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Toxins, hormones & growth factors (PDB): 80 3D models

DNA, RNA, nucleic-acid drugs, gene editing, proteins and 300+ real PDB structures (real sizes 1–100 nm). Each one is a ready-made 3D model you can turn, recolour and place in a figure — open BioDioRama and type its name in the Library search.

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Anthrax protective antigen pore — Cryoem single particle reconstruction of anthrax toxin protective antigen pore at 2.9 angstrom resolution — cryo-EM structure, 2015 (PDB 3J9C), downloaded from the RCSB Protein Data Bank.
Neurophysin with vasopressin — Des 1-6 bovine neurophysin ii complex with vasopressin — X-ray structure, 2003 (PDB 1JK4), downloaded from the RCSB Protein Data Bank.
Cholera toxin — Cholera toxin — X-ray structure, 1996 (PDB 1XTC), downloaded from the RCSB Protein Data Bank.
Diphtheria toxin — The refined structure of dimeric diphtheria toxin at 2.0 angstroms resolution — X-ray structure, 1994 (PDB 1DDT), downloaded from the RCSB Protein Data Bank.
Anthrax protective antigen — Anthrax protective antigen — X-ray structure, 1998 (PDB 1ACC), downloaded from the RCSB Protein Data Bank.
Botulinum neurotoxin A — Crystal structure of botulinum neurotoxin serotype a — X-ray structure, 1999 (PDB 3BTA), downloaded from the RCSB Protein Data Bank.
Ricin — Crystallographic refinement of ricin to 2.5 angstroms — X-ray structure, 1994 (PDB 2AAI), downloaded from the RCSB Protein Data Bank.
Leptin — Human obesity protein, leptin — X-ray structure, 1998 (PDB 1AX8), downloaded from the RCSB Protein Data Bank.
Growth hormone with receptor — Human growth hormone and extracellular domain of its receptor: crystal structure of the complex — X-ray structure, 1994 (PDB 3HHR), downloaded from the RCSB Protein Data Bank.
Erythropoietin with receptor — Crystal structure of human erythropoietin complexed to its receptor at 1.9 angstroms — X-ray structure, 1999 (PDB 1EER), downloaded from the RCSB Protein Data Bank.
VEGF — Vascular endothelial growth factor refined to 1.93 angstroms resolution — X-ray structure, 1998 (PDB 2VPF), downloaded from the RCSB Protein Data Bank.
BMP-2 — Human bone morphogenetic protein-2 (bmp-2) — X-ray structure, 2000 (PDB 3BMP), downloaded from the RCSB Protein Data Bank.
Nerve growth factor — New protein fold revealed by a 2.3 angstrom resolution crystal structure of nerve growth factor — X-ray structure, 1994 (PDB 1BET), downloaded from the RCSB Protein Data Bank.
TGF-β1 — Solution structure of tgf-b1, nmr, models 1-17 of 33 structures — NMR structure, 1996 (PDB 1KLA), downloaded from the RCSB Protein Data Bank.
Epidermal growth factor — Solution structure of murine epidermal growth factor determined by nmr spectroscopy and refined by energy minimization with restraints — NMR structure, 1994 (PDB 1EGF), downloaded from the RCSB Protein Data Bank.
Pea lectin — Design, expression, and crystallization of recombinant lectin from the garden pea (pisum sativum) — X-ray structure, 1990 (PDB 2LTN), downloaded from the RCSB Protein Data Bank.
Human growth hormone — Human growth hormone — X-ray structure, 1995 (PDB 1HGU), downloaded from the RCSB Protein Data Bank.
Growth hormone receptor complex — Human growth hormone bound to single receptor — X-ray structure, 1998 (PDB 1A22), downloaded from the RCSB Protein Data Bank.
Pertussis toxin — The crystal structure of pertussis toxin — X-ray structure, 1995 (PDB 1PRT), downloaded from the RCSB Protein Data Bank.
Heat-labile enterotoxin — Refined structure of e. coli heat labile enterotoxin, a close relative of cholera toxin — X-ray structure, 1994 (PDB 1LTS), downloaded from the RCSB Protein Data Bank.
Abrin — Crystal structure of abrin-a — X-ray structure, 1995 (PDB 1ABR), downloaded from the RCSB Protein Data Bank.
Botulinum neurotoxin B — Crystal structure of clostridium neurotoxin type b — X-ray structure, 2000 (PDB 1EPW), downloaded from the RCSB Protein Data Bank.
Tetanus toxin fragment — Tetanus toxin c fragment — X-ray structure, 1998 (PDB 1A8D), downloaded from the RCSB Protein Data Bank.
Heat-labile enterotoxin IIb — Escherichia coli heat labile enterotoxin type iib — X-ray structure, 1996 (PDB 1TII), downloaded from the RCSB Protein Data Bank.
Exotoxin A — Pseudomonas aeruginosa exotoxin a, wild type — X-ray structure, 2001 (PDB 1IKQ), downloaded from the RCSB Protein Data Bank.
Anthrax lethal factor — Anthrax toxin lethal factor — X-ray structure, 2001 (PDB 1J7N), downloaded from the RCSB Protein Data Bank.
Anthrax PA with receptor — Crystal structure of b. anthracis protective antigen complexed with human anthrax toxin receptor — X-ray structure, 2004 (PDB 1T6B), downloaded from the RCSB Protein Data Bank.
Pneumolysin — Structure of pneumolysin at 1.98 a resolution — X-ray structure, 2015 (PDB 5CR6), downloaded from the RCSB Protein Data Bank.
Perfringolysin O — Perfringolysin o — X-ray structure, 1998 (PDB 1PFO), downloaded from the RCSB Protein Data Bank.
β-Bungarotoxin — Structure of beta2-bungarotoxin: potassium channel binding by kunitz modules and targeted phospholipase action — X-ray structure, 1996 (PDB 1BUN), downloaded from the RCSB Protein Data Bank.
α-Bungarotoxin — alpha-bungarotoxin complexed with high affinity peptide — X-ray structure, 2001 (PDB 1HC9), downloaded from the RCSB Protein Data Bank.
α-Bungarotoxin — The crystal structure of alpha-bungarotoxin at 2.5 angstroms resolution. relation to solution structure and binding to acetylcholine rece… — X-ray structure, 1986 (PDB 2ABX), downloaded from the RCSB Protein Data Bank.
Erabutoxin (snake toxin) — Erabutoxin — X-ray structure, 1999 (PDB 1QKD), downloaded from the RCSB Protein Data Bank.
Conotoxin — Solution structure of alpha-conotoxin auib — NMR structure, 2002 (PDB 1MXN), downloaded from the RCSB Protein Data Bank.
Interleukin-6 — Human interleukin-6, nmr, minimized average structure — NMR structure, 1998 (PDB 1IL6), downloaded from the RCSB Protein Data Bank.
Interleukin-6 — Human interleukin-6 — X-ray structure, 1998 (PDB 1ALU), downloaded from the RCSB Protein Data Bank.
IL-6–IL-6R–gp130 hexamer — Crystal structure of the hexameric human il-6/il-6 alpha receptor/gp130 complex — X-ray structure, 2003 (PDB 1P9M), downloaded from the RCSB Protein Data Bank.
IL-1β with its receptor — Type-1 interleukin-1 receptor complexed with interleukin-1 beta — X-ray structure, 1998 (PDB 1ITB), downloaded from the RCSB Protein Data Bank.
Cytokine–receptor complex — Crystal structure of a cytokine/receptor complex — X-ray structure, 2001 (PDB 1I1R), downloaded from the RCSB Protein Data Bank.
IL-2 receptor complex — cytokine receptor complex — X-ray structure, 2005 (PDB 2B5I), downloaded from the RCSB Protein Data Bank.
IL-2 with IL-2Rα — structure of interleukin-2 with its alpha receptor — X-ray structure, 2005 (PDB 1Z92), downloaded from the RCSB Protein Data Bank.
IL-4 with common γ-chain — Interleukin-4 mutant rga bound to cytokine receptor common gamma — X-ray structure, 2012 (PDB 3QB7), downloaded from the RCSB Protein Data Bank.
Interleukin-4 — Interleukin-4 (wild-type) — X-ray structure, 1996 (PDB 1HIK), downloaded from the RCSB Protein Data Bank.
Interferon-β — Human interferon-beta crystal structure — X-ray structure, 1998 (PDB 1AU1), downloaded from the RCSB Protein Data Bank.
EPO with its receptor — Erythropoietin complexed with extracellular domains of erythropoietin receptor — X-ray structure, 1999 (PDB 1CN4), downloaded from the RCSB Protein Data Bank.
IGF-I — Human insulin-like growth factor; esrf data — X-ray structure, 2002 (PDB 1GZR), downloaded from the RCSB Protein Data Bank.
G-CSF receptor signalling complex — Crystal structure of the human gcsf-receptor signaling complex — X-ray structure, 2006 (PDB 2D9Q), downloaded from the RCSB Protein Data Bank.
G-CSF — The structure of granulocyte-colony-stimulating factor and its relationship to those of other growth factors — X-ray structure, 1994 (PDB 1RHG), downloaded from the RCSB Protein Data Bank.
GM-CSF — Three-dimensional structure of recombinant human granulocyte-macrophage colony-stimulating factor — X-ray structure, 1993 (PDB 1CSG), downloaded from the RCSB Protein Data Bank.
VEGF with receptor — Vegf in complex with domain 2 of the flt-1 receptor — X-ray structure, 1999 (PDB 1FLT), downloaded from the RCSB Protein Data Bank.
VEGF-A receptor-binding domain — crystal structure of human vegf-a receptor binding domain — X-ray structure, 2014 (PDB 4KZN), downloaded from the RCSB Protein Data Bank.
VEGF with VEGFR — Vegfr-2/vegf-a complex structure — X-ray structure, 2012 (PDB 3V2A), downloaded from the RCSB Protein Data Bank.
TGF-β receptor complex — Ternary complex of tgf-b1 reveals isoform-specific ligand recognition and receptor recruitment in the superfamily — X-ray structure, 2010 (PDB 3KFD), downloaded from the RCSB Protein Data Bank.
BMP-2 with receptor — Structural refinement of the complex of bone morphogenetic protein 2 and its type ia receptor — X-ray structure, 2004 (PDB 1REW), downloaded from the RCSB Protein Data Bank.
TGF-β ligand–receptor complex — Crystal structure of a tgf-beta ligand-receptor complex — X-ray structure, 2012 (PDB 3QB4), downloaded from the RCSB Protein Data Bank.
Nerve growth factor (β-NGF) — Crystal structure of beta nerve growth factor at 2.5 a resolution in c2 space group with zn ions bound — X-ray structure, 1996 (PDB 1BTG), downloaded from the RCSB Protein Data Bank.
NGF with TrkA — Ngf in complex with domain 5 of the trka receptor — X-ray structure, 1999 (PDB 1WWW), downloaded from the RCSB Protein Data Bank.
BDNF–NT-3 heterodimer — Structure of the brain-derived neurotrophic factor(slash)neurotrophin 3 heterodimer — X-ray structure, 1996 (PDB 1BND), downloaded from the RCSB Protein Data Bank.
TrkB with neurotrophin-4/5 — Crystal structure of trkb-d5 bound to neurotrophin-4/5 — X-ray structure, 2001 (PDB 1HCF), downloaded from the RCSB Protein Data Bank.
Insulin (human) — Human insulin mutant serb9glu — X-ray structure, 1999 (PDB 1B9E), downloaded from the RCSB Protein Data Bank.
IGF-II — Solution structure of human insulin-like growth factor ii relationship to receptor and binding protein interactions — NMR structure, 1995 (PDB 1IGL), downloaded from the RCSB Protein Data Bank.
IGF-I — Three-dimensional structure of human insulin-like growth factor-i (igf-i) determined by 1h-nmr and distance geometry, 6 structures — NMR structure, 1999 (PDB 1BQT), downloaded from the RCSB Protein Data Bank.
Insulin–receptor — Structural basis for the inhibition of insulin-like growth factors by igf binding proteins — X-ray structure, 2006 (PDB 2DSR), downloaded from the RCSB Protein Data Bank.
Growth hormone with two receptors — 1:2 complex of human growth hormone with its soluble binding protein — X-ray structure, 1997 (PDB 1HWG), downloaded from the RCSB Protein Data Bank.
Follicle-stimulating hormone — Human follicle stimulating hormone — X-ray structure, 2001 (PDB 1FL7), downloaded from the RCSB Protein Data Bank.
Human chorionic gonadotropin — Structure of human chorionic gonadotropin at 2.6 angstroms resolution from mad analysis of the selenomethionyl protein — X-ray structure, 1994 (PDB 1HCN), downloaded from the RCSB Protein Data Bank.
hCG with antibody Fvs — Ternary complex of human chorionic gonadotropin with fv anti alpha subunit and fv anti beta subunit — X-ray structure, 2000 (PDB 1QFW), downloaded from the RCSB Protein Data Bank.
Glucagon receptor — Structure of the class b human glucagon g protein coupled receptor — X-ray structure, 2013 (PDB 4L6R), downloaded from the RCSB Protein Data Bank.
Glucagon receptor with peptide — Structure of the glucagon receptor in complex with a glucagon analogue — X-ray structure, 2018 (PDB 5YQZ), downloaded from the RCSB Protein Data Bank.
GLP-1R with GLP-1 and Gs — 3.3 angstrom phase-plate cryo-em structure of a biased agonist-bound human glp-1 receptor-gs complex — cryo-EM structure, 2018 (PDB 6B3J), downloaded from the RCSB Protein Data Bank.
GLP-1R — Crystal structure of thermostabilised full-length glp-1r in complex with a truncated peptide agonist at 3.7 a resolution — X-ray structure, 2017 (PDB 5NX2), downloaded from the RCSB Protein Data Bank.
GIP hormone — Solution structure of gip in tfe/water — NMR structure, 2007 (PDB 2OBU), downloaded from the RCSB Protein Data Bank.
Neurophysin–oxytocin — Bovine neurophysin ii complex with oxytocin — X-ray structure, 1997 (PDB 1NPO), downloaded from the RCSB Protein Data Bank.
FGF2 (basic FGF) — Crystal structure of basic fibroblast growth factor at 1.6 angstroms resolution — X-ray structure, 1994 (PDB 1BFG), downloaded from the RCSB Protein Data Bank.
FGF2–FGFR1–heparin — Crystal structure of a ternary fgf2-fgfr1-heparin complex — X-ray structure, 2000 (PDB 1FQ9), downloaded from the RCSB Protein Data Bank.
FGF2–FGFR1 dimer — Crystal structure of a dimeric fgf2-fgfr1 complex — X-ray structure, 2000 (PDB 1CVS), downloaded from the RCSB Protein Data Bank.
Epidermal growth factor (human) — Crystal structure of human epidermal growth factor — X-ray structure, 2001 (PDB 1JL9), downloaded from the RCSB Protein Data Bank.
EGFR–TGF-α — Crystal structure of human epidermal growth factor receptor (residues 1-501) in complex with tgf-alpha — X-ray structure, 2003 (PDB 1MOX), downloaded from the RCSB Protein Data Bank.
HER2 ectodomain — Crystal structure of erbb2 domains 1-3 — X-ray structure, 2005 (PDB 2A91), downloaded from the RCSB Protein Data Bank.
HER2 with pertuzumab — Insights into erbb signaling from the structure of the erbb2-pertuzumab complex — X-ray structure, 2004 (PDB 1S78), downloaded from the RCSB Protein Data Bank.