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Neuroscience proteins (PDB): 72 3D models

DNA, RNA, nucleic-acid drugs, gene editing, proteins and 300+ real PDB structures (real sizes 1–100 nm). Each one is a ready-made 3D model you can turn, recolour and place in a figure — open BioDioRama and type its name in the Library search.

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Synaptotagmin-1 with SV2A peptide phosphorylated at Thr84 — Structure of synaptotagmin-1 with sv2a peptide phosphorylated at thr84 — X-ray structure, 2015 (PDB 4V11), downloaded from the RCSB Protein Data Bank.
Munc13-1 MUN domain — Crystal structure of munc13-1 mun domain — X-ray structure, 2015 (PDB 4Y21), downloaded from the RCSB Protein Data Bank.
The RIM1alpha C2B domain — The rim1alpha c2b domain — X-ray structure, 2007 (PDB 2Q3X), downloaded from the RCSB Protein Data Bank.
Synaptotagmin I C2A domain with Cu(II) (3F01) — Crystal structure of synaptotagmin i c2a domain with cu(ii) — X-ray structure, 2009 (PDB 3F01), downloaded from the RCSB Protein Data Bank.
Synaptotagmin I C2A domain — Crystal structure of synaptotagmin i c2a domain — X-ray structure, 2009 (PDB 3F04), downloaded from the RCSB Protein Data Bank.
Synaptotagmin I C2A domain with Mn(II) — Crystal structure of synaptotagmin i c2a domain with mn(ii) — X-ray structure, 2009 (PDB 3F05), downloaded from the RCSB Protein Data Bank.
Synaptotagmin I C2A domain with Cu(II) (3F00) — Crystal structure of synaptotagmin i c2a domain with cu(ii) — X-ray structure, 2009 (PDB 3F00), downloaded from the RCSB Protein Data Bank.
SM Protein Vps45 in Complex with Qa SNARE Tlg2 — Sm protein vps45 in complex with qa snare tlg2 — X-ray structure, 2020 (PDB 6XM1), downloaded from the RCSB Protein Data Bank.
Neuronal complexin/snare complex from the squid loligo pealei — X-ray structure of the neuronal complexin/snare complex from the squid loligo pealei — X-ray structure, 2002 (PDB 1L4A), downloaded from the RCSB Protein Data Bank.
Yeast plasma membrane SNARE complex — Structure of the yeast plasma membrane snare complex — X-ray structure, 2007 (PDB 3B5N), downloaded from the RCSB Protein Data Bank.
Autophagic STX17/SNAP29/VAMP8 SNARE complex — Crystal structure of the autophagic stx17/snap29/vamp8 snare complex — X-ray structure, 2020 (PDB 7BV6), downloaded from the RCSB Protein Data Bank.
Habc domain of neuronal syntaxin from the squid Loligo pealei — Crystal structure of the habc domain of neuronal syntaxin from the squid loligo pealei — X-ray structure, 2004 (PDB 1S94), downloaded from the RCSB Protein Data Bank.
Early Endosomal SNARE Complex — Crystal structure of the early endosomal snare complex — X-ray structure, 2006 (PDB 2NPS), downloaded from the RCSB Protein Data Bank.
Yeast t-snare protein SSO1 — Crystal structure of yeast t-snare protein sso1 — X-ray structure, 2000 (PDB 1FIO), downloaded from the RCSB Protein Data Bank.
Complex Between the SNARE Vam3 and the HOPS Vps33-Vps16 subcomplex… — Crystal structure of a complex between the snare vam3 and the hops vps33-vps16 subcomplex from chaetomium thermophilum — X-ray structure, 2015 (PDB 5BUZ), downloaded from the RCSB Protein Data Bank.
Amyloid-fibril forming peptide GGVVIA derived from the Alzheimer's… — Crystal structure of the amyloid-fibril forming peptide ggvvia derived from the alzheimer's amyloid abeta (abeta37-42). — X-ray structure, 2007 (PDB 2ONV), downloaded from the RCSB Protein Data Bank.
Amyloid-like IYQYGG segment from the R1 repeat of the E. coli… — Crystal structure of the amyloid-like iyqygg segment from the r1 repeat of the e. coli biofilm-associated csga curli protein — X-ray structure, 2019 (PDB 6G8C), downloaded from the RCSB Protein Data Bank.
Amyloid-like VTQVGF segment from the R5 repeat of the E. coli… — Crystal structure of the amyloid-like vtqvgf segment from the r5 repeat of the e. coli biofilm-associated csga curli protein — X-ray structure, 2019 (PDB 6G8E), downloaded from the RCSB Protein Data Bank.
Molecular basis for amyloid fibril formation and stability — Molecular basis for amyloid fibril formation and stability — X-ray structure, 2005 (PDB 2BFI), downloaded from the RCSB Protein Data Bank.
40-Residue Arctic (E22G) Beta-Amyloid Fibril Derived by Co-Analysis… — Cryoem structure of 40-residue arctic (e22g) beta-amyloid fibril derived by co-analysis with solid-state nmr | e22g abeta40 — Cryo-EM structure, 2024 (PDB 8J47), downloaded from the RCSB Protein Data Bank.
The L1 amyloid-beta(1-40)fibril in the presence of anle138b… (9RAW) — The l1 amyloid-beta(1-40)fibril in the presence of anle138b (post-treatment) — Cryo-EM structure, 2025 (PDB 9RAW), downloaded from the RCSB Protein Data Bank.
Filament of D-TLKIVWS, a D-peptide that disaggregates Alzheimer's… — Filament of d-tlkivws, a d-peptide that disaggregates alzheimer's paired helical filaments, determined by cryo-em — Cryo-EM structure, 2025 (PDB 9B4J), downloaded from the RCSB Protein Data Bank.
Tau filament (9TZX) — Cryo-em structure of a tau filament — Cryo-EM structure, 2026 (PDB 9TZX), downloaded from the RCSB Protein Data Bank.
Straight tau filament extracted from PrP-CAA Patient brain tissue |… — Straight tau filament extracted from prp-caa patient brain tissue | tau filament | sf tau — Cryo-EM structure, 2021 (PDB 7MKG), downloaded from the RCSB Protein Data Bank.
Paired helical tau filament extracted from GSS Patient brain tissue… — Paired helical tau filament extracted from gss patient brain tissue | tau filament from gerstmann straussler scheinker disease | phf tau — Cryo-EM structure, 2021 (PDB 7MKH), downloaded from the RCSB Protein Data Bank.
CTE Type I tau filament from the brain of a football player — Cte type i tau filament from the brain of a football player — Cryo-EM structure, 2026 (PDB 9R88), downloaded from the RCSB Protein Data Bank.
CTE Type II tau filament from the brain of a football player — Cte type ii tau filament from the brain of a football player — Cryo-EM structure, 2026 (PDB 9R89), downloaded from the RCSB Protein Data Bank.
Enantiomer of a macrocyclic peptide containing fragments from alpha… — Crystal structure of the enantiomer of a macrocyclic peptide containing fragments from alpha synuclein 36-55 — X-ray structure, 2016 (PDB 5F1W), downloaded from the RCSB Protein Data Bank.
Macrocyclic peptide containing fragments from alpha-synuclein 36-55 — Crystal structure of a macrocyclic peptide containing fragments from alpha-synuclein 36-55. — X-ray structure, 2016 (PDB 5F1T), downloaded from the RCSB Protein Data Bank.
Recombinantly assembled E83Q alpha-synuclein fibrils — Structure of recombinantly assembled e83q alpha-synuclein fibrils — Cryo-EM structure, 2026 (PDB 9TPT), downloaded from the RCSB Protein Data Bank.
Cryo EM structure of the type 3B polymorph of alpha-synuclein at low pH — Cryo em structure of the type 3b polymorph of alpha-synuclein at low ph. — Cryo-EM structure, 2024 (PDB 9FYP), downloaded from the RCSB Protein Data Bank.
BTA-2-bound E46K alpha-synuclein fibrils — Bta-2-bound e46k alpha-synuclein fibrils — Cryo-EM structure, 2024 (PDB 8ZLI), downloaded from the RCSB Protein Data Bank.
In vitro grown G14R Alpha-Synuclein Fibrils — In vitro grown g14r alpha-synuclein fibrils — Cryo-EM structure, 2025 (PDB 9HGS), downloaded from the RCSB Protein Data Bank.
Wild-type Rabbit PrP 126-230 — Crystal structure of wild-type rabbit prp 126-230 — X-ray structure, 2010 (PDB 3O79), downloaded from the RCSB Protein Data Bank.
Globular domain of sheep prion protein — The crystal structure of the globular domain of sheep prion protein — X-ray structure, 2004 (PDB 1UW3), downloaded from the RCSB Protein Data Bank.
Segment from bank vole prion protein 168-176 QYNNQNNFV (6AXZ) — Segment from bank vole prion protein 168-176 qynnqnnfv — Cryo-EM structure, 2018 (PDB 6AXZ), downloaded from the RCSB Protein Data Bank.
Segment from bank vole prion protein 168-176 QYNNQNNFV (6BTK) — Segment from bank vole prion protein 168-176 qynnqnnfv — X-ray structure, 2018 (PDB 6BTK), downloaded from the RCSB Protein Data Bank.
Segment from the Y169F mutant of the bank vole prion protein 168-176… — Segment from the y169f mutant of the bank vole prion protein 168-176 qfnnqnnfv — Cryo-EM structure, 2022 (PDB 7RVF), downloaded from the RCSB Protein Data Bank.
The L1 amyloid-beta(1-40)fibril in the presence of anle138b… (9RAX) — The l1 amyloid-beta(1-40)fibril in the presence of anle138b (pre-treatment) — Cryo-EM structure, 2025 (PDB 9RAX), downloaded from the RCSB Protein Data Bank.
FD4-bound alpha-synuclein fibril polymorph 6A6B — Cryo-em structure of fd4-bound alpha-synuclein fibril polymorph 6a6b — Cryo-EM structure, 2025 (PDB 9KCN), downloaded from the RCSB Protein Data Bank.
Filament of D-TLKIVWI, a D-peptide that disaggregates Alzheimer's… — Filament of d-tlkivwi, a d-peptide that disaggregates alzheimer's paired helical filaments, determined by cryo-em — Cryo-EM structure, 2025 (PDB 9B4I), downloaded from the RCSB Protein Data Bank.
F0502B-bound E46K alpha-synuclein fibril — F0502b-bound e46k alpha-synuclein fibril — Cryo-EM structure, 2024 (PDB 8ZLO), downloaded from the RCSB Protein Data Bank.
Cryo EM structure of the type 5A polymorph of alpha-synuclein — Cryo em structure of the type 5a polymorph of alpha-synuclein. — Cryo-EM structure, 2024 (PDB 8PK4), downloaded from the RCSB Protein Data Bank.
Paired helical tau filament extracted from PrP-CAA Patient brain… — Paired helical tau filament extracted from prp-caa patient brain tissue | tau filament | phf tau — Cryo-EM structure, 2021 (PDB 7MKF), downloaded from the RCSB Protein Data Bank.
TASNSS segment from the R4-R5 loop of the E. coli Biofilm-associated… — Crystal structure of the tasnss segment from the r4-r5 loop of the e. coli biofilm-associated csga curli protein — X-ray structure, 2019 (PDB 6G9G), downloaded from the RCSB Protein Data Bank.
Amyloid-like LNIYQY segment from the R1 repeat of the E. coli… — Crystal structure of the amyloid-like lniyqy segment from the r1 repeat of the e. coli biofilm-associated csga curli protein — X-ray structure, 2019 (PDB 6G8D), downloaded from the RCSB Protein Data Bank.
Munc13-1 MUN Domain and Synaptobrevin-2 Juxtamembrane Linker Region — Crystal structure of munc13-1 mun domain and synaptobrevin-2 juxtamembrane linker region — X-ray structure, 2019 (PDB 6A30), downloaded from the RCSB Protein Data Bank.
Unc18-syntaxin 1 complex from Monosiga brevicollis — Crystal structure of the unc18-syntaxin 1 complex from monosiga brevicollis — X-ray structure, 2011 (PDB 2XHE), downloaded from the RCSB Protein Data Bank.
Analysis of human synaptotagmin 1 C2A-C2B — Crystal structure analysis of human synaptotagmin 1 c2a-c2b — X-ray structure, 2008 (PDB 2R83), downloaded from the RCSB Protein Data Bank.
Tau filament (10KR) — Cryo-em structure of tau filament — Cryo-EM structure, 2026 (PDB 10KR), downloaded from the RCSB Protein Data Bank.
NNQNTF segment from elk prion — Nnqntf segment from elk prion — X-ray structure, 2009 (PDB 3FVA), downloaded from the RCSB Protein Data Bank.
Q172E mutant of the bank vole prion protein 168-176 QYNNENNFV — Q172e mutant of the bank vole prion protein 168-176 qynnennfv — Cryo-EM structure, 2022 (PDB 7RVH), downloaded from the RCSB Protein Data Bank.
Ovine recombinant PrP(114-234), ARQ variant — Ovine recombinant prp(114-234), arq variant in complex with the fab of the vrq14 antibody — X-ray structure, 2004 (PDB 1TPX), downloaded from the RCSB Protein Data Bank.
Torpedo acetylcholine receptor in complex with d-tubocurarine — Cryo-em structure of torpedo acetylcholine receptor in complex with d-tubocurarine — Cryo-EM structure, 2022 (PDB 7SMS), downloaded from the RCSB Protein Data Bank.
Torpedo nicotinic acetylcholine receptor (8F6Y) — Cryo-em structure of torpedo nicotinic acetylcholine receptor in complex with etomidate, desensitized-like state — Cryo-EM structure, 2023 (PDB 8F6Y), downloaded from the RCSB Protein Data Bank.
Torpedo muscle-type nicotinic acetylcholine receptor -… (7QL5) — Torpedo muscle-type nicotinic acetylcholine receptor - nicotine-bound conformation — Cryo-EM structure, 2022 (PDB 7QL5), downloaded from the RCSB Protein Data Bank.
Torpedo acetylcholine receptor (7SMR) — Cryo-em structure of torpedo acetylcholine receptor in complex with carbachol, desensitized state — Cryo-EM structure, 2022 (PDB 7SMR), downloaded from the RCSB Protein Data Bank.
Torpedo acetylcholine receptor (7SMT) — Cryo-em structure of torpedo acetylcholine receptor in complex with d-tubocurarine and carbachol — Cryo-EM structure, 2022 (PDB 7SMT), downloaded from the RCSB Protein Data Bank.
Torpedo acetylcholine receptor in complex with alpha-bungarotoxin — Cryo-em structure of torpedo acetylcholine receptor in complex with alpha-bungarotoxin — Cryo-EM structure, 2020 (PDB 6UWZ), downloaded from the RCSB Protein Data Bank.
Torpedo nicotinic acetylcholine receptor (7Z14) — Cryo-em structure of torpedo nicotinic acetylcholine receptor in complex with a short-chain neurotoxin. — Cryo-EM structure, 2022 (PDB 7Z14), downloaded from the RCSB Protein Data Bank.
ABC-transporter choline binding protein in complex with acetylcholine — Abc-transporter choline binding protein in complex with acetylcholine — X-ray structure, 2008 (PDB 2RIN), downloaded from the RCSB Protein Data Bank.
Chimeric acetylcholine binding protein from Aplysia californica… — Crystal structure of a chimeric acetylcholine binding protein from aplysia californica (ac-achbp) containing loop c from the human alpha 3 nicotinic acetylcholine receptor in complex with cytisine — X-ray structure, 2016 (PDB 5SYO), downloaded from the RCSB Protein Data Bank.
Torpedo nicotinic acetylcholine receptor (8F6Z) — Cryo-em structure of torpedo nicotinic acetylcholine receptor in complex with succinylcholine, desensitized-like state — Cryo-EM structure, 2023 (PDB 8F6Z), downloaded from the RCSB Protein Data Bank.
Acetylcholine bound to a prokaryotic pentameric ligand-gated ion… — Crystal structure of acetylcholine bound to a prokaryotic pentameric ligand-gated ion channel, elic — X-ray structure, 2012 (PDB 3RQW), downloaded from the RCSB Protein Data Bank.
Torpedo nicotinic acetylcholine receptor (8F2S) — Cryo-em structure of torpedo nicotinic acetylcholine receptor in complex with rocuronium, pore-blocked state — Cryo-EM structure, 2023 (PDB 8F2S), downloaded from the RCSB Protein Data Bank.
Extracellular domain of alpha2 nicotinic acetylcholine receptor in… — Crystal structure of the extracellular domain of alpha2 nicotinic acetylcholine receptor in pentameric assembly — X-ray structure, 2016 (PDB 5FJV), downloaded from the RCSB Protein Data Bank.
Torpedo muscle-type nicotinic acetylcholine receptor - Monoliganded… — Torpedo muscle-type nicotinic acetylcholine receptor - monoliganded state — Cryo-EM structure, 2025 (PDB 9E3G), downloaded from the RCSB Protein Data Bank.
Chronic wasting disease prion fibril — Chronic wasting disease prion fibril — Cryo-EM structure, 2024 (PDB 9DMY), downloaded from the RCSB Protein Data Bank.
Torpedo muscle-type nicotinic acetylcholine receptor -… (7QL6) — Torpedo muscle-type nicotinic acetylcholine receptor - carbamylcholine-bound conformation — Cryo-EM structure, 2022 (PDB 7QL6), downloaded from the RCSB Protein Data Bank.
Acetylcholine binding protein (AChBP) complexed with a small molecule — X-ray structure of acetylcholine binding protein (achbp) complexed with a small molecule — X-ray structure, 2018 (PDB 5Y2Q), downloaded from the RCSB Protein Data Bank.
Aplysia californica AChBP in complex with Cytisine — Aplysia californica achbp in complex with cytisine — X-ray structure, 2013 (PDB 4BQT), downloaded from the RCSB Protein Data Bank.
Aplysia californica AChBP in complex with Varenicline — Aplysia californica achbp in complex with varenicline — X-ray structure, 2012 (PDB 4AFT), downloaded from the RCSB Protein Data Bank.