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Membrane proteins & channels (PDB): 101 3D models

DNA, RNA, nucleic-acid drugs, gene editing, proteins and 300+ real PDB structures (real sizes 1–100 nm). Each one is a ready-made 3D model you can turn, recolour and place in a figure — open BioDioRama and type its name in the Library search.

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V-ATPase (yeast) — Yeast v-atpase state 2 — cryo-EM structure, 2015 (PDB 3J9U), downloaded from the RCSB Protein Data Bank.
Aquaporin-1 — Crystal structure of the aqp1 water channel — X-ray structure, 2002 (PDB 1J4N), downloaded from the RCSB Protein Data Bank.
Aquaporin Z — 2.5 angstrom resolution x-ray structure of aquaporin z — X-ray structure, 2003 (PDB 1RC2), downloaded from the RCSB Protein Data Bank.
KcsA potassium channel — Potassium channel (kcsa) from streptomyces lividans — X-ray structure, 1998 (PDB 1BL8), downloaded from the RCSB Protein Data Bank.
Kv1.2 potassium channel — Mammalian shaker kv1.2 potassium channel- beta subunit complex — X-ray structure, 2005 (PDB 2A79), downloaded from the RCSB Protein Data Bank.
Nicotinic acetylcholine receptor — Refined structure of the nicotinic acetylcholine receptor at 4a resolution. — cryo-EM structure, 2005 (PDB 2BG9), downloaded from the RCSB Protein Data Bank.
P-glycoprotein (drug efflux pump) — Corrected structure of mouse p-glycoprotein — X-ray structure, 2013 (PDB 4M1M), downloaded from the RCSB Protein Data Bank.
MsbA ABC transporter — Crystal structure of msba from salmonella typhimurium with amppnp, higher resolution form — X-ray structure, 2007 (PDB 3B60), downloaded from the RCSB Protein Data Bank.
SERCA calcium pump — Crystal structure of calcium atpase with two bound calcium ions — X-ray structure, 2004 (PDB 1SU4), downloaded from the RCSB Protein Data Bank.
Glucose transporter GLUT1 — Crystal structure of the human glucose transporter glut1 — X-ray structure, 2014 (PDB 4PYP), downloaded from the RCSB Protein Data Bank.
CFTR — Dephosphorylated, atp-free human cystic fibrosis transmembrane conductance regulator (cftr) — cryo-EM structure, 2017 (PDB 5UAK), downloaded from the RCSB Protein Data Bank.
OmpF porin — Ompf porin — X-ray structure, 1995 (PDB 2OMF), downloaded from the RCSB Protein Data Bank.
MscL mechanosensitive channel — Mechanosensitive channel of large conductance (mscl) — X-ray structure, 2007 (PDB 2OAR), downloaded from the RCSB Protein Data Bank.
Connexin-26 gap junction — Structure of the connexin-26 gap junction channel at 3.5 angstrom resolution — X-ray structure, 2009 (PDB 2ZW3), downloaded from the RCSB Protein Data Bank.
α-Hemolysin pore — Alpha-hemolysin from staphylococcus aureus — X-ray structure, 1998 (PDB 7AHL), downloaded from the RCSB Protein Data Bank.
AMPA receptor — Ampa subtype ionotropic glutamate receptor in complex with competitive antagonist zk 200775 — X-ray structure, 2009 (PDB 3KG2), downloaded from the RCSB Protein Data Bank.
NMDA receptor — Crystal structure of glun1a/glun2b nmda receptor ion channel — X-ray structure, 2014 (PDB 4PE5), downloaded from the RCSB Protein Data Bank.
Dopamine transporter — X-ray structure of dopamine transporter elucidates antidepressant mechanism — X-ray structure, 2013 (PDB 4M48), downloaded from the RCSB Protein Data Bank.
Serotonin transporter — X-ray structure of the ts3 human serotonin transporter complexed with paroxetine at the central site — X-ray structure, 2016 (PDB 5I6X), downloaded from the RCSB Protein Data Bank.
Bacteriorhodopsin — Bacteriorhodopsin/lipid complex at 1.55 a resolution — X-ray structure, 1999 (PDB 1C3W), downloaded from the RCSB Protein Data Bank.
Photosystem II — Crystal structure analysis of photosystem ii complex — X-ray structure, 2014 (PDB 3WU2), downloaded from the RCSB Protein Data Bank.
Photosystem I — Crystal structure of photosystem i: a photosynthetic reaction center and core antenna system from cyanobacteria — X-ray structure, 2001 (PDB 1JB0), downloaded from the RCSB Protein Data Bank.
Light-harvesting complex II — Crystal structure of spinach major light-harvesting complex at 2.72 angstrom resolution — X-ray structure, 2004 (PDB 1RWT), downloaded from the RCSB Protein Data Bank.
Na+/K+-ATPase — Crystal structure of the sodium - potassium pump in the e2.2k+.pi state — X-ray structure, 2009 (PDB 2ZXE), downloaded from the RCSB Protein Data Bank.
ADP/ATP carrier — structure of mitochondrial adp/atp carrier in complex with carboxyatractyloside — X-ray structure, 2003 (PDB 1OKC), downloaded from the RCSB Protein Data Bank.
TRPV1 — Structure of trpv1 ion channel determined by single particle electron cryo-microscopy — cryo-EM structure, 2013 (PDB 3J5P), downloaded from the RCSB Protein Data Bank.
TRPV1 with capsaicin — Structure of trpv1 determined in lipid nanodisc — cryo-EM structure, 2016 (PDB 5IRZ), downloaded from the RCSB Protein Data Bank.
Acid-sensing ion channel ASIC1 — Structure of an acid-sensing ion channel 1 at 1.9 a resolution and low ph — X-ray structure, 2007 (PDB 2QTS), downloaded from the RCSB Protein Data Bank.
Serotonin 5-HT3 receptor — X-ray structure of the mouse serotonin 5-ht3 receptor — X-ray structure, 2014 (PDB 4PIR), downloaded from the RCSB Protein Data Bank.
GABA-A receptor (β3 pentamer) — Crystal structure of a human gamma-aminobutyric acid receptor, the gaba(a)r-beta3 homopentamer — X-ray structure, 2014 (PDB 4COF), downloaded from the RCSB Protein Data Bank.
GABA-A receptor with diazepam — Cryoem structure of human full-length alpha1beta3gamma2l gaba(a)r in complex with diazepam (valium), gaba and megabody mb38. — cryo-EM structure, 2019 (PDB 6HUP), downloaded from the RCSB Protein Data Bank.
Nicotinic receptor (human α4β2) — X-ray structure of the human alpha4beta2 nicotinic receptor — X-ray structure, 2016 (PDB 5KXI), downloaded from the RCSB Protein Data Bank.
Nicotinic receptor — Structure of the 2alpha3beta stiochiometry of the human alpha4beta2 nicotinic receptor — cryo-EM structure, 2018 (PDB 6CNJ), downloaded from the RCSB Protein Data Bank.
Ryanodine receptor RyR1 — Structure of ryr1 in a closed state (c1 conformer) — cryo-EM structure, 2016 (PDB 5GKY), downloaded from the RCSB Protein Data Bank.
Nav1.7 — Human nav1.7-vsd4-navab in complex with gx-936. — X-ray structure, 2015 (PDB 5EK0), downloaded from the RCSB Protein Data Bank.
Nav1.2 — Human nav1.2-beta2-kiiia ternary complex — cryo-EM structure, 2019 (PDB 6J8E), downloaded from the RCSB Protein Data Bank.
Sodium channel Nav1.4–β1 — Structure of the nav1.4-beta1 complex from electric eel — cryo-EM structure, 2017 (PDB 5XSY), downloaded from the RCSB Protein Data Bank.
NavAb — Crystal structure of the navab voltage-gated sodium channel (ile217cys, 2.7 a) — X-ray structure, 2011 (PDB 3RVY), downloaded from the RCSB Protein Data Bank.
Insect sodium channel NavPaS — Complex of voltage-gated sodium channel navpas from american cockroach periplaneta americana bound with tetrodotoxin and dc1a — cryo-EM structure, 2018 (PDB 6A95), downloaded from the RCSB Protein Data Bank.
Cav1.1 — Structure of the mammalian voltage-gated calcium channel cav1.1 complex at near atomic resolution — cryo-EM structure, 2016 (PDB 5GJV), downloaded from the RCSB Protein Data Bank.
KcsA (high resolution) — Potassium channel kcsa-fab complex in high concentration of k+ — X-ray structure, 2001 (PDB 1K4C), downloaded from the RCSB Protein Data Bank.
Kv1.2 paddle — Shaker family voltage dependent potassium channel (kv1.2-kv2.1 paddle chimera channel) in association with beta subunit — X-ray structure, 2007 (PDB 2R9R), downloaded from the RCSB Protein Data Bank.
KCNQ1 potassium channel — Cryoem structure of xenopus kcnq1 channel — cryo-EM structure, 2017 (PDB 5VMS), downloaded from the RCSB Protein Data Bank.
hERG potassium channel — Cryo-em structure of the human ether-a-go-go related k+ channel — cryo-EM structure, 2017 (PDB 5VA1), downloaded from the RCSB Protein Data Bank.
EmrE — Emre multidrug transporter in complex with tpp, c2 crystal form — X-ray structure, 2007 (PDB 3B5D), downloaded from the RCSB Protein Data Bank.
EmrD — Structure of the multidrug transporter emrd from escherichia coli — X-ray structure, 2006 (PDB 2GFP), downloaded from the RCSB Protein Data Bank.
Lactose permease (LacY) — Crystal structure of lactose permease — X-ray structure, 2003 (PDB 1PV6), downloaded from the RCSB Protein Data Bank.
Glycerol-3-phosphate transporter — Crystal structure of the glycerol-3-phosphate transporter from e.coli — X-ray structure, 2003 (PDB 1PW4), downloaded from the RCSB Protein Data Bank.
Glutamate transporter GltPh — Crystal structure of gltph in complex with l-asp — X-ray structure, 2007 (PDB 2NWL), downloaded from the RCSB Protein Data Bank.
P-glycoprotein with taxol — Nanodisc reconstituted human abcb1 in complex with uic2 fab and taxol — cryo-EM structure, 2019 (PDB 6QEX), downloaded from the RCSB Protein Data Bank.
Multidrug resistance protein MRP1 — Cryo-em structure of bovine multidrug resistance protein 1 (mrp1) — cryo-EM structure, 2017 (PDB 5UJ9), downloaded from the RCSB Protein Data Bank.
CFTR (phosphorylated) — Phosphorylated, atp-bound human cystic fibrosis transmembrane conductance regulator (cftr) — cryo-EM structure, 2018 (PDB 6MSM), downloaded from the RCSB Protein Data Bank.
BtuB–TonB complex — Structure of the btub:tonb complex — X-ray structure, 2006 (PDB 2GSK), downloaded from the RCSB Protein Data Bank.
GLUT3 — Crystal structure of human glut3 bound to d-glucose in the outward-occluded conformation at 1.5 angstrom — X-ray structure, 2015 (PDB 4ZW9), downloaded from the RCSB Protein Data Bank.
XylE — The structure of the mfs (major facilitator superfamily) proton:xylose symporter xyle bound to d-xylose — X-ray structure, 2012 (PDB 4GBY), downloaded from the RCSB Protein Data Bank.
SERCA — Structure of the e2 beryllium fluoride complex of the serca ca2+-atpase — X-ray structure, 2007 (PDB 3B9B), downloaded from the RCSB Protein Data Bank.
Sodium–potassium pump — Crystal structure of the sodium-potassium pump — X-ray structure, 2010 (PDB 3KDP), downloaded from the RCSB Protein Data Bank.
Na+/K+-ATPase — Crystal structure of na+,k+-atpase in the na+-bound state — X-ray structure, 2013 (PDB 4HQJ), downloaded from the RCSB Protein Data Bank.
Proton pump (V-ATPase) — Cryo-em structure of a p-type atpase — cryo-EM structure, 2018 (PDB 6A69), downloaded from the RCSB Protein Data Bank.
V-ATPase — Yeast v-atpase in complex with legionella pneumophila effector sidk (rotational state 1) — cryo-EM structure, 2017 (PDB 5VOX), downloaded from the RCSB Protein Data Bank.
V-ATPase — Human v-atpase in state 1 with sidk and adp — cryo-EM structure, 2020 (PDB 6WM2), downloaded from the RCSB Protein Data Bank.
ATP synthase — Autoinhibited e. coli atp synthase state 1 — cryo-EM structure, 2016 (PDB 5T4O), downloaded from the RCSB Protein Data Bank.
ATP synthase (bovine) — Bovine mitochondrial atp synthase state 1a — cryo-EM structure, 2015 (PDB 5ARA), downloaded from the RCSB Protein Data Bank.
ATP synthase — Cryo-em structure of the mammalian dp-state atp synthase — cryo-EM structure, 2019 (PDB 6J5I), downloaded from the RCSB Protein Data Bank.
ATP synthase c-ring — A1c12 subcomplex of f1fo atp synthase — NMR structure, 1999 (PDB 1C17), downloaded from the RCSB Protein Data Bank.
ATP synthase F1–c10 — Molecular architecture of the rotary motor in atp synthase from yeast mitochondria — X-ray structure, 1999 (PDB 1QO1), downloaded from the RCSB Protein Data Bank.
Human respiratory complex I — Cryo-em structure of human respiratory complex i — cryo-EM structure, 2017 (PDB 5XTD), downloaded from the RCSB Protein Data Bank.
Cytochrome bc1 complex — Cytochrome bc1 complex from bovine — X-ray structure, 1999 (PDB 1BE3), downloaded from the RCSB Protein Data Bank.
Cytochrome bc1 — Cytochrome bc1 complex from chicken — X-ray structure, 1998 (PDB 1BCC), downloaded from the RCSB Protein Data Bank.
Cytochrome c oxidase — Bovine heart cytochrome c oxidase at the fully oxidized state — X-ray structure, 1999 (PDB 2OCC), downloaded from the RCSB Protein Data Bank.
Supercomplex — Cryo-em structure of human respiratory supercomplex i1iii2iv1 — cryo-EM structure, 2017 (PDB 5XTH), downloaded from the RCSB Protein Data Bank.
Photosystem II — Crystal structure of photosystem ii from thermosynechococcus elongatus — X-ray structure, 2005 (PDB 2AXT), downloaded from the RCSB Protein Data Bank.
Photosynthetic reaction centre — Crystallographic refinement at 2.3 angstroms resolution and refined model of the photosynthetic reaction center from rhodopseudomonas vir… — X-ray structure, 1989 (PDB 1PRC), downloaded from the RCSB Protein Data Bank.
Photosynthetic reaction centre — Crystal structure of photosynthetic reaction center from a thermophilic bacterium, thermochromatium tepidum — X-ray structure, 2000 (PDB 1EYS), downloaded from the RCSB Protein Data Bank.
LH2 light-harvesting complex — Integral membrane peripheral light harvesting complex from rhodopseudomonas acidophila strain 10050 — X-ray structure, 1997 (PDB 1KZU), downloaded from the RCSB Protein Data Bank.
Sav1866 ABC — Multidrug abc transporter sav1866 — X-ray structure, 2006 (PDB 2HYD), downloaded from the RCSB Protein Data Bank.
BtuCD vitamin B12 ABC transporter — Bacterial abc transporter involved in b12 uptake — X-ray structure, 2002 (PDB 1L7V), downloaded from the RCSB Protein Data Bank.
ABC transporter — Crystal structure of the resting state maltose transporter from e. coli — X-ray structure, 2009 (PDB 3FH6), downloaded from the RCSB Protein Data Bank.
ADP/ATP carrier — The bovine mitochondrial adp-atp carrier — X-ray structure, 2005 (PDB 2C3E), downloaded from the RCSB Protein Data Bank.
TolC — 2.1a x-ray structure of tolc: an integral outer membrane protein and efflux pump component from escherichia coli — X-ray structure, 2000 (PDB 1EK9), downloaded from the RCSB Protein Data Bank.
PapC pilus usher pore — Structure of the p pilus usher (papc) translocation pore — X-ray structure, 2008 (PDB 2VQI), downloaded from the RCSB Protein Data Bank.
OmpA — Outer membrane protein a (ompa) transmembrane domain — X-ray structure, 1998 (PDB 1BXW), downloaded from the RCSB Protein Data Bank.
OmpX — Crystal structure of the outer membrane protein ompx from escherichia coli — X-ray structure, 1999 (PDB 1QJ8), downloaded from the RCSB Protein Data Bank.
Porin — Structure of porin refined at 1.8 angstroms resolution — X-ray structure, 1993 (PDB 2POR), downloaded from the RCSB Protein Data Bank.
Porin — Refined structure of porin from rhodopseudomonas blastica and comparison with the porin from rhodobacter capsulatus — X-ray structure, 1994 (PDB 1PRN), downloaded from the RCSB Protein Data Bank.
FhuA — Fhua from e. coli — X-ray structure, 1999 (PDB 1BY3), downloaded from the RCSB Protein Data Bank.
FecA outer-membrane transporter — Crystal structure of the outer membrane transporter feca — X-ray structure, 2002 (PDB 1KMO), downloaded from the RCSB Protein Data Bank.
FimD usher with FimC–FimH — Crystal structure of the fimd usher bound to its cognate fimc:fimh substrate — X-ray structure, 2011 (PDB 3RFZ), downloaded from the RCSB Protein Data Bank.
EspP autotransporter — The crystal structure of the e.coli espp autotransporter beta-domain. — X-ray structure, 2007 (PDB 2QOM), downloaded from the RCSB Protein Data Bank.
TamA outer-membrane protein — Crystal structure of tama from e. coli — X-ray structure, 2013 (PDB 4C00), downloaded from the RCSB Protein Data Bank.
MscS — Mechanosensitive channel of small conductance (mscs) — X-ray structure, 2007 (PDB 2OAU), downloaded from the RCSB Protein Data Bank.
MthK potassium channel pore — High resolution open mthk pore structure crystallized in 100 mm k+ — X-ray structure, 2010 (PDB 3LDC), downloaded from the RCSB Protein Data Bank.
TMEM16 lipid scramblase — Crystal structure of the lipid scramblase nhtmem16 in crystal form 1 — X-ray structure, 2014 (PDB 4WIS), downloaded from the RCSB Protein Data Bank.
Piezo1 — Structure of the mechanosensitive piezo1 channel — cryo-EM structure, 2018 (PDB 5Z10), downloaded from the RCSB Protein Data Bank.
Piezo1 — Structure of the mechanosensitive channel piezo1 — cryo-EM structure, 2017 (PDB 6B3R), downloaded from the RCSB Protein Data Bank.
Piezo1 mechanosensitive channel — Structure of the mechanically activated ion channel piezo1 — cryo-EM structure, 2017 (PDB 6BPZ), downloaded from the RCSB Protein Data Bank.
AMPA receptor GluA2 (active) — Activated glua2 complex bound to glutamate, cyclothiazide, and stz in digitonin — cryo-EM structure, 2017 (PDB 5WEO), downloaded from the RCSB Protein Data Bank.
Gasdermin pore — Cryo-em structure of the gasdermin a3 membrane pore — cryo-EM structure, 2018 (PDB 6CB8), downloaded from the RCSB Protein Data Bank.
Gasdermin D pore — Gasdermin d pore — cryo-EM structure, 2021 (PDB 6VFE), downloaded from the RCSB Protein Data Bank.
Type III secretion needle complex — Three-dimensional model of salmonella's needle complex at subnanometer resolution — cryo-EM structure, 2011 (PDB 2Y9J), downloaded from the RCSB Protein Data Bank.
Perforin — The x-ray crystal structure of lymphocyte perforin — X-ray structure, 2010 (PDB 3NSJ), downloaded from the RCSB Protein Data Bank.