-like modifier-activating enzyme 1 (UBA1) — Ubiquitin-like modifier-activating enzyme 1 — human protein (gene UBA1, 1058 amino acids, UniProt P22314). AlphaFold-predicted 3D structure; by default coloured by model confidence (blue = very high, orange = very low, typical of disordered regions).
E3 ubiquitin-protein ligase CBL (CBL) — E3 ubiquitin-protein ligase CBL — human protein (gene CBL, 906 amino acids, UniProt P22681). AlphaFold-predicted 3D structure; by default coloured by model confidence (blue = very high, orange = very low, typical of disordered regions).
Breast cancer type 1 susceptibility protein (BRCA1) — Breast cancer type 1 susceptibility protein — human protein (gene BRCA1, 1863 amino acids, UniProt P38398). AlphaFold-predicted 3D structure; by default coloured by model confidence (blue = very high, orange = very low, typical of disordered regions).
von Hippel-Lindau disease tumor suppressor (VHL) — von Hippel-Lindau disease tumor suppressor — human protein (gene VHL, 213 amino acids, UniProt P40337). AlphaFold-predicted 3D structure; by default coloured by model confidence (blue = very high, orange = very low, typical of disordered regions).
Cyclin-F (CCNF) — Cyclin-F — human protein (gene CCNF, 786 amino acids, UniProt P41002). AlphaFold-predicted 3D structure; by default coloured by model confidence (blue = very high, orange = very low, typical of disordered regions).
Ubiquitin-like modifier-activating enzyme 7 (UBA7) — Ubiquitin-like modifier-activating enzyme 7 — human protein (gene UBA7, 1012 amino acids, UniProt P41226). AlphaFold-predicted 3D structure; by default coloured by model confidence (blue = very high, orange = very low, typical of disordered regions).
Melanoma-associated antigen 2 (MAGEA2; MAGEA2B) — Melanoma-associated antigen 2 — human protein (gene MAGEA2; MAGEA2B, 314 amino acids, UniProt P43356). AlphaFold-predicted 3D structure; by default coloured by model confidence (blue = very high, orange = very low, typical of disordered regions).
Melanoma-associated antigen 3 (MAGEA3) — Melanoma-associated antigen 3 — human protein (gene MAGEA3, 314 amino acids, UniProt P43357). AlphaFold-predicted 3D structure; by default coloured by model confidence (blue = very high, orange = very low, typical of disordered regions).
Melanoma-associated antigen 6 (MAGEA6) — Melanoma-associated antigen 6 — human protein (gene MAGEA6, 314 amino acids, UniProt P43360). AlphaFold-predicted 3D structure; by default coloured by model confidence (blue = very high, orange = very low, typical of disordered regions).
E3 ubiquitin-protein ligase NEDD4 (NEDD4) — E3 ubiquitin-protein ligase NEDD4 — human protein (gene NEDD4, 1319 amino acids, UniProt P46934). AlphaFold-predicted 3D structure; by default coloured by model confidence (blue = very high, orange = very low, typical of disordered regions).
Ubiquitin-conjugating enzyme E2 R1 (CDC34) — Ubiquitin-conjugating enzyme E2 R1 — human protein (gene CDC34, 236 amino acids, UniProt P49427). AlphaFold-predicted 3D structure; by default coloured by model confidence (blue = very high, orange = very low, typical of disordered regions).
Ubiquitin-conjugating enzyme E2 A (UBE2A) — Ubiquitin-conjugating enzyme E2 A — human protein (gene UBE2A, 152 amino acids, UniProt P49459). AlphaFold-predicted 3D structure; by default coloured by model confidence (blue = very high, orange = very low, typical of disordered regions).
E3 ubiquitin-protein ligase RNF144A (RNF144A) — E3 ubiquitin-protein ligase RNF144A — human protein (gene RNF144A, 292 amino acids, UniProt P50876). AlphaFold-predicted 3D structure; by default coloured by model confidence (blue = very high, orange = very low, typical of disordered regions).
Ubiquitin-conjugating enzyme E2 D1 (UBE2D1) — Ubiquitin-conjugating enzyme E2 D1 — human protein (gene UBE2D1, 147 amino acids, UniProt P51668). AlphaFold-predicted 3D structure; by default coloured by model confidence (blue = very high, orange = very low, typical of disordered regions).
Ubiquitin-conjugating enzyme E2 E1 (UBE2E1) — Ubiquitin-conjugating enzyme E2 E1 — human protein (gene UBE2E1, 193 amino acids, UniProt P51965). AlphaFold-predicted 3D structure; by default coloured by model confidence (blue = very high, orange = very low, typical of disordered regions).
E3 ubiquitin-protein ligase TTC3 (TTC3) — E3 ubiquitin-protein ligase TTC3 — human protein (gene TTC3, 2025 amino acids, UniProt P53804). AlphaFold-predicted 3D structure; by default coloured by model confidence (blue = very high, orange = very low, typical of disordered regions).
Lysine-specific demethylase RAD23B (RAD23B) — Lysine-specific demethylase RAD23B — human protein (gene RAD23B, 409 amino acids, UniProt P54727). AlphaFold-predicted 3D structure; by default coloured by model confidence (blue = very high, orange = very low, typical of disordered regions).
Transitional endoplasmic reticulum ATPase (VCP) — Transitional endoplasmic reticulum ATPase — human protein (gene VCP, 806 amino acids, UniProt P55072). AlphaFold-predicted 3D structure; by default coloured by model confidence (blue = very high, orange = very low, typical of disordered regions).
Small ubiquitin-related modifier 3 (SUMO3) — Small ubiquitin-related modifier 3 — human protein (gene SUMO3, 103 amino acids, UniProt P55854). AlphaFold-predicted 3D structure; by default coloured by model confidence (blue = very high, orange = very low, typical of disordered regions).
Ubiquitin-conjugating enzyme E2 G2 (UBE2G2) — Ubiquitin-conjugating enzyme E2 G2 — human protein (gene UBE2G2, 165 amino acids, UniProt P60604). AlphaFold-predicted 3D structure; by default coloured by model confidence (blue = very high, orange = very low, typical of disordered regions).
Ubiquitin-conjugating enzyme E2 D3 (UBE2D3) — Ubiquitin-conjugating enzyme E2 D3 — human protein (gene UBE2D3, 147 amino acids, UniProt P61077). AlphaFold-predicted 3D structure; by default coloured by model confidence (blue = very high, orange = very low, typical of disordered regions).
NEDD8-conjugating enzyme Ubc12 (UBE2M) — NEDD8-conjugating enzyme Ubc12 — human protein (gene UBE2M, 183 amino acids, UniProt P61081). AlphaFold-predicted 3D structure; by default coloured by model confidence (blue = very high, orange = very low, typical of disordered regions).
Ubiquitin-conjugating enzyme E2 K (UBE2K) — Ubiquitin-conjugating enzyme E2 K — human protein (gene UBE2K, 200 amino acids, UniProt P61086). AlphaFold-predicted 3D structure; by default coloured by model confidence (blue = very high, orange = very low, typical of disordered regions).
Ubiquitin-conjugating enzyme E2 N (UBE2N) — Ubiquitin-conjugating enzyme E2 N — human protein (gene UBE2N, 152 amino acids, UniProt P61088). AlphaFold-predicted 3D structure; by default coloured by model confidence (blue = very high, orange = very low, typical of disordered regions).
Small ubiquitin-related modifier 2 (SUMO2) — Small ubiquitin-related modifier 2 — human protein (gene SUMO2, 95 amino acids, UniProt P61956). AlphaFold-predicted 3D structure; by default coloured by model confidence (blue = very high, orange = very low, typical of disordered regions).
Ubiquitin-fold modifier 1 (UFM1) — Ubiquitin-fold modifier 1 — human protein (gene UFM1, 85 amino acids, UniProt P61960). AlphaFold-predicted 3D structure; by default coloured by model confidence (blue = very high, orange = very low, typical of disordered regions).
DDB1- and CUL4-associated factor 7 (DCAF7) — DDB1- and CUL4-associated factor 7 — human protein (gene DCAF7, 342 amino acids, UniProt P61962). AlphaFold-predicted 3D structure; by default coloured by model confidence (blue = very high, orange = very low, typical of disordered regions).
Ubiquitin-conjugating enzyme E2 G1 (UBE2G1) — Ubiquitin-conjugating enzyme E2 G1 — human protein (gene UBE2G1, 170 amino acids, UniProt P62253). AlphaFold-predicted 3D structure; by default coloured by model confidence (blue = very high, orange = very low, typical of disordered regions).
Ubiquitin-conjugating enzyme E2 H (UBE2H) — Ubiquitin-conjugating enzyme E2 H — human protein (gene UBE2H, 183 amino acids, UniProt P62256). AlphaFold-predicted 3D structure; by default coloured by model confidence (blue = very high, orange = very low, typical of disordered regions).
Ubiquitin-conjugating enzyme E2 D2 (UBE2D2) — Ubiquitin-conjugating enzyme E2 D2 — human protein (gene UBE2D2, 147 amino acids, UniProt P62837). AlphaFold-predicted 3D structure; by default coloured by model confidence (blue = very high, orange = very low, typical of disordered regions).
E3 ubiquitin-protein ligase RBX1 (RBX1) — E3 ubiquitin-protein ligase RBX1 — human protein (gene RBX1, 108 amino acids, UniProt P62877). AlphaFold-predicted 3D structure; by default coloured by model confidence (blue = very high, orange = very low, typical of disordered regions).
Ubiquitin-conjugating enzyme E2 B (UBE2B) — Ubiquitin-conjugating enzyme E2 B — human protein (gene UBE2B, 152 amino acids, UniProt P63146). AlphaFold-predicted 3D structure; by default coloured by model confidence (blue = very high, orange = very low, typical of disordered regions).
Small ubiquitin-related modifier 1 (SUMO1) — Small ubiquitin-related modifier 1 — human protein (gene SUMO1, 101 amino acids, UniProt P63165). AlphaFold-predicted 3D structure; by default coloured by model confidence (blue = very high, orange = very low, typical of disordered regions).
S-phase kinase-associated protein 1 (SKP1) — S-phase kinase-associated protein 1 — human protein (gene SKP1, 163 amino acids, UniProt P63208). AlphaFold-predicted 3D structure; by default coloured by model confidence (blue = very high, orange = very low, typical of disordered regions).
SUMO-conjugating enzyme UBC9 (UBE2I) — SUMO-conjugating enzyme UBC9 — human protein (gene UBE2I, 158 amino acids, UniProt P63279). AlphaFold-predicted 3D structure; by default coloured by model confidence (blue = very high, orange = very low, typical of disordered regions).
Ubiquitin-conjugating enzyme E2 L3 (UBE2L3) — Ubiquitin-conjugating enzyme E2 L3 — human protein (gene UBE2L3, 154 amino acids, UniProt P68036). AlphaFold-predicted 3D structure; by default coloured by model confidence (blue = very high, orange = very low, typical of disordered regions).
E3 ubiquitin-protein ligase RNF4 (RNF4) — E3 ubiquitin-protein ligase RNF4 — human protein (gene RNF4, 190 amino acids, UniProt P78317). AlphaFold-predicted 3D structure; by default coloured by model confidence (blue = very high, orange = very low, typical of disordered regions).
Melanoma antigen preferentially expressed in tumors (PRAME) — Melanoma antigen preferentially expressed in tumors — human protein (gene PRAME, 509 amino acids, UniProt P78395). AlphaFold-predicted 3D structure; by default coloured by model confidence (blue = very high, orange = very low, typical of disordered regions).
Forkhead box protein K1 (FOXK1) — Forkhead box protein K1 — human protein (gene FOXK1, 733 amino acids, UniProt P85037). AlphaFold-predicted 3D structure; by default coloured by model confidence (blue = very high, orange = very low, typical of disordered regions).
E3 ubiquitin-protein ligase XIAP (XIAP) — E3 ubiquitin-protein ligase XIAP — human protein (gene XIAP, 497 amino acids, UniProt P98170). AlphaFold-predicted 3D structure; by default coloured by model confidence (blue = very high, orange = very low, typical of disordered regions).
E3 ubiquitin-protein ligase Mdm2 (MDM2) — E3 ubiquitin-protein ligase Mdm2 — human protein (gene MDM2, 491 amino acids, UniProt Q00987). AlphaFold-predicted 3D structure; by default coloured by model confidence (blue = very high, orange = very low, typical of disordered regions).
Forkhead box protein K2 (FOXK2) — Forkhead box protein K2 — human protein (gene FOXK2, 660 amino acids, UniProt Q01167). AlphaFold-predicted 3D structure; by default coloured by model confidence (blue = very high, orange = very low, typical of disordered regions).
Ubiquitin-protein ligase E3A (UBE3A) — Ubiquitin-protein ligase E3A — human protein (gene UBE3A, 875 amino acids, UniProt Q05086). AlphaFold-predicted 3D structure; by default coloured by model confidence (blue = very high, orange = very low, typical of disordered regions).
Zinc finger and BTB domain-containing protein 16 (ZBTB16) — Zinc finger and BTB domain-containing protein 16 — human protein (gene ZBTB16, 673 amino acids, UniProt Q05516). AlphaFold-predicted 3D structure; by default coloured by model confidence (blue = very high, orange = very low, typical of disordered regions).
E3 ubiquitin-protein ligase RING1 (RING1) — E3 ubiquitin-protein ligase RING1 — human protein (gene RING1, 406 amino acids, UniProt Q06587). AlphaFold-predicted 3D structure; by default coloured by model confidence (blue = very high, orange = very low, typical of disordered regions).
Ras-related protein Rab-40B (RAB40B) — Ras-related protein Rab-40B — human protein (gene RAB40B, 278 amino acids, UniProt Q12829). AlphaFold-predicted 3D structure; by default coloured by model confidence (blue = very high, orange = very low, typical of disordered regions).
Cell division cycle protein 20 homolog (CDC20) — Cell division cycle protein 20 homolog — human protein (gene CDC20, 499 amino acids, UniProt Q12834). AlphaFold-predicted 3D structure; by default coloured by model confidence (blue = very high, orange = very low, typical of disordered regions).
TNF receptor-associated factor 2 (TRAF2) — TNF receptor-associated factor 2 — human protein (gene TRAF2, 501 amino acids, UniProt Q12933). AlphaFold-predicted 3D structure; by default coloured by model confidence (blue = very high, orange = very low, typical of disordered regions).
Transcriptional repressor NF-X1 (NFX1) — Transcriptional repressor NF-X1 — human protein (gene NFX1, 1120 amino acids, UniProt Q12986). AlphaFold-predicted 3D structure; by default coloured by model confidence (blue = very high, orange = very low, typical of disordered regions).
Cell division cycle protein 16 homolog (CDC16) — Cell division cycle protein 16 homolog — human protein (gene CDC16, 620 amino acids, UniProt Q13042). AlphaFold-predicted 3D structure; by default coloured by model confidence (blue = very high, orange = very low, typical of disordered regions).
E3 ubiquitin-protein ligase TRIM32 (TRIM32) — E3 ubiquitin-protein ligase TRIM32 — human protein (gene TRIM32, 653 amino acids, UniProt Q13049). AlphaFold-predicted 3D structure; by default coloured by model confidence (blue = very high, orange = very low, typical of disordered regions).
E3 ubiquitin-protein ligase makorin-3 (MKRN3) — E3 ubiquitin-protein ligase makorin-3 — human protein (gene MKRN3, 507 amino acids, UniProt Q13064). AlphaFold-predicted 3D structure; by default coloured by model confidence (blue = very high, orange = very low, typical of disordered regions).
TNF receptor-associated factor 3 (TRAF3) — TNF receptor-associated factor 3 — human protein (gene TRAF3, 568 amino acids, UniProt Q13114). AlphaFold-predicted 3D structure; by default coloured by model confidence (blue = very high, orange = very low, typical of disordered regions).
E3 ubiquitin-protein ligase CBL-B (CBLB) — E3 ubiquitin-protein ligase CBL-B — human protein (gene CBLB, 982 amino acids, UniProt Q13191). AlphaFold-predicted 3D structure; by default coloured by model confidence (blue = very high, orange = very low, typical of disordered regions).
DNA excision repair protein ERCC-8 (ERCC8) — DNA excision repair protein ERCC-8 — human protein (gene ERCC8, 396 amino acids, UniProt Q13216). AlphaFold-predicted 3D structure; by default coloured by model confidence (blue = very high, orange = very low, typical of disordered regions).
Transcription intermediary factor 1-beta (TRIM28) — Transcription intermediary factor 1-beta — human protein (gene TRIM28, 835 amino acids, UniProt Q13263). AlphaFold-predicted 3D structure; by default coloured by model confidence (blue = very high, orange = very low, typical of disordered regions).
S-phase kinase-associated protein 2 (SKP2) — S-phase kinase-associated protein 2 — human protein (gene SKP2, 424 amino acids, UniProt Q13309). AlphaFold-predicted 3D structure; by default coloured by model confidence (blue = very high, orange = very low, typical of disordered regions).
RING-type E3 ubiquitin-protein ligase PPIL2 (PPIL2) — RING-type E3 ubiquitin-protein ligase PPIL2 — human protein (gene PPIL2, 520 amino acids, UniProt Q13356). AlphaFold-predicted 3D structure; by default coloured by model confidence (blue = very high, orange = very low, typical of disordered regions).
Ubiquitin-conjugating enzyme E2 variant 1 (UBE2V1) — Ubiquitin-conjugating enzyme E2 variant 1 — human protein (gene UBE2V1, 147 amino acids, UniProt Q13404). AlphaFold-predicted 3D structure; by default coloured by model confidence (blue = very high, orange = very low, typical of disordered regions).
Baculoviral IAP repeat-containing protein 3 (BIRC3) — Baculoviral IAP repeat-containing protein 3 — human protein (gene BIRC3, 604 amino acids, UniProt Q13489). AlphaFold-predicted 3D structure; by default coloured by model confidence (blue = very high, orange = very low, typical of disordered regions).
Baculoviral IAP repeat-containing protein 2 (BIRC2) — Baculoviral IAP repeat-containing protein 2 — human protein (gene BIRC2, 618 amino acids, UniProt Q13490). AlphaFold-predicted 3D structure; by default coloured by model confidence (blue = very high, orange = very low, typical of disordered regions).
NEDD8-activating enzyme E1 regulatory subunit (NAE1) — NEDD8-activating enzyme E1 regulatory subunit — human protein (gene NAE1, 534 amino acids, UniProt Q13564). AlphaFold-predicted 3D structure; by default coloured by model confidence (blue = very high, orange = very low, typical of disordered regions).
Cullin-1 (CUL1) — Cullin-1 — human protein (gene CUL1, 776 amino acids, UniProt Q13616). AlphaFold-predicted 3D structure; by default coloured by model confidence (blue = very high, orange = very low, typical of disordered regions).
Cullin-2 (CUL2) — Cullin-2 — human protein (gene CUL2, 745 amino acids, UniProt Q13617). AlphaFold-predicted 3D structure; by default coloured by model confidence (blue = very high, orange = very low, typical of disordered regions).
Cullin-3 (CUL3) — Cullin-3 — human protein (gene CUL3, 768 amino acids, UniProt Q13618). AlphaFold-predicted 3D structure; by default coloured by model confidence (blue = very high, orange = very low, typical of disordered regions).
Cullin-4A (CUL4A) — Cullin-4A — human protein (gene CUL4A, 759 amino acids, UniProt Q13619). AlphaFold-predicted 3D structure; by default coloured by model confidence (blue = very high, orange = very low, typical of disordered regions).
Cullin-4B (CUL4B) — Cullin-4B — human protein (gene CUL4B, 913 amino acids, UniProt Q13620). AlphaFold-predicted 3D structure; by default coloured by model confidence (blue = very high, orange = very low, typical of disordered regions).
BTB/POZ domain-containing adapter for CUL3-mediated RhoA degradation protein 2 (TNFAIP1) — BTB/POZ domain-containing adapter for CUL3-mediated RhoA degradation protein 2 — human protein (gene TNFAIP1, 316 amino acids, UniProt Q13829). AlphaFold-predicted 3D structure; by default coloured by model confidence (blue = very high, orange = very low, typical of disordered regions).
Ubiquitin conjugation factor E4 A (UBE4A) — Ubiquitin conjugation factor E4 A — human protein (gene UBE4A, 1066 amino acids, UniProt Q14139). AlphaFold-predicted 3D structure; by default coloured by model confidence (blue = very high, orange = very low, typical of disordered regions).
Kelch-like ECH-associated protein 1 (KEAP1) — Kelch-like ECH-associated protein 1 — human protein (gene KEAP1, 624 amino acids, UniProt Q14145). AlphaFold-predicted 3D structure; by default coloured by model confidence (blue = very high, orange = very low, typical of disordered regions).
E3 ubiquitin/ISG15 ligase TRIM25 (TRIM25) — E3 ubiquitin/ISG15 ligase TRIM25 — human protein (gene TRIM25, 630 amino acids, UniProt Q14258). AlphaFold-predicted 3D structure; by default coloured by model confidence (blue = very high, orange = very low, typical of disordered regions).
DNA-dependent ATPase/E3 ubiquitin-protein ligase HLTF (HLTF) — DNA-dependent ATPase/E3 ubiquitin-protein ligase HLTF — human protein (gene HLTF, 1009 amino acids, UniProt Q14527). AlphaFold-predicted 3D structure; by default coloured by model confidence (blue = very high, orange = very low, typical of disordered regions).
E3 ubiquitin-protein ligase TRIP12 (TRIP12) — E3 ubiquitin-protein ligase TRIP12 — human protein (gene TRIP12, 2067 amino acids, UniProt Q14669). AlphaFold-predicted 3D structure; by default coloured by model confidence (blue = very high, orange = very low, typical of disordered regions).
Cullin-7 (CUL7) — Cullin-7 — human protein (gene CUL7, 1698 amino acids, UniProt Q14999). AlphaFold-predicted 3D structure; by default coloured by model confidence (blue = very high, orange = very low, typical of disordered regions).
E3 ubiquitin-protein ligase SHPRH (SHPRH) — E3 ubiquitin-protein ligase SHPRH — human protein (gene SHPRH, 1683 amino acids, UniProt Q149N8). AlphaFold-predicted 3D structure; by default coloured by model confidence (blue = very high, orange = very low, typical of disordered regions).
BRISC complex subunit Abraxas 2 (ABRAXAS2) — BRISC complex subunit Abraxas 2 — human protein (gene ABRAXAS2, 415 amino acids, UniProt Q15018). AlphaFold-predicted 3D structure; by default coloured by model confidence (blue = very high, orange = very low, typical of disordered regions).
Probable E3 ubiquitin-protein ligase HERC3 (HERC3) — Probable E3 ubiquitin-protein ligase HERC3 — human protein (gene HERC3, 1050 amino acids, UniProt Q15034). AlphaFold-predicted 3D structure; by default coloured by model confidence (blue = very high, orange = very low, typical of disordered regions).
Leucine-rich repeat-containing protein 41 (LRRC41) — Leucine-rich repeat-containing protein 41 — human protein (gene LRRC41, 812 amino acids, UniProt Q15345). AlphaFold-predicted 3D structure; by default coloured by model confidence (blue = very high, orange = very low, typical of disordered regions).
Elongin-C (ELOC) — Elongin-C — human protein (gene ELOC, 112 amino acids, UniProt Q15369). AlphaFold-predicted 3D structure; by default coloured by model confidence (blue = very high, orange = very low, typical of disordered regions).
Elongin-B (ELOB) — Elongin-B — human protein (gene ELOB, 118 amino acids, UniProt Q15370). AlphaFold-predicted 3D structure; by default coloured by model confidence (blue = very high, orange = very low, typical of disordered regions).
Ubiquitin-protein ligase E3C (UBE3C) — Ubiquitin-protein ligase E3C — human protein (gene UBE3C, 1083 amino acids, UniProt Q15386). AlphaFold-predicted 3D structure; by default coloured by model confidence (blue = very high, orange = very low, typical of disordered regions).
Ubiquitin-conjugating enzyme E2 variant 2 (UBE2V2) — Ubiquitin-conjugating enzyme E2 variant 2 — human protein (gene UBE2V2, 145 amino acids, UniProt Q15819). AlphaFold-predicted 3D structure; by default coloured by model confidence (blue = very high, orange = very low, typical of disordered regions).
Ubiquitin-like protein NEDD8 (NEDD8) — Ubiquitin-like protein NEDD8 — human protein (gene NEDD8, 81 amino acids, UniProt Q15843). AlphaFold-predicted 3D structure; by default coloured by model confidence (blue = very high, orange = very low, typical of disordered regions).
DNA damage-binding protein 1 (DDB1) — DNA damage-binding protein 1 — human protein (gene DDB1, 1140 amino acids, UniProt Q16531). AlphaFold-predicted 3D structure; by default coloured by model confidence (blue = very high, orange = very low, typical of disordered regions).
Ubiquitin-conjugating enzyme E2 S (UBE2S) — Ubiquitin-conjugating enzyme E2 S — human protein (gene UBE2S, 222 amino acids, UniProt Q16763). AlphaFold-predicted 3D structure; by default coloured by model confidence (blue = very high, orange = very low, typical of disordered regions).
E3 ubiquitin-protein ligase TRIM71 (TRIM71) — E3 ubiquitin-protein ligase TRIM71 — human protein (gene TRIM71, 868 amino acids, UniProt Q2Q1W2). AlphaFold-predicted 3D structure; by default coloured by model confidence (blue = very high, orange = very low, typical of disordered regions).
Kelch-like protein 40 (KLHL40) — Kelch-like protein 40 — human protein (gene KLHL40, 621 amino acids, UniProt Q2TBA0). AlphaFold-predicted 3D structure; by default coloured by model confidence (blue = very high, orange = very low, typical of disordered regions).
Probable E3 SUMO-protein ligase RNF212 (RNF212) — Probable E3 SUMO-protein ligase RNF212 — human protein (gene RNF212, 297 amino acids, UniProt Q495C1). AlphaFold-predicted 3D structure; by default coloured by model confidence (blue = very high, orange = very low, typical of disordered regions).
BTB/POZ domain-containing protein KCTD21 (KCTD21) — BTB/POZ domain-containing protein KCTD21 — human protein (gene KCTD21, 260 amino acids, UniProt Q4G0X4). AlphaFold-predicted 3D structure; by default coloured by model confidence (blue = very high, orange = very low, typical of disordered regions).
F-box only protein 43 (FBXO43) — F-box only protein 43 — human protein (gene FBXO43, 708 amino acids, UniProt Q4G163). AlphaFold-predicted 3D structure; by default coloured by model confidence (blue = very high, orange = very low, typical of disordered regions).
Kelch-like protein 12 (KLHL12) — Kelch-like protein 12 — human protein (gene KLHL12, 568 amino acids, UniProt Q53G59). AlphaFold-predicted 3D structure; by default coloured by model confidence (blue = very high, orange = very low, typical of disordered regions).
Ubiquitin carboxyl-terminal hydrolase 39 (USP39) — Ubiquitin carboxyl-terminal hydrolase 39 — human protein (gene USP39, 565 amino acids, UniProt Q53GS9). AlphaFold-predicted 3D structure; by default coloured by model confidence (blue = very high, orange = very low, typical of disordered regions).
Kelch-like protein 22 (KLHL22) — Kelch-like protein 22 — human protein (gene KLHL22, 634 amino acids, UniProt Q53GT1). AlphaFold-predicted 3D structure; by default coloured by model confidence (blue = very high, orange = very low, typical of disordered regions).
DDB1- and CUL4-associated factor 6 (DCAF6) — DDB1- and CUL4-associated factor 6 — human protein (gene DCAF6, 860 amino acids, UniProt Q58WW2). AlphaFold-predicted 3D structure; by default coloured by model confidence (blue = very high, orange = very low, typical of disordered regions).
Probable E3 ubiquitin-protein ligase HERC4 (HERC4) — Probable E3 ubiquitin-protein ligase HERC4 — human protein (gene HERC4, 1057 amino acids, UniProt Q5GLZ8). AlphaFold-predicted 3D structure; by default coloured by model confidence (blue = very high, orange = very low, typical of disordered regions).
DDB1- and CUL4-associated factor 17 (DCAF17) — DDB1- and CUL4-associated factor 17 — human protein (gene DCAF17, 520 amino acids, UniProt Q5H9S7). AlphaFold-predicted 3D structure; by default coloured by model confidence (blue = very high, orange = very low, typical of disordered regions).
E3 ubiquitin-protein ligase RNFT1 (RNFT1) — E3 ubiquitin-protein ligase RNFT1 — human protein (gene RNFT1, 435 amino acids, UniProt Q5M7Z0). AlphaFold-predicted 3D structure; by default coloured by model confidence (blue = very high, orange = very low, typical of disordered regions).
DDB1- and CUL4-associated factor 10 (DCAF10) — DDB1- and CUL4-associated factor 10 — human protein (gene DCAF10, 559 amino acids, UniProt Q5QP82). AlphaFold-predicted 3D structure; by default coloured by model confidence (blue = very high, orange = very low, typical of disordered regions).
E3 ubiquitin-protein ligase MARCHF8 (MARCHF8) — E3 ubiquitin-protein ligase MARCHF8 — human protein (gene MARCHF8, 291 amino acids, UniProt Q5T0T0). AlphaFold-predicted 3D structure; by default coloured by model confidence (blue = very high, orange = very low, typical of disordered regions).
E3 ubiquitin-protein ligase DCST1 (DCST1) — E3 ubiquitin-protein ligase DCST1 — human protein (gene DCST1, 706 amino acids, UniProt Q5T197). AlphaFold-predicted 3D structure; by default coloured by model confidence (blue = very high, orange = very low, typical of disordered regions).
E3 ubiquitin-protein ligase HECTD3 (HECTD3) — E3 ubiquitin-protein ligase HECTD3 — human protein (gene HECTD3, 861 amino acids, UniProt Q5T447). AlphaFold-predicted 3D structure; by default coloured by model confidence (blue = very high, orange = very low, typical of disordered regions).
DDB1- and CUL4-associated factor 12 (DCAF12) — DDB1- and CUL4-associated factor 12 — human protein (gene DCAF12, 453 amino acids, UniProt Q5T6F0). AlphaFold-predicted 3D structure; by default coloured by model confidence (blue = very high, orange = very low, typical of disordered regions).
E3 ubiquitin-protein ligase RNF187 (RNF187) — E3 ubiquitin-protein ligase RNF187 — human protein (gene RNF187, 235 amino acids, UniProt Q5TA31). AlphaFold-predicted 3D structure; by default coloured by model confidence (blue = very high, orange = very low, typical of disordered regions).
DDB1- and CUL4-associated factor 8 (DCAF8) — DDB1- and CUL4-associated factor 8 — human protein (gene DCAF8, 597 amino acids, UniProt Q5TAQ9). AlphaFold-predicted 3D structure; by default coloured by model confidence (blue = very high, orange = very low, typical of disordered regions).
RNA-binding E3 ubiquitin-protein ligase MEX3C (MEX3C) — RNA-binding E3 ubiquitin-protein ligase MEX3C — human protein (gene MEX3C, 659 amino acids, UniProt Q5U5Q3). AlphaFold-predicted 3D structure; by default coloured by model confidence (blue = very high, orange = very low, typical of disordered regions).
E3 ubiquitin-protein ligase RNF220 (RNF220) — E3 ubiquitin-protein ligase RNF220 — human protein (gene RNF220, 566 amino acids, UniProt Q5VTB9). AlphaFold-predicted 3D structure; by default coloured by model confidence (blue = very high, orange = very low, typical of disordered regions).
E3 ubiquitin-protein ligase BRE1A (RNF20) — E3 ubiquitin-protein ligase BRE1A — human protein (gene RNF20, 975 amino acids, UniProt Q5VTR2). AlphaFold-predicted 3D structure; by default coloured by model confidence (blue = very high, orange = very low, typical of disordered regions).
Ubiquitin-conjugating enzyme E2 U (UBE2U) — Ubiquitin-conjugating enzyme E2 U — human protein (gene UBE2U, 321 amino acids, UniProt Q5VVX9). AlphaFold-predicted 3D structure; by default coloured by model confidence (blue = very high, orange = very low, typical of disordered regions).
ORC ubiquitin ligase 1 (OBI1) — ORC ubiquitin ligase 1 — human protein (gene OBI1, 726 amino acids, UniProt Q5W0B1). AlphaFold-predicted 3D structure; by default coloured by model confidence (blue = very high, orange = very low, typical of disordered regions).
E3 ubiquitin-protein ligase RNF123 (RNF123) — E3 ubiquitin-protein ligase RNF123 — human protein (gene RNF123, 1314 amino acids, UniProt Q5XPI4). AlphaFold-predicted 3D structure; by default coloured by model confidence (blue = very high, orange = very low, typical of disordered regions).
F-box only protein 31 (FBXO31) — F-box only protein 31 — human protein (gene FBXO31, 539 amino acids, UniProt Q5XUX0). AlphaFold-predicted 3D structure; by default coloured by model confidence (blue = very high, orange = very low, typical of disordered regions).
DDB1- and CUL4-associated factor 15 (DCAF15) — DDB1- and CUL4-associated factor 15 — human protein (gene DCAF15, 600 amino acids, UniProt Q66K64). AlphaFold-predicted 3D structure; by default coloured by model confidence (blue = very high, orange = very low, typical of disordered regions).
Transcription factor E4F1 (E4F1) — Transcription factor E4F1 — human protein (gene E4F1, 784 amino acids, UniProt Q66K89). AlphaFold-predicted 3D structure; by default coloured by model confidence (blue = very high, orange = very low, typical of disordered regions).
E3 ubiquitin-protein ligase RNF43 (RNF43) — E3 ubiquitin-protein ligase RNF43 — human protein (gene RNF43, 783 amino acids, UniProt Q68DV7). AlphaFold-predicted 3D structure; by default coloured by model confidence (blue = very high, orange = very low, typical of disordered regions).
BTB/POZ domain-containing protein KCTD11 (KCTD11) — BTB/POZ domain-containing protein KCTD11 — human protein (gene KCTD11, 232 amino acids, UniProt Q693B1). AlphaFold-predicted 3D structure; by default coloured by model confidence (blue = very high, orange = very low, typical of disordered regions).
E3 ubiquitin-protein ligase TRIM68 (TRIM68) — E3 ubiquitin-protein ligase TRIM68 — human protein (gene TRIM68, 485 amino acids, UniProt Q6AZZ1). AlphaFold-predicted 3D structure; by default coloured by model confidence (blue = very high, orange = very low, typical of disordered regions).
Small ubiquitin-related modifier 4 (SUMO4) — Small ubiquitin-related modifier 4 — human protein (gene SUMO4, 95 amino acids, UniProt Q6EEV6). AlphaFold-predicted 3D structure; by default coloured by model confidence (blue = very high, orange = very low, typical of disordered regions).
Speckle-type POZ protein-like (SPOPL) — Speckle-type POZ protein-like — human protein (gene SPOPL, 392 amino acids, UniProt Q6IQ16). AlphaFold-predicted 3D structure; by default coloured by model confidence (blue = very high, orange = very low, typical of disordered regions).
F-box and leucine-rich protein 22 (FBXL22) — F-box and leucine-rich protein 22 — human protein (gene FBXL22, 231 amino acids, UniProt Q6P050). AlphaFold-predicted 3D structure; by default coloured by model confidence (blue = very high, orange = very low, typical of disordered regions).
F-box only protein 42 (FBXO42) — F-box only protein 42 — human protein (gene FBXO42, 717 amino acids, UniProt Q6P3S6). AlphaFold-predicted 3D structure; by default coloured by model confidence (blue = very high, orange = very low, typical of disordered regions).
E3 ubiquitin ligase TRIM40 (TRIM40) — E3 ubiquitin ligase TRIM40 — human protein (gene TRIM40, 258 amino acids, UniProt Q6P9F5). AlphaFold-predicted 3D structure; by default coloured by model confidence (blue = very high, orange = very low, typical of disordered regions).
E3 ubiquitin-protein ligase RFWD3 (RFWD3) — E3 ubiquitin-protein ligase RFWD3 — human protein (gene RFWD3, 774 amino acids, UniProt Q6PCD5). AlphaFold-predicted 3D structure; by default coloured by model confidence (blue = very high, orange = very low, typical of disordered regions).
F-box/LRR-repeat protein 19 (FBXL19) — F-box/LRR-repeat protein 19 — human protein (gene FBXL19, 694 amino acids, UniProt Q6PCT2). AlphaFold-predicted 3D structure; by default coloured by model confidence (blue = very high, orange = very low, typical of disordered regions).
DCN1-like protein 2 (DCUN1D2) — DCN1-like protein 2 — human protein (gene DCUN1D2, 259 amino acids, UniProt Q6PH85). AlphaFold-predicted 3D structure; by default coloured by model confidence (blue = very high, orange = very low, typical of disordered regions).
Kelch domain-containing protein 10 (KLHDC10) — Kelch domain-containing protein 10 — human protein (gene KLHDC10, 442 amino acids, UniProt Q6PID8). AlphaFold-predicted 3D structure; by default coloured by model confidence (blue = very high, orange = very low, typical of disordered regions).
F-box only protein 38 (FBXO38) — F-box only protein 38 — human protein (gene FBXO38, 1188 amino acids, UniProt Q6PIJ6). AlphaFold-predicted 3D structure; by default coloured by model confidence (blue = very high, orange = very low, typical of disordered regions).
SPRY domain-containing SOCS box protein 3 (SPSB3) — SPRY domain-containing SOCS box protein 3 — human protein (gene SPSB3, 355 amino acids, UniProt Q6PJ21). AlphaFold-predicted 3D structure; by default coloured by model confidence (blue = very high, orange = very low, typical of disordered regions).
F-box only protein 46 (FBXO46) — F-box only protein 46 — human protein (gene FBXO46, 603 amino acids, UniProt Q6PJ61). AlphaFold-predicted 3D structure; by default coloured by model confidence (blue = very high, orange = very low, typical of disordered regions).
E3 ubiquitin-protein ligase TRAF7 (TRAF7) — E3 ubiquitin-protein ligase TRAF7 — human protein (gene TRAF7, 670 amino acids, UniProt Q6Q0C0). AlphaFold-predicted 3D structure; by default coloured by model confidence (blue = very high, orange = very low, typical of disordered regions).
Kelch-like protein 24 (KLHL24) — Kelch-like protein 24 — human protein (gene KLHL24, 600 amino acids, UniProt Q6TFL4). AlphaFold-predicted 3D structure; by default coloured by model confidence (blue = very high, orange = very low, typical of disordered regions).
E3 ubiquitin-protein ligase LRSAM1 (LRSAM1) — E3 ubiquitin-protein ligase LRSAM1 — human protein (gene LRSAM1, 723 amino acids, UniProt Q6UWE0). AlphaFold-predicted 3D structure; by default coloured by model confidence (blue = very high, orange = very low, typical of disordered regions).
E3 ubiquitin-protein ligase NHLRC1 (NHLRC1) — E3 ubiquitin-protein ligase NHLRC1 — human protein (gene NHLRC1, 395 amino acids, UniProt Q6VVB1). AlphaFold-predicted 3D structure; by default coloured by model confidence (blue = very high, orange = very low, typical of disordered regions).
F-box/WD repeat-containing protein 12 (FBXW12) — F-box/WD repeat-containing protein 12 — human protein (gene FBXW12, 464 amino acids, UniProt Q6X9E4). AlphaFold-predicted 3D structure; by default coloured by model confidence (blue = very high, orange = very low, typical of disordered regions).
Tripartite motif-containing protein 72 (TRIM72) — Tripartite motif-containing protein 72 — human protein (gene TRIM72, 477 amino acids, UniProt Q6ZMU5). AlphaFold-predicted 3D structure; by default coloured by model confidence (blue = very high, orange = very low, typical of disordered regions).
E3 ubiquitin-protein ligase RNF19B (RNF19B) — E3 ubiquitin-protein ligase RNF19B — human protein (gene RNF19B, 732 amino acids, UniProt Q6ZMZ0). AlphaFold-predicted 3D structure; by default coloured by model confidence (blue = very high, orange = very low, typical of disordered regions).
E3 ubiquitin-protein ligase Arkadia (RNF111) — E3 ubiquitin-protein ligase Arkadia — human protein (gene RNF111, 994 amino acids, UniProt Q6ZNA4). AlphaFold-predicted 3D structure; by default coloured by model confidence (blue = very high, orange = very low, typical of disordered regions).
E3 ubiquitin-protein ligase ARK2C (ARK2C) — E3 ubiquitin-protein ligase ARK2C — human protein (gene ARK2C, 346 amino acids, UniProt Q6ZSG1). AlphaFold-predicted 3D structure; by default coloured by model confidence (blue = very high, orange = very low, typical of disordered regions).
E3 ubiquitin-protein ligase UBR3 (UBR3) — E3 ubiquitin-protein ligase UBR3 — human protein (gene UBR3, 1888 amino acids, UniProt Q6ZT12). AlphaFold-predicted 3D structure; by default coloured by model confidence (blue = very high, orange = very low, typical of disordered regions).
Ubiquitin carboxyl-terminal hydrolase 49 (USP49) — Ubiquitin carboxyl-terminal hydrolase 49 — human protein (gene USP49, 688 amino acids, UniProt Q70CQ1). AlphaFold-predicted 3D structure; by default coloured by model confidence (blue = very high, orange = very low, typical of disordered regions).
Ubiquitin carboxyl-terminal hydrolase 30 (USP30) — Ubiquitin carboxyl-terminal hydrolase 30 — human protein (gene USP30, 517 amino acids, UniProt Q70CQ3). AlphaFold-predicted 3D structure; by default coloured by model confidence (blue = very high, orange = very low, typical of disordered regions).
Ubiquitin carboxyl-terminal hydrolase 31 (USP31) — Ubiquitin carboxyl-terminal hydrolase 31 — human protein (gene USP31, 1352 amino acids, UniProt Q70CQ4). AlphaFold-predicted 3D structure; by default coloured by model confidence (blue = very high, orange = very low, typical of disordered regions).
Ubiquitin carboxyl-terminal hydrolase 53 (USP53) — Ubiquitin carboxyl-terminal hydrolase 53 — human protein (gene USP53, 1073 amino acids, UniProt Q70EK8). AlphaFold-predicted 3D structure; by default coloured by model confidence (blue = very high, orange = very low, typical of disordered regions).
Ubiquitin carboxyl-terminal hydrolase 51 (USP51) — Ubiquitin carboxyl-terminal hydrolase 51 — human protein (gene USP51, 711 amino acids, UniProt Q70EK9). AlphaFold-predicted 3D structure; by default coloured by model confidence (blue = very high, orange = very low, typical of disordered regions).
Ubiquitin carboxyl-terminal hydrolase 54 (USP54) — Ubiquitin carboxyl-terminal hydrolase 54 — human protein (gene USP54, 1684 amino acids, UniProt Q70EL1). AlphaFold-predicted 3D structure; by default coloured by model confidence (blue = very high, orange = very low, typical of disordered regions).
Ubiquitin carboxyl-terminal hydrolase 45 (USP45) — Ubiquitin carboxyl-terminal hydrolase 45 — human protein (gene USP45, 814 amino acids, UniProt Q70EL2). AlphaFold-predicted 3D structure; by default coloured by model confidence (blue = very high, orange = very low, typical of disordered regions).
Ubiquitin carboxyl-terminal hydrolase 43 (USP43) — Ubiquitin carboxyl-terminal hydrolase 43 — human protein (gene USP43, 1123 amino acids, UniProt Q70EL4). AlphaFold-predicted 3D structure; by default coloured by model confidence (blue = very high, orange = very low, typical of disordered regions).
Ubiquitin-conjugating enzyme E2 R2 (UBE2R2) — Ubiquitin-conjugating enzyme E2 R2 — human protein (gene UBE2R2, 238 amino acids, UniProt Q712K3). AlphaFold-predicted 3D structure; by default coloured by model confidence (blue = very high, orange = very low, typical of disordered regions).